Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and microtubule binding activity. Involved in liver regeneration and prostate gland development. Predicted to be located in axoneme; cytosol; and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Biomarker of ocular hypertension. Orthologous to human GLI1 (GLI family zinc finger 1); PARTICIPATES IN altered Hedgehog signaling pathway; Hedgehog signaling pathway; pancreatic cancer pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one.
epigallocatechin gallate inhibits the reaction [Diethylnitrosamine results in increased expression of GLI1 mRNA], epigallocatechin gallate inhibits the reaction [Diethylnitrosamine results in increased expression of GLI1 protein]
[Estradiol co-treated with TGFB1 protein] results in increased expression of GLI1 mRNA, Estradiol inhibits the reaction [SHH protein results in increased expression of GLI1 mRNA]
[Estradiol co-treated with Progesterone] results in increased expression of GLI1 mRNA, Estradiol inhibits the reaction [SHH protein results in increased expression of GLI1 mRNA]
[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of GLI1 mRNA
[goralatide co-treated with Captopril] inhibits the reaction [Silicon Dioxide results in increased expression of GLI1 protein], goralatide inhibits the reaction [Silicon Dioxide results in increased expression of GLI1 protein]
[goralatide co-treated with Captopril] inhibits the reaction [AGT protein results in increased expression of GLI1 protein], goralatide inhibits the reaction [AGT protein results in increased expression of GLI1 protein]
Chlorodiphenyl (54% Chlorine) results in decreased expression of GLI1 mRNA, Chlorodiphenyl (54% Chlorine) results in decreased expression of GLI1 protein
[Arsenic Trioxide co-treated with Curcumin] inhibits the reaction [Cisplatin results in increased expression of GLI1 protein], Arsenic Trioxide inhibits the reaction [Cisplatin results in increased expression of GLI1 protein]
[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of GLI1 mRNA
[goralatide co-treated with Captopril] inhibits the reaction [Silicon Dioxide results in increased expression of GLI1 protein], Captopril inhibits the reaction [Silicon Dioxide results in increased expression of GLI1 protein]
[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of GLI1 mRNA, SHH protein affects the reaction [[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of GLI1 mRNA]
[Arsenic Trioxide co-treated with Curcumin] inhibits the reaction [Cisplatin results in increased expression of GLI1 protein], Curcumin inhibits the reaction [Cisplatin results in increased expression of GLI1 protein]
GLI1 affects the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of CCND1 protein], GLI1 affects the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of MYC protein]
[Arsenic Trioxide co-treated with Curcumin] inhibits the reaction [Cisplatin results in increased expression of GLI1 protein], Arsenic Trioxide inhibits the reaction [Cisplatin results in increased expression of GLI1 protein]
[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of GLI1 mRNA
hyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of GLI1 mRNA], hyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of GLI1 protein]
[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of GLI1 mRNA
[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of GLI1 mRNA
cyclopamine inhibits the reaction [SHH protein inhibits the reaction [Lipopolysaccharides results in decreased expression of and results in decreased localization of GLI1 protein]] more ...
tetramethylpyrazine inhibits the reaction [Paraquat results in increased expression of GLI1 mRNA], tetramethylpyrazine inhibits the reaction [Paraquat results in increased expression of GLI1 protein]
[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of GLI1 mRNA, SHH protein affects the reaction [[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of GLI1 mRNA]
hyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of GLI1 mRNA], hyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of GLI1 protein]
cyclopamine inhibits the reaction [resveratrol results in increased expression of GLI1 protein], resveratrol results in increased expression of and affects the localization of GLI1 protein
[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of GLI1 mRNA
cyclopamine inhibits the reaction [Sodium Fluoride results in increased expression of GLI1 mRNA], cyclopamine inhibits the reaction [Sodium Fluoride results in increased expression of GLI1 protein]
GANT 61 inhibits the reaction [Carbon Tetrachloride results in increased expression of GLI1 mRNA], GANT 61 inhibits the reaction [Carbon Tetrachloride results in increased expression of GLI1 protein]
tetramethylpyrazine inhibits the reaction [Paraquat results in increased expression of GLI1 mRNA], tetramethylpyrazine inhibits the reaction [Paraquat results in increased expression of GLI1 protein]
theaflavin inhibits the reaction [Diethylnitrosamine results in increased expression of GLI1 mRNA], theaflavin inhibits the reaction [Diethylnitrosamine results in increased expression of GLI1 protein]
cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GLI1 mRNA]] more ...
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
