Hnrnpm (heterogeneous nuclear ribonucleoprotein M) - Rat Genome Database

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Gene: Hnrnpm (heterogeneous nuclear ribonucleoprotein M) Rattus norvegicus
Analyze
Symbol: Hnrnpm
Name: heterogeneous nuclear ribonucleoprotein M
RGD ID: 620369
Description: Enables calcium-dependent protein binding activity and protein antigen binding activity. Involved in several processes, including cellular response to carcinoembryonic antigen; cellular response to lipopolysaccharide; and positive regulation of protein localization. Located in cell surface. Is active in glutamatergic synapse and postsynaptic density. Orthologous to human HNRNPM (heterogeneous nuclear ribonucleoprotein M); PARTICIPATES IN spliceosome pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hnRNP M; Hnrpm; Hnrpm4; M4 protein; MGC109545
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8715,140,877 - 15,178,871 (-)NCBIGRCr8
mRatBN7.2714,438,703 - 14,476,781 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl714,438,688 - 14,476,762 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx717,447,326 - 17,485,310 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0719,312,377 - 19,350,433 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0717,192,913 - 17,230,901 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0718,516,253 - 18,554,536 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl718,516,512 - 18,554,227 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0718,693,853 - 18,731,993 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4716,150,060 - 16,188,054 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1716,150,062 - 16,188,046 (-)NCBI
Celera713,337,407 - 13,375,335 (-)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
3',5'-cyclic UMP  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
7,12-dimethyltetraphene  (EXP)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
azoxystrobin  (ISO)
beauvericin  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
buspirone  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (EXP,ISO)
chromium(6+)  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
deguelin  (ISO)
dibutyl phthalate  (EXP)
diuron  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
enniatin  (ISO)
enzyme inhibitor  (ISO)
fenpyroximate  (ISO)
fenthion  (ISO)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
glyphosate  (ISO)
hydrogen peroxide  (ISO)
inulin  (ISO)
isoflavones  (EXP)
ivermectin  (ISO)
lead(0)  (ISO)
linsidomine  (EXP)
lipopolysaccharide  (EXP,ISO)
mancozeb  (ISO)
methapyrilene  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
PCB138  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
picoxystrobin  (ISO)
pterostilbene  (ISO)
pyrimidifen  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
selenium atom  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (EXP)
thifluzamide  (ISO)
titanium dioxide  (ISO)
toluene  (EXP)
trichloroethene  (EXP)
triptonide  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Surface expression of heterogeneous nuclear RNA binding protein M4 on Kupffer cell relates to its function as a carcinoembryonic antigen receptor. Bajenova O, etal., Exp Cell Res. 2003 Nov 15;291(1):228-41.
2. Heterogeneous RNA-binding protein M4 is a receptor for carcinoembryonic antigen in Kupffer cells. Bajenova OV, etal., J Biol Chem 2001 Aug 17;276(33):31067-73.
3. Identification of HnRNP M as a novel biomarker for colorectal carcinoma by quantitative proteomics. Chen S, etal., Am J Physiol Gastrointest Liver Physiol. 2014 Mar 1;306(5):G394-403. doi: 10.1152/ajpgi.00328.2013. Epub 2013 Dec 31.
4. Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes expands the catalog of participating factors. Chen YI, etal., Nucleic Acids Res. 2007;35(12):3928-44. Epub 2007 May 30.
5. A population of rat liver lysosomes responsible for the selective uptake and degradation of cytosolic proteins. Cuervo AM, etal., J Biol Chem. 1997 Feb 28;272(9):5606-15.
6. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
8. Rhythmic serotonin N-acetyltransferase mRNA degradation is essential for the maintenance of its circadian oscillation. Kim TD, etal., Mol Cell Biol. 2005 Apr;25(8):3232-46.
9. Microarray study of gene expression in uterine leiomyoma. Litovkin KV, etal., Exp Oncol. 2008 Jun;30(2):106-11.
10. hnRNP M interacts with PSF and p54(nrb) and co-localizes within defined nuclear structures. Marko M, etal., Exp Cell Res. 2010 Feb 1;316(3):390-400. doi: 10.1016/j.yexcr.2009.10.021. Epub 2009 Oct 27.
11. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
12. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. The spliceosome: design principles of a dynamic RNP machine. Wahl MC, etal., Cell. 2009 Feb 20;136(4):701-18. doi: 10.1016/j.cell.2009.02.009.
16. RNA binding proteins accumulate at the postsynaptic density with synaptic activity. Zhang G, etal., J Neurosci. 2012 Jan 11;32(2):599-609. doi: 10.1523/JNEUROSCI.2463-11.2012.
Additional References at PubMed
PMID:9731529   PMID:10947964   PMID:11984006   PMID:11991638   PMID:12477932   PMID:15489334   PMID:16128803   PMID:19946888   PMID:22082260   PMID:22658674   PMID:22681889   PMID:23533145  
PMID:23658023   PMID:23979707   PMID:24625528   PMID:29476059   PMID:30053369   PMID:35352799  


Genomics

Comparative Map Data
Hnrnpm
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8715,140,877 - 15,178,871 (-)NCBIGRCr8
mRatBN7.2714,438,703 - 14,476,781 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl714,438,688 - 14,476,762 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx717,447,326 - 17,485,310 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0719,312,377 - 19,350,433 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0717,192,913 - 17,230,901 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0718,516,253 - 18,554,536 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl718,516,512 - 18,554,227 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0718,693,853 - 18,731,993 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4716,150,060 - 16,188,054 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1716,150,062 - 16,188,046 (-)NCBI
Celera713,337,407 - 13,375,335 (-)NCBICelera
Cytogenetic Map7q13NCBI
HNRNPM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38198,444,975 - 8,489,114 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl198,444,767 - 8,489,114 (+)EnsemblGRCh38hg38GRCh38
GRCh37198,509,859 - 8,553,998 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36198,415,803 - 8,459,998 (+)NCBINCBI36Build 36hg18NCBI36
Build 34198,415,650 - 8,459,994NCBI
Celera198,367,796 - 8,411,661 (+)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef198,165,461 - 8,209,438 (+)NCBIHuRef
CHM1_1198,509,226 - 8,553,070 (+)NCBICHM1_1
T2T-CHM13v2.0198,432,898 - 8,476,696 (+)NCBIT2T-CHM13v2.0
Hnrnpm
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391733,865,207 - 33,904,432 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1733,865,207 - 33,905,834 (-)EnsemblGRCm39 Ensembl
GRCm381733,646,233 - 33,685,458 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1733,646,233 - 33,686,860 (-)EnsemblGRCm38mm10GRCm38
MGSCv371733,783,178 - 33,822,403 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361733,252,927 - 33,292,090 (-)NCBIMGSCv36mm8
Celera1736,401,579 - 36,440,923 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
Hnrnpm
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955563933,824 - 975,064 (-)NCBIChiLan1.0ChiLan1.0
HNRNPM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22013,113,011 - 13,157,166 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11912,230,568 - 12,274,708 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0197,731,828 - 7,776,101 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1198,579,206 - 8,624,029 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl198,579,211 - 8,624,029 (+)Ensemblpanpan1.1panPan2
HNRNPM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12052,993,934 - 53,034,608 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2052,993,824 - 53,034,606 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2052,795,007 - 52,835,710 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02053,521,997 - 53,562,739 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2053,521,888 - 53,562,740 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12052,723,883 - 52,764,539 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02053,169,742 - 53,210,895 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02053,401,382 - 53,442,032 (+)NCBIUU_Cfam_GSD_1.0
Hnrnpm
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118212,550,835 - 212,612,298 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365885,241,613 - 5,283,689 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0 EnsemblNW_0049365885,222,509 - 5,239,890 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365885,241,276 - 5,283,952 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HNRNPM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl270,813,745 - 70,862,586 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1270,813,745 - 70,858,903 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2271,180,163 - 71,225,248 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HNRNPM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.167,795,996 - 7,839,506 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl67,796,045 - 7,839,244 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607412,421,268 - 12,463,541 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hnrnpm
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248281,199,048 - 1,250,887 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hnrnpm
77 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:376
Count of miRNA genes:135
Interacting mature miRNAs:144
Transcripts:ENSRNOT00000011047, ENSRNOT00000036172, ENSRNOT00000059985
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat

Markers in Region
RH132782  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2714,476,872 - 14,477,081 (+)MAPPERmRatBN7.2
Rnor_6.0718,554,423 - 18,554,631NCBIRnor6.0
Rnor_5.0718,732,023 - 18,732,231UniSTSRnor5.0
RGSC_v3.4716,188,229 - 16,188,437UniSTSRGSC3.4
Celera713,375,510 - 13,375,718UniSTS
Cytogenetic Map7q12UniSTS
RH143889  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2714,447,602 - 14,447,821 (+)MAPPERmRatBN7.2
Rnor_6.0718,525,154 - 18,525,372NCBIRnor6.0
Rnor_5.0718,702,754 - 18,702,972UniSTSRnor5.0
RGSC_v3.4716,158,960 - 16,159,178UniSTSRGSC3.4
Celera713,346,241 - 13,346,459UniSTS
RH 3.4 Map769.0UniSTS
Cytogenetic Map7q12UniSTS
RH143934  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2714,439,870 - 14,440,027 (+)MAPPERmRatBN7.2
Rnor_6.0718,517,421 - 18,517,577NCBIRnor6.0
Rnor_5.0718,695,021 - 18,695,177UniSTSRnor5.0
RGSC_v3.4716,151,228 - 16,151,384UniSTSRGSC3.4
Celera713,338,575 - 13,338,731UniSTS
Cytogenetic Map7q12UniSTS
RH144620  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2714,465,711 - 14,465,896 (+)MAPPERmRatBN7.2
Rnor_6.0718,543,262 - 18,543,446NCBIRnor6.0
Rnor_5.0718,720,862 - 18,721,046UniSTSRnor5.0
RGSC_v3.4716,177,068 - 16,177,252UniSTSRGSC3.4
Celera713,364,349 - 13,364,533UniSTS
RH 3.4 Map796.3UniSTS
Cytogenetic Map7q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000011047   ⟹   ENSRNOP00000011047
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl714,438,708 - 14,476,762 (-)Ensembl
Rnor_6.0 Ensembl718,516,512 - 18,554,227 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000036172   ⟹   ENSRNOP00000032108
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl714,438,708 - 14,476,762 (-)Ensembl
Rnor_6.0 Ensembl718,516,512 - 18,554,227 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000094545   ⟹   ENSRNOP00000084866
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl714,438,688 - 14,476,724 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000096470   ⟹   ENSRNOP00000080170
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl714,438,706 - 14,476,719 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000102040   ⟹   ENSRNOP00000087580
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl714,440,323 - 14,476,724 (-)Ensembl
RefSeq Acc Id: NM_001109911   ⟹   NP_001103381
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8715,140,877 - 15,178,871 (-)NCBI
mRatBN7.2714,438,703 - 14,476,698 (-)NCBI
Rnor_6.0718,516,253 - 18,554,248 (-)NCBI
Rnor_5.0718,693,853 - 18,731,993 (-)NCBI
RGSC_v3.4716,150,060 - 16,188,054 (-)RGD
Celera713,337,407 - 13,375,335 (-)RGD
Sequence:
RefSeq Acc Id: NM_053876   ⟹   NP_446328
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8715,140,877 - 15,178,871 (-)NCBI
mRatBN7.2714,438,703 - 14,476,698 (-)NCBI
Rnor_6.0718,516,253 - 18,554,248 (-)NCBI
Rnor_5.0718,693,853 - 18,731,993 (-)NCBI
RGSC_v3.4716,150,060 - 16,188,054 (-)RGD
Celera713,337,407 - 13,375,335 (-)RGD
Sequence:
RefSeq Acc Id: XM_063262869   ⟹   XP_063118939
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8715,140,877 - 15,164,959 (-)NCBI
RefSeq Acc Id: XM_063262870   ⟹   XP_063118940
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8715,140,877 - 15,164,959 (-)NCBI
RefSeq Acc Id: NP_446328   ⟸   NM_053876
- Peptide Label: isoform b
- UniProtKB: Q5M815 (UniProtKB/Swiss-Prot),   Q62826 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001103381   ⟸   NM_001109911
- Peptide Label: isoform a
- UniProtKB: A6KQH2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000032108   ⟸   ENSRNOT00000036172
RefSeq Acc Id: ENSRNOP00000011047   ⟸   ENSRNOT00000011047
RefSeq Acc Id: ENSRNOP00000084866   ⟸   ENSRNOT00000094545
RefSeq Acc Id: ENSRNOP00000080170   ⟸   ENSRNOT00000096470
RefSeq Acc Id: ENSRNOP00000087580   ⟸   ENSRNOT00000102040
RefSeq Acc Id: XP_063118940   ⟸   XM_063262870
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063118939   ⟸   XM_063262869
- Peptide Label: isoform X1
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62826-F1-model_v2 AlphaFold Q62826 1-690 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695082
Promoter ID:EPDNEW_R5607
Type:initiation region
Name:Hnrnpm_1
Description:heterogeneous nuclear ribonucleoprotein M
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0718,554,248 - 18,554,308EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620369 AgrOrtholog
BioCyc Gene G2FUF-34713 BioCyc
Ensembl Genes ENSRNOG00000007921 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011047 ENTREZGENE
  ENSRNOT00000011047.8 UniProtKB/TrEMBL
  ENSRNOT00000036172 ENTREZGENE
  ENSRNOT00000036172.7 UniProtKB/TrEMBL
  ENSRNOT00000094545.1 UniProtKB/TrEMBL
  ENSRNOT00000096470.1 UniProtKB/TrEMBL
  ENSRNOT00000102040.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7325202 IMAGE-MGC_LOAD
InterPro HnRNP_M_PY-NLS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hnRNPM_RRM3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:116655 UniProtKB/Swiss-Prot
MGC_CLONE MGC:109545 IMAGE-MGC_LOAD
NCBI Gene 116655 ENTREZGENE
PANTHER PTHR23003:SF6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam HnRNP_M UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hnrnpm PhenoGen
PROSITE RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007921 RatGTEx
SMART RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZQ38_RAT UniProtKB/TrEMBL
  A0A8I6A4N0_RAT UniProtKB/TrEMBL
  A0A8I6GC87_RAT UniProtKB/TrEMBL
  A6KQH2 ENTREZGENE, UniProtKB/TrEMBL
  A6KQH4_RAT UniProtKB/TrEMBL
  F1LV13_RAT UniProtKB/TrEMBL
  F1M3D3_RAT UniProtKB/TrEMBL
  HNRPM_RAT UniProtKB/Swiss-Prot
  Q5M815 ENTREZGENE
  Q62826 ENTREZGENE
UniProt Secondary Q5M815 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-13 Hnrnpm  heterogeneous nuclear ribonucleoprotein M  Hnrpm  heterogeneous nuclear ribonucleoprotein M  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Hnrpm  heterogeneous nuclear ribonucleoprotein M      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Hnrpm  heterogeneous nuclear ribonucleoprotein M      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains 3 putative RNA-binding domains, an arginine/methionine/glutamine-rich C terminus and 3 potential membrane spanning regions 632922
gene_protein a 78-kDa membrane protein 632922
gene_transcript 2.4-kilobase transcript 632922