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Gene: Lrig3 (leucine-rich repeats and immunoglobulin-like domains 3) Rattus norvegicus

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Symbol:

Lrig3

Name:

leucine-rich repeats and immunoglobulin-like domains 3

RGD ID:

1561255

Description:

Predicted to act upstream of or within otolith morphogenesis. Predicted to be located in plasma membrane. Orthologous to human LRIG3 (leucine rich repeats and immunoglobulin like domains 3); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

leucine-rich repeats and immunoglobulin-like domains protein 3; LOC299830; MGC188535; RGD1561255; similar to Leucine-rich and immunoglobulin-like domains 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	63,701,724 - 63,751,898 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	63,701,778 - 63,752,261 (+)	Ensembl				GRCr8
mRatBN7.2	7	61,816,313 - 61,866,275 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	61,816,342 - 61,866,481 (+)	Ensembl				mRatBN7.2
Rnor_6.0	7	69,213,098 - 69,263,251 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	69,213,147 - 69,263,142 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	69,404,280 - 69,454,372 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	66,012,273 - 66,062,608 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	58,970,827 - 59,020,519 (+)	NCBI		Celera
Cytogenetic Map	7	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

basal cell carcinoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium dichloride (EXP,ISO)

calcitriol (ISO)

carbon nanotube (ISO)

chromium(6+) (ISO)

clofibrate (ISO)

cobalt dichloride (EXP,ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

decabromodiphenyl ether (EXP)

diethyl maleate (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

folic acid (ISO)

fonofos (ISO)

formaldehyde (ISO)

gentamycin (EXP)

lead(0) (ISO)

leflunomide (ISO)

lipopolysaccharide (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

melphalan (ISO)

methamphetamine (EXP)

nickel sulfate (ISO)

okadaic acid (ISO)

oxaliplatin (EXP)

paracetamol (EXP,ISO)

parathion (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

quercetin (ISO)

resorcinol (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

terbufos (ISO)

testosterone (ISO)

tetrachloromethane (EXP)

tetracycline (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

topotecan (EXP)

toxaphene (EXP)

trichloroethene (EXP)

trichostatin A (ISO)

trimellitic anhydride (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

otolith morphogenesis (IEA,ISO)

Cellular Component

membrane (IEA)

plasma membrane (IEA)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	GOA pipeline	RGD automated data pipeline
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:15632090	PMID:22664934	PMID:24086156	PMID:31119777

Genomics

Comparative Map Data

Lrig3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	63,701,724 - 63,751,898 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	63,701,778 - 63,752,261 (+)	Ensembl				GRCr8
mRatBN7.2	7	61,816,313 - 61,866,275 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	61,816,342 - 61,866,481 (+)	Ensembl				mRatBN7.2
Rnor_6.0	7	69,213,098 - 69,263,251 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	69,213,147 - 69,263,142 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	69,404,280 - 69,454,372 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	66,012,273 - 66,062,608 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	58,970,827 - 59,020,519 (+)	NCBI		Celera
Cytogenetic Map	7	q22	NCBI

LRIG3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	58,872,155 - 58,920,504 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	58,872,149 - 58,920,504 (-)	Ensembl			hg38	GRCh38
GRCh37	12	59,265,937 - 59,314,285 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	57,552,204 - 57,600,529 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	12	57,552,204 - 57,600,529	NCBI
Celera	12	58,927,578 - 58,975,904 (-)	NCBI		Celera
Cytogenetic Map	12	q14.1	NCBI
HuRef	12	56,314,531 - 56,362,936 (-)	NCBI		HuRef
CHM1_1	12	59,233,510 - 59,281,893 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	58,852,431 - 58,900,780 (-)	NCBI		T2T-CHM13v2.0

Lrig3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	125,802,088 - 125,851,228 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	125,802,037 - 125,851,228 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	10	125,966,219 - 126,015,359 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	125,966,168 - 126,015,359 (+)	Ensembl			mm10	GRCm38
MGSCv37	10	125,403,275 - 125,452,415 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	10	125,369,225 - 125,418,184 (+)	NCBI		MGSCv36	mm8
Celera	10	128,374,213 - 128,423,610 (+)	NCBI		Celera
Cytogenetic Map	10	D3	NCBI
cM Map	10	73.66	NCBI

