(+)-catechin multiple interactions ISO RGD:1343460 6480464 Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAP2K2 protein] CTD PMID:21882252 1-(5-isoquinolinesulfonyl)-2-methylpiperazine multiple interactions ISO RGD:62181 6480464 [1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine co-treated with TNF protein] results in decreased phosphorylation of MAP2K2 protein CTD PMID:14654170 1-(5-isoquinolinesulfonyl)-2-methylpiperazine decreases phosphorylation ISO RGD:62181 6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in decreased phosphorylation of MAP2K2 protein CTD PMID:14654170 17alpha-ethynylestradiol increases expression ISO RGD:62181 6480464 Ethinyl Estradiol results in increased expression of MAP2K2 mRNA CTD PMID:16174780 , PMID:17942748 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of MAP2K2 mRNA CTD PMID:16174780 , PMID:17351261 17alpha-ethynylestradiol multiple interactions ISO RGD:62181 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MAP2K2 mRNA CTD PMID:17942748 17beta-estradiol multiple interactions ISO RGD:1343460 6480464 IGF1R mutant form inhibits the reaction [Estradiol results in increased expression of MAP2K2 mRNA] CTD PMID:23094148 17beta-estradiol increases phosphorylation ISO RGD:1343460 6480464 Estradiol results in increased phosphorylation of MAP2K2 protein CTD PMID:27026707 17beta-estradiol increases expression ISO RGD:1343460 6480464 Estradiol results in increased expression of MAP2K2 mRNA CTD PMID:23094148 17beta-estradiol 3-benzoate decreases phosphorylation EXP 6480464 estradiol 3-benzoate results in decreased phosphorylation of MAP2K2 protein CTD PMID:15778002 17beta-hydroxy-5alpha-androstan-3-one multiple interactions ISO RGD:1343460 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dihydrotestosterone results in increased phosphorylation of and results in increased activity of MAP2K2 protein] more ... CTD PMID:15466214 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:62181 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MAP2K2 mRNA more ... CTD PMID:17942748 , PMID:20450880 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:62181 6480464 Tetrachlorodibenzodioxin affects the expression of MAP2K2 mRNA CTD PMID:21570461 2,4,6-trinitrotoluene affects expression EXP 6480464 Trinitrotoluene affects the expression of MAP2K2 mRNA CTD PMID:21346803 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of MAP2K2 mRNA CTD PMID:21346803 2-arachidonoylglycerol multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K2 protein] more ... CTD PMID:12657697 3',5'-cyclic GMP decreases phosphorylation ISO RGD:1343460 6480464 Cyclic GMP results in decreased phosphorylation of MAP2K2 protein CTD PMID:18225537 3',5'-cyclic GMP multiple interactions ISO RGD:1343460 6480464 Cyclic GMP affects the reaction [NPPA protein alternative form results in decreased phosphorylation of and results in decreased activity of MAP2K2 protein] CTD PMID:18225537 3,3',4,4'-tetrachlorobiphenyl multiple interactions ISO RGD:62181 6480464 3 more ... CTD PMID:19467301 3,4-methylenedioxymethamphetamine decreases expression ISO RGD:62181 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of MAP2K2 mRNA CTD PMID:19285098 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO RGD:1343460 6480464 bisindolylmaleimide I inhibits the reaction [lead acetate results in increased phosphorylation of and results in increased activity of MAP2K2 protein] CTD PMID:11861786 3-phenylprop-2-enal decreases expression ISO RGD:1343460 6480464 cinnamic aldehyde results in decreased expression of MAP2K2 mRNA CTD PMID:17178418 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions ISO RGD:1343460 6480464 [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAP2K2 protein, Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAP2K2 protein] CTD PMID:21882252 5-(2-methylpiperazine-1-sulfonyl)isoquinoline multiple interactions ISO RGD:62181 6480464 [1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine co-treated with TNF protein] results in decreased phosphorylation of MAP2K2 protein CTD PMID:14654170 5-(2-methylpiperazine-1-sulfonyl)isoquinoline decreases phosphorylation ISO RGD:62181 6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in decreased phosphorylation of MAP2K2 protein CTD PMID:14654170 5-fluorouracil multiple interactions ISO RGD:1343460 6480464 [U 0126 results in decreased activity of MAP2K2 protein] results in increased susceptibility to [Fluorouracil co-treated with Cisplatin], MAP2K2 protein results in decreased susceptibility to [Cisplatin co-treated with Fluorouracil] CTD PMID:21444628 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects expression EXP 6480464 Omeprazole affects the expression of MAP2K2 mRNA CTD PMID:19483382 6-propyl-2-thiouracil affects expression EXP 6480464 Propylthiouracil affects the expression of MAP2K2 mRNA CTD PMID:19483382 acetylsalicylic acid decreases expression ISO RGD:1343460 6480464 Aspirin results in decreased expression of MAP2K2 mRNA CTD PMID:15928584 afimoxifene decreases response to substance ISO RGD:1343460 6480464 MAP2K2 results in decreased susceptibility to afimoxifene CTD PMID:21233418 aflatoxin B1 decreases methylation ISO RGD:1343460 6480464 Aflatoxin B1 results in decreased methylation of MAP2K2 intron CTD PMID:30157460 all-trans-retinoic acid increases phosphorylation ISO RGD:1343460 6480464 Tretinoin results in increased phosphorylation of MAP2K2 protein CTD PMID:19038232 all-trans-retinoic acid multiple interactions ISO RGD:1343460 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arsenic trioxide promotes the reaction [Tretinoin results in increased phosphorylation of and results in increased activity of MAP2K2 protein]] more ... CTD PMID:20615082 all-trans-retinol multiple interactions EXP 6480464 6-hydroxy-2 more ... CTD PMID:16510265 all-trans-retinol increases phosphorylation EXP 6480464 Vitamin A results in increased phosphorylation of MAP2K2 protein CTD PMID:16510265 alpha-mangostin increases phosphorylation ISO RGD:1343460 6480464 mangostin analog results in increased phosphorylation of MAP2K2 protein CTD PMID:28722351 amiodarone affects expression EXP 6480464 Amiodarone affects the expression of MAP2K2 mRNA CTD PMID:19483382 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of MAP2K2 mRNA CTD PMID:16483693 ammonium chloride increases expression EXP 6480464 Ammonium Chloride results in increased expression of MAP2K2 mRNA, Ammonium Chloride results in increased expression of MAP2K2 protein CTD PMID:12420312 , PMID:16483693 anandamide multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAP2K2 protein] more ... CTD PMID:12657697 arsenic acid increases activity ISO RGD:1343460 6480464 arsenic acid results in increased activity of MAP2K2 protein CTD PMID:14674888 arsenite(3-) increases activity ISO RGD:1343460 6480464 arsenite results in increased activity of MAP2K2 protein CTD PMID:14674888 arsenous acid multiple interactions ISO RGD:1343460 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide promotes the reaction [Tretinoin results in increased phosphorylation of and results in increased activity of MAP2K2 protein]] more ... CTD PMID:20615082 , PMID:26598702 arsenous acid decreases activity ISO RGD:1343460 6480464 Arsenic Trioxide results in decreased activity of MAP2K2 protein CTD PMID:11304686 arsenous acid increases expression ISO RGD:1343460 6480464 Arsenic Trioxide results in increased expression of MAP2K2 protein CTD PMID:25419056 benzbromarone affects expression EXP 6480464 Benzbromarone affects the expression of MAP2K2 mRNA CTD PMID:19483382 benzo[a]pyrene multiple interactions ISO RGD:62181 6480464 AHR protein affects the reaction [Benzo(a)pyrene affects the expression of MAP2K2 mRNA], Benzo(a)pyrene promotes the reaction [AHR protein binds to MAP2K2 promoter] CTD PMID:19654925 , PMID:22228805 benzo[a]pyrene affects methylation ISO RGD:1343460 6480464 Benzo(a)pyrene affects the methylation of MAP2K2 intron CTD PMID:30157460 benzo[a]pyrene multiple interactions ISO RGD:1343460 6480464 [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAP2K2 protein, Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAP2K2 protein] CTD PMID:21882252 benzo[a]pyrene increases expression ISO RGD:62181 6480464 Benzo(a)pyrene results in increased expression of MAP2K2 mRNA CTD PMID:22228805 bicalutamide multiple interactions ISO RGD:1343460 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bicalutamide results in increased phosphorylation of and results in increased activity of MAP2K2 protein] more ... CTD PMID:15466214 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of MAP2K2 mRNA CTD PMID:25181051 bisphenol A affects expression ISO RGD:1343460 6480464 bisphenol A affects the expression of MAP2K2 mRNA CTD PMID:30903817 bortezomib decreases expression ISO RGD:1343460 6480464 Bortezomib results in decreased expression of MAP2K2 mRNA CTD PMID:20977926 cadmium atom increases phosphorylation ISO RGD:1343460 6480464 Cadmium results in increased phosphorylation of MAP2K2 protein CTD PMID:14499349 cadmium dichloride multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAP2K2 protein] CTD PMID:18703135 cadmium dichloride multiple interactions ISO RGD:1343460 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAP2K2 protein] CTD PMID:18703135 cadmium dichloride increases phosphorylation EXP 6480464 Cadmium Chloride results in increased phosphorylation of MAP2K2 protein CTD PMID:18703135 cadmium dichloride increases methylation EXP 6480464 Cadmium Chloride results in increased methylation of MAP2K2 promoter CTD PMID:22457795 cadmium dichloride increases phosphorylation ISO RGD:1343460 6480464 Cadmium Chloride results in increased phosphorylation of MAP2K2 protein CTD PMID:18703135 calciol increases expression ISO RGD:62181 6480464 Cholecalciferol results in increased expression of MAP2K2 mRNA CTD PMID:17170073 calcium atom affects expression EXP 6480464 Calcium affects the expression of MAP2K2 mRNA CTD PMID:15913539 calcium(0) affects expression EXP 6480464 Calcium affects the expression of MAP2K2 mRNA CTD PMID:15913539 carbon nanotube increases expression ISO RGD:62181 6480464 Nanotubes, Carbon analog results in increased expression of MAP2K2 mRNA CTD PMID:25554681 celecoxib decreases phosphorylation ISO RGD:1343460 6480464 Celecoxib results in decreased phosphorylation of MAP2K2 protein CTD PMID:16123214 cisplatin multiple interactions ISO RGD:1343460 6480464 [U 0126 results in decreased activity of MAP2K2 protein] results in increased susceptibility to [Fluorouracil co-treated with Cisplatin], MAP2K2 protein results in decreased susceptibility to [Cisplatin co-treated with Fluorouracil] CTD PMID:21444628 cisplatin decreases response to substance ISO RGD:1343460 6480464 MAP2K2 results in decreased susceptibility to Cisplatin CTD PMID:21849418 cisplatin increases phosphorylation ISO RGD:1343460 6480464 Cisplatin results in increased phosphorylation of MAP2K2 protein CTD PMID:21444628 clofibrate affects expression EXP 6480464 Clofibrate affects the expression of MAP2K2 mRNA CTD PMID:19483382 clozapine increases expression ISO RGD:62181 6480464 Clozapine results in increased expression of MAP2K2 mRNA CTD PMID:14647396 clozapine decreases expression EXP 6480464 Clozapine results in decreased expression of MAP2K2 mRNA CTD PMID:15860345 cobalt dichloride increases expression ISO RGD:1343460 6480464 cobaltous chloride results in increased expression of MAP2K2 mRNA CTD PMID:19376846 cocaine multiple interactions ISO RGD:62181 6480464 CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAP2K2 protein] CTD PMID:15665076 cocaine increases phosphorylation ISO RGD:62181 6480464 Cocaine results in increased phosphorylation of MAP2K2 protein CTD PMID:15665076 copper(II) sulfate multiple interactions ISO RGD:1343460 