Gadd45b (growth arrest and DNA-damage-inducible, beta) - Rat Genome Database

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Gene: Gadd45b (growth arrest and DNA-damage-inducible, beta) Rattus norvegicus
Analyze
Symbol: Gadd45b
Name: growth arrest and DNA-damage-inducible, beta
RGD ID: 1309080
Description: Predicted to be involved in positive regulation of MAPK cascade; positive regulation of apoptotic process; and regulation of cell cycle. Predicted to act upstream of or within negative regulation of protein kinase activity and positive regulation of MAPK cascade. Predicted to be active in cytoplasm and nucleus. Orthologous to human GADD45B (growth arrest and DNA damage inducible beta); PARTICIPATES IN interleukin-12 signaling pathway; p38 MAPK signaling pathway; cell cycle pathway, mitotic; INTERACTS WITH (S)-colchicine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: growth arrest and DNA damage-inducible protein GADD45 beta; growth arrest and DNA-damage-inducible 45 beta; LOC299626; MGC105966
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr879,428,689 - 9,430,991 (-)NCBIGRCr8
mRatBN7.278,778,004 - 8,780,306 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl78,778,007 - 8,780,046 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx711,662,083 - 11,664,112 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0713,537,577 - 13,539,606 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0711,404,118 - 11,406,147 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0711,646,283 - 11,648,338 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl711,646,269 - 11,648,322 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0711,813,536 - 11,815,569 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4710,289,073 - 10,291,102 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1710,289,072 - 10,291,102 (-)NCBI
Celera76,964,215 - 6,966,244 (-)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gadd45bRatCOVID-19  ISOGADD45B (Homo sapiens)9068941mRNA:increased expression:bronchoalveolar lavage (human)RGDPMID:32407669 and REF_RGD_ID:30296672
Gadd45bRatCOVID-19  ISOGADD45B (Homo sapiens)9068941mRNA:increased expression:CD14++ monocytes (human)RGDPMID:32377375 and REF_RGD_ID:32716422
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gadd45bRatNeurodevelopmental Disorders  ISOGADD45B (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
Gadd45bRatprogressive myoclonus epilepsy 9  ISOGADD45B (Homo sapiens)8554872ClinVar Annotator: match by term: Progressive myoclonic epilepsy type 9ClinVarPMID:28492532
Gadd45bRatRASopathy  ISOGADD45B (Homo sapiens)8554872ClinVar Annotator: match by term: RASopathyClinVarPMID:23379592 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gadd45bRatArsenic Poisoning  ISOGADD45B (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16835338
Gadd45bRatskin disease  ISOGADD45B (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16835338

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gadd45bRat(-)-citrinin increases expressionISOGADD45B (Homo sapiens)6480464Citrinin results in increased expression of GADD45B mRNACTDPMID:19361540
Gadd45bRat(-)-citrinin multiple interactionsISOGADD45B (Homo sapiens)6480464U 0126 inhibits the reaction [Citrinin results in increased expression of GADD45B mRNA]CTDPMID:19361540
Gadd45bRat(1->4)-beta-D-glucan multiple interactionsISOGadd45b (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of GADD45B mRNACTDPMID:36331819
Gadd45bRat(E)-thiamethoxam decreases expressionISOGadd45b (Mus musculus)6480464Thiamethoxam results in decreased expression of GADD45B mRNACTDPMID:33533595
Gadd45bRat(S)-colchicine increases expressionEXP 6480464Colchicine results in increased expression of GADD45B mRNACTDPMID:20624997
Gadd45bRat1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expressionISOGadd45b (Mus musculus)6480464o and p'-DDT affects the expression of GADD45B mRNACTDPMID:18925944
Gadd45bRat17alpha-ethynylestradiol affects expressionISOGadd45b (Mus musculus)6480464Ethinyl Estradiol affects the expression of GADD45B mRNACTDPMID:17555576
Gadd45bRat17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of GADD45B mRNACTDPMID:29097150
Gadd45bRat17alpha-ethynylestradiol increases expressionISOGadd45b (Mus musculus)6480464Ethinyl Estradiol results in increased expression of GADD45B mRNACTDPMID:17942748
Gadd45bRat17alpha-ethynylestradiol multiple interactionsISOGadd45b (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GADD45B mRNA and Ethinyl Estradiol inhibits the reaction [IL1B protein results in increased expression of GADD45B mRNA]CTDPMID:12072388 and PMID:17942748
Gadd45bRat17beta-estradiol decreases expressionISOGADD45B (Homo sapiens)6480464Estradiol results in decreased expression of GADD45B mRNACTDPMID:19167446
Gadd45bRat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of GADD45B mRNACTDPMID:32145629
Gadd45bRat17beta-estradiol multiple interactionsISOGADD45B (Homo sapiens)6480464[Estradiol co-treated with TGFB1 protein] results in increased expression of GADD45B mRNACTDPMID:30165855
Gadd45bRat17beta-estradiol increases expressionISOGadd45b (Mus musculus)6480464Estradiol results in increased expression of GADD45B mRNA and Estradiol results in increased expression of GADD45B proteinCTDPMID:23684557 and PMID:39298647
Gadd45bRat17beta-estradiol multiple interactionsISOGadd45b (Mus musculus)6480464Estradiol promotes the reaction [GADD45B protein binds to CYP2B10 promoter]CTDPMID:23684557
Gadd45bRat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISOGadd45b (Mus musculus)64804642 more ...CTDPMID:21851831
Gadd45bRat2,2',4,4',5,5'-hexachlorobiphenyl increases expressionISOGadd45b (Mus musculus)64804642 more ...CTDPMID:20005886 and PMID:21851831
Gadd45bRat2,2',4,4'-Tetrabromodiphenyl ether increases expressionEXP 64804642 more ...CTDPMID:31826744
Gadd45bRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOGadd45b (Mus musculus)64804642 more ...CTDPMID:17942748 more ...
Gadd45bRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of GADD45B mRNACTDPMID:33387578

1 to 20 of 334 rows

Biological Process
1 to 13 of 13 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gadd45bRatnegative regulation of protein kinase activity acts_upstream_of_or_withinISOGadd45b (Mus musculus)1624291 PMID:12124778RGDPMID:12124778
Gadd45bRatpositive regulation of apoptotic process involved_inISOGADD45B (Homo sapiens)1624291 PMID:9827804RGDPMID:9827804
Gadd45bRatpositive regulation of apoptotic process involved_inIEAUniProtKB:O75293 and ensembl:ENSP000002156311600115GO_REF:0000107EnsemblGO_REF:0000107
Gadd45bRatpositive regulation of JNK cascade involved_inISOGADD45B (Homo sapiens)1624291 PMID:9827804RGDPMID:9827804
Gadd45bRatpositive regulation of JNK cascade involved_inIEAUniProtKB:O75293 and ensembl:ENSP000002156311600115GO_REF:0000107EnsemblGO_REF:0000107
Gadd45bRatpositive regulation of MAPK cascade acts_upstream_of_or_withinIEAUniProtKB:P22339 and ensembl:ENSMUSP000000154561600115GO_REF:0000107EnsemblGO_REF:0000107
Gadd45bRatpositive regulation of MAPK cascade acts_upstream_of_or_withinISOGadd45b (Mus musculus)1624291 PMID:12213961RGDPMID:12213961
Gadd45bRatpositive regulation of p38MAPK cascade involved_inISOGADD45B (Homo sapiens)1624291 PMID:9827804RGDPMID:9827804
Gadd45bRatpositive regulation of p38MAPK cascade involved_inIEAUniProtKB:O75293 and ensembl:ENSP000002156311600115GO_REF:0000107EnsemblGO_REF:0000107
Gadd45bRatregulation of cell cycle involved_inIBAMGI:107776 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Gadd45bRatregulation of cell cycle involved_inIEAInterPro:IPR0248241600115GO_REF:0000002InterProGO_REF:0000002
Gadd45bRatregulation of cell cycle acts_upstream_of_or_withinIEAUniProtKB:P22339 and ensembl:ENSMUSP000000154561600115GO_REF:0000107EnsemblGO_REF:0000107
Gadd45bRatregulation of cell cycle acts_upstream_of_or_withinISOGadd45b (Mus musculus)1624291 PMID:12124778RGDPMID:12124778
1 to 13 of 13 rows

Cellular Component

  
Object Symbol
Species
Term
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Evidence
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Reference
Notes
Source
Original Reference(s)
Gadd45bRatcytoplasm located_inISOGADD45B (Homo sapiens)1624291 PMID:9827804RGDPMID:9827804
Gadd45bRatcytoplasm is_active_inIBAPANTHER:PTN000823659 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Gadd45bRatcytoplasm located_inIEAUniProtKB:O75293 and ensembl:ENSP000002156311600115GO_REF:0000107EnsemblGO_REF:0000107
Gadd45bRatnucleus located_inIEAUniProtKB:O75293 and ensembl:ENSP000002156311600115GO_REF:0000107EnsemblGO_REF:0000107
Gadd45bRatnucleus located_inIEAInterPro:IPR0248241600115GO_REF:0000002InterProGO_REF:0000002
Gadd45bRatnucleus is_active_inIBAFB:FBgn0033153 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Gadd45bRatnucleus located_inISOGADD45B (Homo sapiens)1624291 PMID:9827804RGDPMID:9827804

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gadd45bRatprotein binding enablesISOGADD45B (Homo sapiens)1624291UniProtKB:O14733 more ...RGDPMID:12052864 more ...
Gadd45bRatprotein binding enablesISOGadd45b (Mus musculus)1624291PR:P24860 more ...RGDPMID:12124778 and PMID:12716909

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gadd45bRatcell cycle pathway, mitotic  IEA 6907045 KEGGrno:04110
Gadd45bRatmitogen activated protein kinase signaling pathway   IEA 6907045 KEGGrno:04010
Gadd45bRatp53 signaling pathway   IEA 6907045 KEGGrno:04115

Imported Annotations - PID (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gadd45bRatinterleukin-12 signaling pathway  ISOGADD45B (Homo sapiens)6484113 PIDPID:200045
Gadd45bRatp38 MAPK signaling pathway   ISOGADD45B (Homo sapiens)6484113 PIDPID:200018

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:9827804   PMID:12124778   PMID:12213961   PMID:12477932   PMID:16528573   PMID:18977442   PMID:20154065   PMID:23948959   PMID:25324012   PMID:25678854   PMID:25728234   PMID:26676568  
PMID:26698301   PMID:26882903   PMID:27086974   PMID:27590577   PMID:31043581   PMID:33421485   PMID:33784505   PMID:37988908  



Gadd45b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr879,428,689 - 9,430,991 (-)NCBIGRCr8
mRatBN7.278,778,004 - 8,780,306 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl78,778,007 - 8,780,046 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx711,662,083 - 11,664,112 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0713,537,577 - 13,539,606 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0711,404,118 - 11,406,147 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0711,646,283 - 11,648,338 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl711,646,269 - 11,648,322 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0711,813,536 - 11,815,569 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4710,289,073 - 10,291,102 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1710,289,072 - 10,291,102 (-)NCBI
Celera76,964,215 - 6,966,244 (-)NCBICelera
Cytogenetic Map7q11NCBI
GADD45B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38192,476,127 - 2,478,257 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl192,476,122 - 2,478,805 (+)EnsemblGRCh38hg38GRCh38
GRCh37192,476,125 - 2,478,255 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36192,427,135 - 2,429,257 (+)NCBINCBI36Build 36hg18NCBI36
Build 34192,427,256 - 2,429,255NCBI
Celera192,413,616 - 2,415,750 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef192,247,727 - 2,249,861 (+)NCBIHuRef
CHM1_1192,475,705 - 2,477,840 (+)NCBICHM1_1
T2T-CHM13v2.0192,451,914 - 2,454,045 (+)NCBIT2T-CHM13v2.0
Gadd45b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391080,765,925 - 80,768,038 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1080,765,907 - 80,768,038 (+)EnsemblGRCm39 Ensembl
GRCm381080,930,091 - 80,932,204 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1080,930,073 - 80,932,204 (+)EnsemblGRCm38mm10GRCm38
MGSCv371080,392,836 - 80,394,949 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361080,333,220 - 80,335,333 (+)NCBIMGSCv36mm8
Celera1081,949,491 - 81,951,604 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Gadd45b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554954,864,868 - 4,867,658 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554954,864,932 - 4,866,728 (+)NCBIChiLan1.0ChiLan1.0
GADD45B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2206,858,791 - 6,863,365 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1196,090,497 - 6,092,629 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0191,489,263 - 1,491,391 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1192,451,837 - 2,453,992 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl192,451,837 - 2,453,992 (+)Ensemblpanpan1.1panPan2
GADD45B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12056,627,915 - 56,629,960 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2056,628,485 - 56,629,730 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2056,423,662 - 56,425,720 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02057,360,968 - 57,363,023 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2057,361,502 - 57,363,100 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12056,413,407 - 56,415,463 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02056,898,545 - 56,900,597 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02057,098,808 - 57,100,864 (-)NCBIUU_Cfam_GSD_1.0
Gadd45b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118216,355,340 - 216,357,217 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365881,477,476 - 1,479,457 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365881,476,580 - 1,479,444 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GADD45B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl276,107,929 - 76,111,479 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1276,107,928 - 76,111,458 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2276,659,395 - 76,662,926 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GADD45B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.162,248,566 - 2,250,718 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl62,248,583 - 2,250,889 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660816,407,398 - 6,410,196 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gadd45b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248285,663,485 - 5,665,666 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248285,663,604 - 5,665,666 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Gadd45b
11 total Variants

