(+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of MKNK2 mRNA] CTD PMID:31150632 (-)-demecolcine increases expression ISO MKNK2 (Homo sapiens) 6480464 Demecolcine results in increased expression of MKNK2 mRNA CTD PMID:23649840 (1->4)-beta-D-glucan multiple interactions ISO Mknk2 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of MKNK2 mRNA CTD PMID:36331819 1,2-dichloroethane decreases expression ISO Mknk2 (Mus musculus) 6480464 ethylene dichloride results in decreased expression of MKNK2 mRNA CTD PMID:28189721 and PMID:28960355 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of MKNK2 mRNA CTD PMID:30723492 17alpha-ethynylestradiol increases expression ISO Mknk2 (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of MKNK2 mRNA CTD PMID:17942748 17beta-estradiol increases expression ISO Mknk2 (Mus musculus) 6480464 Estradiol results in increased expression of MKNK2 mRNA CTD PMID:15289156 17beta-estradiol decreases expression ISO MKNK2 (Homo sapiens) 6480464 Estradiol results in decreased expression of MKNK2 mRNA CTD PMID:31614463 17beta-estradiol multiple interactions ISO MKNK2 (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of MKNK2 mRNA CTD PMID:30165855 17beta-estradiol increases expression ISO MKNK2 (Homo sapiens) 6480464 Estradiol results in increased expression of MKNK2 mRNA CTD PMID:23019147 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of MKNK2 mRNA CTD PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Mknk2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of MKNK2 mRNA CTD PMID:21570461 2-hydroxypropanoic acid decreases expression ISO MKNK2 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of MKNK2 mRNA CTD PMID:30851411 3,4-methylenedioxymethamphetamine decreases expression ISO Mknk2 (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of MKNK2 mRNA CTD PMID:20188158 4,4'-sulfonyldiphenol decreases expression ISO Mknk2 (Mus musculus) 6480464 bisphenol S results in decreased expression of MKNK2 mRNA CTD PMID:33297965 5-aza-2'-deoxycytidine affects expression ISO MKNK2 (Homo sapiens) 6480464 Decitabine affects the expression of MKNK2 mRNA CTD PMID:23300844 amosite asbestos decreases methylation ISO MKNK2 (Homo sapiens) 6480464 Asbestos and Amosite results in decreased methylation of MKNK2 promoter CTD PMID:29626692 arsane multiple interactions ISO MKNK2 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of MKNK2 mRNA CTD PMID:32525701 arsenic atom multiple interactions ISO MKNK2 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of MKNK2 mRNA CTD PMID:32525701 arsenous acid decreases response to substance ISO MKNK2 (Homo sapiens) 6480464 MKNK2 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:18299328 arsenous acid multiple interactions ISO MKNK2 (Homo sapiens) 6480464 Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MKNK2 protein more ... CTD PMID:18299328 atrazine increases expression ISO MKNK2 (Homo sapiens) 6480464 Atrazine results in increased expression of MKNK2 mRNA CTD PMID:22378314 atrazine affects methylation EXP 6480464 Atrazine affects the methylation of MKNK2 gene CTD PMID:35440735 benzo[a]pyrene multiple interactions ISO Mknk2 (Mus musculus) 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to MKNK2 promoter] CTD PMID:19654925 benzo[e]pyrene decreases methylation ISO MKNK2 (Homo sapiens) 6480464 benzo(e)pyrene results in decreased methylation of MKNK2 3' UTR CTD PMID:30157460 beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MKNK2 mRNA CTD PMID:18164116 bisphenol A increases expression ISO MKNK2 (Homo sapiens) 6480464 bisphenol A results in increased expression of MKNK2 mRNA CTD PMID:25047013 and PMID:29275510 bisphenol A increases expression ISO Mknk2 (Mus musculus) 6480464 bisphenol A results in increased expression of MKNK2 mRNA CTD PMID:32156529 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of MKNK2 mRNA CTD PMID:34947998 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of MKNK2 mRNA CTD PMID:32145629 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of MKNK2 mRNA CTD PMID:25181051 bromobenzene decreases expression EXP 6480464 bromobenzene results in decreased expression of MKNK2 mRNA CTD