1,2-dimethylhydrazine multiple interactions ISO RGD:1313753 6480464 Folic Acid inhibits the reaction [1, 2-Dimethylhydrazine results in increased expression of TBK1 mRNA] CTD PMID:22206623 1,2-dimethylhydrazine increases expression ISO RGD:1313753 6480464 1, 2-Dimethylhydrazine results in increased expression of TBK1 mRNA CTD PMID:22206623 17alpha-ethynylestradiol affects expression ISO RGD:1313753 6480464 Ethinyl Estradiol affects the expression of TBK1 mRNA CTD PMID:17555576 17alpha-ethynylestradiol multiple interactions ISO RGD:1313753 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TBK1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression ISO RGD:1313753 6480464 Ethinyl Estradiol results in increased expression of TBK1 mRNA CTD PMID:17942748 2,3',4,4',5-Pentachlorobiphenyl increases expression ISO RGD:1313753 6480464 2 more ... CTD PMID:31388691 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1313753 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TBK1 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of TBK1 mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of TBK1 mRNA CTD PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1313753 6480464 Tetrachlorodibenzodioxin affects the expression of TBK1 mRNA CTD PMID:21570461 , PMID:24680724 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1313753 6480464 Tetrachlorodibenzodioxin results in increased expression of TBK1 mRNA CTD PMID:17942748 3,4-methylenedioxymethamphetamine increases methylation ISO RGD:1313753 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased methylation of TBK1 promoter CTD PMID:26251327 3,4-methylenedioxymethamphetamine decreases expression ISO RGD:1313753 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of TBK1 mRNA CTD PMID:26251327 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1, 2-dithiol-3-thione results in decreased expression of TBK1 mRNA CTD PMID:19162173 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of TBK1 mRNA CTD PMID:24780913 acrolein multiple interactions ISO RGD:1313752 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TBK1 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of TBK1 mRNA CTD PMID:32699268 acrylamide increases expression ISO RGD:1313752 6480464 Acrylamide results in increased expression of TBK1 mRNA CTD PMID:32763439 aflatoxin B1 increases expression ISO RGD:1313753 6480464 Aflatoxin B1 results in increased expression of TBK1 mRNA CTD PMID:19770486 all-trans-retinoic acid increases expression ISO RGD:1313752 6480464 Tretinoin results in increased expression of TBK1 mRNA CTD PMID:33167477 alpha-pinene multiple interactions ISO RGD:1313752 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TBK1 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of TBK1 mRNA CTD PMID:32699268 amlexanox multiple interactions ISO RGD:1313753 6480464 amlexanox inhibits the reaction [Acetaminophen results in increased phosphorylation of TBK1 protein] more ... CTD PMID:31697998 more ... amlexanox decreases phosphorylation ISO RGD:1313753 6480464 amlexanox results in decreased phosphorylation of TBK1 protein CTD PMID:31697998 amlexanox decreases activity ISO RGD:1313752 6480464 amlexanox results in decreased activity of TBK1 protein CTD PMID:25321315 aristolochic acid A decreases expression ISO RGD:1313752 6480464 aristolochic acid I results in decreased expression of TBK1 mRNA CTD PMID:33212167 auranofin multiple interactions ISO RGD:1313753 6480464 Auranofin inhibits the reaction [TBK1 protein results in increased activity of IRF3 protein] CTD PMID:17034761 bafilomycin A1 multiple interactions ISO RGD:1313753 6480464 bafilomycin A1 promotes the reaction [Lipopolysaccharides results in increased phosphorylation of TBK1 protein], bafilomycin A1 promotes the reaction [Poly I-C results in increased phosphorylation of TBK1 protein] CTD PMID:25780039 benzo[a]pyrene increases expression ISO RGD:1313753 6480464 Benzo(a)pyrene results in increased expression of TBK1 mRNA CTD PMID:22228805 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:1313752 6480464 7 more ... CTD PMID:19150397 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of TBK1 mRNA CTD PMID:25181051 bisphenol A decreases expression ISO RGD:1313753 6480464 bisphenol A results in decreased expression of TBK1 mRNA CTD PMID:33221593 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of TBK1 mRNA CTD PMID:30816183 , PMID:32528016 caffeine increases phosphorylation ISO RGD:1313752 6480464 Caffeine results in increased phosphorylation of TBK1 protein CTD PMID:35688186 