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:10564177 crocidolite asbestos increases phosphorylation ISO RGD:1343460 6480464 Asbestos, Crocidolite results in increased phosphorylation of MAP2K2 protein CTD PMID:18314537 curcumin multiple interactions ISO RGD:1343460 6480464 MAP2K2 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased expression of RAD51 protein]] more ... CTD PMID:21810436 D-mannitol multiple interactions EXP 6480464 Mannitol inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K2 protein] CTD PMID:16510265 Deguelin decreases expression ISO RGD:1343460 6480464 deguelin results in decreased expression of MAP2K2 protein CTD PMID:19336726 diarsenic trioxide multiple interactions ISO RGD:1343460 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide promotes the reaction [Tretinoin results in increased phosphorylation of and results in increased activity of MAP2K2 protein]] more ... CTD PMID:20615082 , PMID:26598702 diarsenic trioxide increases expression ISO RGD:1343460 6480464 Arsenic Trioxide results in increased expression of MAP2K2 protein CTD PMID:25419056 diarsenic trioxide decreases activity ISO RGD:1343460 6480464 Arsenic Trioxide results in decreased activity of MAP2K2 protein CTD PMID:11304686 dibutyl phthalate decreases expression ISO RGD:62181 6480464 Dibutyl Phthalate results in decreased expression of MAP2K2 mRNA CTD PMID:17361019 dibutyl phthalate multiple interactions ISO RGD:1343460 6480464 [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MAP2K2 protein CTD PMID:30218697 dieldrin multiple interactions ISO RGD:1343460 6480464 Dieldrin results in increased phosphorylation of and results in increased activity of MAP2K2 protein CTD PMID:15888667 dimethyl sulfoxide multiple interactions ISO RGD:1343460 6480464 cucurbitacin IIa inhibits the reaction [Dimethyl Sulfoxide results in increased expression of MAP2K2 mRNA] CTD PMID:31265865 dimethyl sulfoxide increases expression ISO RGD:1343460 6480464 Dimethyl Sulfoxide results in increased expression of MAP2K2 mRNA CTD PMID:31265865 disodium selenite increases expression ISO RGD:1343460 6480464 Sodium Selenite results in increased expression of MAP2K2 mRNA CTD PMID:18175754 doxorubicin increases phosphorylation ISO RGD:1343460 6480464 Doxorubicin results in increased phosphorylation of MAP2K2 protein CTD PMID:17974986 doxorubicin increases phosphorylation ISO RGD:62181 6480464 Doxorubicin results in increased phosphorylation of MAP2K2 protein CTD PMID:17974986 elemental selenium increases expression ISO RGD:1343460 6480464 Selenium results in increased expression of MAP2K2 mRNA CTD PMID:19244175 emodin multiple interactions EXP 6480464 Emodin inhibits the reaction [PDGFB protein results in increased phosphorylation of MAP2K2 protein] CTD PMID:15288473 endosulfan multiple interactions ISO RGD:1343460 6480464 Endosulfan results in increased phosphorylation of and results in increased activity of MAP2K2 protein CTD PMID:15888667 ethanol increases expression EXP 6480464 Ethanol results in increased expression of MAP2K2 mRNA CTD PMID:20655511 finasteride increases expression EXP 6480464 Finasteride results in increased expression of MAP2K2 mRNA CTD PMID:24136188 fipronil decreases activity ISO RGD:62181 6480464 fipronil results in decreased activity of MAP2K2 protein CTD PMID:21167920 flutamide increases expression EXP 6480464 Flutamide results in increased expression of MAP2K2 mRNA CTD PMID:24136188 gamma-hexachlorocyclohexane multiple interactions ISO RGD:1343460 6480464 Hexachlorocyclohexane results in increased phosphorylation of and results in increased activity of MAP2K2 protein CTD PMID:15888667 geldanamycin decreases phosphorylation ISO RGD:1343460 6480464 geldanamycin results in decreased phosphorylation of MAP2K2 protein CTD PMID:19167484 genistein decreases phosphorylation EXP 6480464 Genistein results in decreased phosphorylation of MAP2K2 protein CTD PMID:15781664 