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Gene: Ndufa12 (NADH:ubiquinone oxidoreductase subunit A12) Rattus norvegicus
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Symbol: Ndufa12
Name: NADH:ubiquinone oxidoreductase subunit A12
Description: Predicted to have NADH dehydrogenase (ubiquinone) activity and electron transfer activity. Predicted to be involved in mitochondrial ATP synthesis coupled electron transport and response to oxidative stress. Predicted to localize to the cytosol and mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in mitochondrial complex I deficiency. Orthologous to human NDUFA12 (NADH:ubiquinone oxidoreductase subunit A12); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; INTERACTS WITH bisphenol A; Brodifacoum; dibutyl phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC299739; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; RGD1311462; similar to RIKEN cDNA 2410011G03
Orthologs:
Homo sapiens (human) : NDUFA12 (NADH:ubiquinone oxidoreductase subunit A12)  HGNC  Alliance
Mus musculus (house mouse) : Ndufa12 (NADH:ubiquinone oxidoreductase subunit A12)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ndufa12 (NADH:ubiquinone oxidoreductase subunit A12)
Pan paniscus (bonobo/pygmy chimpanzee) : NDUFA12 (NADH:ubiquinone oxidoreductase subunit A12)
Canis lupus familiaris (dog) : NDUFA12 (NADH:ubiquinone oxidoreductase subunit A12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ndufa12 (NADH:ubiquinone oxidoreductase subunit A12)
Sus scrofa (pig) : NDUFA12 (NADH:ubiquinone oxidoreductase subunit A12)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0735,125,516 - 35,163,182 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0735,193,809 - 35,229,887 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4731,349,357 - 31,376,151 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1731,366,696 - 31,396,332 (+)NCBI
Celera725,862,251 - 25,888,618 (+)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ndufa12
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311462
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.