(+)-pilocarpine increases expression EXP 6480464 Pilocarpine results in increased expression of CDK2 mRNA CTD PMID:17971868 (+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of CDK2 mRNA] CTD PMID:31150632 (-)-demecolcine decreases expression ISO RGD:1352010 6480464 Demecolcine results in decreased expression of CDK2 mRNA CTD PMID:23649840 (20R)-protopanaxadiol increases expression ISO RGD:1352010 6480464 protopanaxadiol results in increased expression of CDK2 mRNA CTD PMID:31805304 (R)-mevalonic acid multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of CDK2 protein] CTD PMID:26577051 (S)-(-)-perillyl alcohol decreases expression ISO RGD:1352010 6480464 perillyl alcohol results in decreased expression of CDK2 protein CTD PMID:17138864 (S)-(-)-perillyl alcohol multiple interactions ISO RGD:1352010 6480464 perillyl alcohol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein], perillyl alcohol promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein] CTD PMID:17138864 (S)-colchicine increases expression EXP 6480464 Colchicine results in increased expression of CDK2 mRNA CTD PMID:18255150 (S)-nicotine multiple interactions ISO RGD:1352010 6480464 CDK2 affects the reaction [Nicotine results in increased phosphorylation of AKT1 protein] CTD PMID:35929799 (Z)-3-butylidenephthalide decreases expression EXP 6480464 butylidenephthalide results in decreased expression of CDK2 protein CTD PMID:16987298 (Z)-3-butylidenephthalide decreases expression ISO RGD:1352010 6480464 butylidenephthalide results in decreased expression of CDK2 protein CTD PMID:16987298 , PMID:23770345 1,2-dichloroethane decreases expression ISO RGD:70501 6480464 ethylene dichloride results in decreased expression of CDK2 mRNA CTD PMID:28189721 , PMID:28960355 1,2-dimethylhydrazine increases expression ISO RGD:70501 6480464 1, 2-Dimethylhydrazine results in increased expression of CDK2 mRNA CTD PMID:22206623 1-(4-methoxybenzyl)-3-(5-nitro-1,3-thiazol-2-yl)urea multiple interactions ISO RGD:1352010 6480464 [N-(4-methoxybenzyl)-N'-(5-nitro-1, 3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CDK2 protein] CTD PMID:20540935 14-Deoxy-11,12-didehydroandrographolide multiple interactions ISO RGD:70501 6480464 14-deoxy-11 more ... CTD PMID:30248417 15-deoxy-Delta(12,14)-prostaglandin J2 decreases expression ISO RGD:1352010 6480464 15-deoxy-delta(12, 14)-prostaglandin J2 results in decreased expression of CDK2 protein CTD PMID:15729575 17beta-estradiol increases expression ISO RGD:70501 6480464 Estradiol results in increased expression of CDK2 mRNA CTD PMID:25210133 17beta-estradiol decreases phosphorylation ISO RGD:1352010 6480464 Estradiol results in decreased phosphorylation of CDK2 protein CTD PMID:28880708 17beta-estradiol decreases expression ISO RGD:1352010 6480464 Estradiol results in decreased expression of CDK2 mRNA CTD PMID:23094148 17beta-estradiol increases expression ISO RGD:1352010 6480464 Estradiol results in increased expression of CDK2 mRNA CTD PMID:16474171 more ... 17beta-estradiol increases activity ISO RGD:1352010 6480464 Estradiol results in increased activity of CDK2 protein CTD PMID:8927716 , PMID:9168006 17beta-estradiol multiple interactions ISO RGD:1352010 6480464 [Estradiol co-treated with IGF1R mutant form] results in decreased expression of CDK2 mRNA more ... CTD PMID:22552626 more ... 17beta-estradiol multiple interactions ISO RGD:70501 6480464 ESR1 protein promotes the reaction [Estradiol results in increased expression of CDK2 mRNA] CTD PMID:25210133 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO RGD:1352010 6480464 Dihydrotestosterone results in increased expression of CDK2 protein CTD PMID:15647840 19-Nor-17alpha-pregn-5(10)-en-20-yne-3alpha,17beta-diol multiple interactions EXP 6480464 17alpha-ethynylestr-5(10)-ene-3alpha, 17beta-diol results in decreased expression of and results in decreased activity of CDK2 protein CTD PMID:16019103 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:70501 6480464 [2 more ... CTD PMID:25510870 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:1352010 6480464 2 more ... CTD PMID:26988655 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO RGD:1352010 6480464 2 more ... CTD PMID:31675489 2,2',5,5'-tetrachlorobiphenyl increases expression ISO RGD:1352010 6480464 2 more ... CTD PMID:21703328 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO RGD:70501 6480464 [2 more ... CTD PMID:25510870 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1352010 6480464 Tetrachlorodibenzodioxin results in increased expression of CDK2 mRNA CTD PMID:21296121 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:70501 6480464 Tetrachlorodibenzodioxin results in decreased expression of CDK2 mRNA CTD PMID:21041162 2,3,7,8-tetrachlorodibenzodioxine decreases activity ISO RGD:70501 6480464 Tetrachlorodibenzodioxin results in decreased activity of CDK2 protein CTD PMID:16636136 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:70501 6480464 Tetrachlorodibenzodioxin results in increased expression of CDK2 protein CTD PMID:10398686 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:70501 6480464 Tetrachlorodibenzodioxin affects the expression of CDK2 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:70501 6480464 [Tetrachlorodibenzodioxin promotes the reaction [1 more ... CTD PMID:16636136 , PMID:20637255 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1352010 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased activity of CDK2 protein], Tetrachlorodibenzodioxin promotes the reaction [Estradiol inhibits the reaction [CDK2 protein binds to CDKN1A protein]] CTD PMID:9705214 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Gonadotropins more ... CTD PMID:12387751 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of CDK2 mRNA CTD PMID:20724799 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1352010 6480464 Tetrachlorodibenzodioxin results in decreased expression of CDK2 mRNA CTD PMID:21802500 2,4,6-tribromophenol decreases expression ISO RGD:1352010 6480464 2 more ... CTD PMID:31675489 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of CDK2 mRNA CTD PMID:21346803 2-acetamidofluorene decreases activity EXP 6480464 2-Acetylaminofluorene results in decreased activity of CDK2 protein CTD PMID:15158336 2-acetamidofluorene multiple interactions EXP 6480464 2-Acetylaminofluorene inhibits the reaction [CDK2 protein binds to CCNE1 protein], 2-Acetylaminofluorene results in decreased localization of and results in decreased phosphorylation of and results in decreased activity of CDK2 protein CTD PMID:10708481 2-methoxy-17beta-estradiol decreases expression ISO RGD:1352010 6480464 2-Methoxyestradiol results in decreased expression of CDK2 protein CTD PMID:23967052 2-trans,6-trans,10-trans-geranylgeranyl diphosphate multiple interactions EXP 6480464 geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CDK2 protein] CTD PMID:26577051 3,3',4,4',5-pentachlorobiphenyl affects expression ISO RGD:1352010 6480464 3 more ... CTD PMID:21703328 3,3',5,5'-tetrabromobisphenol A decreases expression ISO RGD:1352010 6480464 tetrabromobisphenol A results in decreased expression of CDK2 protein CTD PMID:31675489 3,3'-diindolylmethane multiple interactions ISO RGD:1352010 6480464 3, 3'-diindolylmethane promotes the reaction [CDK2 protein binds to CDKN1A protein] CTD PMID:15611077 3,3'-diindolylmethane decreases activity ISO RGD:1352010 6480464 3, 3'-diindolylmethane results in decreased activity of CDK2 protein CTD PMID:15611077 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:70501 6480464 14-deoxy-11 more ... CTD PMID:24646949 more ... 3-methylcholanthrene decreases expression ISO RGD:1352010 6480464 Methylcholanthrene results in decreased expression of CDK2 protein CTD PMID:18022818 3-methylcholanthrene multiple interactions EXP 6480464 alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CDK2 promoter]] more ... CTD PMID:29094188 3-methylcholanthrene increases expression EXP 6480464 Methylcholanthrene results in increased expression of CDK2 mRNA CTD PMID:29094188 3-methylcholanthrene decreases methylation EXP 6480464 Methylcholanthrene results in decreased methylation of CDK2 promoter CTD PMID:29094188 3-methylcholanthrene increases acetylation EXP 6480464 Methylcholanthrene results in increased acetylation of CDK2 promoter CTD PMID:29094188 4-(ethoxymethylene)-2-phenyloxazol-5-one increases expression ISO RGD:70501 6480464 Oxazolone results in increased expression of CDK2 mRNA CTD PMID:21404309 4-hydroxynon-2-enal multiple interactions ISO RGD:1352010 6480464 4-hydroxy-2-nonenal binds to and results in increased alkylation of and results in decreased activity of CDK2 protein CTD PMID:26910110 5-aza-2'-deoxycytidine increases expression ISO RGD:70501 6480464 Decitabine results in increased expression of CDK2 mRNA CTD PMID:27915011 5-azacytidine decreases expression ISO RGD:1352010 6480464 Azacitidine analog results in decreased expression of CDK2 protein CTD PMID:18324645 5-fluorouracil affects response to substance ISO RGD:1352010 6480464 CDK2 protein affects the susceptibility to Fluorouracil, CDK2 protein modified form affects the susceptibility to Fluorouracil CTD PMID:15548681 , PMID:18383818 5-fluorouracil multiple interactions ISO RGD:1352010 6480464 [Leucovorin co-treated with Fluorouracil] results in increased expression of CDK2 mRNA CTD PMID:15342418 5-fluorouracil increases expression ISO RGD:1352010 6480464 Fluorouracil results in increased expression of CDK2 mRNA CTD PMID:16557594 5-formyltetrahydrofolic acid multiple interactions ISO RGD:1352010 6480464 [Leucovorin co-treated with Fluorouracil] results in increased expression of CDK2 mRNA CTD PMID:15342418 5-methoxypsoralen decreases expression ISO RGD:1352010 6480464 5-Methoxypsoralen results in decreased expression of CDK2 protein CTD PMID:30576070 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of CDK2 mRNA CTD PMID:24780913 8-Br-cAMP decreases expression ISO RGD:1352010 6480464 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CDK2 mRNA CTD PMID:22079614 acetylsalicylic acid decreases expression ISO RGD:1352010 6480464 Aspirin results in decreased expression of CDK2 mRNA, Aspirin results in decreased expression of CDK2 protein CTD PMID:19908241 , PMID:20457246 acetylsalicylic acid multiple interactions ISO RGD:1352010 6480464 troglitazone promotes the reaction [Aspirin results in decreased expression of CDK2 protein] CTD PMID:19908241 acrylamide increases expression ISO RGD:1352010 6480464 Acrylamide results in increased expression of CDK2 protein CTD PMID:20734998 acrylamide decreases expression ISO RGD:1352010 6480464 Acrylamide results in decreased expression of CDK2 mRNA CTD PMID:32763439 acrylamide multiple interactions ISO RGD:70501 6480464 [Acrylamide co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CDK2 protein CTD PMID:30409764 acrylamide decreases expression ISO RGD:70501 6480464 Acrylamide analog results in decreased expression of CDK2 protein CTD PMID:17317719 acteoside multiple interactions ISO RGD:1352010 6480464 acteoside results in decreased expression of and results in decreased activity of CDK2 protein CTD PMID:17634406 afimoxifene multiple interactions ISO RGD:1352010 6480464 [afimoxifene co-treated with lapatinib] promotes the reaction [CDKN1B protein binds to and results in decreased activity of [CCNE1 protein binds to CDK2 protein]], afimoxifene promotes the reaction [CDKN1B protein binds to and results in decreased activity of [CCNE1 protein binds to CDK2 protein]] CTD PMID:15665275 albuterol increases expression ISO RGD:1352010 6480464 Albuterol results in increased expression of CDK2 protein CTD PMID:18362475 all-trans-retinoic acid multiple interactions ISO RGD:1352010 6480464 [Tretinoin co-treated with caffeic acid phenethyl ester] inhibits the reaction [CDK2 protein binds to CCNE1 protein] more ... CTD PMID:12012012 more ... all-trans-retinoic acid decreases degradation ISO RGD:1352010 6480464 Tretinoin results in decreased degradation of CDK2 protein CTD PMID:20935519 all-trans-retinoic acid decreases expression EXP 6480464 Tretinoin results in decreased expression of CDK2 protein CTD PMID:11675954 all-trans-retinoic acid multiple interactions EXP 6480464 Tretinoin inhibits the reaction [FGF2 protein results in increased expression of CDK2 mRNA] CTD PMID:11675954 all-trans-retinoic acid decreases expression ISO RGD:1352010 6480464 Tretinoin results in decreased expression of CDK2 protein CTD PMID:16517207 , PMID:17960384 alpha-naphthoflavone multiple interactions EXP 6480464 alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CDK2 promoter]] more ... CTD PMID:29094188 alpha-naphthoflavone decreases methylation EXP 6480464 alpha-naphthoflavone results in decreased methylation of CDK2 promoter CTD PMID:29094188 alpha-Zearalanol decreases expression ISO RGD:70501 6480464 Zeranol results in decreased expression of CDK2 protein CTD PMID:24120472 alsterpaullone decreases activity ISO RGD:1352010 6480464 alsterpaullone results in decreased activity of CDK2 protein CTD PMID:12534346 alvocidib decreases expression ISO RGD:1352010 6480464 alvocidib results in decreased expression of CDK2 protein modified form CTD PMID:16905211 alvocidib decreases activity ISO RGD:1352010 6480464 alvocidib results in decreased activity of CDK2 protein CTD PMID:12517783 , PMID:9802881 alvocidib multiple interactions ISO RGD:1352010 6480464 alvocidib binds to and results in decreased activity of CDK2 protein, alvocidib inhibits the reaction [Paclitaxel results in increased activity of CDK2 protein] CTD PMID:10430095 , PMID:24102143 amlodipine decreases activity ISO RGD:1352010 6480464 Amlodipine results in decreased activity of CDK2 protein CTD PMID:17217918 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of CDK2 mRNA CTD PMID:16483693 andrographolide decreases expression ISO RGD:1352010 6480464 andrographolide results in decreased expression of CDK2 protein CTD PMID:18619950 andrographolide multiple interactions ISO RGD:70501 6480464 andrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CDK2 protein] CTD PMID:27475717 andrographolide