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Gene: Gadd45b (growth arrest and DNA-damage-inducible 45 beta) Mus musculus
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Symbol: Gadd45b
Name: growth arrest and DNA-damage-inducible 45 beta
Description: Involved in activation of MAPKK activity; negative regulation of protein kinase activity; and regulation of cell cycle. Predicted to localize to the cytoplasm and nucleus. Is expressed in several structures, including arterial system; forelimb bud; future brain; sensory organ; and somite. Orthologous to human GADD45B (growth arrest and DNA damage inducible beta); PARTICIPATES IN interleukin-12 signaling pathway; p38 MAPK signaling pathway; cell cycle pathway, mitotic; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: AI323528; growth arrest and DNA damage-inducible protein GADD45 beta; growth arrest and DNA-damage-inducible protein GADD45 beta; Myd118; myeloid differentiation primary response gene 118; myeloid differentiation primary response protein MyD118; negative growth regulatory protein MyD118
Orthologs:
Homo sapiens (human) : GADD45B (growth arrest and DNA damage inducible beta)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gadd45b (growth arrest and DNA-damage-inducible, beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gadd45b (growth arrest and DNA damage inducible beta)
Pan paniscus (bonobo/pygmy chimpanzee) : GADD45B (growth arrest and DNA damage inducible beta)
Canis lupus familiaris (dog) : GADD45B (growth arrest and DNA damage inducible beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gadd45b (growth arrest and DNA damage inducible beta)
Sus scrofa (pig) : GADD45B (growth arrest and DNA damage inducible beta)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381080,930,091 - 80,932,204 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371080,392,836 - 80,394,949 (+)NCBIGRCm37mm9NCBIm37
MGSCv361080,333,220 - 80,335,333 (+)NCBImm8
Celera1081,949,491 - 81,951,604 (+)NCBICelera
Cytogenetic Map10 C1NCBI
cM Map1039.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Gadd45b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319221
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-17
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.