Or6c70 (olfactory receptor family 6 subfamily C member 70) - Rat Genome Database

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Gene: Or6c70 (olfactory receptor family 6 subfamily C member 70) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or6c70 (Ensembl: Olr1057)
Name: olfactory receptor family 6 subfamily C member 70 (Ensembl:olfactory receptor 1057)
RGD ID: 1333260
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane. Orthologous to human OR6C70 (olfactory receptor family 6 subfamily C member 70).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: olfactory receptor 931; olfactory receptor gene Olr931; olfactory receptor Olr931; Olr931
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr873,751,582 - 3,752,520 (+)NCBIGRCr8
mRatBN7.273,102,570 - 3,103,508 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl73,102,570 - 3,103,508 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx75,965,674 - 5,966,612 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.077,841,338 - 7,842,276 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
Rnor_6.0716,404,763 - 16,405,701 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl716,404,755 - 16,405,751 (+)EnsemblRnor6.0rn6Rnor6.0
RGSC_v3.474,367,041 - 4,367,979 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.174,367,040 - 4,367,979 (+)NCBI
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.

Genomics

Variants

.
Variants in Or6c70
18 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:15
Count of miRNA genes:15
Interacting mature miRNAs:15
Transcripts:ENSRNOT00000044977
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
2 5 5 8 24 24 12 16 12 49 29 1 2 6 12

Sequence


Ensembl Acc Id: ENSRNOT00000044977   ⟹   ENSRNOP00000043977
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl73,102,570 - 3,103,508 (+)Ensembl
RefSeq Acc Id: NM_001000704   ⟹   NP_001000704
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr873,751,582 - 3,752,520 (+)NCBI
mRatBN7.273,102,570 - 3,103,508 (+)NCBI
Rnor_6.0716,404,763 - 16,405,701 (+)NCBI
RGSC_v3.474,367,041 - 4,367,979 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000704 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000043977.3
RefSeq Acc Id: NP_001000704   ⟸   NM_001000704
- UniProtKB: D3ZBF0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000043977   ⟸   ENSRNOT00000044977
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZBF0-F1-model_v2 AlphaFold D3ZBF0 1-312 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333260 AgrOrtholog
BioCyc Gene G2FUF-35253 BioCyc
Ensembl Genes ENSRNOG00000047264 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000044977.5 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfact_rcpt_6C-like UniProtKB/TrEMBL
KEGG Report rno:404943 UniProtKB/TrEMBL
NCBI Gene 404943 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 6C70 UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or6c70 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000047264 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt D3ZBF0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or6c70  olfactory receptor family 6 subfamily C member 70  Olr931  olfactory receptor 931  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr931  olfactory receptor 931   Olr931_predicted  olfactory receptor 931 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr931_predicted  olfactory receptor 931 (predicted)      Symbol and Name status set to approved 70820 APPROVED