(+)-catechin multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAP2K2 protein] CTD PMID:21882252 1,2-dimethylhydrazine multiple interactions ISO Map2k2 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of MAP2K2 mRNA CTD PMID:22206623 1-(5-isoquinolinesulfonyl)-2-methylpiperazine multiple interactions ISO Map2k2 (Mus musculus) 6480464 [1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine co-treated with TNF protein] results in decreased phosphorylation of MAP2K2 protein CTD PMID:14654170 1-(5-isoquinolinesulfonyl)-2-methylpiperazine decreases phosphorylation ISO Map2k2 (Mus musculus) 6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in decreased phosphorylation of MAP2K2 protein CTD PMID:14654170 1-chloro-2,4-dinitrobenzene affects binding ISO MAP2K2 (Homo sapiens) 6480464 Dinitrochlorobenzene binds to MAP2K2 protein CTD PMID:32991956 17alpha-ethynylestradiol increases expression ISO Map2k2 (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of MAP2K2 mRNA CTD PMID:16174780 and PMID:17942748 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of MAP2K2 mRNA CTD PMID:16174780 and PMID:17351261 17alpha-ethynylestradiol multiple interactions ISO Map2k2 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MAP2K2 mRNA CTD PMID:17942748 17beta-estradiol multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 IGF1R mutant form inhibits the reaction [Estradiol results in increased expression of MAP2K2 mRNA] CTD PMID:23094148 17beta-estradiol increases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 Estradiol results in increased phosphorylation of MAP2K2 protein CTD PMID:27026707 17beta-estradiol increases expression ISO MAP2K2 (Homo sapiens) 6480464 Estradiol results in increased expression of MAP2K2 mRNA CTD PMID:23094148 17beta-estradiol 3-benzoate decreases phosphorylation EXP 6480464 estradiol 3-benzoate results in decreased phosphorylation of MAP2K2 protein CTD PMID:15778002 17beta-hydroxy-5alpha-androstan-3-one multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dihydrotestosterone results in increased phosphorylation of and results in increased activity of MAP2K2 protein] more ... CTD PMID:15466214 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO MAP2K2 (Homo sapiens) 6480464 2 more ... CTD PMID:31675489 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Map2k2 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MAP2K2 mRNA more ... CTD PMID:17942748 and PMID:20450880 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of MAP2K2 mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of MAP2K2 mRNA CTD PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Map2k2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of MAP2K2 mRNA CTD PMID:21570461 2,4,6-tribromophenol decreases expression ISO MAP2K2 (Homo sapiens) 6480464 2 more ... CTD PMID:31675489 2,4,6-trinitrotoluene affects expression EXP 6480464 Trinitrotoluene affects the expression of MAP2K2 mRNA CTD PMID:21346803 2,6-dinitrotoluene affects expression EXP 6480464 2 and 6-dinitrotoluene affects the expression of MAP2K2 mRNA CTD PMID:21346803 2-arachidonoylglycerol multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K2 protein] more ... CTD PMID:12657697 3',5'-cyclic GMP decreases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 Cyclic GMP results in decreased phosphorylation of MAP2K2 protein CTD PMID:18225537 3',5'-cyclic GMP multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 Cyclic GMP affects the reaction [NPPA protein alternative form results in decreased phosphorylation of and results in decreased activity of MAP2K2 protein] CTD PMID:18225537 3,3',4,4'-tetrachlorobiphenyl multiple interactions ISO Map2k2 (Mus musculus) 6480464 3 more ... CTD PMID:19467301 3,3',5,5'-tetrabromobisphenol A decreases expression ISO MAP2K2 (Homo sapiens) 6480464 tetrabromobisphenol A results in decreased expression of MAP2K2 protein CTD PMID:31675489 3,4-methylenedioxymethamphetamine decreases expression ISO Map2k2 (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of MAP2K2 mRNA CTD PMID:19285098 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 bisindolylmaleimide I inhibits the reaction [lead acetate results in increased phosphorylation of and results in increased activity of MAP2K2 protein] CTD PMID:11861786 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO Map2k2 (Mus musculus) 6480464 [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased phosphorylation of MAP2K2 protein and alisol B promotes the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased phosphorylation of MAP2K2 protein] CTD PMID:28051915 3-phenylprop-2-enal decreases expression ISO MAP2K2 (Homo sapiens) 6480464 cinnamaldehyde results in decreased expression of MAP2K2 mRNA CTD PMID:17178418 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of MAP2K2 mRNA CTD PMID:36041667 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAP2K2 protein and Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAP2K2 protein] CTD PMID:21882252 5-(2-methylpiperazine-1-sulfonyl)isoquinoline multiple interactions ISO Map2k2 (Mus musculus) 6480464 [1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine co-treated with TNF protein] results in decreased phosphorylation of MAP2K2 protein CTD PMID:14654170 5-(2-methylpiperazine-1-sulfonyl)isoquinoline decreases phosphorylation ISO Map2k2 (Mus musculus) 6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in decreased phosphorylation of MAP2K2 protein CTD PMID:14654170 5-fluorouracil multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [U 0126 results in decreased activity of MAP2K2 protein] results in increased susceptibility to [Fluorouracil co-treated with Cisplatin] and MAP2K2 protein results in decreased susceptibility to [Cisplatin co-treated with Fluorouracil] CTD PMID:21444628 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects expression EXP 6480464 Omeprazole affects the expression of MAP2K2 mRNA CTD PMID:19483382 6-propyl-2-thiouracil affects expression EXP 6480464 Propylthiouracil affects the expression of MAP2K2 mRNA CTD PMID:19483382 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of MAP2K2 mRNA CTD PMID:30047161 acetylsalicylic acid decreases expression ISO MAP2K2 (Homo sapiens) 6480464 Aspirin results in decreased expression of MAP2K2 mRNA CTD PMID:15928584 acrolein multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with Ozone] results in increased oxidation of MAP2K2 mRNA CTD PMID:32845096 adenosine increases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 Adenosine results in increased phosphorylation of MAP2K2 protein CTD PMID:34070360 afimoxifene decreases response to substance ISO MAP2K2 (Homo sapiens) 6480464 MAP2K2 results in decreased susceptibility to afimoxifene CTD PMID:21233418 aflatoxin B1 decreases methylation ISO MAP2K2 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of MAP2K2 intron CTD PMID:30157460 Alisol B multiple interactions ISO Map2k2 (Mus musculus) 6480464 alisol B promotes the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased phosphorylation of MAP2K2 protein] CTD PMID:28051915 all-trans-retinoic acid increases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 Tretinoin results in increased phosphorylation of MAP2K2 protein CTD PMID:19038232 all-trans-retinoic acid multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arsenic trioxide promotes the reaction [Tretinoin results in increased phosphorylation of and results in increased activity of MAP2K2 protein]] more ... CTD PMID:20615082 all-trans-retinol multiple interactions EXP 6480464 6-hydroxy-2 more ... CTD PMID:16510265 all-trans-retinol increases phosphorylation EXP 6480464 Vitamin A results in increased phosphorylation of MAP2K2 protein CTD PMID:16510265 alpha-mangostin increases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 mangostin analog results in increased phosphorylation of MAP2K2 protein CTD PMID:28722351 amiodarone affects expression EXP 6480464 Amiodarone affects the expression of MAP2K2 mRNA CTD PMID:19483382 amitrole increases expression EXP 6480464 Amitrole results in increased expression of MAP2K2 mRNA CTD PMID:30047161 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of MAP2K2 mRNA CTD PMID:16483693 ammonium chloride increases expression EXP 6480464 Ammonium Chloride results in increased expression of MAP2K2 mRNA and Ammonium Chloride results in increased expression of MAP2K2 protein CTD PMID:12420312 and PMID:16483693 anandamide multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAP2K2 protein] more ... CTD PMID:12657697 Antrocin decreases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 antrocin analog results in decreased phosphorylation of MAP2K2 protein CTD PMID:36565974 aristolochic acid A increases expression ISO MAP2K2 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of MAP2K2 mRNA CTD PMID:33212167 arsenic acid increases activity ISO MAP2K2 (Homo sapiens) 6480464 arsenic acid results in increased activity of MAP2K2 protein CTD PMID:14674888 arsenite(3-) increases activity ISO MAP2K2 (Homo sapiens) 6480464 arsenite results in increased activity of MAP2K2 protein CTD PMID:14674888 arsenous acid multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide promotes the reaction [Tretinoin results in increased phosphorylation of and results in increased activity of MAP2K2 protein]] more ... CTD PMID:20615082 and PMID:26598702 arsenous acid decreases activity ISO MAP2K2 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased activity of MAP2K2 protein CTD PMID:11304686 arsenous acid increases expression ISO MAP2K2 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of MAP2K2 protein CTD PMID:25419056 atrazine affects expression EXP 6480464 Atrazine affects the expression of MAP2K2 mRNA CTD PMID:30580161 benzbromarone affects expression EXP 6480464 Benzbromarone affects the expression of MAP2K2 mRNA CTD PMID:19483382 benzo[a]pyrene multiple interactions ISO Map2k2 (Mus musculus) 6480464 AHR protein affects the reaction [Benzo(a)pyrene affects the expression of MAP2K2 mRNA] and Benzo(a)pyrene promotes the reaction [AHR protein binds to MAP2K2 promoter] CTD PMID:19654925 and PMID:22228805 benzo[a]pyrene affects methylation ISO MAP2K2 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of MAP2K2 intron and Benzo(a)pyrene affects the methylation of MAP2K2 promoter CTD PMID:27901495 and PMID:30157460 benzo[a]pyrene multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAP2K2 protein and Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAP2K2 protein] CTD PMID:21882252 benzo[a]pyrene increases expression ISO Map2k2 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of MAP2K2 mRNA CTD PMID:22228805 bicalutamide multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bicalutamide results in increased phosphorylation of and results in increased activity of MAP2K2 protein] more ... CTD PMID:15466214 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of MAP2K2 mRNA CTD PMID:25181051 bisphenol A increases expression ISO MAP2K2 (Homo sapiens) 6480464 bisphenol A results in increased expression of MAP2K2 mRNA and bisphenol A results in increased expression of MAP2K2 protein CTD PMID:36232920 and PMID:37567409 bisphenol A decreases expression ISO MAP2K2 (Homo sapiens) 6480464 bisphenol A results in decreased expression of MAP2K2 protein CTD PMID:34186270 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of MAP2K2 mRNA CTD PMID:36041667 bisphenol A multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of MAP2K2 gene CTD PMID:31601247 bisphenol A increases expression ISO Map2k2 (Mus musculus) 6480464 bisphenol A results in increased expression of MAP2K2 mRNA CTD PMID:33221593 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of MAP2K2 mRNA CTD PMID:33296240 bisphenol A affects expression ISO MAP2K2 (Homo sapiens) 6480464 bisphenol A affects the expression of MAP2K2 mRNA CTD PMID:30903817 Bisphenol B increases expression ISO MAP2K2 (Homo sapiens) 6480464 bisphenol B results in increased expression of MAP2K2 protein CTD PMID:34186270 bisphenol F multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of MAP2K2 mRNA CTD PMID:36041667 bortezomib decreases expression ISO MAP2K2 (Homo sapiens) 6480464 Bortezomib results in decreased expression of MAP2K2 mRNA CTD PMID:20977926 cadmium atom increases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 Cadmium results in increased phosphorylation of MAP2K2 protein CTD PMID:14499349 cadmium dichloride multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAP2K2 protein] CTD PMID:18703135 cadmium dichloride multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAP2K2 protein] CTD PMID:18703135 cadmium dichloride increases phosphorylation EXP 6480464 Cadmium Chloride results in increased phosphorylation of MAP2K2 protein CTD PMID:18703135 cadmium dichloride increases methylation EXP 6480464 Cadmium Chloride results in increased methylation of MAP2K2 promoter CTD PMID:22457795 cadmium dichloride increases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 Cadmium Chloride results in increased phosphorylation of MAP2K2 protein CTD PMID:18703135 caffeine affects phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 Caffeine affects the phosphorylation of MAP2K2 protein CTD PMID:35688186 calciol increases expression ISO Map2k2 (Mus musculus) 6480464 Cholecalciferol results in increased expression of MAP2K2 mRNA CTD PMID:17170073 calcium atom affects expression EXP 6480464 Calcium affects the expression of MAP2K2 mRNA CTD PMID:15913539 calcium(0) affects expression EXP 6480464 Calcium affects the expression of MAP2K2 mRNA CTD PMID:15913539 cannabidiol increases expression ISO MAP2K2 (Homo sapiens) 6480464 Cannabidiol results in increased expression of MAP2K2 mRNA CTD PMID:32992648 cannabidiol multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [Oxygen co-treated with Ozone co-treated with Cannabidiol] results in decreased expression of MAP2K2 mRNA more ... CTD PMID:32992648 carbon nanotube increases expression ISO Map2k2 (Mus musculus) 6480464 Nanotubes and Carbon analog results in increased expression of MAP2K2 mRNA CTD PMID:25554681 celecoxib decreases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 Celecoxib results in decreased phosphorylation of MAP2K2 protein CTD PMID:16123214 chenodeoxycholic acid multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MAP2K2 mRNA more ... CTD PMID:32152650 and PMID:33819548 chlorpyrifos increases expression ISO Map2k2 (Mus musculus) 6480464 Chlorpyrifos results in increased expression of MAP2K2 mRNA CTD PMID:37019170 cisplatin multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [U 0126 results in decreased activity of MAP2K2 protein] results in increased susceptibility to [Fluorouracil co-treated with Cisplatin] and MAP2K2 protein results in decreased susceptibility to [Cisplatin co-treated with Fluorouracil] CTD PMID:21444628 cisplatin decreases response to substance ISO MAP2K2 (Homo sapiens) 6480464 MAP2K2 results in decreased susceptibility to Cisplatin CTD PMID:21849418 cisplatin increases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 Cisplatin results in increased phosphorylation of MAP2K2 protein CTD PMID:21444628 clofibrate affects expression EXP 6480464 Clofibrate affects the expression of MAP2K2 mRNA CTD PMID:19483382 clozapine increases expression ISO Map2k2 (Mus musculus) 6480464 Clozapine results in increased expression of MAP2K2 mRNA CTD PMID:14647396 clozapine decreases expression EXP 6480464 Clozapine results in decreased expression of MAP2K2 mRNA CTD PMID:15860345 cobalt dichloride increases expression ISO MAP2K2 (Homo sapiens) 6480464 cobaltous chloride results in increased expression of MAP2K2 mRNA CTD PMID:19376846 cocaine multiple interactions ISO Map2k2 (Mus musculus) 6480464 CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAP2K2 protein] CTD PMID:15665076 cocaine increases phosphorylation ISO Map2k2 (Mus musculus) 6480464 Cocaine results in increased phosphorylation of MAP2K2 protein CTD PMID:15665076 colforsin daropate hydrochloride multiple interactions ISO Map2k2 (Mus musculus) 6480464 [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased phosphorylation of MAP2K2 protein and alisol B promotes the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased phosphorylation of MAP2K2 protein] CTD PMID:28051915 copper atom multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which affects the expression of MAP2K2 mRNA CTD PMID:30911355 copper(0) multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which affects the expression of MAP2K2 mRNA CTD PMID:30911355 copper(II) sulfate multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:10564177 cordycepin increases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 cordycepin results in increased phosphorylation of MAP2K2 protein CTD PMID:34070360 crocidolite asbestos increases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 Asbestos and Crocidolite results in increased phosphorylation of MAP2K2 protein CTD PMID:18314537 curcumin multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 MAP2K2 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased expression of RAD51 protein]] more ... CTD PMID:21810436 cyclosporin A increases expression ISO MAP2K2 (Homo sapiens) 6480464 Cyclosporine results in increased expression of MAP2K2 mRNA CTD PMID:32152650 cyclosporin A multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MAP2K2 mRNA CTD PMID:32152650 D-mannitol multiple interactions EXP 6480464 Mannitol inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K2 protein] CTD PMID:16510265 decabromodiphenyl ether decreases expression ISO MAP2K2 (Homo sapiens) 6480464 decabromobiphenyl ether results in decreased expression of MAP2K2 protein CTD PMID:31675489 deguelin decreases expression ISO MAP2K2 (Homo sapiens) 6480464 deguelin results in decreased expression of MAP2K2 protein CTD PMID:19336726 deoxycholic acid multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MAP2K2 mRNA more ... CTD PMID:32152650 and PMID:33819548 diarsenic trioxide multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide promotes the reaction [Tretinoin results in increased phosphorylation of and results in increased activity of MAP2K2 protein]] more ... CTD PMID:20615082 and PMID:26598702 