chromium(6+) affects expression ISO RGD:1313753 6480464 chromium hexavalent ion affects the expression of TBK1 mRNA CTD PMID:28472532 chrysin decreases activity ISO RGD:1313752 6480464 chrysin results in decreased activity of TBK1 protein CTD PMID:19426678 cisplatin multiple interactions ISO RGD:1313753 6480464 4-methyl-N1-(3-phenylpropyl)benzene-1, 2-diamine inhibits the reaction [Cisplatin results in increased expression of TBK1 mRNA] CTD PMID:26546572 cisplatin increases expression ISO RGD:1313753 6480464 Cisplatin results in increased expression of TBK1 mRNA CTD PMID:26546572 clofibrate decreases expression ISO RGD:1313753 6480464 Clofibrate results in decreased expression of TBK1 mRNA CTD PMID:17585979 copper(II) sulfate increases expression ISO RGD:1313752 6480464 Copper Sulfate results in increased expression of TBK1 mRNA CTD PMID:19549813 curcumin multiple interactions ISO RGD:1313752 6480464 Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of TBK1 mRNA] CTD PMID:23452621 cyclosporin A increases expression ISO RGD:1313752 6480464 Cyclosporine results in increased expression of TBK1 mRNA CTD PMID:25562108 dicrotophos decreases expression ISO RGD:1313752 6480464 dicrotophos results in decreased expression of TBK1 mRNA CTD PMID:28302478 dioxygen multiple interactions ISO RGD:1313752 6480464 3 more ... CTD PMID:23452621 dioxygen increases expression ISO RGD:1313752 6480464 Oxygen deficiency results in increased expression of TBK1 mRNA CTD PMID:23452621 disodium selenite multiple interactions ISO RGD:1313753 6480464 Sodium Selenite inhibits the reaction [TBK1 protein results in increased activity of IRF3 protein] CTD PMID:18279804 eriodictyol decreases activity ISO RGD:1313752 6480464 eriodictyol results in decreased activity of TBK1 protein CTD PMID:19426678 ethyl methanesulfonate increases expression ISO RGD:1313752 6480464 Ethyl Methanesulfonate results in increased expression of TBK1 mRNA CTD PMID:23649840 fenthion decreases expression ISO RGD:1313753 6480464 Fenthion results in decreased expression of TBK1 mRNA CTD PMID:34813904 flutamide increases expression EXP 6480464 Flutamide results in increased expression of TBK1 mRNA CTD PMID:24136188 folic acid multiple interactions ISO RGD:1313753 6480464 Folic Acid inhibits the reaction [1, 2-Dimethylhydrazine results in increased expression of TBK1 mRNA] CTD PMID:22206623 formaldehyde decreases expression ISO RGD:1313752 6480464 Formaldehyde results in decreased expression of TBK1 mRNA CTD PMID:20655997 genistein multiple interactions ISO RGD:1313752 6480464 Genistein inhibits the reaction [Oxygen deficiency results in increased expression of TBK1 mRNA] CTD PMID:23452621 genistein increases methylation EXP 6480464 Genistein results in increased methylation of TBK1 gene CTD PMID:28505145 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of TBK1 mRNA CTD PMID:22061828 glyphosate decreases expression ISO RGD:1313752 6480464 glyphosate results in decreased expression of TBK1 mRNA CTD PMID:31295307 graphene oxide increases expression ISO RGD:1313753 6480464 graphene oxide results in increased expression of TBK1 mRNA CTD PMID:33227293 hexadecanoic acid increases phosphorylation ISO RGD:1313753 6480464 Palmitic Acid results in increased phosphorylation of TBK1 protein CTD PMID:32905826 hexadecanoic acid multiple interactions ISO RGD:1313753 6480464 amlexanox inhibits the reaction [Palmitic Acid results in increased phosphorylation of TBK1 protein] CTD PMID:32905826 isoprenaline increases expression ISO RGD:1313753 6480464 Isoproterenol results in increased expression of TBK1 mRNA CTD PMID:20003209 isoprenaline multiple interactions EXP 6480464 [Isoproterenol co-treated with POSTN protein] results in decreased expression of TBK1 mRNA CTD PMID:30303030 ivermectin decreases expression ISO RGD:1313752 6480464 Ivermectin results in decreased expression of TBK1 protein CTD PMID:32959892 lipopolysaccharide increases response to substance ISO RGD:1313752 6480464 TBK1 protein results in increased susceptibility to Lipopolysaccharides CTD PMID:21904615 lipopolysaccharide increases phosphorylation ISO RGD:1313753 6480464 Lipopolysaccharides results in increased phosphorylation of TBK1 protein CTD PMID:25780039 lipopolysaccharide multiple interactions ISO RGD:1313753 6480464 APPL1 protein promotes the reaction [Lipopolysaccharides results in increased phosphorylation of TBK1 protein] more ... CTD PMID:25780039 luteolin decreases activity ISO RGD:1313752 6480464 Luteolin results in decreased activity of TBK1 protein