Lrig3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955458	6,562,167 - 6,601,517 (-)	Ensembl
ChiLan1.0	NW_004955458	6,562,167 - 6,601,517 (-)	NCBI	ChiLan1.0	ChiLan1.0

LRIG3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	35,419,946 - 35,468,463 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	35,416,855 - 35,465,234 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	30,012,251 - 30,060,570 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	30,275,789 - 30,323,781 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	30,275,498 - 30,323,358 (+)	Ensembl			panPan2	panpan1.1

LRIG3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	2,723,836 - 2,772,630 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	2,724,951 - 2,772,636 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	2,789,369 - 2,838,992 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	2,737,466 - 2,787,369 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	2,739,331 - 2,787,479 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	2,714,388 - 2,764,026 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	2,956,608 - 3,006,074 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	3,082,721 - 3,131,801 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Lrig3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	55,940,378 - 55,981,106 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936646	2,886,069 - 2,929,552 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936646	2,889,331 - 2,929,836 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LRIG3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	24,066,623 - 24,117,970 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	5	24,066,611 - 24,117,971 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	25,903,031 - 25,952,707 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LRIG3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	54,806,138 - 54,853,811 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	54,806,579 - 54,853,645 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666037	191,070,125 - 191,117,716 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lrig3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624802	8,801,280 - 8,848,024 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624802	8,801,368 - 8,848,718 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Lrig3
322 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	324
Count of miRNA genes:	218
Interacting mature miRNAs:	258
Transcripts:	ENSRNOT00000032786
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
7411569	Bw137	Body weight QTL 137		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	7	21921195	66921195	Rat
1300179	Kidm5	Kidney mass QTL 5	3.51		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	43747012	135012528	Rat
2293667	Bss42	Bone structure and strength QTL 42	7.25	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra cross-sectional area (CMO:0001689)	7	47651439	92651439	Rat
10053722	Scort27	Serum corticosterone level QTL 27	2.41	0.0083	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	7	43228750	88228750	Rat
1641885	Alcrsp9	Alcohol response QTL 9			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	7	24099606	69099606	Rat
1549840	Bss5	Bone structure and strength QTL 5	9.8		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	7	24751841	69751841	Rat
2317035	Aia16	Adjuvant induced arthritis QTL 16	2.71		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	7	59238038	104238038	Rat
1300127	Srn1	Serum renin concentration QTL 1	3.87		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	7	29409683	84928080	Rat
10059605	Kidm47	Kidney mass QTL 47	2.91	0.05	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	7	47251783	65728867	Rat
2293678	Bss24	Bone structure and strength QTL 24	6.71	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	7	47651439	92651439	Rat
1358361	Sradr5	Stress Responsive Adrenal Weight QTL 5	5.55		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	7	43747012	108555253	Rat
631513	Scl7	Serum cholesterol level QTL 7	4.1		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	37960569	82960569	Rat
2293685	Bmd21	Bone mineral density QTL 21	4.2	0.0003	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	7	47651439	92651439	Rat
10755453	Coatc12	Coat color QTL 12		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	31112832	76112832	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	44421311	118198041	Rat
10755451	Coatc11	Coat color QTL 11		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	17944357	62944357	Rat
634326	Hc3	Hypercalciuria QTL 3	2.1		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	7	42787314	87787314	Rat
2317059	Aia15	Adjuvant induced arthritis QTL 15	2.46		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	7	17004598	62004598	Rat
2293696	Bmd32	Bone mineral density QTL 32	5.1	0.0001	femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	7	47651439	92651439	Rat
7411605	Foco14	Food consumption QTL 14	24.1	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	34293282	79293282	Rat
1300151	Bp181	Blood pressure QTL 181	3.36		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	7	53612714	103945643	Rat
1643004	Pain2	Pain QTL 2	1		mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	7	9462246	98011544	Rat
738030	Anxrr8	Anxiety related response QTL 8	4.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	46590070	91590070	Rat
1300149	Cm6	Cardiac mass QTL 6	4.09		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	7	43747099	102228765	Rat
631534	Lnnr1	Liver neoplastic nodule remodeling QTL 1	3.85	0.001	liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)	7	34293282	79293282	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	924703	115097879	Rat
2293707	Bss32	Bone structure and strength QTL 32	7.64	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	7	47651439	92651439	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	41333674	119109060	Rat
2293644	Bmd29	Bone mineral density QTL 29	5.4	0.0001	femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	7	47651439	92651439	Rat
70190	Mcs6	Mammary carcinoma susceptibility QTL 6	2.29		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	7	26737401	63902784	Rat
2300178	Bmd54	Bone mineral density QTL 54	5.3	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	7	47651439	92651439	Rat
1298528	Bp169	Blood pressure QTL 169		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	61074194	106074194	Rat
61428	Scl3	Serum cholesterol level QTL 3	3.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	44867533	89867533	Rat
1300132	Bp182	Blood pressure QTL 182	3.49		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	19654317	84928080	Rat
10402855	Bp379	Blood pressure QTL 379		0.21	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	29409683	74409683	Rat
61435	Cia4	Collagen induced arthritis QTL 4	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	7	58113224	62004598	Rat