multiple interactions ISO RGD:1352010 6480464 andrographolide inhibits the reaction [CCNA2 protein binds to CDK2 protein] CTD PMID:18619950 aniline increases expression EXP 6480464 aniline results in increased expression of CDK2 protein CTD PMID:21070798 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:1352010 6480464 pyrazolanthrone inhibits the reaction [naphtho(1 more ... CTD PMID:19747539 anthra[1,9-cd]pyrazol-6(2H)-one decreases activity ISO RGD:1352010 6480464 pyrazolanthrone results in decreased activity of CDK2 protein CTD PMID:12534346 anthracene increases expression ISO RGD:1352010 6480464 anthracene results in increased expression of CDK2 protein CTD PMID:28803881 anthracene multiple interactions ISO RGD:1352010 6480464 [naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] results in increased expression of CDK2 protein CTD PMID:28803881 antirheumatic drug decreases expression ISO RGD:1352010 6480464 Antirheumatic Agents results in decreased expression of CDK2 mRNA CTD PMID:17696278 antroquinonol multiple interactions ISO RGD:1352010 6480464 antroquinonol results in decreased expression of and results in decreased localization of CDK2 protein CTD PMID:19723512 arsane multiple interactions ISO RGD:1352010 6480464 [silybin co-treated with Arsenic] results in decreased expression of CDK2 protein CTD PMID:25868784 arsane affects methylation ISO RGD:1352010 6480464 Arsenic affects the methylation of CDK2 gene CTD PMID:25304211 arsenic atom multiple interactions ISO RGD:1352010 6480464 [silybin co-treated with Arsenic] results in decreased expression of CDK2 protein CTD PMID:25868784 arsenic atom affects methylation ISO RGD:1352010 6480464 Arsenic affects the methylation of CDK2 gene CTD PMID:25304211 arsenous acid decreases expression ISO RGD:1352010 6480464 Arsenic Trioxide results in decreased expression of CDK2 mRNA CTD PMID:20458559 arsenous acid multiple interactions ISO RGD:1352010 6480464 [ruxolitinib co-treated with Arsenic Trioxide] results in decreased expression of CDK2 mRNA more ... CTD PMID:12480548 more ... Aspidin increases expression ISO RGD:1352010 6480464 aspidin BB results in increased expression of CDK2 protein CTD PMID:23628508 benzene increases activity ISO RGD:1352010 6480464 Benzene results in increased activity of CDK2 protein CTD PMID:9118908 benzene increases activity EXP 6480464 Benzene results in increased activity of CDK2 protein CTD PMID:9118908 benzo[a]pyrene increases expression ISO RGD:1352010 6480464 Benzo(a)pyrene results in increased expression of CDK2 mRNA CTD PMID:19027820 more ... benzo[a]pyrene decreases expression ISO RGD:70501 6480464 Benzo(a)pyrene results in decreased expression of CDK2 mRNA, Benzo(a)pyrene results in decreased expression of CDK2 protein CTD PMID:35038060 benzo[a]pyrene affects methylation ISO RGD:1352010 6480464 Benzo(a)pyrene affects the methylation of CDK2 3' UTR, Benzo(a)pyrene affects the methylation of CDK2 promoter CTD PMID:27901495 benzo[a]pyrene increases expression ISO RGD:70501 6480464 Benzo(a)pyrene results in increased expression of CDK2 mRNA CTD PMID:22342234 benzo[a]pyrene multiple interactions EXP 6480464 AHR affects the reaction [Benzo(a)pyrene results in increased activity of [CCNA2 protein binds to CDK2 protein]], Benzo(a)pyrene results in increased activity of [CCNA2 protein binds to CDK2 protein] CTD PMID:17141280 benzo[a]pyrene decreases expression ISO RGD:1352010 6480464 Benzo(a)pyrene results in decreased expression of CDK2 mRNA CTD PMID:21632981 , PMID:21802500 benzo[a]pyrene diol epoxide I increases expression ISO RGD:1352010 6480464 7 more ... CTD PMID:19150397 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:1352010 6480464 7 more ... CTD PMID:35038060 benzo[b]fluoranthene multiple interactions EXP 6480464 AHR affects the reaction [benzo(b)fluoranthene results in increased activity of [CCNA2 protein binds to CDK2 protein]], benzo(b)fluoranthene results in increased activity of [CCNA2 protein binds to CDK2 protein] CTD PMID:17141280 berberine decreases expression ISO RGD:1352010 6480464 Berberine results in decreased expression of CDK2 protein CTD PMID:16505103 beta-ionone decreases expression ISO RGD:1352010 6480464 beta-ionone results in decreased expression of CDK2 protein CTD PMID:15450939 biotin increases expression ISO RGD:70501 6480464 Biotin results in increased expression of CDK2 mRNA CTD PMID:34699867 biphenyl-4-amine decreases expression ISO RGD:1352010 6480464 4-biphenylamine results in decreased expression of CDK2 mRNA CTD PMID:32905825 biphenyl-4-amine multiple interactions ISO RGD:1352010 6480464 TP53 protein inhibits the reaction [4-biphenylamine results in decreased expression of CDK2 mRNA] CTD PMID:32905825 bis(2-chloroethyl) sulfide decreases expression ISO RGD:1352010 6480464 Mustard Gas results in decreased expression of CDK2 mRNA CTD PMID:33491125 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of CDK2 protein CTD PMID:22985736 bisphenol A decreases expression ISO RGD:70501 6480464 bisphenol A results in decreased expression of CDK2 mRNA CTD PMID:23798566 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of CDK2 mRNA CTD PMID:30816183 , PMID:34947998 bisphenol A affects expression ISO RGD:1352010 6480464 bisphenol A affects the expression of CDK2 mRNA CTD PMID:30903817 bisphenol A decreases phosphorylation ISO RGD:1352010 6480464 bisphenol A results in decreased phosphorylation of CDK2 protein CTD PMID:29275510 bisphenol A decreases expression ISO RGD:1352010 6480464 bisphenol A results in decreased expression of CDK2 mRNA CTD PMID:29275510 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of CDK2 mRNA CTD PMID:25181051 bisphenol A increases expression ISO RGD:1352010 6480464 bisphenol A results in increased expression of CDK2 mRNA, bisphenol A results in increased expression of CDK2 protein CTD PMID:16474171 more ... bisphenol A multiple interactions ISO RGD:1352010 6480464 [bisphenol A co-treated with resveratrol] results in decreased expression of CDK2 mRNA, Curcumin inhibits the reaction [bisphenol A results in increased expression of CDK2 protein] CTD PMID:22552626 , PMID:23222814 Bisphenol B increases expression EXP 6480464 bisphenol B results in increased expression of CDK2 mRNA, bisphenol B results in increased expression of CDK2 protein CTD PMID:33940105 bisphenol F multiple interactions ISO RGD:1352010 6480464 [bisphenol F co-treated with Fulvestrant] results in increased methylation of CDK2 gene CTD PMID:31601247 bohemine decreases activity ISO RGD:70501 6480464 bohemine results in decreased activity of CDK2 protein CTD PMID:15026556 bortezomib multiple interactions ISO RGD:1352010 6480464 Bortezomib inhibits the reaction [docetaxel results in increased activity of CDK2 protein] CTD PMID:14749476 bortezomib decreases activity ISO RGD:1352010 6480464 Bortezomib results in decreased activity of CDK2 protein CTD PMID:14749476 bosutinib decreases activity ISO RGD:70501 6480464 bosutinib results in decreased activity of CDK2 protein CTD PMID:17129604 bosutinib decreases expression ISO RGD:70501 6480464 bosutinib results in decreased expression of CDK2 protein CTD PMID:17129604 BQ 123 multiple interactions ISO RGD:1352010 6480464 cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [VEGFC protein results in increased expression of CDK2 protein] CTD PMID:24184161 brassinolide decreases expression ISO RGD:1352010 6480464 brassinolide results in decreased expression of CDK2 protein CTD PMID:20833159 busulfan decreases expression ISO RGD:70501 6480464 Busulfan results in decreased expression of CDK2 mRNA CTD PMID:15388331 Butylparaben increases expression ISO RGD:1352010 6480464 butylparaben results in increased expression of CDK2 mRNA CTD PMID:24481588 cadmium dichloride decreases methylation EXP 6480464 Cadmium Chloride results in decreased methylation of CDK2 promoter CTD PMID:22457795 cadmium dichloride multiple interactions ISO RGD:1352010 6480464 [2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3 more ... CTD PMID:26385184 cadmium dichloride increases expression ISO RGD:1352010 6480464 Cadmium Chloride results in increased expression of CDK2 mRNA, Cadmium Chloride results in increased expression of CDK2 protein CTD PMID:20219890 , PMID:26385184 caffeine decreases activity ISO RGD:1352010 6480464 Caffeine results in decreased activity of CDK2 protein CTD PMID:11835680 caffeine increases phosphorylation ISO RGD:1352010 6480464 Caffeine results in increased phosphorylation of CDK2 protein CTD PMID:35688186 calciol multiple interactions ISO RGD:1352010 6480464 Cholecalciferol promotes the reaction [CDKN1B protein binds to CDK2 protein] CTD PMID:12907249 calciol decreases phosphorylation ISO RGD:1352010 6480464 Cholecalciferol results in decreased phosphorylation of CDK2 protein CTD PMID:12907249 calciol decreases activity ISO RGD:1352010 6480464 Cholecalciferol results in decreased activity of CDK2 protein CTD PMID:12907249 calcitriol decreases activity ISO RGD:1352010 6480464 Calcitriol results in decreased activity of CDK2 protein CTD PMID:12954644 calcitriol multiple interactions ISO RGD:1352010 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of CDK2 mRNA CTD PMID:21592394 calcitriol decreases localization ISO RGD:1352010 6480464 Calcitriol results in decreased localization of CDK2 protein CTD PMID:12954644 calcitriol decreases expression ISO RGD:1352010 6480464 Calcitriol results in decreased expression of CDK2 mRNA CTD PMID:21592394 calix[6]arene decreases expression ISO RGD:1352010 6480464 calix(6)arene results in decreased expression of CDK2 protein CTD PMID:23872419 camptothecin multiple interactions ISO RGD:1352010 6480464 Camptothecin results in increased phosphorylation of and results in decreased activity of CDK2 protein CTD PMID:15141020 cannabidiol decreases expression ISO RGD:70501 6480464 Cannabidiol results in decreased expression of CDK2 protein CTD PMID:34871667 cannabidiol decreases expression ISO RGD:1352010 6480464 Cannabidiol results in decreased expression of CDK2 protein CTD PMID:31349651 , PMID:34871667 cannabidiol multiple interactions ISO RGD:1352010 6480464 [Oxygen co-treated with Ozone co-treated with Cannabidiol] results in decreased expression of CDK2 mRNA CTD PMID:32992648 capsaicin decreases expression ISO RGD:1352010 6480464 Capsaicin results in decreased expression of CDK2 protein CTD PMID:20646592 carbamate ester affects expression ISO RGD:70501 6480464 Carbamates affects the expression of CDK2 protein CTD PMID:21303328 carbamazepine affects expression ISO RGD:1352010 6480464 Carbamazepine affects the expression of CDK2 mRNA CTD PMID:24752500 carbon nanotube decreases expression ISO RGD:1352010 6480464 Nanotubes, Carbon results in decreased expression of CDK2 mRNA CTD PMID:15585362 carbon nanotube increases expression ISO RGD:70501 6480464 Nanotubes, Carbon results in increased expression of CDK2 mRNA CTD PMID:25554681 Cardanol decreases expression ISO RGD:1352010 6480464 cardanol results in decreased expression of CDK2 mRNA CTD PMID:26694491 casticin increases expression ISO RGD:1352010 6480464 casticin results in increased expression of CDK2 protein CTD PMID:29098808 celastrol decreases expression ISO RGD:1352010 6480464 celastrol results in decreased expression of CDK2 mRNA CTD PMID:17010675 celecoxib decreases expression ISO RGD:1352010 6480464 Celecoxib results in decreased expression of CDK2 protein, Celecoxib results in decreased expression of CDK2 protein modified form CTD PMID:16136956 , PMID:19428934 choline multiple interactions ISO RGD:70501 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CDK2 gene CTD PMID:20938992 chromium(6+) multiple interactions EXP 6480464 Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CDK2 protein] CTD PMID:21621607 chromium(6+) multiple interactions ISO RGD:70501 6480464 [sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in decreased expression of CDK2 protein, Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in decreased expression of CDK2 protein] CTD PMID:35643323 chromium(6+) decreases expression ISO RGD:1352010 6480464 chromium hexavalent ion results in decreased expression of CDK2 protein CTD PMID:22886373 chromium(6+) decreases expression EXP 6480464 chromium hexavalent ion results in decreased expression of CDK2 protein CTD PMID:21621607 Cinobufagin decreases expression ISO RGD:1352010 6480464 cinobufagin results in decreased expression of CDK2 mRNA, cinobufagin results in decreased expression of CDK2 protein CTD PMID:21215801 Cinobufagin multiple interactions ISO RGD:1352010 6480464 cinobufagin results in decreased expression of and results in decreased phosphorylation of CDK2 protein CTD PMID:34619160 ciprofloxacin decreases phosphorylation ISO RGD:1352010 6480464 Ciprofloxacin results in decreased phosphorylation of CDK2 protein CTD PMID:10741713 Cirsimarin decreases expression ISO RGD:1352010 6480464 cirsimarin results in decreased expression of CDK2 mRNA CTD PMID:35710092 cis-caffeic acid multiple interactions ISO RGD:1352010 6480464 caffeic acid promotes the reaction [Thapsigargin results in increased expression of CDK2 mRNA] CTD PMID:19442820 cisplatin multiple interactions ISO RGD:1352010 6480464 [Cisplatin co-treated with Quercetin] results in increased expression of CDK2 mRNA more ... CTD PMID:12012012 more ... cisplatin increases expression ISO RGD:1352010 6480464 Cisplatin results in increased expression of CDK2 mRNA, Cisplatin results in increased expression of CDK2 protein CTD PMID:27594783 , PMID:32562082 cisplatin multiple interactions ISO RGD:70501 6480464 Cisplatin promotes the reaction [CDK2 protein binds to and results in increased phosphorylation of CDKN1A protein] CTD PMID:21325496 cisplatin increases phosphorylation ISO RGD:1352010 6480464 Cisplatin results in increased phosphorylation of CDK2 protein CTD PMID:21592546 citric acid multiple interactions ISO RGD:1352010 6480464 [Silver analog co-treated with Citric Acid] affects the expression of CDK2 mRNA CTD PMID:27021274 clobenpropit multiple interactions ISO RGD:1352010 6480464 [HRH4 protein results in increased susceptibility to clobenpropit] which results in