CTD PMID:19426678 mangiferin decreases expression ISO RGD:1313753 6480464 mangiferin results in decreased expression of TBK1 mRNA CTD PMID:15135318 methyl methanesulfonate increases expression ISO RGD:1313752 6480464 Methyl Methanesulfonate results in increased expression of TBK1 mRNA CTD PMID:23649840 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of TBK1 mRNA CTD PMID:24136188 o-anisidine decreases expression ISO RGD:1313752 6480464 2-anisidine results in decreased expression of TBK1 mRNA CTD PMID:28089782 oxybenzone increases expression ISO RGD:1313752 6480464 oxybenzone results in increased expression of TBK1 mRNA CTD PMID:36581016 ozone multiple interactions ISO RGD:1313752 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TBK1 mRNA more ... CTD PMID:32699268 paracetamol affects expression ISO RGD:1313753 6480464 Acetaminophen affects the expression of TBK1 mRNA CTD PMID:17562736 paracetamol increases phosphorylation ISO RGD:1313753 6480464 Acetaminophen results in increased phosphorylation of TBK1 protein CTD PMID:31697998 paracetamol multiple interactions ISO RGD:1313753 6480464 [vadimezan affects the reaction [P2RX1 protein affects the susceptibility to Acetaminophen]] which affects the phosphorylation of TBK1 protein, amlexanox inhibits the reaction [Acetaminophen results in increased phosphorylation of TBK1 protein] CTD PMID:31697998 , PMID:37046119 paracetamol decreases expression ISO RGD:1313752 6480464 Acetaminophen results in decreased expression of TBK1 mRNA CTD PMID:27761495 paraquat increases phosphorylation ISO RGD:1313753 6480464 Paraquat results in increased phosphorylation of TBK1 protein CTD PMID:32763286 paraquat multiple interactions ISO RGD:1313753 6480464 amlexanox inhibits the reaction [Paraquat results in increased phosphorylation of TBK1 protein] CTD PMID:32763286 pentachlorophenol increases expression ISO RGD:1313753 6480464 Pentachlorophenol results in increased expression of TBK1 mRNA CTD PMID:23892564 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:1313752 6480464 perfluorooctane sulfonic acid results in decreased expression of TBK1 mRNA CTD PMID:27153767 Phytolaccoside E increases phosphorylation ISO RGD:1313752 6480464 esculentoside A results in increased phosphorylation of TBK1 protein CTD PMID:36460195 poly(I:C) increases phosphorylation ISO RGD:1313753 6480464 Poly I-C results in increased phosphorylation of TBK1 protein CTD PMID:25780039 poly(I:C) multiple interactions ISO RGD:1313753 6480464 APPL1 protein promotes the reaction [Poly I-C results in increased phosphorylation of TBK1 protein], bafilomycin A1 promotes the reaction [Poly I-C results in increased phosphorylation of TBK1 protein] CTD PMID:25780039 propiconazole increases expression ISO RGD:1313753 6480464 propiconazole results in increased expression of TBK1 mRNA CTD PMID:21278054 quercetin decreases activity ISO RGD:1313752 6480464 Quercetin results in decreased activity of TBK1 protein CTD PMID:19426678 resveratrol multiple interactions ISO RGD:1313753 6480464 resveratrol inhibits the reaction [TBK1 protein results in increased activity of IRF3 protein], resveratrol inhibits the reaction [TBK1 protein results in increased phosphorylation of IRF3 protein] CTD PMID:16116226 , PMID:16678799 resveratrol multiple interactions ISO RGD:1313752 6480464 resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of TBK1 mRNA] CTD PMID:23452621 sodium arsenite increases expression ISO RGD:1313753 6480464 sodium arsenite results in increased expression of TBK1 mRNA CTD PMID:19822182 sulindac increases expression ISO RGD:1313752 6480464 Sulindac results in increased expression of TBK1 mRNA CTD PMID:11093808 tamoxifen affects expression ISO RGD:1313753 6480464 Tamoxifen affects the expression of TBK1 mRNA CTD PMID:17555576 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of TBK1 mRNA CTD PMID:34492290 Triptolide increases expression ISO RGD:1313753 6480464 triptolide results in increased expression of TBK1 mRNA, triptolide results in increased expression of TBK1 protein CTD PMID:36520315 tunicamycin decreases expression ISO RGD:1313753 6480464 Tunicamycin results in decreased expression of TBK1 mRNA CTD PMID:17127020 tunicamycin decreases expression ISO RGD:1313752 6480464 Tunicamycin results in decreased expression of TBK1 mRNA CTD PMID:29453283 vadimezan multiple interactions ISO RGD:1313753 6480464 [vadimezan affects the reaction [P2RX1 protein affects the susceptibility to Acetaminophen]] which affects the phosphorylation of TBK1 protein CTD PMID:37046119