genistein increases phosphorylation ISO RGD:1343460 6480464 Genistein results in increased phosphorylation of MAP2K2 protein CTD PMID:19038232 haloperidol decreases expression EXP 6480464 Haloperidol results in decreased expression of MAP2K2 mRNA CTD PMID:15860345 haloperidol increases expression ISO RGD:62181 6480464 Haloperidol results in increased expression of MAP2K2 mRNA CTD PMID:14647396 heparin multiple interactions EXP 6480464 Heparin inhibits the reaction [FGF1 protein results in increased phosphorylation of MAP2K2 protein], Heparin inhibits the reaction [FGF2 protein results in increased phosphorylation of MAP2K2 protein] CTD PMID:14966081 heptachlor multiple interactions ISO RGD:1343460 6480464 Heptachlor results in increased phosphorylation of and results in increased activity of MAP2K2 protein CTD PMID:15888667 hyaluronic acid increases phosphorylation ISO RGD:1343460 6480464 Hyaluronic Acid analog results in increased phosphorylation of MAP2K2 protein CTD PMID:12402308 hydrogen peroxide increases activity ISO RGD:1343460 6480464 Hydrogen Peroxide results in increased activity of MAP2K2 protein CTD PMID:19038233 ionomycin multiple interactions ISO RGD:1343460 6480464 [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of MAP2K2 mRNA, pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of MAP2K2 mRNA] CTD PMID:15477007 ketamine multiple interactions ISO RGD:62181 6480464 Ketamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAP2K2 protein] CTD PMID:19540866 L-ethionine affects expression EXP 6480464 Ethionine affects the expression of MAP2K2 mRNA CTD PMID:19483382 lead diacetate multiple interactions ISO RGD:1343460 6480464 bisindolylmaleimide I inhibits the reaction [lead acetate results in increased phosphorylation of and results in increased activity of MAP2K2 protein] more ... CTD PMID:11861786 lead(0) increases phosphorylation ISO RGD:1343460 6480464 Lead results in increased phosphorylation of MAP2K2 protein CTD PMID:19133285 lead(2+) increases phosphorylation ISO RGD:1343460 6480464 Lead results in increased phosphorylation of MAP2K2 protein CTD PMID:19133285 letrozole increases expression ISO RGD:62181 6480464 letrozole results in increased expression of MAP2K2 protein CTD PMID:15967659 lipopolysaccharide increases phosphorylation ISO RGD:1343460 6480464 Lipopolysaccharides results in increased phosphorylation of MAP2K2 protein CTD PMID:19010997 lipopolysaccharide multiple interactions EXP 6480464 rosiglitazone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAP2K2 protein] CTD PMID:21247645 lipopolysaccharide increases phosphorylation EXP 6480464 Lipopolysaccharides results in increased phosphorylation of MAP2K2 protein CTD PMID:21247645 lipopolysaccharide multiple interactions ISO RGD:62181 6480464 [Lipopolysaccharides co-treated with IFNG protein] results in increased phosphorylation of MAP2K2 protein more ... CTD PMID:19540866 , PMID:23362215 lipoteichoic acid increases phosphorylation ISO RGD:62181 6480464 lipoteichoic acid results in increased phosphorylation of MAP2K2 protein CTD PMID:19573522 lipoteichoic acid multiple interactions ISO RGD:62181 6480464 Propofol inhibits the reaction [lipoteichoic acid results in increased phosphorylation of MAP2K2 protein] CTD PMID:19573522 lycopene decreases expression ISO RGD:1343460 6480464 lycopene results in decreased expression of MAP2K2 protein CTD PMID:17337101 mercury atom increases expression ISO RGD:1343460 6480464 Mercury results in increased expression of MAP2K2 mRNA CTD PMID:16823088 mercury(0) increases expression ISO RGD:1343460 6480464 Mercury results in increased expression of MAP2K2 mRNA CTD PMID:16823088 methotrexate affects response to substance ISO RGD:1343460 6480464 MAP2K2 protein affects the susceptibility to Methotrexate CTD PMID:16217747 mitomycin C multiple interactions ISO RGD:1343460 6480464 MAP2K2 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased expression of RAD51 protein]] more ... CTD PMID:21810436 monosodium L-glutamate decreases expression EXP 6480464 Sodium Glutamate results in decreased expression of MAP2K2 mRNA CTD PMID:28954212 N-acetyl-L-cysteine multiple interactions ISO RGD:1343460 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAP2K2 protein] CTD PMID:18703135 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAP2K2 protein] CTD PMID:18703135 N-nitrosodiethylamine affects phosphorylation ISO RGD:62181 6480464 Diethylnitrosamine affects the phosphorylation of MAP2K2 protein CTD PMID:24535843 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of MAP2K2 mRNA CTD PMID:24136188 ochratoxin A increases phosphorylation ISO RGD:1343460 6480464 ochratoxin A results in increased phosphorylation of MAP2K2 protein CTD PMID:25002221 omeprazole affects expression EXP 6480464 Omeprazole affects the expression of MAP2K2 mRNA CTD PMID:19483382 paracetamol affects expression ISO RGD:62181 6480464 Acetaminophen affects the expression of MAP2K2 mRNA CTD PMID:17562736 perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of MAP2K2 mRNA CTD PMID:20136073 PhIP increases phosphorylation ISO RGD:1343460 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased phosphorylation of MAP2K2 protein CTD PMID:22307971 phlorizin increases expression ISO RGD:62181 6480464 Phlorhizin results in increased expression of MAP2K2 mRNA CTD PMID:22538082 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:1343460 6480464 [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MAP2K2 protein more ... CTD PMID:11861786 more ... phorbol 13-acetate 12-myristate increases phosphorylation ISO RGD:1343460 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of MAP2K2 protein CTD PMID:20479004 pirinixic acid multiple interactions ISO RGD:62181 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of MAP2K2 mRNA CTD PMID:19710929 pirinixic acid increases expression ISO RGD:62181 6480464 pirinixic acid results in increased expression of MAP2K2 mRNA CTD PMID:23811191 pirinixic acid affects expression EXP 6480464 pirinixic acid affects the expression of MAP2K2 mRNA CTD PMID:19483382 pregnenolone 16alpha-carbonitrile decreases expression EXP 6480464 Pregnenolone Carbonitrile results in decreased expression of MAP2K2 mRNA CTD PMID:19162173 propofol multiple interactions ISO RGD:62181 6480464 Propofol inhibits the reaction [lipoteichoic acid results in increased phosphorylation of MAP2K2 protein] CTD PMID:19573522 prostaglandin F2alpha increases phosphorylation ISO RGD:62181 6480464 Dinoprost results in increased phosphorylation of MAP2K2 protein CTD PMID:24333336 prostaglandin F2alpha multiple interactions ISO RGD:62181 6480464 Resveratrol inhibits the reaction [Dinoprost results in increased phosphorylation of MAP2K2 protein], SRT1720 inhibits the reaction [Dinoprost results in increased phosphorylation of MAP2K2 protein] CTD PMID:24333336 pyocyanine increases phosphorylation ISO RGD:1343460 6480464 Pyocyanine results in increased phosphorylation of MAP2K2 protein CTD PMID:24015256 pyrrolidine dithiocarbamate multiple interactions ISO RGD:1343460 6480464 pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of MAP2K2 mRNA] CTD PMID:15477007 resveratrol increases expression ISO RGD:62181 6480464 resveratrol results in increased expression of MAP2K2 protein CTD PMID:25505154 resveratrol multiple interactions ISO RGD:62181 6480464 resveratrol inhibits the reaction [Dinoprost results in increased phosphorylation of MAP2K2 protein] CTD PMID:24333336 sarin decreases expression ISO RGD:1343460 6480464 Sarin results in decreased expression of MAP2K2 mRNA CTD PMID:19522546 selenium atom increases expression ISO RGD:1343460 6480464 Selenium results in increased expression of MAP2K2 mRNA CTD PMID:19244175 silver atom decreases expression ISO RGD:62181 6480464 Silver results in decreased expression of MAP2K2 mRNA CTD PMID:27131904 silver(0) decreases expression