Predicted Target Of
Summary Value
Count of predictions:70
Count of miRNA genes:60
Interacting mature miRNAs:66
Transcripts:ENSRNOT00000026871
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 13 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat

1 to 10 of 13 rows
UniSTS:546779  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.278,778,604 - 8,778,937 (+)MAPPERmRatBN7.2
Rnor_6.0711,646,884 - 11,647,216NCBIRnor6.0
Rnor_5.0711,814,137 - 11,814,469UniSTSRnor5.0
Celera76,964,816 - 6,965,148UniSTS
Cytogenetic Map7q11UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000026871   ⟹   ENSRNOP00000026871
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl78,778,007 - 8,780,046 (-)Ensembl
Rnor_6.0 Ensembl711,646,269 - 11,648,322 (-)Ensembl
RefSeq Acc Id: NM_001008321   ⟹   NP_001008322
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,428,689 - 9,430,718 (-)NCBI
mRatBN7.278,778,004 - 8,780,033 (-)NCBI
Rnor_6.0711,646,283 - 11,648,312 (-)NCBI
Rnor_5.0711,813,536 - 11,815,569 (-)NCBI
RGSC_v3.4710,289,073 - 10,291,102 (-)RGD
Celera76,964,215 - 6,966,244 (-)RGD
Sequence:
RefSeq Acc Id: XM_006240888   ⟹   XP_006240950
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,429,172 - 9,430,991 (-)NCBI
mRatBN7.278,778,004 - 8,780,306 (-)NCBI
Rnor_6.0711,646,283 - 11,648,338 (-)NCBI
Rnor_5.0711,813,536 - 11,815,569 (-)NCBI
Sequence:
Protein RefSeqs NP_001008322 (Get FASTA)   NCBI Sequence Viewer  
  XP_006240950 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH85337 (Get FASTA)   NCBI Sequence Viewer  
  EDL89208 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000026871
  ENSRNOP00000026871.2
RefSeq Acc Id: NP_001008322   ⟸   NM_001008321
- UniProtKB: Q5U3Z2 (UniProtKB/TrEMBL),   F7FLQ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240950   ⟸   XM_006240888
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000026871   ⟸   ENSRNOT00000026871
Ribosomal protein eL8/eL30/eS12/Gadd45

Name Modeler Protein Id AA Range Protein Structure
AF-Q5U3Z2-F1-model_v2 AlphaFold Q5U3Z2 1-160 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13694995
Promoter ID:EPDNEW_R5520
Type:single initiation site
Name:Gadd45b_1
Description:growth arrest and DNA-damage-inducible, beta
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0711,648,321 - 11,648,381EPDNEW


1 to 20 of 20 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-34980 BioCyc
Ensembl Genes ENSRNOG00000019822 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000026871 ENTREZGENE
  ENSRNOT00000026871.5 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1330.30 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7302492 IMAGE-MGC_LOAD
InterPro GADD45 UniProtKB/TrEMBL
  L30e-like UniProtKB/TrEMBL
  Ribosomal_L7Ae/L30e/S12e/Gad45 UniProtKB/TrEMBL
KEGG Report rno:299626 UniProtKB/TrEMBL
MGC_CLONE MGC:105966 IMAGE-MGC_LOAD
NCBI Gene 299626 ENTREZGENE
PANTHER GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 BETA UniProtKB/TrEMBL
  PTHR10411 UniProtKB/TrEMBL
Pfam Ribosomal_L7Ae UniProtKB/TrEMBL
PhenoGen Gadd45b PhenoGen
RatGTEx ENSRNOG00000019822 RatGTEx
Superfamily-SCOP SSF55315 UniProtKB/TrEMBL
UniProt F7FLQ8 ENTREZGENE, UniProtKB/TrEMBL
  Q5U3Z2 ENTREZGENE, UniProtKB/TrEMBL
1 to 20 of 20 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-11-14 Gadd45b  growth arrest and DNA-damage-inducible, beta  Gadd45b  growth arrest and DNA-damage-inducible 45 beta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Gadd45b  growth arrest and DNA-damage-inducible 45 beta  Gadd45b_predicted  growth arrest and DNA-damage-inducible 45 beta (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Gadd45b_predicted  growth arrest and DNA-damage-inducible 45 beta (predicted)      Symbol and Name status set to approved 70820 APPROVED