decreased expression of CDK2 protein CTD PMID:22363581 clofibrate multiple interactions ISO RGD:70501 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of CDK2 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CDK2 mRNA] CTD PMID:17585979 cobalt dichloride decreases expression ISO RGD:1352010 6480464 cobaltous chloride results in decreased expression of CDK2 mRNA CTD PMID:19320972 copper atom multiple interactions ISO RGD:1352010 6480464 [Chelating Agents binds to Copper] which results in decreased expression of CDK2 mRNA, [NSC 689534 binds to Copper] which results in decreased expression of CDK2 mRNA CTD PMID:20971185 , PMID:30911355 copper(0) multiple interactions ISO RGD:1352010 6480464 [Chelating Agents binds to Copper] which results in decreased expression of CDK2 mRNA, [NSC 689534 binds to Copper] which results in decreased expression of CDK2 mRNA CTD PMID:20971185 , PMID:30911355 coptisine decreases expression ISO RGD:1352010 6480464 coptisine analog results in decreased expression of CDK2 protein CTD PMID:30472432 corticosterone multiple interactions EXP 6480464 Corticosterone promotes the reaction [CDKN1A protein binds to CDK2 protein] CTD PMID:12807724 corticosterone decreases activity EXP 6480464 Corticosterone results in decreased activity of CDK2 protein CTD PMID:12807724 corticosterone decreases expression EXP 6480464 Corticosterone results in decreased expression of CDK2 protein CTD PMID:12807724 coumarin decreases expression ISO RGD:1352010 6480464 coumarin analog results in decreased expression of CDK2 mRNA CTD PMID:32578917 coumarin increases phosphorylation ISO RGD:1352010 6480464 coumarin results in increased phosphorylation of CDK2 protein CTD PMID:35688186 coumestrol decreases expression ISO RGD:1352010 6480464 Coumestrol results in decreased expression of CDK2 protein CTD PMID:28986287 curcumin multiple interactions ISO RGD:1352010 6480464 Curcumin inhibits the reaction [bisphenol A results in increased expression of CDK2 protein] CTD PMID:23222814 curcumin decreases expression ISO RGD:70501 6480464 Curcumin results in decreased expression of CDK2 protein CTD PMID:19501152 curcumin decreases expression ISO RGD:1352010 6480464 Curcumin analog results in decreased expression of CDK2 mRNA, Curcumin results in decreased expression of CDK2 protein CTD PMID:23222814 , PMID:26409325 cycloheximide multiple interactions ISO RGD:1352010 6480464 Cycloheximide inhibits the reaction [Dexamethasone results in decreased expression of CDK2 mRNA] CTD PMID:12800980 cyclophosphamide decreases expression ISO RGD:70501 6480464 Cyclophosphamide results in decreased expression of CDK2 mRNA CTD PMID:21041162 cyclosporin A decreases expression ISO RGD:1352010 6480464 Cyclosporine results in decreased expression of CDK2 mRNA CTD PMID:20106945 more ... daidzein multiple interactions ISO RGD:1352010 6480464 daidzein promotes the reaction [CDKN1A protein binds to CDK2 protein] CTD PMID:11322924 daidzein decreases activity ISO RGD:1352010 6480464 daidzein results in decreased activity of CDK2 protein CTD PMID:11322924 DDT increases activity ISO RGD:1352010 6480464 DDT results in increased activity of CDK2 protein CTD PMID:8927716 , PMID:9168006 DDT multiple interactions ISO RGD:1352010 6480464 DDT results in increased phosphorylation of and results in increased activity of CDK2 protein, fulvestrant inhibits the reaction [DDT results in increased phosphorylation of and results in increased activity of CDK2 protein] CTD PMID:9049186 deferasirox decreases activity ISO RGD:1352010 6480464 deferasirox results in decreased activity of CDK2 protein CTD PMID:17631934 desferrioxamine B decreases activity ISO RGD:1352010 6480464 Deferoxamine results in decreased activity of CDK2 protein CTD PMID:17631934 desferrioxamine B decreases expression ISO RGD:1352010 6480464 Deferoxamine results in decreased expression of CDK2 protein CTD PMID:11468187 dexamethasone multiple interactions ISO RGD:1352010 6480464 Cycloheximide inhibits the reaction [Dexamethasone results in decreased expression of CDK2 mRNA], Dexamethasone inhibits the reaction [CDK2 protein binds to CDKN1A protein] CTD PMID:12800980 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of CDK2 mRNA CTD PMID:29111458 dexamethasone increases expression ISO RGD:1352010 6480464 Dexamethasone results in increased expression of CDK2 mRNA CTD PMID:23137833 dexamethasone decreases expression ISO RGD:70501 6480464 Dexamethasone results in decreased expression of CDK2 mRNA CTD PMID:21041162 dexamethasone multiple interactions ISO RGD:70501 6480464 14-deoxy-11 more ... CTD PMID:24646949 more ... dexamethasone multiple interactions EXP 6480464 Dexamethasone inhibits the reaction [CDK2 protein results