Gene: Arhgef25 (Rho guanine nucleotide exchange factor 25) Rattus norvegicus
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Symbol: Arhgef25
Name: Rho guanine nucleotide exchange factor 25
Description: ENCODES a protein that exhibits Rho guanyl-nucleotide exchange factor activity (inferred); INVOLVED IN regulation of Rho protein signal transduction (inferred); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN myofibril (ortholog); plasma membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Geft; guanine nucleotide exchange factor GEFT; MGC72605; RAC/CDC42 exchange factor; rac/Cdc42/Rho exchange factor GEFT; Rho guanine nucleotide exchange factor (GEF) 25; RhoA/RAC/CDC42 exchange factor; rhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT
Orthologs:
Homo sapiens (human) : ARHGEF25 (Rho guanine nucleotide exchange factor 25)  HGNC  Alliance
Mus musculus (house mouse) : Arhgef25 (Rho guanine nucleotide exchange factor (GEF) 25)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arhgef25 (Rho guanine nucleotide exchange factor 25)
Pan paniscus (bonobo/pygmy chimpanzee) : ARHGEF25 (Rho guanine nucleotide exchange factor 25)
Canis lupus familiaris (dog) : ARHGEF25 (Rho guanine nucleotide exchange factor 25)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arhgef25 (Rho guanine nucleotide exchange factor 25)
Sus scrofa (pig) : ARHGEF25 (Rho guanine nucleotide exchange factor 25)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0770,469,304 - 70,476,633 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0770,646,945 - 70,654,051 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4767,137,452 - 67,144,481 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1767,158,181 - 67,165,211 (-)NCBI
Celera760,147,432 - 60,154,538 (-)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Arhgef25
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735210
Created: 2004-02-05
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE