(S)-nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of ASCL1 mRNA CTD PMID:28555334 1,8-cineole decreases expression ISO ASCL1 (Homo sapiens) 6480464 Eucalyptol results in decreased expression of ASCL1 mRNA CTD PMID:36331666 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of ASCL1 mRNA CTD PMID:30723492 17beta-estradiol multiple interactions ISO ASCL1 (Homo sapiens) 6480464 [Estradiol binds to ESR2 protein] which results in increased expression of ASCL1 mRNA and [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of ASCL1 mRNA CTD PMID:19619570 and PMID:20404318 17beta-estradiol decreases expression ISO ASCL1 (Homo sapiens) 6480464 Estradiol results in decreased expression of ASCL1 mRNA CTD PMID:31614463 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of ASCL1 mRNA CTD PMID:20068009 17beta-estradiol increases expression ISO ASCL1 (Homo sapiens) 6480464 Estradiol results in increased expression of ASCL1 mRNA CTD PMID:19619570 2,2',4,4'-Tetrabromodiphenyl ether decreases expression EXP 6480464 2 more ... CTD PMID:27291303 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Ascl1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of ASCL1 mRNA CTD PMID:21570461 and PMID:24058054 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of ASCL1 mRNA CTD PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO ASCL1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of ASCL1 mRNA CTD PMID:19619570 and PMID:19901195 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO ASCL1 (Homo sapiens) 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of ASCL1 mRNA CTD PMID:19619570 2,3,7,8-Tetrachlorodibenzofuran increases expression EXP 6480464 2 more ... CTD PMID:32109520 2,6-dinitrotoluene affects expression EXP 6480464 2 and 6-dinitrotoluene affects the expression of ASCL1 mRNA CTD PMID:21346803 2-methylcholine affects expression ISO ASCL1 (Homo sapiens) 6480464 beta-methylcholine affects the expression of ASCL1 mRNA CTD PMID:21179406 3-methylcholanthrene multiple interactions ISO Ascl1 (Mus musculus) 6480464 [Methylcholanthrene co-treated with Nanotubes and Carbon] results in increased expression of ASCL1 mRNA CTD PMID:25926378 4,4'-diaminodiphenylmethane increases expression ISO Ascl1 (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of ASCL1 mRNA CTD PMID:18648102 4,4'-sulfonyldiphenol decreases expression ISO Ascl1 (Mus musculus) 6480464 bisphenol S results in decreased expression of ASCL1 mRNA CTD PMID:30951980 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of ASCL1 mRNA CTD PMID:24780913 Actein decreases expression EXP 6480464 actein results in decreased expression of ASCL1 protein CTD PMID:29969672 afimoxifene decreases expression ISO ASCL1 (Homo sapiens) 6480464 afimoxifene results in decreased expression of ASCL1 mRNA CTD PMID:19901195 afimoxifene increases expression ISO ASCL1 (Homo sapiens) 6480464 afimoxifene results in increased expression of ASCL1 mRNA CTD PMID:16849584 aldehydo-D-glucose multiple interactions ISO Ascl1 (Mus musculus) 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of ASCL1 mRNA CTD PMID:37567420 all-trans-retinoic acid increases expression ISO ASCL1 (Homo sapiens) 6480464 Tretinoin results in increased expression of ASCL1 mRNA CTD PMID:21934132 all-trans-retinoic acid increases expression ISO Ascl1 (Mus musculus) 6480464 Tretinoin results in increased expression of ASCL1 mRNA CTD PMID:34627992 all-trans-retinoic acid decreases expression ISO ASCL1 (Homo sapiens) 6480464 Tretinoin results in decreased expression of ASCL1 mRNA CTD PMID:23724009 all-trans-retinol increases expression EXP 6480464 Vitamin A deficiency results in increased expression of ASCL1 mRNA CTD PMID:12555267 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of ASCL1 mRNA CTD PMID:16483693 arotinoid acid multiple interactions ISO ASCL1 (Homo sapiens) 6480464 [4-(2-(5 more ... CTD PMID:34480604 arsane decreases expression ISO Ascl1 (Mus musculus) 6480464 Arsenic results in decreased expression of ASCL1 mRNA CTD PMID:24019935 and PMID:33124703 arsenic atom decreases expression ISO Ascl1 (Mus musculus) 6480464 Arsenic results in decreased expression of ASCL1 mRNA CTD PMID:24019935 and PMID:33124703 atrazine decreases expression ISO ASCL1 (Homo sapiens) 6480464 Atrazine results in decreased expression of ASCL1 mRNA CTD PMID:22378314 benzo[a]pyrene affects methylation ISO ASCL1 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of ASCL1 3' UTR and Benzo(a)pyrene affects the methylation of ASCL1 exon CTD PMID:27901495 benzo[a]pyrene increases methylation ISO ASCL1 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of ASCL1 5' UTR and