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Imported Disease Annotations - OMIMTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Preimplantation Embryonic Lethality 1 | | ISO | RGD:1343822 | 7240710 | | OMIM | | |
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Imported Disease Annotations - OMIMTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Preimplantation Embryonic Lethality 1 | | ISO | RGD:1343822 | 7240710 | | OMIM | | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
PMID:16314515 | PMID:18191828 | PMID:18804437 | PMID:19376971 | PMID:26537248 |
Tle6 (Rattus norvegicus - Norway rat) |
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TLE6 (Homo sapiens - human) |
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Tle6 (Mus musculus - house mouse) |
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Tle6 (Chinchilla lanigera - long-tailed chinchilla) |
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TLE6 (Pan paniscus - bonobo/pygmy chimpanzee) |
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TLE6 (Canis lupus familiaris - dog) |
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Tle6 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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TLE6 (Sus scrofa - pig) |
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TLE6 (Chlorocebus sabaeus - green monkey) |
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Tle6 (Heterocephalus glaber - naked mole-rat) |
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Variants in Tle6
60 total Variants ![]() |
The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 4 | 14 | 22 | ||||||||||
Low | 2 | 35 | 31 | 23 | 7 | 23 | 69 | 21 | 19 | 11 | |||
Below cutoff | 1 | 4 | 21 | 18 | 7 | 18 | 8 | 9 | 5 | 8 |
RefSeq Transcripts | XM_006225929 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_006225930 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006225932 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006241027 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006241028 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006241030 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_008776380 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017595152 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017595153 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017603373 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017603374 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017603375 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039080433 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039080434 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | JACYVU010000177 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000008360 ⟹ ENSRNOP00000008360 | ||||||||||||
RefSeq Status: | |||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000109747 ⟹ ENSRNOP00000081779 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_006241027 ⟹ XP_006241089 | ||||||||||||||||
RefSeq Status: | |||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006241030 ⟹ XP_006241092 | ||||||||||||||||
RefSeq Status: | |||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_017595153 ⟹ XP_017450642 | ||||||||||||
RefSeq Status: | |||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039080433 ⟹ XP_038936361 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_039080434 ⟹ XP_038936362 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | XP_006241089 | (Get FASTA) | NCBI Sequence Viewer |
XP_006241092 | (Get FASTA) | NCBI Sequence Viewer | |
XP_017450642 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038936361 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038936362 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | XP_006241092 ⟸ XM_006241030 |
- Peptide Label: | isoform X2 |
- Sequence: |
RefSeq Acc Id: | XP_006241089 ⟸ XM_006241027 |
- Peptide Label: | isoform X1 |
- Sequence: |
RefSeq Acc Id: | XP_017450642 ⟸ XM_017595153 |
- Peptide Label: | isoform X3 |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000008360 ⟸ ENSRNOT00000008360 |
RefSeq Acc Id: | XP_038936361 ⟸ XM_039080433 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_038936362 ⟸ XM_039080434 |
- Peptide Label: | isoform X3 |
RefSeq Acc Id: | ENSRNOP00000081779 ⟸ ENSRNOT00000109747 |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13694971 | ||||||||
Promoter ID: | EPDNEW_R5490 | ||||||||
Type: | single initiation site | ||||||||
Name: | Tle6_1 | ||||||||
Description: | transducin-like enhancer of split 6 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:1561530 | AgrOrtholog |
BioCyc Gene | G2FUF-35042 | BioCyc |
Ensembl Genes | ENSRNOG00000006350 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Protein | ENSRNOP00000008360 | ENTREZGENE |
ENSRNOP00000008360.8 | UniProtKB/TrEMBL | |
ENSRNOP00000081779 | ENTREZGENE | |
ENSRNOP00000081779.1 | UniProtKB/TrEMBL | |
Ensembl Transcript | ENSRNOT00000008360 | ENTREZGENE |
ENSRNOT00000008360.9 | UniProtKB/TrEMBL | |
ENSRNOT00000109747 | ENTREZGENE | |
ENSRNOT00000109747.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 2.130.10.10 | UniProtKB/TrEMBL |
InterPro | Groucho_enhance | UniProtKB/TrEMBL |
Quinoprotein_ADH-like_supfam | UniProtKB/TrEMBL | |
WD40/YVTN_repeat-like_dom | UniProtKB/TrEMBL | |
WD40_repeat | UniProtKB/TrEMBL | |
WD40_repeat_dom_sf | UniProtKB/TrEMBL | |
NCBI Gene | 299637 | ENTREZGENE |
PANTHER | PTHR10814 | UniProtKB/TrEMBL |
Pfam | WD40 | UniProtKB/TrEMBL |
PhenoGen | Tle6 | PhenoGen |
PRINTS | GROUCHOFAMLY | UniProtKB/TrEMBL |
PROSITE | WD_REPEATS_2 | UniProtKB/TrEMBL |
SMART | WD40 | UniProtKB/TrEMBL |
Superfamily-SCOP | SSF50998 | UniProtKB/TrEMBL |
WD40_like | UniProtKB/TrEMBL | |
UniProt | A0A8I5ZVQ7_RAT | UniProtKB/TrEMBL |
F1LXS4_RAT | UniProtKB/TrEMBL |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2018-12-04 | Tle6 | TLE family member 6, subcortical maternal complex member | Tle6 | transducin-like enhancer of split 6 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2014-03-13 | Tle6 | transducin-like enhancer of split 6 | Tle6 | transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2013-11-25 | Tle6 | transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila) | RGD1561530 | similar to Tle6 protein | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-04-30 | RGD1561530 | similar to Tle6 protein | RGD1561530_predicted | similar to Tle6 protein (predicted) | 'predicted' is removed | 2292626 | APPROVED |
2006-03-07 | RGD1561530_predicted | similar to Tle6 protein (predicted) | LOC299637 | similar to Tle6 protein | Symbol and Name status set to approved | 1299863 | APPROVED |
2006-02-09 | LOC299637 | similar to Tle6 protein | Symbol and Name status set to provisional | 70820 | PROVISIONAL |