Markers in Region

BE116579

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	61,841,729 - 61,841,896 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	69,238,514 - 69,238,680	NCBI	Rnor6.0
Rnor_5.0	7	69,429,674 - 69,429,840	UniSTS	Rnor5.0
RGSC_v3.4	7	66,037,396 - 66,037,562	UniSTS	RGSC3.4
Celera	7	58,995,876 - 58,996,042	UniSTS
Cytogenetic Map	7	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	161	91	90	59	75	59	6	338	175	11	140	80	92	31	15	15

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001432458	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001055013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_216905	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC100645	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC168689	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000032786 ⟹ ENSRNOP00000030604

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	63,701,778 - 63,751,899 (+)	Ensembl
mRatBN7.2 Ensembl	7	61,816,342 - 61,866,481 (+)	Ensembl
Rnor_6.0 Ensembl	7	69,213,147 - 69,263,142 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000145354 ⟹ ENSRNOP00000108414

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	63,701,823 - 63,752,261 (+)	Ensembl

RefSeq Acc Id:

XM_216905 ⟹ XP_216905

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	63,701,724 - 63,751,898 (+)	NCBI
mRatBN7.2	7	61,816,313 - 61,866,275 (+)	NCBI
Rnor_6.0	7	69,213,098 - 69,263,251 (+)	NCBI
Rnor_5.0	7	69,404,280 - 69,454,372 (+)	NCBI
RGSC_v3.4	7	66,012,273 - 66,062,608 (+)	RGD

Sequence:

show sequence

GTTCCGCCGTGCGGGGACCTCGCGCCCGGCCGCCGCCGCAGGCGGAAAAGTTTCTCAGCGTGCG
ATCGCGCTTTCGGACGCCGCTCGGGCTGCCTTCTCACCGTGGCTGCCGATCCTCCGCTGCTAGC
TCTTCCGCTGTGCACAGGCATGAGAGGCCTTCCGTGCCGGGTCTGAGCGGCCAGGAACACGAGG
CGGTGATCGGCGTGTCCAGCCCGGTCTGTGAGTCGGTGCTTTTGGAGGTGCTCGAGGCTGCAGA
GCTCCCGGCCGAACCGGAGGCGGCGGGGCGCGCGGCGATGGGTGCTCCCGGGCTCCGAGCTGCA
GCTGCGGCGCTGGGACTGCTGCTCTGCGCGGGGCTGGGGCGCGCGGGCCCGGCAGGGAGCGGAG
GCCACGGGGCGCCCGGGCAGCTCTCGGACGAAGCTACGCGGCGCCCGTGCCCAGCCGCCTGCCA
CTGCCTCGGGGATCTGCTGGACTGCAGCCGCCGGCGGCTGATTCGCCTTCCCGATCCTCTCCCG
GCCTGGGTCACTCGGCTGGACCTGAGTCACAACAGATTATCATTTATCCAAGCGAGTTCCCTGA
GCCACCTTCAAAGCCTTCAAGAAGTGAAGCTGAACAACAATGAATTAGAGACCATCCCAAACCT
GGGACCAGTTTCTGCGAACATTAGACAGCTGTCCTTGGCAGGGAACGCCATCGACAAAATCCTC
CCTGAGCAGCTGGAAGCATTTCAGTCCCTGGAGACTTTGGACCTGAGCAACAACAACATTTCAG
AACTCAGAACAGCATTTCCACCCTTACAACTCAAGTATCTGTATATCAATAGCAACCGAGTTAC
GTCCATGGAACCGGGGTATTTTGACAATTTGGGGAGCACTCTCCTGGTGCTGAAGCTGAACAGG
AACCGCATCTCAGCCATCCCCCCCAAAATGTTTAAATTGCCTCAGCTGCAGCACCTTGAACTGA
ACAGAAACAAGATTAAGAACGTGGATGGACTCACATTCCAGGGGCTTGGCGCATTGAAGTCCCT
GAAAATGCAAAGAAATGGAGTGACTAAGCTCATGGATGGAGCTTTTTGGGGGCTGAGCAACATG
GAAATCCTGCAGCTGGACCATAACAACCTAACCGAGATTACCAAAGGCTGGCTCTATGGCTTGT
TGATGCTACGGGAGCTTCATCTGAGCCAGAATGCCATCAACAGGATCAGCCCGGACGCCTGGGA
GTTCTGCCAGAAACTCAGTGAGCTAGACCTGACTTTCAACCACTTATCCAGGCTAGACGATTCC
AGCTTCCTTGGCCTAAGCCTACTAAATGCCCTCCACGTTGGGAATAACAAAGTCAGCTACATTG
CTGATTGTGCCTTCCGGGGGCTTTCCAGTTTAAAGACTTTGGATCTGAGGAACAATGAAATTTC
ATGGACCATCGAAGACATGAATGGAGCATTCTCTGGGCTGGACAAATTGAGGCAACTAATTCTC
CAGGGAAACCGGATTCGATCTATTACCAAAAAGGCCTTCGCTGGTTTGGACACATTGGAACACC
TTGACCTCAGTGGCAATGCCATCATGTCTCTGCAAAACAATGCATTTTCCCAAATGAAGAAACT
TCAGCAACTGCATCTAAATACATCAAGCCTTTTGTGTGATTGCCAGCTAAAATGGCTTCCACAG
TGGGTGGCAGAGAACAACTTTCAGAGCTTCGTGAATGCCAGTTGCGCCCACCCTCAGCCGCTGA
AAGGGAGAAGTATTTTTACTGTCAGCCCAGATGGCTTTGTGTGTGATGACTTTCCCAAACCCCA
GATCACGGTCCAGCCGGAAACACAGTCAGCCATAAAGGGCTCCGACGTGAGTTTTACCTGCTCG
GCCGCTAGCAGCAGCGACTCCCCTATGACGTTCGCTTGGAAGAAAGACAACGAAGCGCTTCAGG
ACGCTGAAATGGAGAACTATGCGCACCTCCGGGCCCAGGGAGGCGAGCTGATGGAGTACACCAC
CATCCTGAGGCTCCGCAACGTGGAATTTGCCAGCGAAGGGAGGTACCAGTGCGTCATCTCCAAC
CACTTCGGTTCATCGTACTCCGTCAAAGCCAGGCTCACCATCAACATGTTGCCTTCCTTTACCA
AGACCCCCATGGACCTCACCATCCGTGCTGGGGCCATGGCCCGCCTGGAGTGTGCTGCTGTGGG
ACACCCAGCCCCGCAGATAGCCTGGCAGAAGGATGGAGGTATAGACTTCCCAGCTGCCCGGGAG
AGACGCATGCACGTGATGCCTGAGGATGACGTGTTCTTCATCGTGGACGTGAAGATTGAGGACA
TCGGGGTATACAGCTGCACGGCTCAAAACAGTGCGGGGAGCGTCTCTGCAAACGCAACCCTGAC
CGTGCTAGAGACACCGTCGTTTTTGCGGCCCTTGTTAGACAGAACTGTCACCAAGGGAGAAACA
GCAGTCCTGCAGTGCATTGCTGGAGGGAGCCCGCCCCCTCGGCTGAACTGGACAAAAGATGACA
GCCCTTTGGTGGTGACCGAGAGGCACTTTTTCGCAGCAGGCAATCAGCTGCTGATCATTGTGGA
CTCGGACGTCAGTGACGCGGGGAAATACACGTGCGAGATGTCCAATACCCTTGGTACTGAGAGA
GGCAATGTTCGCCTCAGTGTGATCCCTACTCCAACCTGCGACTCCCCTCACATGACTGCCCCGT
CGCTGGACGGTGACGGGTGGGCCACTGTGGGCGTGGTCATCATAGCCGTGGTTTGCTGTGTGGT
GGGCACGTCCCTCGTATGGGTGGTCATTATATACCACACAAGGCGGAGGAACGAGGACTGCAGC
ATTACCAACACAGATGAGACCAACTTGCCCGCCGATATCCCTAGTTATTTATCATCTCAGGGGA
CATTAGCTGACAGGCAGGATGGGTACATCTCCTCAGAGAACGGAAGCCACCACCAGTTCGTCAC
TTCTTCGGGAGGTGGATTTTTCTTGCCACAACATGACAGTGCTGGGACCTGCCATTTTGACGAC
AGCAGTGAAGCGGATGTGGAAGCGGCCCCTGATCCATTTCTCTGCCCATTCGTGAGCTCCTCGG
GCCCTGTGTATCTGAAGGGGAATCTGTACGGCCCAGATCCATTTGAAGTGTATCTTCCAGGTTG
CAGTTCTGACCCGAGGATCGCTTTAATGGACCACTGTGAGTCGAGCTACACAAAGAAGGACTGC
TTCTCATGCGCTCATCCCTCAGAGGAACCCTGTGAACGGAGCCTCAAGAGCATCCCGTGGCCAC
ATTCTAGAAAGCTCATGAACTCCGCGTTCTCTCAGAACGAGGGACCTGCGGTTCAGACTCTGCG
TCTAAACAAGTCCGTGGATTTTAGTACAAGTCCAGAACCAGGATCGGCTACTTCAAGTAACTCT
TTCATGGGAACCTTCGGAAAACCTCTGAGGAGACCGCAACTGGATGCCTTGTCGAGCTTCGCAC
AACCACCAGACTGTCAGCCAAGGCCCTGTCACGGGAAATCACTTTCCCCACCAGAGCTGGACTC
TGAGTCAGAAGAAGATGAAAAAGAAAGGACAGATTTTCGGGAAGAAAATCACAGGTGTACTTAT
CAACAGATATTGCACAGTTACAGGACTCCAGACCGACAGCCTTGTGATTCAGACACATAGACTG
GAGGGGACCAAGGAAAAGTTTCCGCATACTACCTCAGCTGGGCTTCTATTTAAAAGACACAGAA
TCCTATGTTTTTAAACAGACTTACAAAGTTTAAAAAGAAGAAAAAAAGATGCTTTATTTATATA
GATGAACCAAAATTACAAAAACATTATAAAAATTTTATACCGGGAATAACTTTCATATAAAAAA
ATGCATCCTTAAAAGTATTTTATAACTTTGTTTTATATGAAAATATCTTATGTAAATTAATGGT
ATGAATCCATGACTATTTTATGTATTTTTATAAAGCCAGATTCCTTTTATTGAG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001419387	(Get FASTA)	NCBI Sequence Viewer
	XP_216905	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI68689	(Get FASTA)	NCBI Sequence Viewer
	EDM16521	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000030604
	ENSRNOP00000030604.5

