Cct2 (chaperonin containing TCP1 subunit 2) - Rat Genome Database

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Gene: Cct2 (chaperonin containing TCP1 subunit 2) Rattus norvegicus
Analyze
Symbol: Cct2
Name: chaperonin containing TCP1 subunit 2
RGD ID: 1359143
Description: Predicted to enable protein folding chaperone; ubiquitin protein ligase binding activity; and unfolded protein binding activity. Predicted to be involved in several processes, including chaperone mediated protein folding independent of cofactor; positive regulation of protein localization to Cajal body; and positive regulation of telomerase RNA localization to Cajal body. Predicted to act upstream of with a positive effect on scaRNA localization to Cajal body. Predicted to act upstream of or within binding activity of sperm to zona pellucida and chaperone-mediated protein complex assembly. Predicted to be located in cell body; cytosol; and microtubule. Predicted to be part of chaperonin-containing T-complex and zona pellucida receptor complex. Orthologous to human CCT2 (chaperonin containing TCP1 subunit 2); INTERACTS WITH (+)-schisandrin B; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CCT-beta; chaperonin containing TCP1, subunit 2 (beta); MGC94480; T-complex protein 1 subunit beta; TCP-1-beta
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8754,578,654 - 54,591,428 (-)NCBIGRCr8
mRatBN7.2752,692,725 - 52,705,478 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl752,692,725 - 52,706,944 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx754,599,478 - 54,612,221 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0756,802,584 - 56,815,327 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0756,580,484 - 56,593,227 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0760,106,532 - 60,122,779 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl760,109,974 - 60,122,805 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0760,106,598 - 60,122,867 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4756,391,341 - 56,404,084 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1756,412,071 - 56,424,814 (-)NCBI
Celera749,468,323 - 49,481,066 (-)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
1H-pyrazole  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
artesunate  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
ceruletide  (EXP)
chloropicrin  (ISO)
chromium(6+)  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
diarsenic trioxide  (ISO)
diazinon  (EXP)
dicrotophos  (ISO)
diethylstilbestrol  (EXP)
dioxygen  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
ethanol  (EXP,ISO)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
hyaluronic acid  (EXP)
hydralazine  (ISO)
hydrogen peroxide  (EXP,ISO)
ivermectin  (ISO)
lead(II) chloride  (ISO)
menadione  (ISO)
methamphetamine  (EXP)
methidathion  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosomorpholine  (EXP)
naphthalene  (ISO)
nefazodone  (EXP)
nickel dichloride  (EXP)
nimesulide  (EXP)
oxaliplatin  (EXP)
p-menthan-3-ol  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
PhIP  (EXP)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propiconazole  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trimellitic anhydride  (ISO)
triptonide  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. The chaperonin containing t-complex polypeptide 1 (TCP-1). Multisubunit machinery assisting in protein folding and assembly in the eukaryotic cytosol. Kubota H, etal., Eur J Biochem 1995 May 15;230(1):3-16.
4. Structures and co-regulated expression of the genes encoding mouse cytosolic chaperonin CCT subunits. Kubota H, etal., Eur J Biochem 1999 Jun;262(2):492-500.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:7828721   PMID:7953530   PMID:15489334   PMID:17634366   PMID:19056867   PMID:20080638   PMID:20193073   PMID:20458337   PMID:21525035   PMID:21753002   PMID:21880732   PMID:23011926  
PMID:23376485   PMID:23533145   PMID:23716698   PMID:23979707   PMID:24625528   PMID:25467444   PMID:29476059   PMID:31904090   PMID:33450132  


Genomics

Comparative Map Data
Cct2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8754,578,654 - 54,591,428 (-)NCBIGRCr8
mRatBN7.2752,692,725 - 52,705,478 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl752,692,725 - 52,706,944 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx754,599,478 - 54,612,221 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0756,802,584 - 56,815,327 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0756,580,484 - 56,593,227 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0760,106,532 - 60,122,779 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl760,109,974 - 60,122,805 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0760,106,598 - 60,122,867 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4756,391,341 - 56,404,084 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1756,412,071 - 56,424,814 (-)NCBI
Celera749,468,323 - 49,481,066 (-)NCBICelera
Cytogenetic Map7q22NCBI
CCT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381269,585,459 - 69,601,570 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1269,585,426 - 69,601,570 (+)EnsemblGRCh38hg38GRCh38
GRCh371269,979,239 - 69,995,350 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361268,265,475 - 68,281,624 (+)NCBINCBI36Build 36hg18NCBI36
Build 341268,265,474 - 68,281,624NCBI
Celera1269,642,857 - 69,659,010 (+)NCBICelera
Cytogenetic Map12q15NCBI
HuRef1267,028,675 - 67,044,820 (+)NCBIHuRef
CHM1_11269,947,631 - 69,963,780 (+)NCBICHM1_1
T2T-CHM13v2.01269,564,374 - 69,580,485 (+)NCBIT2T-CHM13v2.0
Cct2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910116,886,902 - 116,899,757 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10116,886,906 - 116,899,719 (-)EnsemblGRCm39 Ensembl
GRCm3810117,050,997 - 117,063,852 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10117,051,001 - 117,063,814 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710116,488,054 - 116,500,870 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610116,455,109 - 116,467,875 (-)NCBIMGSCv36mm8
Celera10118,994,151 - 119,006,966 (-)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1065.07NCBI
Cct2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554059,892,116 - 9,904,407 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554059,892,089 - 9,904,407 (+)NCBIChiLan1.0ChiLan1.0
CCT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21077,617,597 - 77,633,554 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11277,613,995 - 77,629,952 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01267,113,221 - 67,128,159 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11269,883,710 - 69,898,671 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1269,883,710 - 69,898,671 (+)Ensemblpanpan1.1panPan2
CCT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11011,560,287 - 11,586,559 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1011,560,396 - 11,578,433 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1011,492,095 - 11,518,353 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01011,683,661 - 11,709,923 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1011,683,710 - 11,701,919 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11011,550,671 - 11,576,938 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01011,797,739 - 11,824,127 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01011,920,916 - 11,939,358 (+)NCBIUU_Cfam_GSD_1.0
Cct2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494546,673,102 - 46,693,918 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365457,415,753 - 7,439,800 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365457,416,257 - 7,436,024 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl533,858,572 - 33,873,523 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1533,858,514 - 33,873,596 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2536,457,610 - 36,471,587 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CCT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11165,213,992 - 65,230,318 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1165,214,060 - 65,230,379 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037180,459,300 - 180,475,791 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cct2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475028,198,475 - 28,217,158 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475028,202,524 - 28,217,223 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cct2
35 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:28
Count of miRNA genes:25
Interacting mature miRNAs:25
Transcripts:ENSRNOT00000037946
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
10059605Kidm47Kidney mass QTL 472.910.05kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)74725178365728867Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73796056982960569Rat
2293685Bmd21Bone mineral density QTL 214.20.0003femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)74765143992651439Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73111283276112832Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
1354639Spl5Serum phospholipid level QTL 53.9blood LDL phospholipid amount (VT:0010505)blood low density lipoprotein phospholipid level (CMO:0001568)71965431752888450Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)74278731487787314Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat
2293696Bmd32Bone mineral density QTL 325.10.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)74765143992651439Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73429328279293282Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74659007091590070Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73429328279293282Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
2293707Bss32Bone structure and strength QTL 327.640.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)74765143992651439Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
2303629Vencon3Ventilatory control QTL 37.25respiration trait (VT:0001943)respiration rate (CMO:0000289)74110969256793354Rat
2293644Bmd29Bone mineral density QTL 295.40.0001femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)74765143992651439Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72673740163902784Rat
2300178Bmd54Bone mineral density QTL 545.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)74765143992651439Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)72940968353612950Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)72940968374409683Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat

Markers in Region
WI-19751  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2752,692,750 - 52,693,004 (+)MAPPERmRatBN7.2
Rnor_6.0760,110,004 - 60,110,257NCBIRnor6.0
Rnor_6.0760,104,727 - 60,104,979NCBIRnor6.0
Rnor_5.0760,104,791 - 60,105,043UniSTSRnor5.0
Rnor_5.0760,110,093 - 60,110,346UniSTSRnor5.0
RGSC_v3.4756,391,359 - 56,391,612UniSTSRGSC3.4
Celera749,468,341 - 49,468,594UniSTS
Cytogenetic Map7q22UniSTS
RH143421  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2752,698,560 - 52,699,325 (+)MAPPERmRatBN7.2
Rnor_6.0760,115,813 - 60,116,577NCBIRnor6.0
Rnor_5.0760,115,902 - 60,116,666UniSTSRnor5.0
RGSC_v3.4756,397,168 - 56,397,932UniSTSRGSC3.4
Celera749,474,150 - 49,474,914UniSTS
RH 3.4 Map7483.0UniSTS
Cytogenetic Map7q22UniSTS
MARC_36444-36445:1067884409:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2752,696,386 - 52,697,244 (+)MAPPERmRatBN7.2
Rnor_6.0760,113,639 - 60,114,496NCBIRnor6.0
Rnor_5.0760,113,728 - 60,114,585UniSTSRnor5.0
RGSC_v3.4756,394,994 - 56,395,851UniSTSRGSC3.4
Celera749,471,976 - 49,472,833UniSTS
Cytogenetic Map7q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000037946   ⟹   ENSRNOP00000029234
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl752,692,725 - 52,705,517 (-)Ensembl
Rnor_6.0 Ensembl760,109,974 - 60,122,805 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096174   ⟹   ENSRNOP00000086312
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl752,694,571 - 52,704,832 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113939   ⟹   ENSRNOP00000095994
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl752,692,725 - 52,706,944 (-)Ensembl
RefSeq Acc Id: NM_001005905   ⟹   NP_001005905
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8754,578,662 - 54,591,405 (-)NCBI
mRatBN7.2752,692,733 - 52,705,478 (-)NCBI
Rnor_6.0760,109,986 - 60,122,729 (-)NCBI
Rnor_5.0760,106,598 - 60,122,867 (-)NCBI
RGSC_v3.4756,391,341 - 56,404,084 (-)RGD
Celera749,468,323 - 49,481,066 (-)RGD
Sequence:
RefSeq Acc Id: XM_039078736   ⟹   XP_038934664
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8754,578,654 - 54,591,428 (-)NCBI
mRatBN7.2752,692,725 - 52,705,441 (-)NCBI
RefSeq Acc Id: NP_001005905   ⟸   NM_001005905
- UniProtKB: Q5XIM9 (UniProtKB/Swiss-Prot),   A6IGR4 (UniProtKB/TrEMBL),   A0A8I6GLE7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000029234   ⟸   ENSRNOT00000037946
RefSeq Acc Id: XP_038934664   ⟸   XM_039078736
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GLE7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000086312   ⟸   ENSRNOT00000096174
Ensembl Acc Id: ENSRNOP00000095994   ⟸   ENSRNOT00000113939

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XIM9-F1-model_v2 AlphaFold Q5XIM9 1-535 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695207
Promoter ID:EPDNEW_R5732
Type:multiple initiation site
Name:Cct2_1
Description:chaperonin containing TCP1 subunit 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0760,122,757 - 60,122,817EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359143 AgrOrtholog
BioCyc Gene G2FUF-34016 BioCyc
Ensembl Genes ENSRNOG00000021317 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055012838 UniProtKB/Swiss-Prot
  ENSRNOG00060009370 UniProtKB/Swiss-Prot
  ENSRNOG00065012929 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000037946.6 UniProtKB/Swiss-Prot
  ENSRNOT00000096174.1 UniProtKB/TrEMBL
  ENSRNOT00000113939.1 UniProtKB/TrEMBL
  ENSRNOT00055021966 UniProtKB/Swiss-Prot
  ENSRNOT00060015872 UniProtKB/Swiss-Prot
  ENSRNOT00065021177 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.560.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.260.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.50.7.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7135109 IMAGE-MGC_LOAD
InterPro Chap_CCT_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chaperone_TCP-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chaperonin_TCP-1_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cpn60/GroEL/TCP-1 UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
  GroEL-like_apical_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GROEL-like_equatorial_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TCP-1-like_intermed_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TCP-1_chaperonin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:299809 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:94480 IMAGE-MGC_LOAD
NCBI Gene 299809 ENTREZGENE
PANTHER PTHR11353 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11353:SF23 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Cpn60_TCP1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cct2 PhenoGen
PRINTS TCOMPLEXTCP1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TCP1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TCP1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TCP1_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000021317 RatGTEx
  ENSRNOG00055012838 RatGTEx
  ENSRNOG00060009370 RatGTEx
  ENSRNOG00065012929 RatGTEx
Superfamily-SCOP SSF48592 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52029 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54849 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A5L3_RAT UniProtKB/TrEMBL
  A0A8I6GLE7 ENTREZGENE, UniProtKB/TrEMBL
  A6IGR4 ENTREZGENE, UniProtKB/TrEMBL
  Q5XIM9 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-13 Cct2  chaperonin containing TCP1 subunit 2  Cct2  chaperonin containing TCP1, subunit 2 (beta)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Cct2  chaperonin containing TCP1, subunit 2 (beta)      Symbol and Name status set to approved 1299863 APPROVED
2005-07-29 Cct2  chaperonin containing TCP1, subunit 2 (beta)      Symbol and Name status set to provisional 70820 PROVISIONAL