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Gene: Gadd45b (growth arrest and DNA-damage-inducible 45 beta) Mus musculus
Symbol: Gadd45b
Name: growth arrest and DNA-damage-inducible 45 beta
Description: Involved in activation of MAPKK activity; negative regulation of protein kinase activity; and regulation of cell cycle. Predicted to localize to the cytoplasm and nucleus. Is expressed in several structures, including arterial system; forelimb bud; future brain; sensory organ; and somite. Orthologous to human GADD45B (growth arrest and DNA damage inducible beta); PARTICIPATES IN interleukin-12 signaling pathway; p38 MAPK signaling pathway; cell cycle pathway, mitotic; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
Also known as: AI323528; growth arrest and DNA damage-inducible protein GADD45 beta; growth arrest and DNA-damage-inducible protein GADD45 beta; Myd118; myeloid differentiation primary response gene 118; myeloid differentiation primary response protein MyD118; negative growth regulatory protein MyD118
Homo sapiens (human) : GADD45B (growth arrest and DNA damage inducible beta)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gadd45b (growth arrest and DNA-damage-inducible, beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gadd45b (growth arrest and DNA damage inducible beta)
Pan paniscus (bonobo/pygmy chimpanzee) : GADD45B (growth arrest and DNA damage inducible beta)
Canis lupus familiaris (dog) : GADD45B (growth arrest and DNA damage inducible beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gadd45b (growth arrest and DNA damage inducible beta)
Sus scrofa (pig) : GADD45B (growth arrest and DNA damage inducible beta)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381080,930,091 - 80,932,204 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371080,392,836 - 80,394,949 (+)NCBIGRCm37mm9NCBIm37
MGSCv361080,333,220 - 80,335,333 (+)NCBImm8
Celera1081,949,491 - 81,951,604 (+)NCBICelera
Cytogenetic Map10 C1NCBI
cM Map1039.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Gadd45b
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319221
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-17
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.