diarsenic trioxide increases expression ISO MAP2K2 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of MAP2K2 protein CTD PMID:25419056 diarsenic trioxide decreases activity ISO MAP2K2 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased activity of MAP2K2 protein CTD PMID:11304686 dibutyl phthalate decreases expression ISO Map2k2 (Mus musculus) 6480464 Dibutyl Phthalate results in decreased expression of MAP2K2 mRNA and Dibutyl Phthalate results in decreased expression of MAP2K2 protein CTD PMID:17361019 and PMID:34864091 dibutyl phthalate multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MAP2K2 protein CTD PMID:30218697 dieldrin multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 Dieldrin results in increased phosphorylation of and results in increased activity of MAP2K2 protein CTD PMID:15888667 dimethyl sulfoxide multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 cucurbitacin IIa inhibits the reaction [Dimethyl Sulfoxide results in increased expression of MAP2K2 mRNA] CTD PMID:31265865 dimethyl sulfoxide increases expression ISO MAP2K2 (Homo sapiens) 6480464 Dimethyl Sulfoxide results in increased expression of MAP2K2 mRNA CTD PMID:31265865 dioxygen multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [Oxygen co-treated with Ozone co-treated with Cannabidiol] results in decreased expression of MAP2K2 mRNA more ... CTD PMID:32992648 disodium selenite increases expression ISO MAP2K2 (Homo sapiens) 6480464 Sodium Selenite results in increased expression of MAP2K2 mRNA CTD PMID:18175754 doxorubicin increases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 Doxorubicin results in increased phosphorylation of MAP2K2 protein CTD PMID:17974986 doxorubicin increases phosphorylation ISO Map2k2 (Mus musculus) 6480464 Doxorubicin results in increased phosphorylation of MAP2K2 protein CTD PMID:17974986 elemental selenium increases expression ISO MAP2K2 (Homo sapiens) 6480464 Selenium results in increased expression of MAP2K2 mRNA CTD PMID:19244175 emodin multiple interactions EXP 6480464 Emodin inhibits the reaction [PDGFB protein results in increased phosphorylation of MAP2K2 protein] CTD PMID:15288473 endosulfan multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 Endosulfan results in increased phosphorylation of and results in increased activity of MAP2K2 protein CTD PMID:15888667 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of MAP2K2 mRNA CTD PMID:31464424 epoxiconazole decreases expression ISO Map2k2 (Mus musculus) 6480464 epoxiconazole results in decreased expression of MAP2K2 mRNA CTD PMID:35436446 ethanol increases expression EXP 6480464 Ethanol results in increased expression of MAP2K2 mRNA CTD PMID:20655511 fenthion decreases expression ISO Map2k2 (Mus musculus) 6480464 Fenthion results in decreased expression of MAP2K2 mRNA CTD PMID:34813904 finasteride increases expression EXP 6480464 Finasteride results in increased expression of MAP2K2 mRNA CTD PMID:24136188 fipronil decreases activity ISO Map2k2 (Mus musculus) 6480464 fipronil results in decreased activity of MAP2K2 protein CTD PMID:21167920 fipronil increases expression EXP 6480464 fipronil results in increased expression of MAP2K2 mRNA CTD PMID:34044035 flutamide increases expression EXP 6480464 Flutamide results in increased expression of MAP2K2 mRNA CTD PMID:24136188 folic acid multiple interactions ISO Map2k2 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of MAP2K2 mRNA CTD PMID:22206623 FR900359 decreases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 FR900359 results in decreased phosphorylation of MAP2K2 protein CTD PMID:37730182 fulvestrant multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of MAP2K2 gene CTD PMID:31601247 gamma-hexachlorocyclohexane multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 Hexachlorocyclohexane results in increased phosphorylation of and results in increased activity of MAP2K2 protein CTD PMID:15888667 geldanamycin decreases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 geldanamycin results in decreased phosphorylation of MAP2K2 protein CTD PMID:19167484 genistein decreases phosphorylation EXP 6480464 Genistein results in decreased phosphorylation of MAP2K2 protein CTD PMID:15781664 genistein increases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 Genistein results in increased phosphorylation of MAP2K2 protein CTD PMID:19038232 glycochenodeoxycholic acid multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MAP2K2 mRNA more ... CTD PMID:32152650 and PMID:33819548 glycocholic acid multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MAP2K2 mRNA more ... CTD PMID:32152650 and PMID:33819548 glycodeoxycholic acid multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MAP2K2 mRNA more ... CTD PMID:32152650 and PMID:33819548 haloperidol decreases expression EXP 6480464 Haloperidol results in decreased expression of MAP2K2 mRNA CTD PMID:15860345 haloperidol increases expression ISO Map2k2 (Mus musculus) 6480464 Haloperidol results in increased expression of MAP2K2 mRNA CTD PMID:14647396 heparin multiple interactions EXP 6480464 Heparin inhibits the reaction [FGF1 protein results in increased phosphorylation of MAP2K2 protein] and Heparin inhibits the reaction [FGF2 protein results in increased phosphorylation of MAP2K2 protein] CTD PMID:14966081 heptachlor multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 Heptachlor results in increased phosphorylation of and results in increased activity of MAP2K2 protein CTD PMID:15888667 hyaluronic acid increases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 Hyaluronic Acid analog results in increased phosphorylation of MAP2K2 protein CTD PMID:12402308 hydrogen peroxide increases activity ISO MAP2K2 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased activity of MAP2K2 protein CTD PMID:19038233 ionomycin multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of MAP2K2 mRNA and pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of MAP2K2 mRNA] CTD PMID:15477007 ivermectin decreases expression ISO MAP2K2 (Homo sapiens) 6480464 Ivermectin results in decreased expression of MAP2K2 protein CTD PMID:32959892 ketamine multiple interactions ISO Map2k2 (Mus musculus) 6480464 Ketamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAP2K2 protein] CTD PMID:19540866 L-ethionine affects expression EXP 6480464 Ethionine affects the expression of MAP2K2 mRNA CTD PMID:19483382 lead diacetate multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 bisindolylmaleimide I inhibits the reaction [lead acetate results in increased phosphorylation of and results in increased activity of MAP2K2 protein] more ... CTD PMID:11861786 lead(0) increases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 Lead results in increased phosphorylation of MAP2K2 protein CTD PMID:19133285 letrozole increases expression ISO Map2k2 (Mus musculus) 6480464 letrozole results in increased expression of MAP2K2 protein CTD PMID:15967659 lipopolysaccharide increases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 Lipopolysaccharides results in increased phosphorylation of MAP2K2 protein CTD PMID:19010997 lipopolysaccharide multiple interactions EXP 6480464 rosiglitazone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAP2K2 protein] CTD PMID:21247645 lipopolysaccharide increases phosphorylation EXP 6480464 Lipopolysaccharides results in increased phosphorylation of MAP2K2 protein CTD PMID:21247645 lipopolysaccharide multiple interactions ISO Map2k2 (Mus musculus) 6480464 [Lipopolysaccharides co-treated with IFNG protein] results in increased phosphorylation of MAP2K2 protein more ... CTD PMID:19540866 and PMID:23362215 lipoteichoic acid increases phosphorylation ISO Map2k2 (Mus musculus) 6480464 lipoteichoic acid results in increased phosphorylation of MAP2K2 protein CTD PMID:19573522 lipoteichoic acid multiple interactions ISO Map2k2 (Mus musculus) 6480464 Propofol inhibits the reaction [lipoteichoic acid results in increased phosphorylation of MAP2K2 protein] CTD PMID:19573522 lycopene decreases expression ISO MAP2K2 (Homo sapiens) 6480464 lycopene results in decreased expression of MAP2K2 protein CTD PMID:17337101 mercury atom increases expression ISO MAP2K2 (Homo sapiens) 6480464 Mercury results in increased expression of MAP2K2 mRNA CTD PMID:16823088 mercury(0) increases expression ISO MAP2K2 (Homo sapiens) 6480464 Mercury results in increased expression of MAP2K2 mRNA CTD PMID:16823088 methimazole increases expression EXP 6480464 Methimazole results in increased expression of MAP2K2 mRNA CTD PMID:30047161 methotrexate affects response to substance ISO MAP2K2 (Homo sapiens) 6480464 MAP2K2 protein affects the susceptibility to Methotrexate CTD PMID:16217747 mitomycin C multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 MAP2K2 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased expression of RAD51 protein]] more ... CTD PMID:21810436 monosodium L-glutamate decreases expression EXP 6480464 Sodium Glutamate results in decreased expression of MAP2K2 mRNA CTD PMID:28954212 N-acetyl-L-cysteine multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAP2K2 protein] CTD PMID:18703135 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAP2K2 protein] CTD PMID:18703135 N-nitrosodiethylamine affects phosphorylation ISO Map2k2 (Mus musculus) 6480464 Diethylnitrosamine affects the phosphorylation of MAP2K2 protein CTD PMID:24535843 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of MAP2K2 mRNA CTD PMID:24136188 ochratoxin A increases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 ochratoxin A results in increased phosphorylation of MAP2K2 protein CTD PMID:25002221 omeprazole affects expression EXP 6480464 Omeprazole affects the expression of MAP2K2 mRNA CTD PMID:19483382 ozone multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with Ozone] results in increased oxidation of MAP2K2 mRNA more ... CTD PMID:32845096 more ... paracetamol affects expression ISO Map2k2 (Mus musculus) 6480464 Acetaminophen affects the expression of MAP2K2 mRNA CTD PMID:17562736 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of MAP2K2 mRNA CTD PMID:33387578 paracetamol multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in increased expression of MAP2K2 mRNA CTD PMID:33819548 PD 0325901 multiple interactions EXP 6480464 mirdametinib inhibits the reaction [polyphyllin I inhibits the reaction [Dietary Fats results in decreased expression of MAP2K2 protein]] CTD PMID:36120828 perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of MAP2K2 mRNA CTD PMID:20136073 PhIP increases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased phosphorylation of MAP2K2 protein CTD PMID:22307971 phlorizin increases expression ISO Map2k2 (Mus musculus) 6480464 Phlorhizin results in increased expression of MAP2K2 mRNA CTD PMID:22538082 phorbol 13-acetate 12-myristate multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MAP2K2 protein more ... CTD PMID:11861786 more ... phorbol 13-acetate 12-myristate increases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of MAP2K2 protein CTD PMID:20479004 pirinixic acid multiple interactions ISO Map2k2 (Mus musculus) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of MAP2K2 mRNA CTD PMID:19710929 pirinixic acid increases expression ISO Map2k2 (Mus musculus) 6480464 pirinixic acid results in increased expression of MAP2K2 mRNA CTD PMID:23811191 pirinixic acid affects expression EXP 6480464 pirinixic acid affects the expression of MAP2K2 mRNA CTD PMID:19483382 pregnenolone 16alpha-carbonitrile decreases expression EXP 6480464 Pregnenolone Carbonitrile results in decreased expression of MAP2K2 mRNA CTD PMID:19162173 propiconazole increases expression EXP 6480464 propiconazole results in increased expression of MAP2K2 mRNA CTD PMID:30047161 propofol multiple interactions ISO Map2k2 (Mus musculus) 6480464 Propofol inhibits the reaction [lipoteichoic acid results in increased phosphorylation of MAP2K2 protein] CTD PMID:19573522 prostaglandin F2alpha increases phosphorylation ISO Map2k2 (Mus musculus) 6480464 Dinoprost results in increased phosphorylation of MAP2K2 protein CTD PMID:24333336 prostaglandin F2alpha multiple interactions ISO Map2k2 (Mus musculus) 6480464 Resveratrol inhibits the reaction [Dinoprost results in increased phosphorylation of MAP2K2 protein] and SRT1720 inhibits the reaction [Dinoprost results in increased phosphorylation of MAP2K2 protein] CTD PMID:24333336 pyocyanine increases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 Pyocyanine results in increased phosphorylation of MAP2K2 protein CTD PMID:24015256 pyrrolidine dithiocarbamate multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of MAP2K2 mRNA] CTD PMID:15477007 quercetin decreases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 Quercetin results in decreased phosphorylation of MAP2K2 protein CTD PMID:35688186 resveratrol increases expression ISO Map2k2 (Mus musculus) 6480464 resveratrol results in increased expression of MAP2K2 protein CTD PMID:25505154 resveratrol multiple interactions ISO Map2k2 (Mus musculus) 6480464 resveratrol inhibits the reaction [Dinoprost results in increased phosphorylation of MAP2K2 protein] CTD PMID:24333336 sarin decreases expression ISO MAP2K2 (Homo sapiens) 6480464 Sarin results in decreased expression of MAP2K2 mRNA CTD PMID:19522546 SB 431542 multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of MAP2K2 protein CTD PMID:37664457 SCH772984 increases phosphorylation EXP 6480464 SCH772984 results in increased phosphorylation of MAP2K2 protein CTD PMID:28087833 selenium atom increases expression ISO MAP2K2 (Homo sapiens) 6480464 Selenium results in increased expression of MAP2K2 mRNA CTD PMID:19244175 