PMID:32479839 cadmium dichloride decreases methylation EXP 6480464 Cadmium Chloride results in decreased methylation of MKNK2 promoter CTD PMID:22457795 carbamazepine affects expression ISO MKNK2 (Homo sapiens) 6480464 Carbamazepine affects the expression of MKNK2 mRNA CTD PMID:24752500 carbon nanotube decreases expression ISO Mknk2 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 and PMID:25620056 chlordecone decreases expression ISO Mknk2 (Mus musculus) 6480464 Chlordecone results in decreased expression of MKNK2 mRNA CTD PMID:33711761 chlorpyrifos increases expression ISO Mknk2 (Mus musculus) 6480464 Chlorpyrifos results in increased expression of MKNK2 mRNA CTD PMID:37019170 ciguatoxin CTX1B affects expression ISO Mknk2 (Mus musculus) 6480464 Ciguatoxins affects the expression of MKNK2 mRNA CTD PMID:18353800 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of MKNK2 mRNA CTD PMID:21993003 cisplatin affects expression ISO MKNK2 (Homo sapiens) 6480464 Cisplatin affects the expression of MKNK2 mRNA CTD PMID:23300844 cisplatin multiple interactions EXP 6480464 Oxytocin inhibits the reaction [Cisplatin results in increased expression of MKNK2 mRNA] CTD PMID:21993003 clofibrate decreases expression ISO Mknk2 (Mus musculus) 6480464 Clofibrate results in decreased expression of MKNK2 mRNA CTD PMID:17585979 cobalt dichloride increases expression ISO MKNK2 (Homo sapiens) 6480464 cobaltous chloride results in increased expression of MKNK2 mRNA CTD PMID:19376846 copper atom multiple interactions ISO MKNK2 (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of MKNK2 mRNA CTD PMID:30911355 copper(0) multiple interactions ISO MKNK2 (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of MKNK2 mRNA CTD PMID:30911355 copper(II) sulfate increases expression ISO MKNK2 (Homo sapiens) 6480464 Copper Sulfate results in increased expression of MKNK2 mRNA CTD PMID:19549813 coumestrol decreases expression ISO MKNK2 (Homo sapiens) 6480464 Coumestrol results in decreased expression of MKNK2 mRNA CTD PMID:19167446 coumestrol multiple interactions ISO MKNK2 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of MKNK2 mRNA CTD PMID:19167446 crocidolite asbestos decreases methylation ISO MKNK2 (Homo sapiens) 6480464 Asbestos and Crocidolite results in decreased methylation of MKNK2 promoter CTD PMID:29626692 cyclosporin A increases expression ISO MKNK2 (Homo sapiens) 6480464 Cyclosporine results in increased expression of MKNK2 mRNA CTD PMID:25562108 and PMID:27989131 deoxynivalenol affects phosphorylation ISO Mknk2 (Mus musculus) 6480464 deoxynivalenol affects the phosphorylation of MKNK2 protein CTD PMID:23811945 deoxynivalenol decreases expression ISO MKNK2 (Homo sapiens) 6480464 deoxynivalenol results in decreased expression of MKNK2 mRNA CTD PMID:31863870 dexamethasone increases expression ISO Mknk2 (Mus musculus) 6480464 Dexamethasone results in increased expression of MKNK2 mRNA CTD PMID:22733784 dexamethasone increases expression ISO MKNK2 (Homo sapiens) 6480464 Dexamethasone results in increased expression of MKNK2 mRNA CTD PMID:25047013 diarsenic trioxide decreases response to substance ISO MKNK2 (Homo sapiens) 6480464 MKNK2 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:18299328 diarsenic trioxide multiple interactions ISO MKNK2 (Homo sapiens) 6480464 Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MKNK2 protein more ... CTD PMID:18299328 dibenz[a,h]anthracene increases expression ISO Mknk2 (Mus musculus) 6480464 1 more ... CTD PMID:26377693 diclofenac affects expression ISO MKNK2 (Homo sapiens) 6480464 Diclofenac affects the expression of MKNK2 mRNA CTD PMID:24752500 diethyl maleate decreases expression EXP 6480464 diethyl maleate results in decreased expression of MKNK2 mRNA CTD PMID:21161181 diethylstilbestrol increases expression ISO Mknk2 (Mus musculus) 6480464 Diethylstilbestrol results in increased expression of MKNK2 mRNA CTD PMID:15289156 dioxygen increases expression ISO MKNK2 (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of MKNK2 mRNA CTD PMID:20042640 dioxygen multiple interactions ISO Mknk2 (Mus musculus) 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of MKNK2 mRNA CTD PMID:30529165 diquat increases expression ISO Mknk2 (Mus musculus) 6480464 Diquat results in increased expression of MKNK2 mRNA CTD PMID:36851058 disodium selenite increases expression ISO MKNK2 (Homo sapiens) 6480464 Sodium Selenite results in increased expression of MKNK2 mRNA CTD PMID:24383545 Enterolactone multiple interactions ISO MKNK2 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of MKNK2 mRNA CTD PMID:19167446 epoxiconazole decreases expression ISO Mknk2 (Mus musculus) 6480464 epoxiconazole results in decreased expression of MKNK2 mRNA CTD PMID:35436446 ethanol decreases expression ISO Mknk2 (Mus musculus) 6480464 Ethanol results in decreased expression of MKNK2 mRNA CTD PMID:15513904 FR900359 decreases phosphorylation ISO MKNK2 (Homo sapiens) 6480464 FR900359 results in decreased phosphorylation of MKNK2 protein CTD PMID:37730182 furan increases expression EXP 6480464 furan results in increased expression of MKNK2 mRNA CTD PMID:26194646 genistein increases expression ISO Mknk2 (Mus musculus) 6480464 Genistein results in increased expression of MKNK2 mRNA CTD PMID:15289156 genistein increases expression ISO MKNK2 (Homo sapiens) 6480464 Genistein results in increased expression of MKNK2 mRNA CTD PMID:22228119 glyphosate increases expression ISO MKNK2 (Homo sapiens) 6480464 Glyphosate results in increased expression of MKNK2 mRNA CTD PMID:31295307 isoprenaline increases expression ISO Mknk2 (Mus musculus) 6480464 Isoproterenol results in increased expression of MKNK2 mRNA CTD PMID:20003209 lead diacetate decreases expression ISO Mknk2 (Mus musculus) 6480464 lead acetate results in decreased expression of MKNK2 mRNA CTD PMID:25270620 methapyrilene decreases methylation ISO MKNK2 (Homo sapiens) 6480464 Methapyrilene results in decreased methylation of MKNK2 3' UTR CTD PMID:30157460 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MKNK2 mRNA CTD PMID:18164116 nefazodone decreases expression EXP 6480464 nefazodone results in decreased expression of MKNK2 mRNA CTD PMID:24136188 niclosamide increases expression ISO MKNK2 (Homo sapiens) 6480464 Niclosamide results in increased expression of MKNK2 mRNA CTD PMID:36318118 Nor-9-carboxy-delta9-THC multiple interactions ISO MKNK2 (Homo sapiens) 6480464 [Cannabinoids results in increased abundance of 11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid] which affects the methylation of MKNK2 gene CTD PMID:30521419 orphenadrine affects expression EXP 6480464 Orphenadrine affects the expression of MKNK2 mRNA CTD PMID:23665939 oxytocin multiple interactions EXP 6480464 Oxytocin inhibits the reaction [Cisplatin results in increased expression of MKNK2 mRNA] CTD PMID:21993003 ozone multiple interactions ISO MKNK2 (Homo sapiens) 6480464 [Air Pollutants results in increased abundance of Ozone] which affects the expression of MKNK2 mRNA CTD PMID:35430440 p-toluidine increases expression EXP 6480464 4-toluidine results in increased expression of MKNK2 mRNA CTD PMID:27638505 paracetamol affects expression ISO Mknk2 (Mus musculus) 6480464 Acetaminophen affects the expression of MKNK2 mRNA CTD PMID:15606129 and PMID:17562736 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of MKNK2 mRNA CTD PMID:33387578 paracetamol increases expression ISO MKNK2 (Homo sapiens) 6480464 Acetaminophen results in increased expression of MKNK2 mRNA CTD PMID:21420995 and PMID:29067470 parathion increases expression ISO Mknk2 (Mus musculus) 6480464 Parathion results in increased expression of MKNK2 mRNA CTD PMID:34813904 perfluorononanoic acid increases expression ISO MKNK2 (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in increased expression of MKNK2 mRNA CTD PMID:32588087 perfluorooctane-1-sulfonic acid multiple interactions ISO Mknk2 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of MKNK2 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of MKNK2 mRNA CTD PMID:36331819 phenformin decreases expression EXP 6480464 Phenformin results in decreased expression of MKNK2 mRNA CTD PMID:31324951 phenobarbital multiple interactions ISO Mknk2 (Mus musculus) 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of MKNK2 mRNA] CTD PMID:19482888 phenobarbital increases expression ISO Mknk2 (Mus musculus) 6480464 Phenobarbital results in increased expression of MKNK2 mRNA CTD PMID:19270015 and PMID:19482888 PhIP increases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased expression of MKNK2 mRNA CTD PMID:15215175 progesterone increases expression ISO MKNK2 (Homo sapiens) 6480464 Progesterone results in increased expression of MKNK2 mRNA CTD PMID:18037150 quercetin decreases expression ISO MKNK2 (Homo sapiens) 6480464 Quercetin results in decreased expression of MKNK2 mRNA CTD PMID:21632981 quercetin increases expression ISO MKNK2 (Homo sapiens) 6480464 Quercetin results in increased expression of MKNK2 mRNA CTD PMID:30152185 rac-lactic acid decreases expression ISO MKNK2 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of MKNK2 mRNA CTD PMID:30851411 resveratrol multiple interactions ISO MKNK2 (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of MKNK2 mRNA CTD PMID:23557933 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of MKNK2 mRNA CTD PMID:28374803 serpentine asbestos decreases methylation ISO MKNK2 (Homo sapiens) 6480464 Asbestos and Serpentine results in decreased methylation of MKNK2 promoter CTD PMID:29626692 sodium arsenate multiple interactions ISO MKNK2 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of MKNK2 mRNA CTD PMID:32525701 sodium arsenite decreases expression ISO MKNK2 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of MKNK2 mRNA CTD PMID:28595984 sodium arsenite affects expression ISO MKNK2 (Homo sapiens) 6480464 sodium arsenite affects the expression of MKNK2 mRNA CTD PMID:29319823 and PMID:34032870 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of MKNK2 mRNA CTD PMID:25905778 sunitinib increases expression ISO MKNK2 (Homo sapiens) 6480464 Sunitinib results in increased expression of MKNK2 mRNA CTD PMID:31533062 T-2 toxin decreases expression ISO MKNK2 (Homo sapiens) 6480464 T-2 Toxin results in decreased expression of MKNK2 mRNA CTD PMID:31863870 tert-butyl hydroperoxide decreases expression ISO MKNK2 (Homo sapiens) 6480464 tert-Butylhydroperoxide results in decreased expression of MKNK2 mRNA CTD PMID:15336504 tert-butyl hydroperoxide increases expression ISO Mknk2 (Mus musculus) 6480464 tert-Butylhydroperoxide results in increased expression of MKNK2 mRNA CTD PMID:15003993 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of MKNK2 mRNA CTD PMID:31150632 tetrachloromethane increases expression ISO Mknk2 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of MKNK2 mRNA CTD PMID:31919559 tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of MKNK2 mRNA] CTD PMID:31150632 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of MKNK2 mRNA CTD PMID:34492290 topotecan affects response to substance ISO MKNK2 (Homo sapiens) 6480464 MKNK2 protein affects the susceptibility to Topotecan CTD PMID:16217747 trichostatin A affects expression ISO MKNK2 (Homo sapiens) 6480464 trichostatin A affects the expression of MKNK2 mRNA CTD PMID:28542535 triphenyl phosphate affects expression EXP 6480464 triphenyl phosphate affects the expression of MKNK2 mRNA CTD PMID:30589522 triptonide increases expression ISO Mknk2 (Mus musculus) 6480464 triptonide results in increased expression of MKNK2 mRNA CTD PMID:33045310 urethane increases expression ISO MKNK2 (Homo sapiens) 6480464 Urethane results in increased expression of MKNK2 mRNA CTD PMID:28818685 valdecoxib decreases expression EXP 6480464 valdecoxib results in decreased expression of MKNK2 mRNA CTD PMID:24136188 valproic acid increases methylation ISO MKNK2 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of MKNK2 gene CTD PMID:29154799 valproic acid affects expression ISO MKNK2 (Homo sapiens) 6480464 Valproic Acid affects the expression of MKNK2 mRNA CTD PMID:25979313 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of MKNK2 mRNA CTD PMID:23034163 vincristine increases expression ISO MKNK2 (Homo sapiens) 6480464 Vincristine results in increased expression of MKNK2 mRNA CTD PMID:23649840 vorinostat decreases expression ISO MKNK2 (Homo sapiens) 6480464 vorinostat results in decreased expression of MKNK2 mRNA CTD PMID:27188386