Imported Annotations - MGI | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| autism spectrum disorder | ISS | RGD:736492 | 13592920 | MouseDO | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene-Chemical Interaction AnnotationsGene Ontology Annotations |
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Analyze GeneStrainQTL List |
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MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
Gene-Chemical Interaction AnnotationsGene Ontology AnnotationsDisease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Cellular Component
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Molecular Function
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References - curated| 1. | Boyken J, etal., Neuron. 2013 Apr 24;78(2):285-97. doi: 10.1016/j.neuron.2013.02.027. |
| 2. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 3. | GOA data from the GO Consortium |
| 4. | Hosaka M and Sudhof TC, J Biol Chem 1998 May 29;273(22):13371-4. |
| 5. | Jaffrey SR, etal., Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3199-204. Epub 2002 Feb 26. |
| 6. | Kao HT, etal., Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4667-72. |
| 7. | Lam PP, etal., Mol Biol Cell. 2007 Jul;18(7):2473-80. Epub 2007 Apr 18. |
| 8. | MGD data from the GO Consortium |
| 9. | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 10. | RGD automated data pipeline |
| 11. | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 12. | RGD automated import pipeline for gene-chemical interactions |
References - uncuratedGenomics
Comparative Map Data| Syn3 (Rattus norvegicus - Norway rat) |
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| SYN3 (Homo sapiens - human) |
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| Syn3 (Mus musculus - house mouse) |
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| Syn3 (Chinchilla lanigera - long-tailed chinchilla) |
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| SYN3 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| SYN3 (Canis lupus familiaris - dog) |
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| Syn3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| SYN3 (Sus scrofa - pig) |
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Position Markers| D7Mgh9 |
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| D7Rat40 |
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| D7Rat216 |
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| RH128273 |
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| RH129267 |
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| RH94615 |
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| RH143027 |
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| RH144261 |
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| BI278238 |
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| BF400160 |
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| RH135110 |
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| RH141014 |
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| Timp3 |
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| G45201 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| testis | heart | brain | ovary | uterus | skeletal muscle tissue | colon | gastrocnemius | forebrain | hindbrain | lung | spleen | liver | kidney | adrenal gland | thymus | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| High | ||||||||||||||||
| Medium | 10 | 26 | 21 | |||||||||||||
| Low | 22 | 35 | 13 | 15 | 4 | 1 | 3 | 2 | 4 | 11 | 10 | 16 | 35 | 8 | 8 | |
| Below cutoff | 8 | 2 | 6 | 1 | 25 |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_017109 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| GenBank Nucleotide | AABR07056404 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AABR07056405 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07056406 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07056407 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07056408 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07073290 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07073291 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047802 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047803 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047804 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047805 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047806 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047807 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047808 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047809 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047810 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047811 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047812 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047813 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047814 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047815 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047816 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047817 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047818 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047819 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047820 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047821 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047822 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047823 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047824 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047825 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047826 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047827 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047828 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047829 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047830 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047831 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047832 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01047833 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AC133425 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AC136584 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AC136645 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AF056704 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH473960 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | NM_017109 ⟹ NP_058805 | ||||||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||
| Position: |
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| Sequence: |
GCCAAATCGACTAGGTAAACAGAGTCCTGTGAAGCCCACTTCTGGTGGTGCAGAAGCCCCGGGAhide sequence |
Protein Sequences| Protein RefSeqs | NP_058805 | (Get FASTA) | NCBI Sequence Viewer |
| GenBank Protein | AAC24521 | (Get FASTA) | NCBI Sequence Viewer |
| EDM17123 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM17124 | (Get FASTA) | NCBI Sequence Viewer | |
| O70441 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_058805 ⟸ NM_017109 |
| - UniProtKB: | O70441 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MNFLRRRLSDSSFVANLPNGYMPDLQRPESSSSSPASPATERRHPQPLAASFSSPGSSLFSSFShide sequence |
TranscriptomeStrain Variation
Strain Sequence Variants (Rnor 6.0)
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Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:3799 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000026866 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000036740 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000037918 | ENTREZGENE, UniProtKB/TrEMBL |
| Gene3D-CATH | 3.30.1490.20 | UniProtKB/Swiss-Prot |
| InterPro | ATP_grasp_subdomain_1 | UniProtKB/Swiss-Prot |
| PreATP-grasp_dom_sf | UniProtKB/Swiss-Prot | |
| SYN2/3 | UniProtKB/Swiss-Prot | |
| Synapsin | UniProtKB/Swiss-Prot | |
| Synapsin_ATP-bd_dom | UniProtKB/Swiss-Prot | |
| Synapsin_CS | UniProtKB/Swiss-Prot | |
| Synapsin_P_site | UniProtKB/Swiss-Prot | |
| Synapsin_pre-ATP-grasp_dom | UniProtKB/Swiss-Prot | |
| KEGG Report | rno:29130 | UniProtKB/Swiss-Prot |
| NCBI Gene | 29130 | ENTREZGENE |
| PANTHER | PTHR10841:SF20 | UniProtKB/Swiss-Prot |
| Pfam | Synapsin | UniProtKB/Swiss-Prot |
| Synapsin_C | UniProtKB/Swiss-Prot | |
| Synapsin_N | UniProtKB/Swiss-Prot | |
| PhenoGen | Syn3 | PhenoGen |
| PRINTS | SYNAPSIN | UniProtKB/Swiss-Prot |
| PROSITE | SYNAPSIN_1 | UniProtKB/Swiss-Prot |
| SYNAPSIN_2 | UniProtKB/Swiss-Prot | |
| Superfamily-SCOP | SSF52440 | UniProtKB/Swiss-Prot |
| UniGene | Rn.162920 | ENTREZGENE |
| UniProt | A0A096MIT7_RAT | UniProtKB/TrEMBL |
| O70441 | ENTREZGENE, UniProtKB/Swiss-Prot |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2004-09-10 | Syn3 | synapsin III | synapsin 3 | Name updated | 1299863 | APPROVED | |
| 2002-06-10 | Syn3 | synapsin 3 | Name updated | 70585 | PROVISIONAL |
RGD Curation Notes| Note Type | Note | Reference |
|---|---|---|
| gene_function | binds ATP with high affinity and ADP with a lower affinity | 70029 |
| gene_regulation | ATP binding is inhibited by Ca2+ | 70029 |
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| More on Syn3 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 3799 |
| Created: | 2000-05-25 |
| Species: | Rattus norvegicus |
| Last Modified: | 2019-11-27 |
| Status: | ACTIVE |
