Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | DAPK3 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of DAPK3 mRNA | CTD | PMID:22079256 | 1,2-dimethylhydrazine | increases expression | ISO | Dapk3 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of DAPK3 mRNA | CTD | PMID:22206623 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | Dapk3 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DAPK3 mRNA | CTD | PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of DAPK3 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Dapk3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of DAPK3 mRNA | CTD | PMID:21570461 and PMID:24680724 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Dapk3 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of DAPK3 mRNA | CTD | PMID:20188158 | 3H-1,2-dithiole-3-thione | decreases expression | EXP | | 6480464 | 1 and 2-dithiol-3-thione results in decreased expression of DAPK3 mRNA | CTD | PMID:19162173 | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of DAPK3 mRNA | CTD | PMID:36041667 | 5-aza-2'-deoxycytidine | increases expression | ISO | DAPK3 (Homo sapiens) | 6480464 | Decitabine results in increased expression of DAPK3 mRNA | CTD | PMID:19037991 | 6-propyl-2-thiouracil | increases methylation | EXP | | 6480464 | Propylthiouracil results in increased methylation of DAPK3 promoter | CTD | PMID:33150595 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of DAPK3 mRNA | CTD | PMID:33150595 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of DAPK3 mRNA | CTD | PMID:28959563 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of DAPK3 mRNA | CTD | PMID:16483693 | antirheumatic drug | increases expression | ISO | DAPK3 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of DAPK3 mRNA | CTD | PMID:24449571 | Aroclor 1254 | increases expression | ISO | DAPK3 (Homo sapiens) | 6480464 | Chlorodiphenyl (54% Chlorine) results in increased expression of DAPK3 mRNA | CTD | PMID:16934159 | atrazine | decreases expression | EXP | | 6480464 | Atrazine results in decreased expression of DAPK3 mRNA | CTD | PMID:36841081 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of DAPK3 mRNA | CTD | PMID:21839799 | benzo[a]pyrene | decreases methylation | ISO | DAPK3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of DAPK3 exon | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of DAPK3 protein | CTD | PMID:21467743 | bexarotene | decreases expression | EXP | | 6480464 | bexarotene results in decreased expression of DAPK3 mRNA | CTD | PMID:16648578 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of DAPK3 mRNA | CTD | PMID:25181051 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of DAPK3 mRNA | CTD | PMID:36041667 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of DAPK3 mRNA | CTD | PMID:33296240 and PMID:34947998 | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of DAPK3 mRNA | CTD | PMID:36041667 | butan-1-ol | multiple interactions | ISO | DAPK3 (Homo sapiens) | 6480464 | [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of DAPK3 mRNA | CTD | PMID:29432896 | butanal | increases expression | ISO | DAPK3 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of DAPK3 mRNA | CTD | PMID:26079696 | cadmium atom | multiple interactions | ISO | DAPK3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of DAPK3 mRNA | CTD | PMID:35301059 | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of DAPK3 promoter | CTD | PMID:22457795 | cadmium dichloride | multiple interactions | ISO | DAPK3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of DAPK3 mRNA | CTD | PMID:35301059 | caffeine | decreases phosphorylation | ISO | DAPK3 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of DAPK3 protein | CTD | PMID:35688186 | cannabidiol | affects methylation | EXP | | 6480464 | Cannabidiol affects the methylation of DAPK3 gene | CTD | PMID:30521419 | carbon nanotube | increases expression | ISO | Dapk3 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | chlorpyrifos | increases expression | ISO | Dapk3 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of DAPK3 mRNA | CTD | PMID:32715474 and PMID:37019170 | choline | multiple interactions | ISO | Dapk3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DAPK3 gene | CTD | PMID:20938992 | chromium atom | increases expression | EXP | | 6480464 | Chromium results in increased expression of DAPK3 mRNA | CTD | PMID:17692352 | cisplatin | increases response to substance | ISO | DAPK3 (Homo sapiens) | 6480464 | DAPK3 results in increased susceptibility to Cisplatin | CTD | PMID:21775533 | cisplatin | decreases expression | ISO | DAPK3 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of DAPK3 mRNA | CTD | PMID:27392435 | cobalt dichloride | increases expression | ISO | DAPK3 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of DAPK3 mRNA | CTD | PMID:19376846 | copper(II) sulfate | increases expression | ISO | DAPK3 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of DAPK3 mRNA | CTD | PMID:19549813 | coumarin | decreases phosphorylation | ISO | DAPK3 (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of DAPK3 protein | CTD | PMID:35688186 | cyclosporin A | increases expression | ISO | DAPK3 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of DAPK3 mRNA | CTD | PMID:20106945 and PMID:25562108 | diazinon | affects expression | EXP | | 6480464 | Diazinon affects the expression of DAPK3 mRNA | CTD | PMID:22546817 | dioxygen | multiple interactions | ISO | Dapk3 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of DAPK3 mRNA | CTD | PMID:30529165 | elemental selenium | multiple interactions | ISO | DAPK3 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of DAPK3 mRNA | CTD | PMID:19244175 | elemental selenium | increases expression | ISO | DAPK3 (Homo sapiens) | 6480464 | Selenium results in increased expression of DAPK3 mRNA | CTD | PMID:19244175 | ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of DAPK3 mRNA | CTD | PMID:15353170 | ethanol | multiple interactions | ISO | DAPK3 (Homo sapiens) | 6480464 | [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of DAPK3 mRNA | CTD | PMID:29432896 | fenthion | increases expression | ISO | Dapk3 (Mus musculus) | 6480464 | Fenthion results in increased expression of DAPK3 mRNA | CTD | PMID:34813904 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of DAPK3 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | Dapk3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DAPK3 gene | CTD | PMID:20938992 | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of DAPK3 gene | CTD | PMID:22079235 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of DAPK3 mRNA | CTD | PMID:22061828 and PMID:33387578 | glycidol | decreases expression | EXP | | 6480464 | glycidol results in decreased expression of DAPK3 mRNA | CTD | PMID:33150645 | glycidol | increases methylation | EXP | | 6480464 | glycidol results in increased methylation of DAPK3 promoter | CTD | PMID:33150595 | hydrogen cyanide | decreases expression | ISO | Dapk3 (Mus musculus) | 6480464 | Hydrogen Cyanide results in decreased expression of DAPK3 mRNA | CTD | PMID:33914522 | isobutanol | multiple interactions | ISO | DAPK3 (Homo sapiens) | 6480464 | [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of DAPK3 mRNA | CTD | PMID:29432896 | L-methionine | multiple interactions | ISO | Dapk3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DAPK3 gene | CTD | PMID:20938992 | leflunomide | increases expression | ISO | DAPK3 (Homo sapiens) | 6480464 | leflunomide results in increased expression of DAPK3 mRNA | CTD | PMID:28988120 | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of DAPK3 mRNA | CTD | PMID:30467583 | methidathion | increases expression | ISO | Dapk3 (Mus musculus) | 6480464 | methidathion results in increased expression of DAPK3 mRNA | CTD | PMID:34813904 | methotrexate | affects response to substance | ISO | DAPK3 (Homo sapiens) | 6480464 | DAPK3 protein affects the susceptibility to Methotrexate | CTD | PMID:16217747 | methoxyacetic acid | affects expression | EXP | | 6480464 | methoxyacetic acid affects the expression of DAPK3 mRNA | CTD | PMID:20864626 | methylphenidate | decreases expression | ISO | Dapk3 (Mus musculus) | 6480464 | Methylphenidate results in decreased expression of DAPK3 mRNA | CTD | PMID:22470460 | motexafin gadolinium | multiple interactions | ISO | DAPK3 (Homo sapiens) | 6480464 | motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of DAPK3 mRNA] | CTD | PMID:16357179 | motexafin gadolinium | decreases expression | ISO | DAPK3 (Homo sapiens) | 6480464 | motexafin gadolinium results in decreased expression of DAPK3 mRNA | CTD | PMID:16357179 | oxybenzone | increases expression | EXP | | 6480464 | oxybenzone results in increased expression of DAPK3 mRNA | CTD | PMID:30316929 | p-menthan-3-ol | decreases expression | ISO | DAPK3 (Homo sapiens) | 6480464 | Menthol results in decreased expression of DAPK3 mRNA | CTD | PMID:26760959 | paracetamol | affects expression | ISO | Dapk3 (Mus musculus) | 6480464 | Acetaminophen affects the expression of DAPK3 mRNA | CTD | PMID:17562736 | perfluorooctanoic acid | increases expression | ISO | DAPK3 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of DAPK3 protein | CTD | PMID:26879310 | phenobarbital | decreases expression | EXP | | 6480464 | Phenobarbital results in decreased expression of DAPK3 mRNA | CTD | PMID:19162173 | phenobarbital | affects expression | ISO | Dapk3 (Mus musculus) | 6480464 | Phenobarbital affects the expression of DAPK3 mRNA | CTD | PMID:23091169 | PhIP | increases expression | EXP | | 6480464 | 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased expression of DAPK3 mRNA | CTD | PMID:15215175 | pirinixic acid | multiple interactions | ISO | DAPK3 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of DAPK3 mRNA | CTD | PMID:19710929 | pirinixic acid | decreases expression | ISO | Dapk3 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of DAPK3 mRNA | CTD | PMID:18445702 | potassium chromate | multiple interactions | ISO | DAPK3 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of DAPK3 mRNA | CTD | PMID:22079256 | potassium chromate | decreases expression | ISO | DAPK3 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of DAPK3 mRNA | CTD | PMID:22079256 | potassium cyanide | increases expression | ISO | Dapk3 (Mus musculus) | 6480464 | Potassium Cyanide results in increased expression of DAPK3 mRNA | CTD | PMID:33914522 | pregnenolone 16alpha-carbonitrile | increases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in increased expression of DAPK3 mRNA | CTD | PMID:19162173 | quercetin | increases phosphorylation | ISO | DAPK3 (Homo sapiens) | 6480464 | Quercetin results in increased phosphorylation of DAPK3 protein | CTD | PMID:35688186 | selenium atom | multiple interactions | ISO | DAPK3 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of DAPK3 mRNA | CTD | PMID:19244175 | selenium atom | increases expression | ISO | DAPK3 (Homo sapiens) | 6480464 | Selenium results in increased expression of DAPK3 mRNA | CTD | PMID:19244175 | sodium fluoride | increases expression | ISO | Dapk3 (Mus musculus) | 6480464 | Sodium Fluoride results in increased expression of DAPK3 mRNA | CTD | PMID:27862939 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of DAPK3 mRNA | CTD | PMID:34492290 | Tributyltin oxide | decreases expression | EXP | | 6480464 | bis(tri-n-butyltin)oxide results in decreased expression of DAPK3 mRNA | CTD | PMID:17553608 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of DAPK3 mRNA | CTD | PMID:33387578 | trichostatin A | decreases expression | ISO | DAPK3 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of DAPK3 mRNA | CTD | PMID:24935251 | triptonide | affects expression | ISO | Dapk3 (Mus musculus) | 6480464 | triptonide affects the expression of DAPK3 mRNA | CTD | PMID:33045310 | urethane | increases expression | ISO | DAPK3 (Homo sapiens) | 6480464 | Urethane results in increased expression of DAPK3 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | Dapk3 (Mus musculus) | 6480464 | Valproic Acid affects the expression of DAPK3 mRNA | CTD | PMID:17292431 | valproic acid | increases methylation | EXP | | 6480464 | Valproic Acid results in increased methylation of DAPK3 promoter | CTD | PMID:33150595 | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of DAPK3 mRNA | CTD | PMID:33150595 | valproic acid | increases expression | ISO | DAPK3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of DAPK3 mRNA | CTD | PMID:23179753 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of DAPK3 mRNA | CTD | PMID:23034163 | vitamin E | increases expression | ISO | DAPK3 (Homo sapiens) | 6480464 | Vitamin E results in increased expression of DAPK3 mRNA | CTD | PMID:19244175 | vitamin E | multiple interactions | ISO | DAPK3 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of DAPK3 mRNA | CTD | PMID:19244175 | zinc acetate | multiple interactions | ISO | DAPK3 (Homo sapiens) | 6480464 | motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of DAPK3 mRNA] | CTD | PMID:16357179 | zinc acetate | increases expression | ISO | DAPK3 (Homo sapiens) | 6480464 | Zinc Acetate results in increased expression of DAPK3 mRNA | CTD | PMID:16357179 | |