ISO RGD:62181 6480464 Silver results in decreased expression of MAP2K2 mRNA CTD PMID:27131904 sirolimus multiple interactions ISO RGD:1343460 6480464 [7-hydroxystaurosporine co-treated with Sirolimus] results in decreased phosphorylation of MAP2K2 protein CTD PMID:15767555 sodium arsenite multiple interactions ISO RGD:1343460 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:10564177 , PMID:11943669 sodium arsenite increases phosphorylation ISO RGD:1343460 6480464 sodium arsenite results in increased phosphorylation of MAP2K2 protein CTD PMID:11943669 sodium arsenite increases expression ISO RGD:1343460 6480464 sodium arsenite results in increased expression of MAP2K2 mRNA CTD PMID:24431212 sodium arsenite affects expression ISO RGD:1343460 6480464 sodium arsenite affects the expression of MAP2K2 protein modified form CTD PMID:17384772 sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of MAP2K2 mRNA CTD PMID:12325037 sodium fluoride increases phosphorylation EXP 6480464 Sodium Fluoride results in increased phosphorylation of MAP2K2 protein CTD PMID:19900517 sorafenib multiple interactions ISO RGD:1343460 6480464 [sorafenib co-treated with PI103] inhibits the reaction [EGF protein results in increased phosphorylation of MAP2K2 protein], sorafenib inhibits the reaction [EGF protein results in increased phosphorylation of MAP2K2 protein] CTD PMID:21187475 sorafenib decreases phosphorylation EXP 6480464 sorafenib results in decreased phosphorylation of MAP2K2 protein CTD PMID:17341847 sorafenib decreases phosphorylation ISO RGD:1343460 6480464 sorafenib results in decreased phosphorylation of MAP2K2 protein CTD PMID:17341847 , PMID:18200035 tetrahydropalmatine decreases expression ISO RGD:1343460 6480464 tetrahydropalmatine results in decreased expression of MAP2K2 protein CTD PMID:20109541 thimerosal decreases expression ISO RGD:1343460 6480464 Thimerosal results in decreased expression of MAP2K2 mRNA CTD PMID:27188386 thioacetamide affects expression EXP 6480464 Thioacetamide affects the expression of MAP2K2 mRNA CTD PMID:19483382 titanium dioxide increases phosphorylation ISO RGD:62181 6480464 titanium dioxide analog results in increased phosphorylation of MAP2K2 protein CTD PMID:25111187 toluene affects expression EXP 6480464 Toluene affects the expression of MAP2K2 mRNA CTD PMID:21827849 trichloroethene increases expression ISO RGD:62181 6480464 Trichloroethylene results in increased expression of MAP2K2 mRNA CTD PMID:19448997 tyrphostin AG 1478 multiple interactions EXP 6480464 RTKI cpd inhibits the reaction [Oleylethanolamide results in increased phosphorylation of MAP2K2 protein] CTD PMID:16269455 urethane increases expression ISO RGD:1343460 6480464 Urethane results in increased expression of MAP2K2 mRNA CTD PMID:28818685 valdecoxib increases expression EXP 6480464 valdecoxib results in increased expression of MAP2K2 mRNA CTD PMID:24136188 valproic acid affects expression ISO RGD:62181 6480464 Valproic Acid affects the expression of MAP2K2 mRNA CTD PMID:17292431 vanadyl sulfate multiple interactions ISO RGD:1343460 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:10564177 , PMID:11943669 vanadyl sulfate increases phosphorylation ISO RGD:1343460 6480464 vanadyl sulfate results in increased phosphorylation of MAP2K2 protein CTD PMID:11943669 vanillin decreases expression ISO RGD:1343460 6480464 vanillin results in decreased expression of MAP2K2 mRNA CTD PMID:17178418 wogonin multiple interactions ISO RGD:62181 6480464 wogonin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased phosphorylation of MAP2K2 protein] CTD PMID:23362215 zinc sulfate multiple interactions ISO RGD:1343460 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:10564177 , PMID:11943669 zinc sulfate increases phosphorylation ISO RGD:1343460 6480464 Zinc Sulfate results in increased phosphorylation of MAP2K2 protein CTD PMID:11943669
Gene-Chemical Interaction Annotations
