Tbk1 (TANK binding kinase 1) - Rat Genome Database

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Gene: Tbk1 (TANK binding kinase 1) Ictidomys tridecemlineatus
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Symbol: Tbk1
Name: TANK binding kinase 1
RGD ID: 12621496
Description: ENCODES a protein that exhibits identical protein binding (ortholog); nucleic acid binding (ortholog); phosphoprotein binding (ortholog); INVOLVED IN activation of innate immune response (ortholog); defense response to Gram-positive bacterium (ortholog); dendritic cell proliferation (ortholog); PARTICIPATES IN Toll-like receptor signaling pathway; ASSOCIATED WITH ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED (HERPES-SPECIFIC), 8 (ortholog); frontotemporal dementia and/or amyotrophic lateral sclerosis-4 (ortholog); Glaucoma 1, Open Angle, P (ortholog); FOUND IN cytoplasm (ortholog); intracellular membrane-bounded organelle (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: serine/threonine-protein kinase TBK1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494551,300,898 - 51,346,375 (-)NCBI
SpeTri2.0NW_0049365452,763,755 - 2,809,229 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Tbk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494551,300,898 - 51,346,375 (-)NCBI
SpeTri2.0NW_0049365452,763,755 - 2,809,229 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1264,452,090 - 64,502,114 (+)EnsemblGRCh38hg38GRCh38
GRCh381264,452,105 - 64,502,114 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371264,845,900 - 64,895,894 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361263,132,204 - 63,182,158 (+)NCBINCBI36hg18NCBI36
Build 341263,132,203 - 63,182,158NCBI
Celera1264,510,375 - 64,560,181 (+)NCBI
Cytogenetic Map12q14.2NCBI
HuRef1261,898,186 - 61,948,226 (+)NCBIHuRef
CHM1_11264,812,935 - 64,863,007 (+)NCBICHM1_1
Tbk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910121,382,360 - 121,422,699 (-)NCBIGRCm39mm39
GRCm39 Ensembl10121,382,360 - 121,422,692 (-)Ensembl
GRCm3810121,546,455 - 121,586,794 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10121,546,455 - 121,586,787 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710120,983,511 - 121,023,850 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610120,949,520 - 120,989,807 (-)NCBImm8
Celera10123,931,313 - 123,970,044 (-)NCBICelera
Cytogenetic Map10D2NCBI
Tbk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2757,077,830 - 57,110,868 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl763,655,247 - 63,687,978 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0763,655,247 - 63,687,978 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0763,877,567 - 63,910,298 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4760,863,099 - 60,896,131 (-)NCBIRGSC3.4rn4RGSC3.4
Celera753,819,361 - 53,852,262 (-)NCBICelera
Cytogenetic Map7q22NCBI
Tbk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545811,211,398 - 11,263,867 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545811,210,120 - 11,263,632 (+)NCBIChiLan1.0ChiLan1.0
TBK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11224,919,412 - 24,968,587 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1224,917,246 - 24,968,587 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01224,419,271 - 24,469,164 (-)NCBIMhudiblu_PPA_v0panPan3
TBK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1107,169,664 - 7,208,890 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl107,168,007 - 7,208,899 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha107,102,668 - 7,144,367 (+)NCBI
ROS_Cfam_1.0107,276,927 - 7,318,803 (+)NCBI
UMICH_Zoey_3.1107,142,851 - 7,184,688 (+)NCBI
UNSW_CanFamBas_1.0107,395,493 - 7,437,313 (+)NCBI
UU_Cfam_GSD_1.0107,526,057 - 7,567,705 (+)NCBI
TBK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl528,828,568 - 28,929,964 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1528,880,210 - 28,929,964 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TBK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11160,136,162 - 60,182,354 (+)NCBI
ChlSab1.1 Ensembl1160,136,232 - 60,182,344 (+)Ensembl
Vero_WHO_p1.0NW_023666037185,623,292 - 185,669,524 (-)NCBI
Tbk1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248023,861,821 - 3,914,061 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005328694   ⟹   XP_005328751
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494551,300,906 - 51,346,375 (-)NCBI
SpeTri2.0NW_0049365452,763,755 - 2,809,229 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040280378   ⟹   XP_040136312
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494551,300,898 - 51,346,375 (-)NCBI
Protein Sequences
Protein RefSeqs XP_005328751 (Get FASTA)   NCBI Sequence Viewer  
  XP_040136312 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3291451 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005328751   ⟸   XM_005328694
- Peptide Label: isoform X1
- UniProtKB: I3MBE7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040136312   ⟸   XM_040280378
- Peptide Label: isoform X2
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000008299 ENTREZGENE
Ensembl Protein ENSSTOP00000007452 ENTREZGENE
NCBI Gene Tbk1 ENTREZGENE
UniProt I3MBE7 ENTREZGENE