Trhr (thyrotropin releasing hormone receptor)

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Gene: Trhr (thyrotropin releasing hormone receptor) Rattus norvegicus

Analyze

Symbol:

Trhr

Name:

thyrotropin releasing hormone receptor

RGD ID:

3904

Description:

Exhibits identical protein binding activity and thyrotropin-releasing hormone receptor activity. Involved in positive regulation of cytosolic calcium ion concentration and positive regulation of protein-containing complex assembly. Localizes to cell surface. Used to study hypertension. Human ortholog(s) of this gene implicated in congenital nongoitrous hypothyroidism 7 and hypertension. Orthologous to human TRHR (thyrotropin releasing hormone receptor); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH (+)-pilocarpine; 2,2',4,4',5,5'-hexachlorobiphenyl; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

thyroliberin receptor; thyrotropin-releasing hormone receptor; TRH-R

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Is Marker For:

Strains: SS.LEW-(D7Rat73-D7Rat128)/Ayd LEW.SS-(D7Rat73-D7Rat128)/Ayd

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	7	75,348,672 - 75,393,310 (+)	NCBI
Rnor_6.0 Ensembl	7	83,113,672 - 83,153,519 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	7	83,113,641 - 83,153,520 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	7	83,121,134 - 83,161,215 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	80,050,671 - 80,095,991 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	7	80,071,435 - 80,116,717 (+)	NCBI
Celera	7	72,334,405 - 72,378,742 (+)	NCBI		Celera
Cytogenetic Map	7	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

congenital hypothyroidism (ISS)

congenital nongoitrous hypothyroidism 7 (ISO)

hypertension (IDA)

hypothyroidism (ISO)

thyroid hormone resistance syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-pilocarpine (EXP)

2,2',4,4',5,5'-hexachlorobiphenyl (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

6-propyl-2-thiouracil (EXP)

adinazolam (EXP)

aflatoxin B1 (ISO)

alprazolam (EXP)

ammonium chloride (EXP)

anthra[1,9-cd]pyrazol-6(2H)-one (ISO)

benzo[a]pyrene (EXP,ISO)

carbonyl sulfide (EXP)

chlordiazepoxide (EXP)

corticosterone (EXP)

DDE (EXP)

decabromodiphenyl ether (EXP)

diazepam (EXP)

dibutyl phthalate (ISO)

estazolam (EXP)

fenvalerate (EXP)

flurazepam (EXP)

folic acid (ISO)

genistein (ISO)

kainic acid (EXP)

lead diacetate (EXP)

midazolam (EXP)

morphine (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (EXP)

picrotoxin (EXP)

potassium dichromate (ISO)

tetrachloromethane (EXP)

triazolam (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

G protein-coupled receptor signaling pathway (IEA)

phospholipase C-activating G protein-coupled receptor signaling pathway (IBA)

positive regulation of cytosolic calcium ion concentration (IDA)

positive regulation of protein-containing complex assembly (IDA)

Cellular Component

cell surface (IDA)

integral component of membrane (IEA)

plasma membrane (IEA)

Molecular Function

identical protein binding (IPI)

protein binding (ISO)

thyrotropin-releasing hormone receptor activity (IBA,IDA,IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

calcium/calcium-mediated signaling pathway (IEA)

References

References - curated


1.	de la Pena P, etal., Biochem J 1992 Jun 15;284 ( Pt 3):891-9.
2.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	GOA data from the GO Consortium
4.	Kimura N, etal., Endocrinology 1994 Jan;134(1):432-40.
5.	MGD data from the GO Consortium
6.	NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.	OMIM Disease Annotation Pipeline
8.	Pipeline to import KEGG annotations from KEGG into RGD
9.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10.	RGD automated import pipeline for gene-chemical interactions
11.	Satoh T, etal., Brain Res Mol Brain Res 1993 Dec;20(4):353-6.
12.	Sellar RE, etal., J Mol Endocrinol 1993 Apr;10(2):199-206.
13.	Suzuki S, etal., Circ Res. 1995 Oct;77(4):679-83.
14.	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
15.	Zhu CC, etal., J Biol Chem 2002 Aug 2;277(31):28228-37.

Additional References at PubMed

PMID:1317787	PMID:1334485	PMID:1338727	PMID:1373613	PMID:8889548	PMID:11278883	PMID:12393857	PMID:15879366	PMID:15905217	PMID:15944919	PMID:16257458	PMID:18795335
PMID:20691166

Genomics

Candidate Gene Status

Trhr is a candidate Gene for QTL Ept7

Comparative Map Data

Trhr
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	7	75,348,672 - 75,393,310 (+)	NCBI
Rnor_6.0 Ensembl	7	83,113,672 - 83,153,519 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	7	83,113,641 - 83,153,520 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	7	83,121,134 - 83,161,215 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	80,050,671 - 80,095,991 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	7	80,071,435 - 80,116,717 (+)	NCBI
Celera	7	72,334,405 - 72,378,742 (+)	NCBI		Celera
Cytogenetic Map	7	q31	NCBI

TRHR
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	8	109,086,585 - 109,121,565 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38.p13 Ensembl	8	109,086,621 - 109,119,584 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	8	109,086,585 - 109,121,565 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	8	110,098,814 - 110,133,794 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	110,168,900 - 110,200,989 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	8	110,168,901 - 110,200,989	NCBI
Celera	8	106,287,347 - 106,319,484 (+)	NCBI
Cytogenetic Map	8	q23.1	NCBI
HuRef	8	105,421,383 - 105,453,868 (+)	NCBI		HuRef
CHM1_1	8	110,139,931 - 110,172,069 (+)	NCBI		CHM1_1

Trhr
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	44,059,314 - 44,099,308 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	15	44,059,531 - 44,099,308 (+)	Ensembl
GRCm38	15	44,195,924 - 44,235,912 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	44,196,135 - 44,235,912 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	44,027,681 - 44,067,458 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	15	44,026,307 - 44,065,986 (+)	NCBI			mm8
Celera	15	44,658,539 - 44,700,386 (+)	NCBI		Celera
Cytogenetic Map	15	B3.2	NCBI
cM Map	15	16.82	NCBI

Trhr
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955417	16,529,293 - 16,565,359 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955417	16,529,293 - 16,565,359 (+)	NCBI	ChiLan1.0	ChiLan1.0

TRHR
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	8	107,886,593 - 107,918,825 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	107,886,593 - 107,918,825 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	8	105,739,651 - 105,780,470 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

TRHR
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	13	9,642,387 - 9,674,831 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	13	9,642,565 - 9,681,778 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Trhr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936470	35,808,569 - 35,844,062 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TRHR
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	28,436,758 - 28,482,893 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	28,480,637 - 28,482,031 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	30,819,213 - 31,155,972 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TRHR
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	103,798,423 - 103,835,284 (+)	NCBI
ChlSab1.1 Ensembl	8	103,800,175 - 103,831,628 (+)	Ensembl

Trhr
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624763	8,191,550 - 8,255,274 (+)	NCBI

Position Markers

RH144005

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	7	83,153,184 - 83,153,465	NCBI	Rnor6.0
Rnor_5.0	7	83,160,879 - 83,161,160	UniSTS	Rnor5.0
RGSC_v3.4	7	80,095,655 - 80,095,936	UniSTS	RGSC3.4
Celera	7	72,378,406 - 72,378,687	UniSTS
RH 3.4 Map	7	516.6	UniSTS
Cytogenetic Map	7	q31	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	2920071	124838025	Rat
1643004	Pain2	Pain QTL 2	1		mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	7	12328467	106995532	Rat
1300132	Bp182	Blood pressure QTL 182	3.49		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	25365633	93155402	Rat
1300127	Srn1	Serum renin concentration QTL 1	3.87		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	7	35867729	93155402	Rat
10755453	Coatc12	Coat color QTL 12		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	38547706	83547706	Rat
631534	Lnnr1	Liver neoplastic nodule remodeling QTL 1	3.85	0.001	liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)	7	40872682	85872682	Rat
7411605	Foco14	Food consumption QTL 14	24.1	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	40872682	85872682	Rat
631513	Scl7	Serum cholesterol level QTL 7	4.1		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	45301573	90301573	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	48118835	128611831	Rat
634326	Hc3	Hypercalciuria QTL 3	2.1		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	7	50252103	95252103	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	50704769	128085642	Rat
10053722	Scort27	Serum corticosterone level QTL 27	2.41	0.0083	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	7	50793818	95793818	Rat
1358361	Sradr5	Stress Responsive Adrenal Weight QTL 5	5.55		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	7	51251919	118477612	Rat
1300179	Kidm5	Kidney mass QTL 5	3.51		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	51251919	145729302	Rat
1300149	Cm6	Cardiac mass QTL 6	4.09		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	7	51252005	111589099	Rat
61428	Scl3	Serum cholesterol level QTL 3	3.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	53200344	98200344	Rat
738030	Anxrr8	Anxiety related response QTL 8	4.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	54259512	99259512	Rat
2316947	Rf58	Renal function QTL 58	7.8		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	7	55072862	123602998	Rat
2316952	Pur22	Proteinuria QTL 22	5.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	7	55072862	123602998	Rat
2316955	Stl24	Serum triglyceride level QTL 24	7.1		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	7	55072862	123602998	Rat
2300178	Bmd54	Bone mineral density QTL 54	5.3	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	7	55495689	100495689	Rat
2293644	Bmd29	Bone mineral density QTL 29	5.4	0.0001	femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	7	55495689	100495689	Rat
2293667	Bss42	Bone structure and strength QTL 42	7.25	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra cross-sectional area (CMO:0001689)	7	55495689	100495689	Rat
2293678	Bss24	Bone structure and strength QTL 24	6.71	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	7	55495689	100495689	Rat
2293685	Bmd21	Bone mineral density QTL 21	4.2	0.0003	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	7	55495689	100495689	Rat
2293696	Bmd32	Bone mineral density QTL 32	5.1	0.0001	femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	7	55495689	100495689	Rat
2293707	Bss32	Bone structure and strength QTL 32	7.64	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	7	55495689	100495689	Rat
1300151	Bp181	Blood pressure QTL 181	3.36		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	7	61047589	113228378	Rat
2317035	Aia16	Adjuvant induced arthritis QTL 16	2.71		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	7	68518460	113518460	Rat
1576303	Ept7	Estrogen-induced pituitary tumorigenesis QTL 7	3.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	7	69399586	111043530	Rat
1559283	Emca4	Estrogen-induced mammary cancer QTL 4	3.7		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	7	69399586	111043530	Rat
1298528	Bp169	Blood pressure QTL 169		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	70421228	115421228	Rat
70173	Niddm19	Non-insulin dependent diabetes mellitus QTL 19	4.33	0.00005	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	71448715	145729302	Rat
631540	Bw9	Body weight QTL 9	4.5		body mass (VT:0001259)	body weight (CMO:0000012)	7	77428105	127748511	Rat
1357338	Stl17	Serum triglyceride level QTL 17	3.23		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	77428234	122421148	Rat
634331	Pia17	Pristane induced arthritis QTL 17	4.7		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	7	81645773	140745067	Rat

Related Rat Strains

The following Strains have been annotated to Trhr

LEW.SS-(D7Rat73-D7Rat128)/Ayd

SS.LEW-(D7Rat73-D7Rat128)/Ayd

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	227
Count of miRNA genes:	144
Interacting mature miRNAs:	180
Transcripts:	ENSRNOT00000006783
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium
Low		6		6				46	10	4
Below cutoff	1	14	8	3	8	2	2	22	9	22	6	2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_013047	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AW522207	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000185	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M90308	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	S69160	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	S69161	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X64630	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X66726	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000006783 ⟹ ENSRNOP00000006783

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	7	83,113,672 - 83,153,519 (+)	Ensembl

RefSeq Acc Id:

NM_013047 ⟹ NP_037179

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	75,348,672 - 75,393,310 (+)	NCBI
Rnor_6.0	7	83,113,672 - 83,153,520 (+)	NCBI
Rnor_5.0	7	83,121,134 - 83,161,215 (+)	NCBI
RGSC_v3.4	7	80,050,671 - 80,095,991 (+)	RGD
Celera	7	72,334,405 - 72,378,742 (+)	RGD

Sequence:

show sequence

CTATGGTTTGACAGCCTCTGTGCTGCTCCTGCTGCTTCTGTTACTGCGGCTGTGTGGTCTGTCA
TGAGTTGAGACGGGATGTGAGGGTTTAGAGAAACTGCCGCTCTGAAGCCTGAGCCTCTGCTCAG
TGATCTTCCTGCCAGAGGGACTGGACAAGATTTCTTCTGCATGATTGGAAACTTGGACCTATTA
GCACGTCATCTACCCAGAGAAGCAGGCAGCGTGACAGAGTGAAGAGGGGAAGGAACTACTGCAG
AAACAAGCAAACAGCACAAAAGGTGGAGGCTGGAAAGATGTTTTAGAAAGTCTCTGTGTCAGAG
AAGCTTCAAGCCACTGAAGATGGAGAATGAAACCGTCAGTGAACTGAACCAAACCGAGCTCCCG
CCGCAAGTAGCCGTGGCCCTCGAGTACCAGGTGGTCACCATCTTACTTGTGGTGGTTATCTGTG
GACTGGGCATTGTGGGCAACATCATGGTAGTCCTGGTGGTCATGAGAACGAAGCACATGAGAAC
CGCTACAAACTGCTACCTGGTGAGTCTGGCTGTGGCGGATCTCATGGTCCTGGTGGCTGCAGGC
CTCCCCAACATCACCGACAGCATCTATGGTTCCTGGGTCTATGGCTATGTTGGCTGCCTCTGCA
TCACGTATCTCCAGTACTTAGGAATTAACGCATCTTCATGCTCAATAACAGCCTTTACCATTGA
GAGGTACATAGCAATCTGCCACCCCATCAAAGCCCAGTTTCTGTGCACATTTTCCAGAGCCAAA
AAAATCATTATCTTTGTCTGGGCCTTTACATCCATTTACTGTATGCTGTGGTTCTTCCTTCTGG
ATCTCAATATCAGCACCTACAAAGATGCTATTGTGATATCCTGTGGCTACAAGATCTCCCGCAA
CTACTACTCACCTATTTACCTAATGGACTTTGGCGTCTTTTATGTCATGCCAATGATCCTGGCC
ACTGTGCTTTACGGGTTTATAGCTAGAATCCTCTTCTTAAACCCCATTCCTTCAGACCCTAAAG
AAAACTCTAAGACGTGGAAAAATGACTCAACCCATCAGAACAAGAATATGAATTTAAACACCAC
CAACAGATGTTTCAACAGCACCGTTTCTTCCAGGAAGCAGGTCACCAAGATGCTTGCAGTGGTT
GTAATTCTGTTTGCCCTTTTATGGATGCCCTACAGGACTCTTGTGGTTGTCAACTCATTTCTCT
CCAGCCCTTTCCAGGAAAATTGGTTCTTGCTCTTTTGCAGAATTTGCATTTATCTCAACAGTGC
CATCAACCCGGTGATTTACAACCTCATGTCTCAGAAGTTTCGTGCAGCCTTCAGGAAGCTCTGC
AATTGCAAGCAGAAGCCCACTGAGAAAGCTGCTAACTACAGTGTGGCCCTAAATTACAGTGTCA
TCAAGGAGTCAGACCGCTTTAGCACAGAGCTAGATGACATCACCGTCACTGACACGTATGTGTC
AACCACAAAAGTATCATTTGATGACACCTGCTTGGCCTCCGAGAAGAATGGACCCAGTTCTTGT
ACATATGGATATTCTTTGACTGCCAAACAGGAGAAAATATGAACTTCCTCAAGAATACCTTGGG
CTGGTATTAATAAAGGAAATCTTTCAAAAAATTCAATGTGACTCAAAAAGATCCAACTGATCGA
AGGTCTTCATTCAGAAGTCAGTAAGAACATCGTGATACTTAAATGGTACAGGGTGGCACAATAA
GGAAGCAAACATCTAATCCCTAGCCATGAGGACAAGCCACTCCTGTTTTGATATATATATATAC
AAATTACTGGCATGCTTTTCCTTAATGTGTCTCTCTTTCTCAAAATAACTGTTATTTGCCAGAT
GACTCTGAACACATCCTGGAAACCAATTTGTTCTGAGCCTCCACATATGTCCTTCAATACCCTT
GAATACCAAATAATTCTGAATAGGCAAGTTAAACAGAAAATCCCATGGAGGACAAGTTCATTTC
ATGTTTGTCTCCAAGAAATTGAACTAAGATGCTGAGCTCAACATTGACTTTCTCTTGAATGAAT
GAACGAACGAACGAAAGAATGAATGAACATGAATAAGTAAATTTATGAATCTCCAACTAAGAAA
TATAACGTAAAATCTTCATGATGCCTGATTTCCTCATAGATTTGTTCACAAATATAAAACTTGT
TTGCCTTTTGTTTTTATCATCTTAAACCATTCTCTTGGCTTATTAAAATGTACTATATTTTGTC
AGATCATGGTCACCACCATCTCTGTGTATATATTATGAATACAAAGTTCAATAGTACTCTCAAA
TCTCTCACCTAATTTAATAATGATCAAGATTATTACATGTATGTTCAGAGAATAACAACATACT
ATCACTGACATGTGAATAAAATTAAATGTGCAGAGTACATGGTAGGAAGAGAAGTTATATGATT
TCAGATTACAAACCTTAGAATTCCTCATTGGGAAAAGAATATCAGGGGGGTGCTAGAGTAATTA
GAACAACCTCATAGGAAAGCTTGAATTTCTTATAAGAATAGACTTGGCTTAGATAGGAAAAGAC
AAGTGATGTAAGGAAAGAGAGGTGAGTAAGGGTAGGAGGAAAAGAAACAAACTCTAGGTGTAAT
GGATAATGTGTCCAGTTAAGTGTGACTCATTGGGGATTGATCAAGGCAAGCAACTAGAAGAAAG
GAAAGAAGGGAAATAAAGTATTTCCTGATTATTGTATTTGTTGAGGAAATAGTCAGCCAGACAG
GTGGTAGATGTGTATATTAGTAAGCTGTCATGTATTTTCTAAACATTGTAAATTTCACTTATTA
TCTATAAAAATGTAGTATGCTATTTGTCTCCTAAGTGTTATAATTCTGTAAGTATCCTAAAGTC
ATAATTTCCAGGTAAAAACTAATTGTATATGTGTATATCTTTTCTATATTGCACTGTTATCATA
TATGGGATATATTTATTTATGTATATATGATTCAGAGGTCCTTAACAGCCATGAAGTTATCCAG
TTATGCTCACCGTAGAGATCCAAGCTAGCTCATAGGCCCTTCATATGCCTAAGCATCCATATTA
AATGAGAAACTGATAAGCAGTGACAAGCTTCTAATGCCCTCACCCTGTTGACTTGCATGCTGCT
TATATCGTGCTCCTGAATGCTTGGTTTCTTACAACATGCCTCTGAATGTTTTGGTTTCCTTTTA
CCATTTGTAGAGAGCTGTATACTCACTCATCTCATTGCTTGGAGATCAATCATTGTGTCCGTGT
GGAAAAATAATCTCCTTTAAGAAAGTGCAGTATTATGTGTTCTCTCTGCAATGGGAAACTATTA
CTGTATGTGTATGCATGCACAATAAAGTATCAAACTGAAAGATCCAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006241611 ⟹ XP_006241673

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	83,113,641 - 83,153,520 (+)	NCBI
Rnor_5.0	7	83,121,134 - 83,161,215 (+)	NCBI

Sequence:

show sequence

GAGAGAGAGCGCACTCTCATTAAGGGAGGATCTATGGTTTGACAGCCTCTGTGCTGCTCCTGCT
GCTTCTGTTACTGCGGCTGTGTGGTCTGTCATGAGTTGAGACGGGATGTGAGGGTTTAGAGAAA
CTGCCGCTCTGAAGCCTGAGCCTCTGCTCAGTGATCTTCCTGCCAGAGGGACTGGACAAGATTT
CTTCTGCATGATTGGAAACTTGGACCTATTAGCACGTCATCTACCCAGAGAAGCAGGCAGCGTG
ACAGAGTGAAGAGGGGAAGGAACTACTGCAGAAACAAGCAAACAGCACAAAAGGTGGAGGCTGG
AAAGATGTTTTAGAAAGTCTCTGTGTCAGAGAAGCTTCAAGCCACTGAAGATGGAGAATGAAAC
CGTCAGTGAACTGAACCAAACCGAGCTCCCGCCGCAAGTAGCCGTGGCCCTCGAGTACCAGGTG
GTCACCATCTTACTTGTGGTGGTTATCTGTGGACTGGGCATTGTGGGCAACATCATGGTAGTCC
TGGTGGTCATGAGAACGAAGCACATGAGAACCCCTACAAACTGCTACCTGGTGAGTCTGGCTGT
GGCGGATCTCATGGTCCTGGTGGCTGCAGGCCTCCCCAACATCACCGACAGCATCTATGGTTCC
TGGGTCTATGGCTATGTTGGCTGCCTCTGCATCACGTATCTCCAGTACTTAGGAATTAACGCAT
CTTCATGCTCAATAACAGCCTTTACCATTGAGAGGTACATAGCAATCTGCCACCCCATCAAAGC
CCAGTTTCTGTGCACATTTTCCAGAGCCAAAAAAATCATAATCTTTGTCTGGGCCTTTACATCC
ATTTACTGTATGCTGTGGTTCTTCCTTCTGGATCTCAATATCAGCACCTACAAAGATGCTATTG
TGATATCCTGTGGCTACAAGATCTCCCGCAACTACTACTCACCTATTTACCTAATGGACTTTGG
CGTCTTTTATGTCATGCCAATGATCCTGGCCACTGTGCTTTACGGGTTTATAGCTAGAATCCTC
TTCTTAAACCCCATTCCTTCAGACCCTAAAGAAAACTCTAAGACGTGGAAAAATGACTCAACCC
ATCAGAACAAGAATATGAATTTAAACACCACCAACAGATGTTTCAACAGCACCGTTTCTTCCAG
GAAGCAGGTCACCAAGATGCTTGCAGTGGTTGTAATTCTGTTTGCCCTTTTATGGATGCCCTAC
AGGACTCTTGTGGTTGTCAACTCATTTCTCTCCAGCCCTTTCCAGGAAAATTGGTTCTTGCTCT
TTTGCAGAATTTGCATTTATCTCAACAGTGCCATCAACCCGGTGATTTACAACCTCATGTCTCA
GAAGTTTCGTGCAGCCTTCAGGAAGCTCTGCAATTGCAAGCAGAAGCCCACTGAGAAAGCTGCT
AACTACAGTGTGGCCCTAAATTACAGTGTCATCAAGGAGTCAGACCGCTTTAGCACAGAGCTAG
ATGACATCACCGTCACTGACACGTATGTGTCAACCACAAAAGTATCATTTGATGACACCTGCTT
GGCCTCCGAGAATGGACCCAGTTCTTGTACATATGGATATTCTTTGACTGCCAAACAGGAGAAA
ATATGAACTTCCTCAAGAATACCTTGGGCTGGTATTAATAAAGGAAATCTTTCAAAAAATTCAA
TGTGACTCAAAAAGATCCAACTGATCGAAGGTCTTCATTCAGAAGTCAGTAAGAACATCGTGAT
ACTTAAATGGTACAGGGTGGCACAATAAGGAAGCAAACATCTAATCCCTAGCCATGAGGACAAG
CCACTCCTGTTTTGATATATATATATACAAATTACTGGCATGCTTTTCCTTAATGTGTCTCTCT
TTCTCAAAATAACTGTTATTTGCCAGATGACTCTGAACACATCCTGGAAACCAATTTGTTCTGA
GCCTCCACATATGTCCTTCAATACCCTTGAATACCAAATAATTCTGAATAGGCAAGTTAAACAG
AAAATCCCATGGAGGACAAGTTCATTTCATGTTTGTATCCAAGAAATTGAACTAAGATGCTGAG
CTCAACATTGACTTTCTCTTGAATGAATGAACGAACGAACGAAAGAATGAATGAACATGAATAA
GTAAATTTATGAATCTCCAACTAAGAAATATAACGTAAAATCTTCATGATGCCTGATTTCCTCA
TAGATTTGTTTACAAATATAAAACTTGTTTGCCTTTTGTTTTTATCATCTTAAACCATTCTCTT
GGCTTATTAAAATGTACTATATTTTGTCAGATCATGGTCACCACCATCTCTGTGTATATATTAT
GAATACAAAGTTCAATAGTACTCTCAAATCTCTCACCTAATTTAATAATGATCAAGATTATTAC
ATGTATGTTCAGAGAATAACAACATACTATCACTGACATGTGAATAAAATTAAATGTGCAGAGT
ACATGGTAGGAAGAGAAGTTATATGATTTCAGATTACAAACCTTAGAATTCCTCATTGGGAAAA
GAATATCAGGGGGGTGCTAGAGTAATTAGAACAACCTCATAGGAAAGCTTGAATTTCTTATAAG
AATAGACTTGGCTTAGATAGGAAAAGACAAGTGATGTAAGGAAAGAGAGGTGAGTAAGGGTAGG
AGGAAAAGAAACAAACTCTAGGTGTAATGGATAATGTGTCCAGTTAAGTGTGACTCATTGGGGA
TTGATCAAGGCAAGCAACTAGAAGAAAGGAAAGAAGGGAAATAAAGTATTTCCTGATTATTGTA
TTTGTTGAGGAAATAGTCAGCCAGACAGGTGGTAGATGTGTATATTAGTAAGCTGTCATGTATT
TTCTAAACATTGTAAATTTCACTTATTATCTATAAAAATGTAGTATGCTATTTGTCTCCTAAGT
GTTATAATTCTGTAAGTATCCTAAAGTCATAATTTCCAGGTAAAAACTAATTGTATATGTGTAT
ATCTTTTCTATATTGCACTGTTATCATATATGGGATATATTTATTTATGTATATATGATTCAGA
GGTCCTTAACAGCCATGAAGTTATCCAGTTATGCTCACCGTAGAGATCCAAGCTAGCTCATAGG
CCCTTCATATGCCTAAGCATCCATATTAAATGAGAAACTGATAAGCAGTGACAAGCTTCTAATG
CCCTCACCCTGTTGACTTGCATGCTGCTTATATCGTGCTCCTGAATGCTTGGTTTCTTACAACA
TGCCTCTGAATGTTTTGGTTTCCTTTTACCATTTGTAGAGAGCTGTATACTCACTCATCTCATT
GCTTGGAGATCAATCATTGTGTCCGTGTGGAAAAATAATCTCCTTTAAGAAAGTGCAGTATTAT
GTGTTCTCTCTGCAATGGGAAACTATTACTGTATGTGTATGCATGCACAATAAAGTATCAAACT
GAAAGATCCA

hide sequence

RefSeq Acc Id:

XM_017594675 ⟹ XP_017450164

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	83,113,641 - 83,153,520 (+)	NCBI

Sequence:

show sequence

GAGAGAGAGCGCACTCTCATTAAGGGAGGATCTATGGTTTGACAGCCTCTGTGCTGCTCCTGCT
GCTTCTGTTACTGCGGCTGTGTGGTCTGTCATGAGTTGAGACGGGATGTGAGGGTTTAGAGAAA
CTGCCGCTCTGAAGCCTGAGCCTCTGCTCAGTGATCTTCCTGCCAGAGGGACTGGACAAGATTT
CTTCTGCATGATTGGAAACTTGGACCTATTAGCACGTCATCTACCCAGAGAAGCAGGCAGCGTG
ACAGAGTGAAGAGGGGAAGGAACTACTGCAGAAACAAGCAAACAGCACAAAAGGTGGAGGCTGG
AAAGATGTTTTAGAAAGTCTCTGTGTCAGAGAAGCTTCAAGCCACTGAAGATGGAGAATGAAAC
CGTCAGTGAACTGAACCAAACCGAGCTCCCGCCGCAAGTAGCCGTGGCCCTCGAGTACCAGGTG
GTCACCATCTTACTTGTGGTGGTTATCTGTGGACTGGGCATTGTGGGCAACATCATGGTAGTCC
TGGTGGTCATGAGAACGAAGCACATGAGAACCCCTACAAACTGCTACCTGGTGAGTCTGGCTGT
GGCGGATCTCATGGTCCTGGTGGCTGCAGGCCTCCCCAACATCACCGACAGCATCTATGGTTCC
TGGGTCTATGGCTATGTTGGCTGCCTCTGCATCACGTATCTCCAGTACTTAGGAATTAACGCAT
CTTCATGCTCAATAACAGCCTTTACCATTGAGAGGTACATAGCAATCTGCCACCCCATCAAAGC
CCAGTTTCTGTGCACATTTTCCAGAGCCAAAAAAATCATAATCTTTGTCTGGGCCTTTACATCC
ATTTACTGTATGCTGTGGTTCTTCCTTCTGGATCTCAATATCAGCACCTACAAAGATGCTATTG
TGATATCCTGTGGCTACAAGATCTCCCGCAACTACTACTCACCTATTTACCTAATGGACTTTGG
CGTCTTTTATGTCATGCCAATGATCCTGGCCACTGTGCTTTACGGGTTTATAGCTAGAATCCTC
TTCTTAAACCCCATTCCTTCAGACCCTAAAGAAAACTCTAAGACGTGGAAAAATGACTCAACCC
ATCAGAACAAGAATATGAATTTAAACACCACCAACAGATGTTTCAACAGCACCGTTTCTTCCAG
GAAGCAGGTCACCAAGATGCTTGCAGTGGTTGTAATTCTGTTTGCCCTTTTATGGATGCCCTAC
AGGACTCTTGTGGTTGTCAACTCATTTCTCTCCAGCCCTTTCCAGGAAAATTGGTTCTTGCTCT
TTTGCAGAATTTGCATTTATCTCAACAGTGCCATCAACCCGGTGATTTACAACCTCATGTCTCA
GAAGTTTCGTGCAGCCTTCAGGAAGCTCTGCAATTGCAAGCAGAAGCCCACTGAGAAAGCTGCT
AACTACAGTGTGGCCCTAAATTACAGTGTCATCAAGGAGTCAGACCGCTTTAGCACAGAGCTAG
ATGACATCACCGTCACTGACACGTTGAACTTTGACCTAGTGTCCCAGTTATTATTAGACAGAAT
GGACCCAGTTCTTGTACATATGGATATTCTTTGACTGCCAAACAGGAGAAAATATGAACTTCCT
CAAGAATACCTTGGGCTGGTATTAATAAAGGAAATCTTTCAAAAAATTCAATGTGACTCAAAAA
GATCCAACTGATCGAAGGTCTTCATTCAGAAGTCAGTAAGAACATCGTGATACTTAAATGGTAC
AGGGTGGCACAATAAGGAAGCAAACATCTAATCCCTAGCCATGAGGACAAGCCACTCCTGTTTT
GATATATATATATACAAATTACTGGCATGCTTTTCCTTAATGTGTCTCTCTTTCTCAAAATAAC
TGTTATTTGCCAGATGACTCTGAACACATCCTGGAAACCAATTTGTTCTGAGCCTCCACATATG
TCCTTCAATACCCTTGAATACCAAATAATTCTGAATAGGCAAGTTAAACAGAAAATCCCATGGA
GGACAAGTTCATTTCATGTTTGTATCCAAGAAATTGAACTAAGATGCTGAGCTCAACATTGACT
TTCTCTTGAATGAATGAACGAACGAACGAAAGAATGAATGAACATGAATAAGTAAATTTATGAA
TCTCCAACTAAGAAATATAACGTAAAATCTTCATGATGCCTGATTTCCTCATAGATTTGTTTAC
AAATATAAAACTTGTTTGCCTTTTGTTTTTATCATCTTAAACCATTCTCTTGGCTTATTAAAAT
GTACTATATTTTGTCAGATCATGGTCACCACCATCTCTGTGTATATATTATGAATACAAAGTTC
AATAGTACTCTCAAATCTCTCACCTAATTTAATAATGATCAAGATTATTACATGTATGTTCAGA
GAATAACAACATACTATCACTGACATGTGAATAAAATTAAATGTGCAGAGTACATGGTAGGAAG
AGAAGTTATATGATTTCAGATTACAAACCTTAGAATTCCTCATTGGGAAAAGAATATCAGGGGG
GTGCTAGAGTAATTAGAACAACCTCATAGGAAAGCTTGAATTTCTTATAAGAATAGACTTGGCT
TAGATAGGAAAAGACAAGTGATGTAAGGAAAGAGAGGTGAGTAAGGGTAGGAGGAAAAGAAACA
AACTCTAGGTGTAATGGATAATGTGTCCAGTTAAGTGTGACTCATTGGGGATTGATCAAGGCAA
GCAACTAGAAGAAAGGAAAGAAGGGAAATAAAGTATTTCCTGATTATTGTATTTGTTGAGGAAA
TAGTCAGCCAGACAGGTGGTAGATGTGTATATTAGTAAGCTGTCATGTATTTTCTAAACATTGT
AAATTTCACTTATTATCTATAAAAATGTAGTATGCTATTTGTCTCCTAAGTGTTATAATTCTGT
AAGTATCCTAAAGTCATAATTTCCAGGTAAAAACTAATTGTATATGTGTATATCTTTTCTATAT
TGCACTGTTATCATATATGGGATATATTTATTTATGTATATATGATTCAGAGGTCCTTAACAGC
CATGAAGTTATCCAGTTATGCTCACCGTAGAGATCCAAGCTAGCTCATAGGCCCTTCATATGCC
TAAGCATCCATATTAAATGAGAAACTGATAAGCAGTGACAAGCTTCTAATGCCCTCACCCTGTT
GACTTGCATGCTGCTTATATCGTGCTCCTGAATGCTTGGTTTCTTACAACATGCCTCTGAATGT
TTTGGTTTCCTTTTACCATTTGTAGAGAGCTGTATACTCACTCATCTCATTGCTTGGAGATCAA
TCATTGTGTCCGTGTGGAAAAATAATCTCCTTTAAGAAAGTGCAGTATTATGTGTTCTCTCTGC
AATGGGAAACTATTACTGTATGTGTATGCATGCACAATAAAGTATCAAACTGAAAGATCCA

hide sequence

RefSeq Acc Id:

XM_017594676 ⟹ XP_017450165

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	83,113,641 - 83,153,520 (+)	NCBI

Sequence:

show sequence

GAGAGAGAGCGCACTCTCATTAAGGGAGGATCTATGGTTTGACAGCCTCTGTGCTGCTCCTGCT
GCTTCTGTTACTGCGGCTGTGTGGTCTGTCATGAGTTGAGACGGGATGTGAGGGTTTAGAGAAA
CTGCCGCTCTGAAGCCTGAGCCTCTGCTCAGTGATCTTCCTGCCAGAGGGACTGGACAAGATTT
CTTCTGCATGATTGGAAACTTGGACCTATTAGCACGTCATCTACCCAGAGAAGCAGGCAGCGTG
ACAGAGTGAAGAGGGGAAGGAACTACTGCAGAAACAAGCAAACAGCACAAAAGGTGGAGGCTGG
AAAGATGTTTTAGAAAGTCTCTGTGTCAGAGAAGCTTCAAGCCACTGAAGATGGAGAATGAAAC
CGTCAGTGAACTGAACCAAACCGAGCTCCCGCCGCAAGTAGCCGTGGCCCTCGAGTACCAGGTG
GTCACCATCTTACTTGTGGTGGTTATCTGTGGACTGGGCATTGTGGGCAACATCATGGTAGTCC
TGGTGGTCATGAGAACGAAGCACATGAGAACCCCTACAAACTGCTACCTGGTGAGTCTGGCTGT
GGCGGATCTCATGGTCCTGGTGGCTGCAGGCCTCCCCAACATCACCGACAGCATCTATGGTTCC
TGGGTCTATGGCTATGTTGGCTGCCTCTGCATCACGTATCTCCAGTACTTAGGAATTAACGCAT
CTTCATGCTCAATAACAGCCTTTACCATTGAGAGGTACATAGCAATCTGCCACCCCATCAAAGC
CCAGTTTCTGTGCACATTTTCCAGAGCCAAAAAAATCATAATCTTTGTCTGGGCCTTTACATCC
ATTTACTGTATGCTGTGGTTCTTCCTTCTGGATCTCAATATCAGCACCTACAAAGATGCTATTG
TGATATCCTGTGGCTACAAGATCTCCCGCAACTACTACTCACCTATTTACCTAATGGACTTTGG
CGTCTTTTATGTCATGCCAATGATCCTGGCCACTGTGCTTTACGGGTTTATAGCTAGAATCCTC
TTCTTAAACCCCATTCCTTCAGACCCTAAAGAAAACTCTAAGACGTGGAAAAATGACTCAACCC
ATCAGAACAAGAATATGAATTTAAACACCACCAACAGATGTTTCAACAGCACCGTTTCTTCCAG
GAAGCAGGTCACCAAGATGCTTGCAGTGGTTGTAATTCTGTTTGCCCTTTTATGGATGCCCTAC
AGGACTCTTGTGGTTGTCAACTCATTTCTCTCCAGCCCTTTCCAGGAAAATTGGTTCTTGCTCT
TTTGCAGAATTTGCATTTATCTCAACAGTGCCATCAACCCGGTGATTTACAACCTCATGTCTCA
GAAGTTTCGTGCAGCCTTCAGGAAGCTCTGCAATTGCAAGCAGAAGCCCACTGAGAAAGCTGCT
AACTACAGTGTGGCCCTAAATTACAGTGTCATCAAGGAGTCAGACCGCTTTAGCACAGAGCTAG
ATGACATCACCGTCACTGACACAAGAATGGACCCAGTTCTTGTACATATGGATATTCTTTGACT
GCCAAACAGGAGAAAATATGAACTTCCTCAAGAATACCTTGGGCTGGTATTAATAAAGGAAATC
TTTCAAAAAATTCAATGTGACTCAAAAAGATCCAACTGATCGAAGGTCTTCATTCAGAAGTCAG
TAAGAACATCGTGATACTTAAATGGTACAGGGTGGCACAATAAGGAAGCAAACATCTAATCCCT
AGCCATGAGGACAAGCCACTCCTGTTTTGATATATATATATACAAATTACTGGCATGCTTTTCC
TTAATGTGTCTCTCTTTCTCAAAATAACTGTTATTTGCCAGATGACTCTGAACACATCCTGGAA
ACCAATTTGTTCTGAGCCTCCACATATGTCCTTCAATACCCTTGAATACCAAATAATTCTGAAT
AGGCAAGTTAAACAGAAAATCCCATGGAGGACAAGTTCATTTCATGTTTGTATCCAAGAAATTG
AACTAAGATGCTGAGCTCAACATTGACTTTCTCTTGAATGAATGAACGAACGAACGAAAGAATG
AATGAACATGAATAAGTAAATTTATGAATCTCCAACTAAGAAATATAACGTAAAATCTTCATGA
TGCCTGATTTCCTCATAGATTTGTTTACAAATATAAAACTTGTTTGCCTTTTGTTTTTATCATC
TTAAACCATTCTCTTGGCTTATTAAAATGTACTATATTTTGTCAGATCATGGTCACCACCATCT
CTGTGTATATATTATGAATACAAAGTTCAATAGTACTCTCAAATCTCTCACCTAATTTAATAAT
GATCAAGATTATTACATGTATGTTCAGAGAATAACAACATACTATCACTGACATGTGAATAAAA
TTAAATGTGCAGAGTACATGGTAGGAAGAGAAGTTATATGATTTCAGATTACAAACCTTAGAAT
TCCTCATTGGGAAAAGAATATCAGGGGGGTGCTAGAGTAATTAGAACAACCTCATAGGAAAGCT
TGAATTTCTTATAAGAATAGACTTGGCTTAGATAGGAAAAGACAAGTGATGTAAGGAAAGAGAG
GTGAGTAAGGGTAGGAGGAAAAGAAACAAACTCTAGGTGTAATGGATAATGTGTCCAGTTAAGT
GTGACTCATTGGGGATTGATCAAGGCAAGCAACTAGAAGAAAGGAAAGAAGGGAAATAAAGTAT
TTCCTGATTATTGTATTTGTTGAGGAAATAGTCAGCCAGACAGGTGGTAGATGTGTATATTAGT
AAGCTGTCATGTATTTTCTAAACATTGTAAATTTCACTTATTATCTATAAAAATGTAGTATGCT
ATTTGTCTCCTAAGTGTTATAATTCTGTAAGTATCCTAAAGTCATAATTTCCAGGTAAAAACTA
ATTGTATATGTGTATATCTTTTCTATATTGCACTGTTATCATATATGGGATATATTTATTTATG
TATATATGATTCAGAGGTCCTTAACAGCCATGAAGTTATCCAGTTATGCTCACCGTAGAGATCC
AAGCTAGCTCATAGGCCCTTCATATGCCTAAGCATCCATATTAAATGAGAAACTGATAAGCAGT
GACAAGCTTCTAATGCCCTCACCCTGTTGACTTGCATGCTGCTTATATCGTGCTCCTGAATGCT
TGGTTTCTTACAACATGCCTCTGAATGTTTTGGTTTCCTTTTACCATTTGTAGAGAGCTGTATA
CTCACTCATCTCATTGCTTGGAGATCAATCATTGTGTCCGTGTGGAAAAATAATCTCCTTTAAG
AAAGTGCAGTATTATGTGTTCTCTCTGCAATGGGAAACTATTACTGTATGTGTATGCATGCACA
ATAAAGTATCAAACTGAAAGATCCA

hide sequence

RefSeq Acc Id:

XM_017594677 ⟹ XP_017450166

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	83,113,641 - 83,153,520 (+)	NCBI

Sequence:

show sequence

GAGAGAGAGCGCACTCTCATTAAGGGAGGATCTATGGTTTGACAGCCTCTGTGCTGCTCCTGCT
GCTTCTGTTACTGCGGCTGTGTGGTCTGTCATGAGTTGAGACGGGATGTGAGGGTTTAGAGAAA
CTGCCGCTCTGAAGCCTGAGCCTCTGCTCAGTGATCTTCCTGCCAGAGGGACTGGACAAGATTT
CTTCTGCATGATTGGAAACTTGGACCTATTAGCACGTCATCTACCCAGAGAAGCAGGCAGCGTG
ACAGAGTGAAGAGGGGAAGGAACTACTGCAGAAACAAGCAAACAGCACAAAAGGTGGAGGCTGG
AAAGATGTTTTAGAAAGTCTCTGTGTCAGAGAAGCTTCAAGCCACTGAAGATGGAGAATGAAAC
CGTCAGTGAACTGAACCAAACCGAGCTCCCGCCGCAAGTAGCCGTGGCCCTCGAGTACCAGGTG
GTCACCATCTTACTTGTGGTGGTTATCTGTGGACTGGGCATTGTGGGCAACATCATGGTAGTCC
TGGTGGTCATGAGAACGAAGCACATGAGAACCCCTACAAACTGCTACCTGGTGAGTCTGGCTGT
GGCGGATCTCATGGTCCTGGTGGCTGCAGGCCTCCCCAACATCACCGACAGCATCTATGGTTCC
TGGGTCTATGGCTATGTTGGCTGCCTCTGCATCACGTATCTCCAGTACTTAGGAATTAACGCAT
CTTCATGCTCAATAACAGCCTTTACCATTGAGAGGTACATAGCAATCTGCCACCCCATCAAAGC
CCAGTTTCTGTGCACATTTTCCAGAGCCAAAAAAATCATAATCTTTGTCTGGGCCTTTACATCC
ATTTACTGTATGCTGTGGTTCTTCCTTCTGGATCTCAATATCAGCACCTACAAAGATGCTATTG
TGATATCCTGTGGCTACAAGATCTCCCGCAACTACTACTCACCTATTTACCTAATGGACTTTGG
CGTCTTTTATGTCATGCCAATGATCCTGGCCACTGTGCTTTACGGGTTTATAGCTAGAATCCTC
TTCTTAAACCCCATTCCTTCAGACCCTAAAGAAAACTCTAAGACGTGGAAAAATGACTCAACCC
ATCAGAACAAGAATATGAATTTAAACACCACCAACAGATGTTTCAACAGCACCGTTTCTTCCAG
GAAGCAGGTCACCAAGATGCTTGCAGTGGTTGTAATTCTGTTTGCCCTTTTATGGATGCCCTAC
AGGACTCTTGTGGTTGTCAACTCATTTCTCTCCAGCCCTTTCCAGGAAAATTGGTTCTTGCTCT
TTTGCAGAATTTGCATTTATCTCAACAGTGCCATCAACCCGGTGATTTACAACCTCATGTCTCA
GAAGTTTCGTGCAGCCTTCAGGAAGCTCTGCAATTGCAAGCAGAAGCCCACTGAGAAAGCTGCT
AACTACAGTGTGGCCCTAAATTACAGTGTCATCAAGGAGTCAGACCGCTTTAGCACAGAGCTAG
ATGACATCACCGTCACTGACACAATGGACCCAGTTCTTGTACATATGGATATTCTTTGACTGCC
AAACAGGAGAAAATATGAACTTCCTCAAGAATACCTTGGGCTGGTATTAATAAAGGAAATCTTT
CAAAAAATTCAATGTGACTCAAAAAGATCCAACTGATCGAAGGTCTTCATTCAGAAGTCAGTAA
GAACATCGTGATACTTAAATGGTACAGGGTGGCACAATAAGGAAGCAAACATCTAATCCCTAGC
CATGAGGACAAGCCACTCCTGTTTTGATATATATATATACAAATTACTGGCATGCTTTTCCTTA
ATGTGTCTCTCTTTCTCAAAATAACTGTTATTTGCCAGATGACTCTGAACACATCCTGGAAACC
AATTTGTTCTGAGCCTCCACATATGTCCTTCAATACCCTTGAATACCAAATAATTCTGAATAGG
CAAGTTAAACAGAAAATCCCATGGAGGACAAGTTCATTTCATGTTTGTATCCAAGAAATTGAAC
TAAGATGCTGAGCTCAACATTGACTTTCTCTTGAATGAATGAACGAACGAACGAAAGAATGAAT
GAACATGAATAAGTAAATTTATGAATCTCCAACTAAGAAATATAACGTAAAATCTTCATGATGC
CTGATTTCCTCATAGATTTGTTTACAAATATAAAACTTGTTTGCCTTTTGTTTTTATCATCTTA
AACCATTCTCTTGGCTTATTAAAATGTACTATATTTTGTCAGATCATGGTCACCACCATCTCTG
TGTATATATTATGAATACAAAGTTCAATAGTACTCTCAAATCTCTCACCTAATTTAATAATGAT
CAAGATTATTACATGTATGTTCAGAGAATAACAACATACTATCACTGACATGTGAATAAAATTA
AATGTGCAGAGTACATGGTAGGAAGAGAAGTTATATGATTTCAGATTACAAACCTTAGAATTCC
TCATTGGGAAAAGAATATCAGGGGGGTGCTAGAGTAATTAGAACAACCTCATAGGAAAGCTTGA
ATTTCTTATAAGAATAGACTTGGCTTAGATAGGAAAAGACAAGTGATGTAAGGAAAGAGAGGTG
AGTAAGGGTAGGAGGAAAAGAAACAAACTCTAGGTGTAATGGATAATGTGTCCAGTTAAGTGTG
ACTCATTGGGGATTGATCAAGGCAAGCAACTAGAAGAAAGGAAAGAAGGGAAATAAAGTATTTC
CTGATTATTGTATTTGTTGAGGAAATAGTCAGCCAGACAGGTGGTAGATGTGTATATTAGTAAG
CTGTCATGTATTTTCTAAACATTGTAAATTTCACTTATTATCTATAAAAATGTAGTATGCTATT
TGTCTCCTAAGTGTTATAATTCTGTAAGTATCCTAAAGTCATAATTTCCAGGTAAAAACTAATT
GTATATGTGTATATCTTTTCTATATTGCACTGTTATCATATATGGGATATATTTATTTATGTAT
ATATGATTCAGAGGTCCTTAACAGCCATGAAGTTATCCAGTTATGCTCACCGTAGAGATCCAAG
CTAGCTCATAGGCCCTTCATATGCCTAAGCATCCATATTAAATGAGAAACTGATAAGCAGTGAC
AAGCTTCTAATGCCCTCACCCTGTTGACTTGCATGCTGCTTATATCGTGCTCCTGAATGCTTGG
TTTCTTACAACATGCCTCTGAATGTTTTGGTTTCCTTTTACCATTTGTAGAGAGCTGTATACTC
ACTCATCTCATTGCTTGGAGATCAATCATTGTGTCCGTGTGGAAAAATAATCTCCTTTAAGAAA
GTGCAGTATTATGTGTTCTCTCTGCAATGGGAAACTATTACTGTATGTGTATGCATGCACAATA
AAGTATCAAACTGAAAGATCCA

hide sequence

Protein Sequences


Protein RefSeqs	NP_037179	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA42277	(Get FASTA)	NCBI Sequence Viewer
	AAB29945	(Get FASTA)	NCBI Sequence Viewer
	AAB29946	(Get FASTA)	NCBI Sequence Viewer
	CAA45913	(Get FASTA)	NCBI Sequence Viewer
	CAA47263	(Get FASTA)	NCBI Sequence Viewer
	EDM16314	(Get FASTA)	NCBI Sequence Viewer
	EDM16315	(Get FASTA)	NCBI Sequence Viewer
	Q01717	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_037179 ⟸ NM_013047

- UniProtKB:

Q01717 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MENETVSELNQTELPPQVAVALEYQVVTILLVVVICGLGIVGNIMVVLVVMRTKHMRTATNCYL
VSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAIC
HPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPIY
LMDFGVFYVMPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNKNMNLNTTNRCFNS
TVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIY
NLMSQKFRAAFRKLCNCKQKPTEKAANYSVALNYSVIKESDRFSTELDDITVTDTYVSTTKVSF
DDTCLASEKNGPSSCTYGYSLTAKQEKI

hide sequence

RefSeq Acc Id:

XP_006241673 ⟸ XM_006241611

- Peptide Label:

isoform X1

- Sequence:

show sequence

MENETVSELNQTELPPQVAVALEYQVVTILLVVVICGLGIVGNIMVVLVVMRTKHMRTPTNCYL
VSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAIC
HPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPIY
LMDFGVFYVMPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNKNMNLNTTNRCFNS
TVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIY
NLMSQKFRAAFRKLCNCKQKPTEKAANYSVALNYSVIKESDRFSTELDDITVTDTYVSTTKVSF
DDTCLASENGPSSCTYGYSLTAKQEKI

hide sequence

RefSeq Acc Id:

XP_017450164 ⟸ XM_017594675

- Peptide Label:

isoform X2

- Sequence:

show sequence

MENETVSELNQTELPPQVAVALEYQVVTILLVVVICGLGIVGNIMVVLVVMRTKHMRTPTNCYL
VSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAIC
HPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPIY
LMDFGVFYVMPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNKNMNLNTTNRCFNS
TVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIY
NLMSQKFRAAFRKLCNCKQKPTEKAANYSVALNYSVIKESDRFSTELDDITVTDTLNFDLVSQL
LLDRMDPVLVHMDIL

hide sequence

RefSeq Acc Id:

XP_017450165 ⟸ XM_017594676

- Peptide Label:

isoform X3

- Sequence:

show sequence

MENETVSELNQTELPPQVAVALEYQVVTILLVVVICGLGIVGNIMVVLVVMRTKHMRTPTNCYL
VSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAIC
HPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPIY
LMDFGVFYVMPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNKNMNLNTTNRCFNS
TVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIY
NLMSQKFRAAFRKLCNCKQKPTEKAANYSVALNYSVIKESDRFSTELDDITVTDTRMDPVLVHM
DIL

hide sequence

RefSeq Acc Id:

XP_017450166 ⟸ XM_017594677

- Peptide Label:

isoform X4

- Sequence:

show sequence

MENETVSELNQTELPPQVAVALEYQVVTILLVVVICGLGIVGNIMVVLVVMRTKHMRTPTNCYL
VSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAIC
HPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPIY
LMDFGVFYVMPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNKNMNLNTTNRCFNS
TVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIY
NLMSQKFRAAFRKLCNCKQKPTEKAANYSVALNYSVIKESDRFSTELDDITVTDTMDPVLVHMD
IL

hide sequence

RefSeq Acc Id:

ENSRNOP00000006783 ⟸ ENSRNOT00000006783

Protein Domains

G_PROTEIN_RECEP_F1_2

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Damaging Variants

Assembly: Rnor_5.0

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
7	83122275	83122276	C	G	snv	GH/OmrMcwi (MCW), ZFDM (KyushuU), FHL/EurMcwi (MCW), SBN/Ygl (MCW), SS/JrHsdMcwi (MCW), LH/MavRrrc (KNAW), LL/MavRrrc (KNAW), LN/MavRrrc (KNAW), MHS/Gib (KNAW), MR/N (KNAW), SS/Jr (KNAW), SS/JrHsdMcwi (KNAW), WAG/Rij (KNAW), BBDP/WorN (KNAW), SBN/Ygl (KNAW), FHH/EurMcwi (KNAW), FHL/EurMcwi (KNAW), LEW/Crl (KNAW), LEW/NCrl (KNAW), SDLEF7/Barth (UDEL), Crl:SD (UDEL), BUF/MNa (KyushuU), HTX/Kyo (KyushuU), RCS/Kyo (KyushuU), ZF (KyushuU), FHH/EurMcwi (MCW)

Assembly: Rnor_6.0

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
7	83114782	83114783	C	G	snv	GH/OmrMcwi (MCW), WAG/Rij (RGD), FHL/EurMcwi (MCW), SBN/Ygl (MCW), SS/JrHsdMcwi (MCW), CDR, CDS, MR/N (MCW), FHL/EurMcwi (RGD), BBDP/Wor (RGD), FHH/EurMcwi (RGD), LEW/Crl (RGD), LEW/NCrlBR (RGD), LH/MavRrrc (RGD), LN/MavRrrc (RGD), LL/MavRrrc (RGD), MHS/Gib (RGD), SBN/Ygl (RGD), SS/Jr (RGD), SS/JrHsdMcwi (RGD), FHH/EurMcwi (MCW)

Assembly: RGSC_v3.4

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
7	80051781	80051782	C	G	snv	FHH/EurMcwi (MDC), WAG/Rij (ICL), MR/N (KNAW), FHH/EurMcwi (MCW), FHL/EurMcwi (MCW), SS/JrHsdMcwi (MCW), GH/OmrMcwi (MCW), BBDP/WorN (ICL), FHH/EurMcwi (ICL), FHL/EurMcwi (ICL), LEW/Crl (ICL), LEW/NCrl (ICL), LH/MavRrrc (ICL), LL/MavRrrc (ICL), LN/MavRrrc (ICL), MHS/Gib (ICL), SBN/Ygl (ICL), SS/Jr (ICL), SS/JrHsdMcwi (ICL), SS/JrHsdMcwi (MDC)

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:3904	AgrOrtholog
Ensembl Genes	ENSRNOG00000005048	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000006783	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000006783	ENTREZGENE, UniProtKB/TrEMBL
InterPro	GPCR_Rhodpsn	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TRH_rcpt_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:25570	UniProtKB/Swiss-Prot
NCBI Gene	25570	ENTREZGENE
PANTHER	PTHR46061	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	7tm_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Trhr	PhenoGen
PRINTS	GPCRRHODOPSN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	THYROLIBRINR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TRHRFAMILY	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	7TM_GPCR_Srsx	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR	TC218150
UniProt	G3V6M9_RAT	UniProtKB/TrEMBL
	Q01717	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q63948	UniProtKB/Swiss-Prot
	Q63949	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2002-06-10	Trhr	Thyrotropin releasing hormone receptor			Symbol and Name status set to approved	70586	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_protein	forms monomers and dimers	730055
gene_regulation	receptor dimerization and phosphorylation increases in the presence of thyrotropin-releasing hormone	730055

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)