RefSeq Acc Id:

XP_216905 ⟸ XM_216905

- Sequence:

show sequence

MGAPGLRAAAAALGLLLCAGLGRAGPAGSGGHGAPGQLSDEATRRPCPAACHCLGDLLDCSRRR
LIRLPDPLPAWVTRLDLSHNRLSFIQASSLSHLQSLQEVKLNNNELETIPNLGPVSANIRQLSL
AGNAIDKILPEQLEAFQSLETLDLSNNNISELRTAFPPLQLKYLYINSNRVTSMEPGYFDNLGS
TLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMD
GAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLRELHLSQNAINRISPDAWEFCQKLSELDLTF
NHLSRLDDSSFLGLSLLNALHVGNNKVSYIADCAFRGLSSLKTLDLRNNEISWTIEDMNGAFSG
LDKLRQLILQGNRIRSITKKAFAGLDTLEHLDLSGNAIMSLQNNAFSQMKKLQQLHLNTSSLLC
DCQLKWLPQWVAENNFQSFVNASCAHPQPLKGRSIFTVSPDGFVCDDFPKPQITVQPETQSAIK
GSDVSFTCSAASSSDSPMTFAWKKDNEALQDAEMENYAHLRAQGGELMEYTTILRLRNVEFASE
GRYQCVISNHFGSSYSVKARLTINMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDG
GIDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSVSANATLTVLETPSFLRPLL
DRTVTKGETAVLQCIAGGSPPPRLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCE
MSNTLGTERGNVRLSVIPTPTCDSPHMTAPSLDGDGWATVGVVIIAVVCCVVGTSLVWVVIIYH
TRRRNEDCSITNTDETNLPADIPSYLSSQGTLADRQDGYISSENGSHHQFVTSSGGGFFLPQHD
SAGTCHFDDSSEADVEAAPDPFLCPFVSSSGPVYLKGNLYGPDPFEVYLPGCSSDPRIALMDHC
ESSYTKKDCFSCAHPSEEPCERSLKSIPWPHSRKLMNSAFSQNEGPAVQTLRLNKSVDFSTSPE
PGSATSSNSFMGTFGKPLRRPQLDALSSFAQPPDCQPRPCHGKSLSPPELDSESEEDEKERTDF
REENHRCTYQQILHSYRTPDRQPCDSDT

