Rab5b (RAB5B, member RAS oncogene family) - Rat Genome Database

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Gene: Rab5b (RAB5B, member RAS oncogene family) Rattus norvegicus
Analyze
Symbol: Rab5b
Name: RAB5B, member RAS oncogene family
RGD ID: 1306489
Description: Predicted to enable GDP binding activity; GTP-dependent protein binding activity; and GTPase activity. Predicted to be involved in several processes, including negative regulation of protein catabolic process; plasma membrane to endosome transport; and positive regulation of meiotic cell cycle process involved in oocyte maturation. Predicted to act upstream of or within endosome organization. Is anchored component of synaptic vesicle membrane. Orthologous to human RAB5B (RAB5B, member RAS oncogene family); PARTICIPATES IN endocytosis pathway; Entamoebiasis pathway; phagocytosis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC288779; ras-related protein Rab-5B
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.271,109,449 - 1,128,348 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl71,109,454 - 1,128,268 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx73,872,624 - 3,891,374 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.075,748,296 - 5,767,046 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.076,045,368 - 6,063,861 (-)NCBIRnor_WKY
Rnor_6.073,104,530 - 3,123,384 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl73,104,551 - 3,123,297 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.073,077,228 - 3,096,075 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,979,776 - 1,998,540 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.171,980,577 - 1,998,878 (-)NCBI
Celera7979,663 - 998,427 (-)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis. Pavlos NJ, etal., J Neurosci. 2010 Oct 6;30(40):13441-53. doi: 10.1523/JNEUROSCI.0907-10.2010.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7789520   PMID:10491193   PMID:11432782   PMID:12477932   PMID:15326289   PMID:17562788   PMID:18445495   PMID:18504258   PMID:19056867   PMID:19717423   PMID:20458337   PMID:20937701  
PMID:23533145   PMID:25002582  


Genomics

Comparative Map Data
Rab5b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.271,109,449 - 1,128,348 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl71,109,454 - 1,128,268 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx73,872,624 - 3,891,374 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.075,748,296 - 5,767,046 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.076,045,368 - 6,063,861 (-)NCBIRnor_WKY
Rnor_6.073,104,530 - 3,123,384 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl73,104,551 - 3,123,297 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.073,077,228 - 3,096,075 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,979,776 - 1,998,540 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.171,980,577 - 1,998,878 (-)NCBI
Celera7979,663 - 998,427 (-)NCBICelera
Cytogenetic Map7q11NCBI
RAB5B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381255,973,949 - 55,996,683 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1255,973,913 - 55,996,683 (+)EnsemblGRCh38hg38GRCh38
GRCh371256,367,733 - 56,390,467 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361254,654,129 - 54,674,757 (+)NCBINCBI36Build 36hg18NCBI36
Build 341254,654,128 - 54,674,753NCBI
Celera1256,020,546 - 56,041,174 (+)NCBICelera
Cytogenetic Map12q13.2NCBI
HuRef1253,406,584 - 53,429,353 (+)NCBIHuRef
CHM1_11256,334,808 - 56,357,578 (+)NCBICHM1_1
T2T-CHM13v2.01255,941,012 - 55,963,746 (+)NCBIT2T-CHM13v2.0
Rab5b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910128,511,980 - 128,532,160 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10128,513,044 - 128,532,133 (-)EnsemblGRCm39 Ensembl
GRCm3810128,677,170 - 128,696,284 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,677,175 - 128,696,264 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710128,114,235 - 128,133,324 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610128,080,826 - 128,099,213 (-)NCBIMGSCv36mm8
Celera10131,069,284 - 131,088,400 (-)NCBICelera
Cytogenetic Map10D3NCBI
Rab5b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554583,576,247 - 3,580,192 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554583,563,363 - 3,582,620 (+)NCBIChiLan1.0ChiLan1.0
RAB5B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11233,168,248 - 33,188,865 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1233,168,254 - 33,188,676 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01232,916,314 - 32,939,047 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
RAB5B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.110307,693 - 325,766 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl10320,366 - 323,844 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha10369,626 - 387,933 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.010314,513 - 332,609 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl10314,547 - 332,362 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.110292,317 - 310,622 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.010535,089 - 553,175 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.010659,367 - 677,675 (+)NCBIUU_Cfam_GSD_1.0
Rab5b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494558,461,972 - 58,483,266 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936646386,958 - 408,265 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB5B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl521,387,250 - 21,389,745 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1521,373,333 - 21,392,729 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RAB5B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11151,912,417 - 51,933,862 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1151,926,016 - 51,931,356 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037194,051,372 - 194,074,986 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rab5b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480212,059,503 - 12,066,296 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480212,058,916 - 12,065,177 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
RH129759  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.271,110,779 - 1,110,942 (+)MAPPERmRatBN7.2
Rnor_6.073,105,859 - 3,106,020NCBIRnor6.0
Rnor_5.073,078,559 - 3,078,720UniSTSRnor5.0
RGSC_v3.471,981,102 - 1,981,263UniSTSRGSC3.4
Celera7980,989 - 981,150UniSTS
Cytogenetic Map7q11UniSTS
RH132933  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.271,129,935 - 1,130,155 (+)MAPPERmRatBN7.2
Rnor_6.073,125,011 - 3,125,230NCBIRnor6.0
Rnor_5.073,097,711 - 3,097,930UniSTSRnor5.0
RGSC_v3.472,000,254 - 2,000,473UniSTSRGSC3.4
Celera71,000,141 - 1,000,360UniSTS
Cytogenetic Map7q11UniSTS
RH143244  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.271,127,589 - 1,127,699 (+)MAPPERmRatBN7.2
Rnor_6.073,122,665 - 3,122,774NCBIRnor6.0
Rnor_5.073,095,365 - 3,095,474UniSTSRnor5.0
RGSC_v3.471,997,908 - 1,998,017UniSTSRGSC3.4
Celera7997,795 - 997,904UniSTS
Cytogenetic Map7q11UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:355
Count of miRNA genes:201
Interacting mature miRNAs:256
Transcripts:ENSRNOT00000061878
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000061878   ⟹   ENSRNOP00000058595
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl71,109,454 - 1,128,268 (-)Ensembl
Rnor_6.0 Ensembl73,104,551 - 3,123,297 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000099796   ⟹   ENSRNOP00000079594
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl71,109,459 - 1,119,940 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000120020   ⟹   ENSRNOP00000092616
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl71,109,468 - 1,119,561 (-)Ensembl
RefSeq Acc Id: NM_001079936   ⟹   NP_001073405
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.271,109,454 - 1,128,222 (-)NCBI
Rnor_6.073,104,533 - 3,123,297 (-)NCBI
Rnor_5.073,077,228 - 3,096,075 (-)NCBI
RGSC_v3.471,979,776 - 1,998,540 (-)RGD
Celera7979,663 - 998,427 (-)RGD
Sequence:
RefSeq Acc Id: XM_006240750   ⟹   XP_006240812
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.271,109,449 - 1,128,348 (-)NCBI
Rnor_6.073,104,530 - 3,123,384 (-)NCBI
Rnor_5.073,077,228 - 3,096,075 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240751   ⟹   XP_006240813
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.271,109,449 - 1,128,325 (-)NCBI
Rnor_6.073,104,530 - 3,123,372 (-)NCBI
Rnor_5.073,077,228 - 3,096,075 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240752   ⟹   XP_006240814
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.271,109,449 - 1,128,295 (-)NCBI
Rnor_6.073,104,530 - 3,123,356 (-)NCBI
Rnor_5.073,077,228 - 3,096,075 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039078547   ⟹   XP_038934475
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.271,109,449 - 1,128,004 (-)NCBI
RefSeq Acc Id: XM_039078548   ⟹   XP_038934476
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.271,109,449 - 1,128,205 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001073405   ⟸   NM_001079936
- UniProtKB: A1L1J8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240812   ⟸   XM_006240750
- Peptide Label: isoform X1
- UniProtKB: A1L1J8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240813   ⟸   XM_006240751
- Peptide Label: isoform X1
- UniProtKB: A1L1J8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240814   ⟸   XM_006240752
- Peptide Label: isoform X1
- UniProtKB: A1L1J8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000058595   ⟸   ENSRNOT00000061878
RefSeq Acc Id: XP_038934476   ⟸   XM_039078548
- Peptide Label: isoform X1
- UniProtKB: A1L1J8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038934475   ⟸   XM_039078547
- Peptide Label: isoform X1
- UniProtKB: A1L1J8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000079594   ⟸   ENSRNOT00000099796
RefSeq Acc Id: ENSRNOP00000092616   ⟸   ENSRNOT00000120020

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A1L1J8-F1-model_v2 AlphaFold A1L1J8 1-215 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694947
Promoter ID:EPDNEW_R5472
Type:initiation region
Name:Rab5b_1
Description:RAB5B, member RAS oncogene family
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.073,123,352 - 3,123,412EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306489 AgrOrtholog
BioCyc Gene G2FUF-35340 BioCyc
Ensembl Genes ENSRNOG00000006130 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000058595 ENTREZGENE
  ENSRNOP00000058595.2 UniProtKB/TrEMBL
  ENSRNOP00000079594 ENTREZGENE
  ENSRNOP00000079594.1 UniProtKB/TrEMBL
  ENSRNOP00000092616 ENTREZGENE
  ENSRNOP00000092616.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000061878 ENTREZGENE
  ENSRNOT00000061878.5 UniProtKB/TrEMBL
  ENSRNOT00000099796 ENTREZGENE
  ENSRNOT00000099796.1 UniProtKB/TrEMBL
  ENSRNOT00000120020 ENTREZGENE
  ENSRNOT00000120020.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7098463 IMAGE-MGC_LOAD
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Ras_GTPase UniProtKB/TrEMBL
  Small_GTP-bd UniProtKB/TrEMBL
KEGG Report rno:288779 UniProtKB/TrEMBL
MGC_CLONE MGC:156695 IMAGE-MGC_LOAD
NCBI Gene 288779 ENTREZGENE
Pfam Ras UniProtKB/TrEMBL
PhenoGen Rab5b PhenoGen
PROSITE RAS UniProtKB/TrEMBL
SMART RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
TIGRFAMs small_GTP UniProtKB/TrEMBL
UniProt A0A8I5ZN01_RAT UniProtKB/TrEMBL
  A0A8I6AII6_RAT UniProtKB/TrEMBL
  A1L1J8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Rab5b  RAB5B, member RAS oncogene family   Rab5b_predicted  RAB5B, member RAS oncogene family (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Rab5b_predicted  RAB5B, member RAS oncogene family (predicted)      Symbol and Name status set to approved 70820 APPROVED