CCT2 (chaperonin containing TCP1 subunit 2) - Rat Genome Database

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Gene: CCT2 (chaperonin containing TCP1 subunit 2) Chlorocebus sabaeus
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Symbol: CCT2
Name: chaperonin containing TCP1 subunit 2
RGD ID: 18692060
Description: ENCODES a protein that exhibits ubiquitin protein ligase binding (ortholog); INVOLVED IN binding of sperm to zona pellucida (ortholog); chaperone mediated protein folding independent of cofactor (ortholog); chaperone-mediated protein complex assembly (ortholog); ASSOCIATED WITH genetic disease (ortholog); osteoporosis (ortholog); FOUND IN cell body (ortholog); chaperonin-containing T-complex (ortholog); microtubule (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: T-complex protein 1 subunit beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11165,213,992 - 65,230,318 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1165,214,060 - 65,230,379 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037180,459,300 - 180,475,791 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CCT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11165,213,992 - 65,230,318 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1165,214,060 - 65,230,379 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037180,459,300 - 180,475,791 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CCT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381269,585,459 - 69,601,570 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1269,585,426 - 69,601,570 (+)EnsemblGRCh38hg38GRCh38
GRCh371269,979,239 - 69,995,350 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361268,265,475 - 68,281,624 (+)NCBINCBI36Build 36hg18NCBI36
Build 341268,265,474 - 68,281,624NCBI
Celera1269,642,857 - 69,659,010 (+)NCBICelera
Cytogenetic Map12q15NCBI
HuRef1267,028,675 - 67,044,820 (+)NCBIHuRef
CHM1_11269,947,631 - 69,963,780 (+)NCBICHM1_1
T2T-CHM13v2.01269,564,374 - 69,580,485 (+)NCBIT2T-CHM13v2.0
Cct2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910116,886,902 - 116,899,757 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10116,886,906 - 116,899,719 (-)EnsemblGRCm39 Ensembl
GRCm3810117,050,997 - 117,063,852 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10117,051,001 - 117,063,814 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710116,488,054 - 116,500,870 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610116,455,109 - 116,467,875 (-)NCBIMGSCv36mm8
Celera10118,994,151 - 119,006,966 (-)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1065.07NCBI
Cct2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8754,578,654 - 54,591,428 (-)NCBIGRCr8
mRatBN7.2752,692,725 - 52,705,478 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl752,692,725 - 52,706,944 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx754,599,478 - 54,612,221 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0756,802,584 - 56,815,327 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0756,580,484 - 56,593,227 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0760,106,532 - 60,122,779 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl760,109,974 - 60,122,805 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0760,106,598 - 60,122,867 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4756,391,341 - 56,404,084 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1756,412,071 - 56,424,814 (-)NCBI
Celera749,468,323 - 49,481,066 (-)NCBICelera
Cytogenetic Map7q22NCBI
Cct2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554059,892,116 - 9,904,407 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554059,892,089 - 9,904,407 (+)NCBIChiLan1.0ChiLan1.0
CCT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21077,617,597 - 77,633,554 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11277,613,995 - 77,629,952 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01267,113,221 - 67,128,159 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11269,883,710 - 69,898,671 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1269,883,710 - 69,898,671 (+)Ensemblpanpan1.1panPan2
CCT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11011,560,287 - 11,586,559 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1011,560,396 - 11,578,433 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1011,492,095 - 11,518,353 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01011,683,661 - 11,709,923 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1011,683,710 - 11,701,919 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11011,550,671 - 11,576,938 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01011,797,739 - 11,824,127 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01011,920,916 - 11,939,358 (+)NCBIUU_Cfam_GSD_1.0
Cct2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494546,673,102 - 46,693,918 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365457,415,753 - 7,439,800 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365457,416,257 - 7,436,024 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl533,858,572 - 33,873,523 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1533,858,514 - 33,873,596 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2536,457,610 - 36,471,587 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Cct2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475028,198,475 - 28,217,158 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475028,202,524 - 28,217,223 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 19 60
Low 1
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000002236   ⟹   ENSCSAP00000000564
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1165,214,060 - 65,230,379 (+)Ensembl
RefSeq Acc Id: XM_008003988   ⟹   XP_008002179
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11165,213,992 - 65,230,318 (+)NCBI
Vero_WHO_p1.0NW_023666037180,459,300 - 180,475,791 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008003989   ⟹   XP_008002180
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11165,214,506 - 65,230,318 (+)NCBI
Vero_WHO_p1.0NW_023666037180,459,300 - 180,475,369 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008002179 (Get FASTA)   NCBI Sequence Viewer  
  XP_008002180 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000000564.1
RefSeq Acc Id: XP_008002179   ⟸   XM_008003988
- Peptide Label: isoform X1
- UniProtKB: A0A0D9QW25 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008002180   ⟸   XM_008003989
- Peptide Label: isoform X2
RefSeq Acc Id: ENSCSAP00000000564   ⟸   ENSCSAT00000002236


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000004209 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000002236.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.560.10 UniProtKB/TrEMBL
  3.30.260.10 UniProtKB/TrEMBL
  3.50.7.10 UniProtKB/TrEMBL
InterPro Chap_CCT_beta UniProtKB/TrEMBL
  Chaperone_TCP-1 UniProtKB/TrEMBL
  Chaperonin_TCP-1_CS UniProtKB/TrEMBL
  Cpn60/TCP-1 UniProtKB/TrEMBL
  GroEL-like_apical_dom_sf UniProtKB/TrEMBL
  GROEL-like_equatorial_sf UniProtKB/TrEMBL
  TCP-1-like_intermed_sf UniProtKB/TrEMBL
NCBI Gene CCT2 ENTREZGENE
PANTHER PTHR11353 UniProtKB/TrEMBL
  PTHR11353:SF23 UniProtKB/TrEMBL
Pfam Cpn60_TCP1 UniProtKB/TrEMBL
PRINTS TCOMPLEXTCP1 UniProtKB/TrEMBL
PROSITE TCP1_1 UniProtKB/TrEMBL
  TCP1_2 UniProtKB/TrEMBL
  TCP1_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF48592 UniProtKB/TrEMBL
  SSF52029 UniProtKB/TrEMBL
  SSF54849 UniProtKB/TrEMBL
UniProt A0A0D9QW25 ENTREZGENE, UniProtKB/TrEMBL