Benzo(a)pyrene results in increased methylation of ASCL1 promoter CTD PMID:27901495 bexarotene multiple interactions EXP 6480464 [bexarotene co-treated with Tamoxifen] results in decreased expression of ASCL1 mRNA CTD PMID:17630414 bis(2-ethylhexyl) phthalate multiple interactions ISO Ascl1 (Mus musculus) 6480464 [Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of ASCL1 mRNA CTD PMID:38199361 bisphenol A increases expression ISO Ascl1 (Mus musculus) 6480464 bisphenol A results in increased expression of ASCL1 mRNA CTD PMID:26063408 and PMID:30951980 bisphenol A affects methylation ISO Ascl1 (Mus musculus) 6480464 bisphenol A affects the methylation of ASCL1 promoter CTD PMID:27334623 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ASCL1 mRNA CTD PMID:25181051 and PMID:35192832 bisphenol F decreases expression ISO Ascl1 (Mus musculus) 6480464 bisphenol F results in decreased expression of ASCL1 mRNA CTD PMID:30951980 bosentan affects expression ISO ASCL1 (Homo sapiens) 6480464 Bosentan affects the expression of ASCL1 mRNA CTD PMID:29761207 carbon nanotube multiple interactions ISO Ascl1 (Mus musculus) 6480464 [Methylcholanthrene co-treated with Nanotubes and Carbon] results in increased expression of ASCL1 mRNA CTD PMID:25926378 carbon nanotube decreases expression ISO Ascl1 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 CHIR 99021 multiple interactions ISO ASCL1 (Homo sapiens) 6480464 [4-(2-(5 more ... CTD PMID:34480604 cortisol multiple interactions ISO ASCL1 (Homo sapiens) 6480464 [4-(2-(5 more ... CTD PMID:34480604 Cyclopamine decreases expression EXP 6480464 cyclopamine results in decreased expression of ASCL1 mRNA CTD PMID:21703336 D-glucose multiple interactions ISO Ascl1 (Mus musculus) 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of ASCL1 mRNA CTD PMID:37567420 decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of ASCL1 mRNA CTD PMID:23914054 deguelin increases expression ISO ASCL1 (Homo sapiens) 6480464 deguelin results in increased expression of ASCL1 mRNA CTD PMID:33512557 disodium selenite decreases expression ISO ASCL1 (Homo sapiens) 6480464 Sodium Selenite results in decreased expression of ASCL1 mRNA CTD PMID:18175754 dorsomorphin multiple interactions ISO ASCL1 (Homo sapiens) 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 ellagic acid increases expression ISO ASCL1 (Homo sapiens) 6480464 Ellagic Acid results in increased expression of ASCL1 mRNA CTD PMID:12002526 fructose multiple interactions ISO Ascl1 (Mus musculus) 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of ASCL1 mRNA CTD PMID:37567420 glucose multiple interactions ISO Ascl1 (Mus musculus) 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of ASCL1 mRNA CTD PMID:37567420 ketamine decreases expression EXP 6480464 Ketamine results in decreased expression of ASCL1 mRNA CTD PMID:20080153 L-ascorbic acid multiple interactions ISO ASCL1 (Homo sapiens) 6480464 [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ASCL1 mRNA CTD PMID:34480604 L-ascorbic acid 2-phosphate multiple interactions ISO ASCL1 (Homo sapiens) 6480464 [[ascorbate-2-phosphate co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ASCL1 mRNA CTD PMID:34480604 maneb multiple interactions ISO Ascl1 (Mus musculus) 6480464 [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of ASCL1 mRNA CTD PMID:23017109 methylmercury chloride increases expression ISO ASCL1 (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of ASCL1 mRNA CTD PMID:28001369 naphthalene multiple interactions ISO ASCL1 (Homo sapiens) 6480464 ASCL1 protein inhibits the reaction [naphthalene results in decreased expression of CYP2F2 mRNA] more ... CTD PMID:20554700 naphthalene increases expression ISO Ascl1 (Mus musculus) 6480464 naphthalene results in increased expression of ASCL1 protein CTD PMID:20554700 nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of ASCL1 mRNA CTD PMID:28555334 nitrofen decreases expression EXP 6480464 nitrofen results in decreased expression of ASCL1 mRNA CTD PMID:17618886 ochratoxin A decreases expression EXP 6480464 ochratoxin A results in decreased expression of ASCL1 mRNA CTD PMID:21703336 ochratoxin A multiple interactions EXP 6480464 SHH protein modified form inhibits the reaction [ochratoxin A results in decreased expression of ASCL1 mRNA] CTD PMID:21703336 panobinostat multiple interactions ISO ASCL1 (Homo sapiens) 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ASCL1 mRNA CTD PMID:27188386 paraquat multiple interactions ISO Ascl1 (Mus musculus) 6480464 [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of ASCL1 mRNA CTD PMID:23017109 phenylmercury acetate increases expression ISO ASCL1 (Homo sapiens) 6480464 Phenylmercuric Acetate results in increased expression of ASCL1 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO ASCL1 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ASCL1 mRNA CTD PMID:27188386 pirinixic acid multiple interactions ISO ASCL1 (Homo sapiens) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ASCL1 mRNA CTD PMID:19710929 poly(ethylene) decreases expression ISO ASCL1 (Homo sapiens) 6480464 Polyethylene results in decreased expression of ASCL1 mRNA CTD PMID:23203475 propionic acid decreases expression ISO ASCL1 (Homo sapiens) 6480464 propionic acid results in decreased expression of ASCL1 mRNA and propionic acid results in decreased expression of ASCL1 protein CTD PMID:31526819 resveratrol decreases expression ISO ASCL1 (Homo sapiens) 6480464 resveratrol results in decreased expression of ASCL1 mRNA and resveratrol results in decreased expression of ASCL1 protein CTD PMID:21184191 resveratrol increases expression ISO ASCL1 (Homo sapiens) 6480464 resveratrol results in increased expression of ASCL1 mRNA CTD PMID:12002526 sarin increases expression ISO ASCL1 (Homo sapiens) 6480464 Sarin results in increased expression of ASCL1 mRNA CTD PMID:19522546 sarin decreases expression ISO ASCL1 (Homo sapiens) 6480464 Sarin results in decreased expression of ASCL1 mRNA CTD PMID:19522546 SB 431542 multiple interactions ISO ASCL1 (Homo sapiens) 6480464 [LDN 193189 co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 and PMID:34480604 silver atom decreases expression ISO ASCL1 (Homo sapiens) 6480464 Silver results in decreased expression of ASCL1 mRNA CTD PMID:26551752 silver(0) decreases expression ISO ASCL1 (Homo sapiens) 6480464 Silver results in decreased expression of ASCL1 mRNA CTD PMID:26551752 sodium arsenite decreases expression ISO Ascl1 (Mus musculus) 6480464 sodium arsenite results in decreased expression of ASCL1 mRNA CTD PMID:25448440 and PMID:27158593 Soman increases expression EXP 6480464 Soman results in increased expression of ASCL1 mRNA CTD PMID:19281266 tamoxifen multiple interactions EXP 6480464 [bexarotene co-treated with Tamoxifen] results in decreased expression of ASCL1 mRNA CTD PMID:17630414 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of ASCL1 mRNA CTD PMID:31150632 thapsigargin increases expression ISO ASCL1 (Homo sapiens) 6480464 Thapsigargin results in increased expression of ASCL1 mRNA CTD PMID:22378314 titanium dioxide decreases expression ISO Ascl1 (Mus musculus) 6480464 titanium dioxide results in decreased expression of ASCL1 mRNA CTD PMID:23557971 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of ASCL1 mRNA CTD PMID:33387578 trichostatin A increases expression ISO ASCL1 (Homo sapiens) 6480464 trichostatin A results in increased expression of ASCL1 mRNA CTD PMID:24935251 and PMID:26272509 trichostatin A multiple interactions ISO ASCL1 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ASCL1 mRNA CTD PMID:27188386 uranium atom increases expression EXP 6480464 Uranium results in increased expression of ASCL1 mRNA CTD PMID:27639536 valproic acid decreases expression ISO ASCL1 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of ASCL1 mRNA CTD PMID:23179753 more ... valproic acid increases methylation EXP 6480464 Valproic Acid results in increased methylation of ASCL1 promoter CTD PMID:33150595 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of ASCL1 mRNA CTD PMID:33150595 valproic acid multiple interactions ISO ASCL1 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ASCL1 mRNA CTD PMID:27188386 valproic acid increases expression ISO ASCL1 (Homo sapiens) 6480464 Valproic Acid results in increased expression of ASCL1 mRNA CTD PMID:23179753 and PMID:26272509 venlafaxine hydrochloride increases expression EXP 6480464 Venlafaxine Hydrochloride results in increased expression of ASCL1 mRNA CTD PMID:25423262 venlafaxine hydrochloride decreases expression EXP 6480464 Venlafaxine Hydrochloride results in decreased expression of ASCL1 mRNA CTD PMID:25423262 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of ASCL1 mRNA CTD PMID:23869203 vorinostat increases expression ISO ASCL1 (Homo sapiens) 6480464 vorinostat results in increased expression of ASCL1 mRNA CTD PMID:26272509 vorinostat multiple interactions ISO ASCL1 (Homo sapiens) 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ASCL1 mRNA CTD PMID:27188386 XAV939 multiple interactions ISO ASCL1 (Homo sapiens) 6480464 [[ascorbate-2-phosphate co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ASCL1 mRNA and [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ASCL1 mRNA CTD PMID:34480604