hide sequence

Ensembl Acc Id:

ENSRNOP00000030604 ⟸ ENSRNOT00000032786

Ensembl Acc Id:

ENSRNOP00000108414 ⟸ ENSRNOT00000145354

Protein Domains

Ig-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-G3V8Y2-F1-model_v2	AlphaFold	G3V8Y2	1-1116	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695246

Promoter ID:

EPDNEW_R5766

Type:

initiation region

Name:

Lrig3_1

Description:

leucine-rich repeats and immunoglobulin-like domains 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	69,213,143 - 69,213,203	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1561255	AgrOrtholog
BioCyc Gene	G2FUF-33812	BioCyc
Ensembl Genes	ENSRNOG00000007654	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000032786	ENTREZGENE
	ENSRNOT00000032786.6	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
	3.80.10.10	UniProtKB/TrEMBL
InterPro	Cys-rich_flank_reg_C	UniProtKB/TrEMBL
	Dev_Immune_Receptor	UniProtKB/TrEMBL
	Ig-like_dom	UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	Ig_I-set	UniProtKB/TrEMBL
	Ig_sub	UniProtKB/TrEMBL
	Ig_sub2	UniProtKB/TrEMBL
	L_dom-like	UniProtKB/TrEMBL
	Leu-rich_rpt	UniProtKB/TrEMBL
	Leu-rich_rpt_typical-subtyp	UniProtKB/TrEMBL
	LRFN	UniProtKB/TrEMBL
KEGG Report	rno:299830	UniProtKB/TrEMBL
NCBI Gene	299830	ENTREZGENE
PANTHER	KEKKON 5, ISOFORM A	UniProtKB/TrEMBL
	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 6	UniProtKB/TrEMBL
	SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN	UniProtKB/TrEMBL
	SYNAPTIC ADHESION-LIKE MOLECULE SALM	UniProtKB/TrEMBL
Pfam	I-set	UniProtKB/TrEMBL
	Ig_3	UniProtKB/TrEMBL
	LRR_1	UniProtKB/TrEMBL
	LRR_8	UniProtKB/TrEMBL
PhenoGen	Lrig3	PhenoGen
PRINTS	LEURICHRPT	UniProtKB/TrEMBL
PROSITE	IG_LIKE	UniProtKB/TrEMBL
	LRR	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000007654	RatGTEx
SMART	IGc2	UniProtKB/TrEMBL
	LRR_SD22	UniProtKB/TrEMBL
	LRR_TYP	UniProtKB/TrEMBL
	LRRCT	UniProtKB/TrEMBL
	SM00409	UniProtKB/TrEMBL
Superfamily-SCOP	L domain-like	UniProtKB/TrEMBL
	SSF48726	UniProtKB/TrEMBL
UniProt	A0A0G2QC29_RAT	UniProtKB/TrEMBL
	A6HQQ1	ENTREZGENE, UniProtKB/TrEMBL
	B5DEJ0	ENTREZGENE
	G3V8Y2	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	B5DEJ0	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-02-29	Lrig3	leucine-rich repeats and immunoglobulin-like domains 3	RGD1561255_predicted	similar to Leucine-rich and immunoglobulin-like domains 3 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1561255_predicted	similar to Leucine-rich and immunoglobulin-like domains 3 (predicted)	LOC299830	similar to Leucine-rich and immunoglobulin-like domains 3	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC299830	similar to Leucine-rich and immunoglobulin-like domains 3			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD