Trhr (thyrotropin releasing hormone receptor) - Rat Genome Database

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Gene: Trhr (thyrotropin releasing hormone receptor) Rattus norvegicus
Analyze
Symbol: Trhr
Name: thyrotropin releasing hormone receptor
RGD ID: 3904
Description: Enables identical protein binding activity and thyrotropin-releasing hormone receptor activity. Involved in positive regulation of cytosolic calcium ion concentration and positive regulation of protein-containing complex assembly. Located in cell surface. Used to study hypertension. Human ortholog(s) of this gene implicated in congenital nongoitrous hypothyroidism 7 and hypertension. Orthologous to human TRHR (thyrotropin releasing hormone receptor); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH (+)-pilocarpine; 2,2',4,4',5,5'-hexachlorobiphenyl; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: thyroliberin receptor; thyrotropin-releasing hormone receptor; TRH-R
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Is Marker For: Strains:   SS.LEW-(D7Rat73-D7Rat128)/Ayd   LEW.SS-(D7Rat73-D7Rat128)/Ayd  
Candidate Gene For: Ept7
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2775,348,672 - 75,393,310 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl775,348,672 - 75,393,309 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx777,174,030 - 77,218,735 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0779,376,541 - 79,421,226 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0779,269,664 - 79,314,345 (+)NCBIRnor_WKY
Rnor_6.0783,113,641 - 83,153,520 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl783,113,672 - 83,153,519 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0783,121,134 - 83,161,215 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4780,050,671 - 80,095,991 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1780,071,435 - 80,116,717 (+)NCBI
Celera772,334,405 - 72,378,742 (+)NCBICelera
Cytogenetic Map7q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Cloning and expression of the thyrotropin-releasing hormone receptor from GH3 rat anterior pituitary cells. de la Pena P, etal., Biochem J 1992 Jun 15;284 ( Pt 3):891-9.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Estradiol transcriptionally and posttranscriptionally up-regulates thyrotropin-releasing hormone receptor messenger ribonucleic acid in rat pituitary cells. Kimura N, etal., Endocrinology 1994 Jan;134(1):432-40.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. A truncated isoform of the thyrotropin-releasing hormone receptor is expressed in the rat central nervous system as well as in the pituitary gland. Satoh T, etal., Brain Res Mol Brain Res 1993 Dec;20(4):353-6.
12. Functional expression and molecular characterization of the thyrotrophin-releasing hormone receptor from the rat anterior pituitary gland. Sellar RE, etal., J Mol Endocrinol 1993 Apr;10(2):199-206.
13. Antisense to thyrotropin releasing hormone receptor reduces arterial blood pressure in spontaneously hypertensive rats. Suzuki S, etal., Circ Res. 1995 Oct;77(4):679-83.
14. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
15. Dimerization and phosphorylation of thyrotropin-releasing hormone receptors are modulated by agonist stimulation. Zhu CC, etal., J Biol Chem 2002 Aug 2;277(31):28228-37.
Additional References at PubMed
PMID:1317787   PMID:1334485   PMID:1338727   PMID:1373613   PMID:8889548   PMID:11278883   PMID:12393857   PMID:15879366   PMID:15905217   PMID:15944919   PMID:16257458   PMID:18795335  
PMID:20691166  


Genomics

Comparative Map Data
Trhr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2775,348,672 - 75,393,310 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl775,348,672 - 75,393,309 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx777,174,030 - 77,218,735 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0779,376,541 - 79,421,226 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0779,269,664 - 79,314,345 (+)NCBIRnor_WKY
Rnor_6.0783,113,641 - 83,153,520 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl783,113,672 - 83,153,519 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0783,121,134 - 83,161,215 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4780,050,671 - 80,095,991 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1780,071,435 - 80,116,717 (+)NCBI
Celera772,334,405 - 72,378,742 (+)NCBICelera
Cytogenetic Map7q31NCBI
TRHR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388109,086,585 - 109,121,565 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl8109,086,585 - 109,121,565 (+)EnsemblGRCh38hg38GRCh38
GRCh378110,098,814 - 110,133,794 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368110,168,900 - 110,200,989 (+)NCBINCBI36Build 36hg18NCBI36
Build 348110,168,901 - 110,200,989NCBI
Celera8106,287,347 - 106,319,484 (+)NCBICelera
Cytogenetic Map8q23.1NCBI
HuRef8105,421,383 - 105,453,868 (+)NCBIHuRef
CHM1_18110,139,931 - 110,172,069 (+)NCBICHM1_1
T2T-CHM13v2.08110,215,119 - 110,250,098 (+)NCBIT2T-CHM13v2.0
Trhr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391544,059,314 - 44,099,308 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1544,059,531 - 44,099,308 (+)EnsemblGRCm39 Ensembl
GRCm381544,195,924 - 44,235,912 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1544,196,135 - 44,235,912 (+)EnsemblGRCm38mm10GRCm38
MGSCv371544,027,681 - 44,067,458 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361544,026,307 - 44,065,986 (+)NCBIMGSCv36mm8
Celera1544,658,539 - 44,700,386 (+)NCBICelera
Cytogenetic Map15B3.2NCBI
cM Map1516.82NCBI
Trhr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541716,529,293 - 16,565,359 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541716,529,293 - 16,565,359 (+)NCBIChiLan1.0ChiLan1.0
TRHR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.18107,886,593 - 107,918,825 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8107,886,593 - 107,918,825 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v08105,739,651 - 105,780,470 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
TRHR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1139,642,565 - 9,681,778 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl139,642,387 - 9,674,831 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha139,626,666 - 9,666,386 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0139,923,346 - 9,963,040 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl139,923,867 - 9,956,094 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1139,666,106 - 9,705,368 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0139,782,697 - 9,821,730 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0139,871,822 - 9,911,555 (+)NCBIUU_Cfam_GSD_1.0
Trhr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530328,375,898 - 28,418,063 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647035,806,397 - 35,844,267 (-)EnsemblSpeTri2.0
SpeTri2.0NW_00493647035,808,569 - 35,844,062 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRHR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl428,436,758 - 28,482,893 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1428,480,637 - 28,482,031 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2430,819,213 - 31,155,972 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TRHR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18103,798,423 - 103,835,284 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8103,800,175 - 103,831,628 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603936,743,423 - 36,777,184 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trhr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247638,192,356 - 8,258,958 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247638,191,550 - 8,255,274 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Trhr
329 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:227
Count of miRNA genes:144
Interacting mature miRNAs:180
Transcripts:ENSRNOT00000006783
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73111283276112832Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73429328279293282Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73429328279293282Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73796056982960569Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)74278731487787314Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74659007091590070Rat
2293696Bmd32Bone mineral density QTL 325.10.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)74765143992651439Rat
2293707Bss32Bone structure and strength QTL 327.640.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)74765143992651439Rat
2300178Bmd54Bone mineral density QTL 545.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)74765143992651439Rat
2293644Bmd29Bone mineral density QTL 295.40.0001femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)74765143992651439Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat
2293685Bmd21Bone mineral density QTL 214.20.0003femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)74765143992651439Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)753612714103945643Rat
2317035Aia16Adjuvant induced arthritis QTL 162.71joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)759238038104238038Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)761074194106074194Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)762004452101773158Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)762004452101773158Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat

Markers in Region
RH144005  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2775,392,973 - 75,393,255 (+)MAPPERmRatBN7.2
Rnor_6.0783,153,184 - 83,153,465NCBIRnor6.0
Rnor_5.0783,160,879 - 83,161,160UniSTSRnor5.0
RGSC_v3.4780,095,655 - 80,095,936UniSTSRGSC3.4
Celera772,378,406 - 72,378,687UniSTS
RH 3.4 Map7516.6UniSTS
Cytogenetic Map7q31UniSTS


Related Rat Strains
The following Strains have been annotated to Trhr


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 6 6 46 10 4
Below cutoff 1 14 8 3 8 2 2 22 9 22 6 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000006783   ⟹   ENSRNOP00000006783
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl775,348,672 - 75,393,309 (+)Ensembl
Rnor_6.0 Ensembl783,113,672 - 83,153,519 (+)Ensembl
RefSeq Acc Id: NM_013047   ⟹   NP_037179
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2775,348,672 - 75,393,310 (+)NCBI
Rnor_6.0783,113,672 - 83,153,520 (+)NCBI
Rnor_5.0783,121,134 - 83,161,215 (+)NCBI
RGSC_v3.4780,050,671 - 80,095,991 (+)RGD
Celera772,334,405 - 72,378,742 (+)RGD
Sequence:
Reference Sequences
RefSeq Acc Id: NP_037179   ⟸   NM_013047
- UniProtKB: Q63949 (UniProtKB/Swiss-Prot),   Q01717 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000006783   ⟸   ENSRNOT00000006783
Protein Domains
G_PROTEIN_RECEP_F1_2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q01717-F1-model_v2 AlphaFold Q01717 1-412 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3904 AgrOrtholog
BioCyc Gene G2FUF-33484 BioCyc
Ensembl Genes ENSRNOG00000005048 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000006783 ENTREZGENE
  ENSRNOP00000006783.4 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006783 ENTREZGENE
  ENSRNOT00000006783.6 UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRH_rcpt_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25570 UniProtKB/Swiss-Prot
NCBI Gene 25570 ENTREZGENE
PANTHER PTHR46061 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Trhr PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  THYROLIBRINR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRHRFAMILY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC218150
UniProt G3V6M9_RAT UniProtKB/TrEMBL
  Q01717 ENTREZGENE
  Q63949 ENTREZGENE
  TRFR_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q63948 UniProtKB/Swiss-Prot
  Q63949 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Trhr  Thyrotropin releasing hormone receptor      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_protein forms monomers and dimers 730055
gene_regulation receptor dimerization and phosphorylation increases in the presence of thyrotropin-releasing hormone 730055