Cnot2 (CCR4-NOT transcription complex, subunit 2) - Rat Genome Database

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Gene: Cnot2 (CCR4-NOT transcription complex, subunit 2) Rattus norvegicus
Analyze
Symbol: Cnot2
Name: CCR4-NOT transcription complex, subunit 2
RGD ID: 1311672
Description: Predicted to enable transcription corepressor binding activity. Predicted to contribute to poly(A)-specific ribonuclease activity. Predicted to be involved in several processes, including negative regulation of intracellular estrogen receptor signaling pathway; negative regulation of macromolecule biosynthetic process; and positive regulation of cytoplasmic mRNA processing body assembly. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be part of CCR4-NOT core complex. Predicted to be active in P-body. Orthologous to human CNOT2 (CCR4-NOT transcription complex subunit 2); PARTICIPATES IN microRNA pathway; RNA degradation pathway; INTERACTS WITH 2,6-dinitrotoluene; bisphenol A; Brodifacoum.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CCR4-NOT transcription complex subunit 2; LOC299805
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2752,130,444 - 52,222,338 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl752,130,441 - 52,223,575 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx754,037,151 - 54,128,665 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0756,240,245 - 56,331,759 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0756,018,227 - 56,109,741 (-)NCBIRnor_WKY
Rnor_6.0759,526,105 - 59,617,307 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl759,527,124 - 59,587,385 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0759,537,579 - 59,628,786 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4755,823,982 - 55,880,812 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1755,844,724 - 55,901,542 (-)NCBI
Celera748,914,667 - 48,971,519 (-)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. RNA decay machines: deadenylation by the Ccr4-not and Pan2-Pan3 complexes. Wahle E and Winkler GS, Biochim Biophys Acta. 2013 Jun-Jul;1829(6-7):561-70. doi: 10.1016/j.bbagrm.2013.01.003. Epub 2013 Jan 19.
Additional References at PubMed
PMID:12477932   PMID:14707134   PMID:16712523   PMID:16778766   PMID:19558367   PMID:19946888   PMID:21299754   PMID:22367759  


Genomics

Comparative Map Data
Cnot2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2752,130,444 - 52,222,338 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl752,130,441 - 52,223,575 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx754,037,151 - 54,128,665 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0756,240,245 - 56,331,759 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0756,018,227 - 56,109,741 (-)NCBIRnor_WKY
Rnor_6.0759,526,105 - 59,617,307 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl759,527,124 - 59,587,385 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0759,537,579 - 59,628,786 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4755,823,982 - 55,880,812 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1755,844,724 - 55,901,542 (-)NCBI
Celera748,914,667 - 48,971,519 (-)NCBICelera
Cytogenetic Map7q22NCBI
CNOT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381270,243,018 - 70,354,993 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1270,243,002 - 70,354,993 (+)EnsemblGRCh38hg38GRCh38
GRCh371270,636,798 - 70,748,773 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361268,923,044 - 69,035,040 (+)NCBINCBI36Build 36hg18NCBI36
Build 341268,923,488 - 69,033,960NCBI
Celera1270,300,448 - 70,412,447 (+)NCBICelera
Cytogenetic Map12q15NCBI
HuRef1267,686,934 - 67,798,932 (+)NCBIHuRef
CHM1_11270,606,077 - 70,718,081 (+)NCBICHM1_1
T2T-CHM13v2.01270,222,411 - 70,334,463 (+)NCBIT2T-CHM13v2.0
Cnot2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910116,321,065 - 116,418,891 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10116,321,066 - 116,417,416 (-)EnsemblGRCm39 Ensembl
GRCm3810116,485,160 - 116,581,900 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10116,485,161 - 116,581,511 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710115,922,217 - 116,018,567 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610115,889,276 - 115,985,621 (-)NCBIMGSCv36mm8
Celera10118,426,741 - 118,523,052 (-)NCBICelera
Cytogenetic Map10D2NCBI
Cnot2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540510,451,414 - 10,547,229 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540510,451,414 - 10,547,229 (+)NCBIChiLan1.0ChiLan1.0
CNOT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11270,520,722 - 70,633,149 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1270,520,722 - 70,633,149 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01267,753,703 - 67,865,375 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
CNOT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11012,057,269 - 12,174,405 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1012,009,762 - 12,172,427 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1011,995,863 - 12,112,451 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01012,188,879 - 12,305,324 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1012,141,268 - 12,305,312 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11012,055,404 - 12,171,985 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01012,302,721 - 12,419,265 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01012,426,002 - 12,542,252 (+)NCBIUU_Cfam_GSD_1.0
Cnot2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494546,069,715 - 46,170,762 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365457,938,934 - 8,042,117 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049365457,938,934 - 8,040,409 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNOT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl534,426,394 - 34,549,310 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1534,470,911 - 34,548,968 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2537,132,108 - 37,207,783 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CNOT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11165,823,294 - 65,932,588 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1165,861,353 - 65,934,042 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037179,752,841 - 179,862,945 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cnot2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475027,430,575 - 27,529,081 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475027,433,671 - 27,529,545 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cnot2
203 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:157
Count of miRNA genes:124
Interacting mature miRNAs:134
Transcripts:ENSRNOT00000066396
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat
1354639Spl5Serum phospholipid level QTL 53.9blood LDL phospholipid amount (VT:0010505)blood low density lipoprotein phospholipid level (CMO:0001568)71965431752888450Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72673740163902784Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)72940968353612950Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)72940968374409683Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73111283276112832Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73429328279293282Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73429328279293282Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73796056982960569Rat
2303629Vencon3Ventilatory control QTL 37.25respiration trait (VT:0001943)respiration rate (CMO:0000289)74110969256793354Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)74278731487787314Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74659007091590070Rat
10059605Kidm47Kidney mass QTL 472.910.05kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)74725178365728867Rat
2293696Bmd32Bone mineral density QTL 325.10.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)74765143992651439Rat
2293707Bss32Bone structure and strength QTL 327.640.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)74765143992651439Rat
2300178Bmd54Bone mineral density QTL 545.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)74765143992651439Rat
2293644Bmd29Bone mineral density QTL 295.40.0001femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)74765143992651439Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat
2293685Bmd21Bone mineral density QTL 214.20.0003femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)74765143992651439Rat

Markers in Region
RH144030  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2752,138,261 - 52,138,425 (+)MAPPERmRatBN7.2
Rnor_6.0759,533,922 - 59,534,085NCBIRnor6.0
Rnor_5.0759,545,396 - 59,545,559UniSTSRnor5.0
RGSC_v3.4755,827,349 - 55,827,512UniSTSRGSC3.4
Celera748,918,034 - 48,918,197UniSTS
RH 3.4 Map7481.5UniSTS
Cytogenetic Map7q22UniSTS
RH140338  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2752,149,611 - 52,149,762 (+)MAPPERmRatBN7.2
Rnor_6.0759,545,272 - 59,545,422NCBIRnor6.0
Rnor_5.0759,556,746 - 59,556,896UniSTSRnor5.0
RGSC_v3.4755,838,699 - 55,838,849UniSTSRGSC3.4
Celera748,929,384 - 48,929,534UniSTS
RH 3.4 Map7503.6UniSTS
Cytogenetic Map7q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 10 74 35 41 11 8
Low 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001011988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001399553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001399554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001399555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001399556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078717 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005486575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC136025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC136231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC087653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000066396   ⟹   ENSRNOP00000061277
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl752,134,908 - 52,191,729 (-)Ensembl
Rnor_6.0 Ensembl759,530,568 - 59,587,385 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000085836   ⟹   ENSRNOP00000075690
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl752,131,074 - 52,221,608 (-)Ensembl
Rnor_6.0 Ensembl759,532,641 - 59,547,174 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000091427   ⟹   ENSRNOP00000074023
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl752,136,860 - 52,221,617 (-)Ensembl
Rnor_6.0 Ensembl759,527,124 - 59,587,382 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100132   ⟹   ENSRNOP00000078367
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl752,130,594 - 52,221,611 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000104908   ⟹   ENSRNOP00000084380
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl752,130,441 - 52,221,617 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000114739   ⟹   ENSRNOP00000077944
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl752,130,443 - 52,221,617 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000118688   ⟹   ENSRNOP00000095291
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl752,130,594 - 52,223,575 (-)Ensembl
RefSeq Acc Id: NM_001011988   ⟹   NP_001011988
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,134,895 - 52,191,729 (-)NCBI
Rnor_6.0759,530,555 - 59,587,385 (-)NCBI
Rnor_5.0759,537,579 - 59,628,786 (-)NCBI
RGSC_v3.4755,823,982 - 55,880,812 (-)RGD
Celera748,914,667 - 48,971,519 (-)RGD
Sequence:
RefSeq Acc Id: XM_006241363   ⟹   XP_006241425
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,130,444 - 52,222,326 (-)NCBI
Rnor_6.0759,526,105 - 59,617,297 (-)NCBI
Rnor_5.0759,537,579 - 59,628,786 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006241364   ⟹   XP_006241426
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,130,453 - 52,222,326 (-)NCBI
Rnor_6.0759,526,105 - 59,617,307 (-)NCBI
Rnor_5.0759,537,579 - 59,628,786 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006241365   ⟹   XP_006241427
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,130,453 - 52,221,608 (-)NCBI
Rnor_6.0759,526,105 - 59,617,307 (-)NCBI
Rnor_5.0759,537,579 - 59,628,786 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006241367   ⟹   XP_006241429
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,130,453 - 52,222,326 (-)NCBI
Rnor_6.0759,526,105 - 59,617,307 (-)NCBI
Rnor_5.0759,537,579 - 59,628,786 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006241369   ⟹   XP_006241431
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,130,453 - 52,222,327 (-)NCBI
Rnor_6.0759,526,105 - 59,617,297 (-)NCBI
Rnor_5.0759,537,579 - 59,628,786 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006241370   ⟹   XP_006241432
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,130,453 - 52,221,617 (-)NCBI
Rnor_6.0759,526,105 - 59,617,307 (-)NCBI
Rnor_5.0759,537,579 - 59,628,786 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594741   ⟹   XP_017450230
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,130,448 - 52,222,327 (-)NCBI
Rnor_6.0759,526,105 - 59,617,307 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039078717   ⟹   XP_038934645
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,130,453 - 52,221,318 (-)NCBI
RefSeq Acc Id: XM_039078718   ⟹   XP_038934646
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,130,453 - 52,211,785 (-)NCBI
RefSeq Acc Id: XM_039078719   ⟹   XP_038934647
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,130,453 - 52,194,904 (-)NCBI
RefSeq Acc Id: XM_039078720   ⟹   XP_038934648
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,130,453 - 52,222,326 (-)NCBI
RefSeq Acc Id: XM_039078722   ⟹   XP_038934650
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,130,453 - 52,191,726 (-)NCBI
RefSeq Acc Id: XM_039078723   ⟹   XP_038934651
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,130,453 - 52,222,326 (-)NCBI
RefSeq Acc Id: XM_039078724   ⟹   XP_038934652
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,130,453 - 52,191,716 (-)NCBI
RefSeq Acc Id: XM_039078725   ⟹   XP_038934653
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,133,513 - 52,222,329 (-)NCBI
RefSeq Acc Id: XM_039078726   ⟹   XP_038934654
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,131,062 - 52,222,328 (-)NCBI
RefSeq Acc Id: XM_039078727   ⟹   XP_038934655
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,131,062 - 52,222,327 (-)NCBI
RefSeq Acc Id: XM_039078728   ⟹   XP_038934656
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,131,062 - 52,222,328 (-)NCBI
RefSeq Acc Id: XM_039078730   ⟹   XP_038934658
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,131,062 - 52,222,327 (-)NCBI
RefSeq Acc Id: XM_039078731   ⟹   XP_038934659
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,131,062 - 52,222,328 (-)NCBI
RefSeq Acc Id: XM_039078732   ⟹   XP_038934660
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,131,062 - 52,222,328 (-)NCBI
RefSeq Acc Id: XM_039078733   ⟹   XP_038934661
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,131,062 - 52,222,325 (-)NCBI
RefSeq Acc Id: XM_039078734   ⟹   XP_038934662
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,131,062 - 52,191,719 (-)NCBI
RefSeq Acc Id: XM_039078735   ⟹   XP_038934663
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,131,062 - 52,145,999 (-)NCBI
RefSeq Acc Id: XR_005486575
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,142,856 - 52,222,338 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001011988 (Get FASTA)   NCBI Sequence Viewer  
  NP_001386482 (Get FASTA)   NCBI Sequence Viewer  
  NP_001386483 (Get FASTA)   NCBI Sequence Viewer  
  NP_001386484 (Get FASTA)   NCBI Sequence Viewer  
  NP_001386485 (Get FASTA)   NCBI Sequence Viewer  
  XP_006241425 (Get FASTA)   NCBI Sequence Viewer  
  XP_006241426 (Get FASTA)   NCBI Sequence Viewer  
  XP_006241427 (Get FASTA)   NCBI Sequence Viewer  
  XP_006241429 (Get FASTA)   NCBI Sequence Viewer  
  XP_006241431 (Get FASTA)   NCBI Sequence Viewer  
  XP_006241432 (Get FASTA)   NCBI Sequence Viewer  
  XP_017450230 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934645 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934646 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934647 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934648 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934650 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934651 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934652 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934653 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934654 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934655 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934656 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934658 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934659 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934660 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934661 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934662 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934663 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH87653 (Get FASTA)   NCBI Sequence Viewer  
  EDM16655 (Get FASTA)   NCBI Sequence Viewer  
  EDM16656 (Get FASTA)   NCBI Sequence Viewer  
  EDM16658 (Get FASTA)   NCBI Sequence Viewer  
  EDM16662 (Get FASTA)   NCBI Sequence Viewer  
  EDM16665 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001011988   ⟸   NM_001011988
- Sequence:
RefSeq Acc Id: XP_006241431   ⟸   XM_006241369
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006241425   ⟸   XM_006241363
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006241432   ⟸   XM_006241370
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_006241426   ⟸   XM_006241364
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K717 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241429   ⟸   XM_006241367
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006241427   ⟸   XM_006241365
- Peptide Label: isoform X3
- UniProtKB: A0A0G2KB82 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450230   ⟸   XM_017594741
- Peptide Label: isoform X6
- UniProtKB: A0A8I5ZXR1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000074023   ⟸   ENSRNOT00000091427
RefSeq Acc Id: ENSRNOP00000061277   ⟸   ENSRNOT00000066396
RefSeq Acc Id: ENSRNOP00000075690   ⟸   ENSRNOT00000085836
RefSeq Acc Id: XP_038934648   ⟸   XM_039078720
- Peptide Label: isoform X3
- UniProtKB: A0A0G2KB82 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038934651   ⟸   XM_039078723
- Peptide Label: isoform X3
- UniProtKB: A0A0G2KB82 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038934645   ⟸   XM_039078717
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038934646   ⟸   XM_039078718
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038934647   ⟸   XM_039078719
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038934650   ⟸   XM_039078722
- Peptide Label: isoform X3
- UniProtKB: A0A0G2KB82 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038934652   ⟸   XM_039078724
- Peptide Label: isoform X3
- UniProtKB: A0A0G2KB82 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038934660   ⟸   XM_039078732
- Peptide Label: isoform X13
RefSeq Acc Id: XP_038934656   ⟸   XM_039078728
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038934654   ⟸   XM_039078726
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038934659   ⟸   XM_039078731
- Peptide Label: isoform X12
RefSeq Acc Id: XP_038934658   ⟸   XM_039078730
- Peptide Label: isoform X11
- UniProtKB: A0A8I5ZKS1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038934655   ⟸   XM_039078727
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038934661   ⟸   XM_039078733
- Peptide Label: isoform X14
RefSeq Acc Id: XP_038934662   ⟸   XM_039078734
- Peptide Label: isoform X14
RefSeq Acc Id: XP_038934663   ⟸   XM_039078735
- Peptide Label: isoform X15
RefSeq Acc Id: XP_038934653   ⟸   XM_039078725
- Peptide Label: isoform X4
RefSeq Acc Id: ENSRNOP00000084380   ⟸   ENSRNOT00000104908
RefSeq Acc Id: ENSRNOP00000095291   ⟸   ENSRNOT00000118688
RefSeq Acc Id: ENSRNOP00000077944   ⟸   ENSRNOT00000114739
RefSeq Acc Id: ENSRNOP00000078367   ⟸   ENSRNOT00000100132
Protein Domains
NOT2_3_5

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K717-F1-model_v2 AlphaFold A0A0G2K717 1-540 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311672 AgrOrtholog
BioCyc Gene G2FUF-34033 BioCyc
Ensembl Genes ENSRNOG00000004909 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000061277.1 UniProtKB/TrEMBL
  ENSRNOP00000074023.2 UniProtKB/TrEMBL
  ENSRNOP00000075690 ENTREZGENE
  ENSRNOP00000075690.2 UniProtKB/TrEMBL
  ENSRNOP00000077944 ENTREZGENE
  ENSRNOP00000077944.1 UniProtKB/TrEMBL
  ENSRNOP00000078367 ENTREZGENE
  ENSRNOP00000078367.1 UniProtKB/TrEMBL
  ENSRNOP00000084380 ENTREZGENE
  ENSRNOP00000084380.1 UniProtKB/TrEMBL
  ENSRNOP00000095291.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000066396.3 UniProtKB/TrEMBL
  ENSRNOT00000085836 ENTREZGENE
  ENSRNOT00000085836.2 UniProtKB/TrEMBL
  ENSRNOT00000091427.2 UniProtKB/TrEMBL
  ENSRNOT00000100132 ENTREZGENE
  ENSRNOT00000100132.1 UniProtKB/TrEMBL
  ENSRNOT00000104908 ENTREZGENE
  ENSRNOT00000104908.1 UniProtKB/TrEMBL
  ENSRNOT00000114739 ENTREZGENE
  ENSRNOT00000114739.1 UniProtKB/TrEMBL
  ENSRNOT00000118688.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.30.1020 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7313082 IMAGE-MGC_LOAD
InterPro CCR4-NOT_su2/3/5_N_sf UniProtKB/TrEMBL
  NOT UniProtKB/TrEMBL
  Not2/3/5 UniProtKB/TrEMBL
KEGG Report rno:299805 UniProtKB/TrEMBL
MGC_CLONE MGC:105588 IMAGE-MGC_LOAD
NCBI Gene 299805 ENTREZGENE
PANTHER PTHR23326 UniProtKB/TrEMBL
Pfam NOT2_3_5 UniProtKB/TrEMBL
PhenoGen Cnot2 PhenoGen
UniProt A0A0G2K717 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2KB82 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y9U2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZKS1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZXR1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AJD1_RAT UniProtKB/TrEMBL
  Q5PPJ8_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Cnot2  CCR4-NOT transcription complex, subunit 2  Cnot2_predicted  CCR4-NOT transcription complex, subunit 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Cnot2_predicted  CCR4-NOT transcription complex, subunit 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED