Gene: Map2k2 (mitogen activated protein kinase kinase 2) Rattus norvegicus
Symbol: Map2k2
Name: mitogen activated protein kinase kinase 2
Description: ENCODES a protein that exhibits ATP binding; MAP kinase kinase activity; PDZ domain binding (ortholog); INVOLVED IN MAPK cascade; protein phosphorylation; epithelial cell proliferation involved in lung morphogenesis (ortholog); PARTICIPATES IN the extracellular signal-regulated Raf/Mek/Erk signaling pathway; adenosine signaling pathway; ceramide signaling pathway; ASSOCIATED WITH ADENOCARCINOMA OF STOMACH (ortholog); adenoid cystic carcinoma (ortholog); Breast Neoplasms (ortholog); FOUND IN cell cortex; cytosol; cell-cell junction (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol 3-benzoate; 2,4,6-trinitrotoluene
Type: protein-coding
Also known as: dual specificity mitogen-activated protein kinase kinase 2; ERK activator kinase 2; MAP kinase kinase 2; MAPK/ERK kinase 2; MAPKK 2; MEK 2; MEK2; Prkmk2
Homo sapiens (human) : MAP2K2 (mitogen-activated protein kinase kinase 2)  HGNC  Alliance
Mus musculus (house mouse) : Map2k2 (mitogen-activated protein kinase kinase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Map2k2 (mitogen-activated protein kinase kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MAP2K2 (mitogen-activated protein kinase kinase 2)
Canis lupus familiaris (dog) : MAP2K2 (mitogen-activated protein kinase kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Map2k2 (mitogen-activated protein kinase kinase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0711,458,971 - 11,478,520 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0711,626,294 - 11,645,884 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4710,074,654 - 10,094,003 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1710,074,657 - 10,094,003 (-)NCBI
Celera76,778,257 - 6,797,606 (-)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Map2k2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61888
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2018-04-10
Status: ACTIVE