silver atom decreases expression ISO Map2k2 (Mus musculus) 6480464 Silver results in decreased expression of MAP2K2 mRNA CTD PMID:27131904 silver(0) decreases expression ISO Map2k2 (Mus musculus) 6480464 Silver results in decreased expression of MAP2K2 mRNA CTD PMID:27131904 sirolimus multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [7-hydroxystaurosporine co-treated with Sirolimus] results in decreased phosphorylation of MAP2K2 protein CTD PMID:15767555 sodium arsenite multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:10564177 and PMID:11943669 sodium arsenite increases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 sodium arsenite results in increased phosphorylation of MAP2K2 protein CTD PMID:11943669 sodium arsenite increases expression ISO MAP2K2 (Homo sapiens) 6480464 sodium arsenite results in increased expression of MAP2K2 mRNA CTD PMID:24431212 sodium arsenite affects expression ISO MAP2K2 (Homo sapiens) 6480464 sodium arsenite affects the expression of MAP2K2 protein modified form CTD PMID:17384772 sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of MAP2K2 mRNA CTD PMID:12325037 sodium fluoride increases phosphorylation EXP 6480464 Sodium Fluoride results in increased phosphorylation of MAP2K2 protein CTD PMID:19900517 sorafenib multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [sorafenib co-treated with PI103] inhibits the reaction [EGF protein results in increased phosphorylation of MAP2K2 protein] and sorafenib inhibits the reaction [EGF protein results in increased phosphorylation of MAP2K2 protein] CTD PMID:21187475 sorafenib decreases phosphorylation EXP 6480464 sorafenib results in decreased phosphorylation of MAP2K2 protein CTD PMID:17341847 sorafenib decreases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 sorafenib results in decreased phosphorylation of MAP2K2 protein CTD PMID:17341847 and PMID:18200035 sulfadimethoxine increases expression EXP 6480464 Sulfadimethoxine results in increased expression of MAP2K2 mRNA CTD PMID:30047161 tartrazine multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of MAP2K2 mRNA CTD PMID:33819548 tetrahydropalmatine decreases expression ISO MAP2K2 (Homo sapiens) 6480464 tetrahydropalmatine results in decreased expression of MAP2K2 protein CTD PMID:20109541 thimerosal decreases expression ISO MAP2K2 (Homo sapiens) 6480464 Thimerosal results in decreased expression of MAP2K2 mRNA CTD PMID:27188386 thioacetamide affects expression EXP 6480464 Thioacetamide affects the expression of MAP2K2 mRNA CTD PMID:19483382 titanium dioxide increases phosphorylation ISO Map2k2 (Mus musculus) 6480464 titanium dioxide analog results in increased phosphorylation of MAP2K2 protein CTD PMID:25111187 toluene affects expression EXP 6480464 Toluene affects the expression of MAP2K2 mRNA CTD PMID:21827849 trichloroethene increases expression ISO Map2k2 (Mus musculus) 6480464 Trichloroethylene results in increased expression of MAP2K2 mRNA CTD PMID:19448997 triptonide increases expression ISO Map2k2 (Mus musculus) 6480464 triptonide results in increased expression of MAP2K2 mRNA CTD PMID:33045310 tyrphostin AG 1478 multiple interactions EXP 6480464 RTKI cpd inhibits the reaction [Oleylethanolamide results in increased phosphorylation of MAP2K2 protein] CTD PMID:16269455 urethane increases expression ISO MAP2K2 (Homo sapiens) 6480464 Urethane results in increased expression of MAP2K2 mRNA CTD PMID:28818685 valdecoxib increases expression EXP 6480464 valdecoxib results in increased expression of MAP2K2 mRNA CTD PMID:24136188 valproic acid affects expression ISO Map2k2 (Mus musculus) 6480464 Valproic Acid affects the expression of MAP2K2 mRNA CTD PMID:17292431 vanadyl sulfate multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:10564177 and PMID:11943669 vanadyl sulfate increases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 vanadyl sulfate results in increased phosphorylation of MAP2K2 protein CTD PMID:11943669 vanillin decreases expression ISO MAP2K2 (Homo sapiens) 6480464 vanillin results in decreased expression of MAP2K2 mRNA CTD PMID:17178418 wogonin multiple interactions ISO Map2k2 (Mus musculus) 6480464 wogonin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased phosphorylation of MAP2K2 protein] CTD PMID:23362215 zinc sulfate multiple interactions ISO MAP2K2 (Homo sapiens) 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:10564177 and PMID:11943669 zinc sulfate increases phosphorylation ISO MAP2K2 (Homo sapiens) 6480464 Zinc Sulfate results in increased phosphorylation of MAP2K2 protein CTD PMID:11943669