in increased phosphorylation of RB1 protein] CTD PMID:9442036 dexamethasone decreases expression ISO RGD:1352010 6480464 Dexamethasone results in decreased expression of CDK2 mRNA more ... CTD PMID:12800980 , PMID:19428934 dexamethasone decreases activity ISO RGD:1352010 6480464 Dexamethasone results in decreased activity of CDK2 protein CTD PMID:12800980 diarsenic trioxide multiple interactions ISO RGD:1352010 6480464 [ruxolitinib co-treated with Arsenic Trioxide] results in decreased expression of CDK2 mRNA more ... CTD PMID:12480548 more ... diarsenic trioxide decreases expression ISO RGD:1352010 6480464 Arsenic Trioxide results in decreased expression of CDK2 mRNA CTD PMID:20458559 diclofenac affects expression ISO RGD:1352010 6480464 Diclofenac affects the expression of CDK2 mRNA CTD PMID:24752500 dieldrin affects expression EXP 6480464 Dieldrin affects the expression of CDK2 mRNA CTD PMID:22546817 diethyl sulfate affects phosphorylation ISO RGD:1352010 6480464 diethyl sulfate affects the phosphorylation of CDK2 protein CTD PMID:23887207 diethylstilbestrol decreases expression ISO RGD:70501 6480464 Diethylstilbestrol results in decreased expression of CDK2 mRNA CTD PMID:21041162 dinophysistoxin 2 decreases expression ISO RGD:1352010 6480464 dinophysistoxin 2 results in decreased expression of CDK2 mRNA CTD PMID:21512803 dioscin decreases expression ISO RGD:1352010 6480464 dioscin results in decreased expression of CDK2 mRNA, dioscin results in decreased expression of CDK2 protein CTD PMID:33359023 dioxygen multiple interactions ISO RGD:1352010 6480464 [Oxygen co-treated with Ozone co-treated with Cannabidiol] results in decreased expression of CDK2 mRNA, [Oxygen co-treated with Ozone] results in decreased expression of CDK2 mRNA CTD PMID:32992648 dorsomorphin multiple interactions ISO RGD:70501 6480464 dorsomorphin inhibits the reaction [14-deoxy-11, 12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of CDK2 protein]] CTD PMID:30248417 doxorubicin increases response to substance ISO RGD:1352010 6480464 CDK2 protein results in increased susceptibility to Doxorubicin CTD PMID:15823547 doxorubicin increases phosphorylation ISO RGD:70501 6480464 Doxorubicin results in increased phosphorylation of CDK2 protein CTD PMID:15861398 doxorubicin multiple interactions ISO RGD:70501 6480464 [Zoledronic Acid co-treated with Doxorubicin] results in decreased expression of CDK2 protein more ... CTD PMID:15861398 more ... doxorubicin decreases activity ISO RGD:1352010 6480464 Doxorubicin results in decreased activity of CDK2 protein CTD PMID:25124555 doxorubicin affects response to substance ISO RGD:1352010 6480464 CDK2 protein affects the susceptibility to Doxorubicin CTD PMID:16036217 , PMID:16217747 doxorubicin multiple interactions EXP 6480464 [Roscovitine results in decreased activity of CDK2 protein] inhibits the reaction [TAF1 protein results in decreased susceptibility to Doxorubicin] more ... CTD PMID:15124910 , PMID:32075913 doxorubicin increases activity EXP 6480464 Doxorubicin results in increased activity of CDK2 protein CTD PMID:15124910 doxorubicin decreases response to substance EXP 6480464 CDK2 protein results in decreased susceptibility to Doxorubicin CTD PMID:15124910 doxorubicin multiple interactions ISO RGD:1352010 6480464 [Doxorubicin co-treated with TNF protein] results in increased activity of CDK2 protein more ... CTD PMID:15823547 , PMID:25124555 doxorubicin affects activity ISO RGD:1352010 6480464 Doxorubicin affects the activity of CDK2 protein CTD PMID:16036217 dronedarone decreases expression ISO RGD:1352010 6480464 dronedarone results in decreased expression of CDK2 protein CTD PMID:29616291 Echimidine multiple interactions ISO RGD:1352010 6480464 [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of CDK2 mRNA CTD PMID:33884520 elemental selenium decreases expression ISO RGD:1352010 6480464 Selenium deficiency results in decreased expression of CDK2 mRNA CTD PMID:11925459 embelin decreases expression ISO RGD:1352010 6480464 embelin results in decreased expression of CDK2 protein CTD PMID:24694877 erythrosin B increases activity ISO RGD:1352010 6480464 Erythrosine results in increased activity of CDK2 protein CTD PMID:8927716 , PMID:9168006 esculetin decreases expression EXP 6480464 esculetin results in decreased expression of CDK2 protein CTD PMID:21600278 esculetin multiple interactions EXP 6480464 esculetin promotes the reaction [CDKN1A protein binds to CDK2 protein], SB 203580 inhibits the reaction [esculetin results in decreased expression of CDK2 protein] CTD PMID:21600278 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of CDK2 mRNA CTD PMID:32497709 , PMID:34547370 ethyl trans-caffeate affects expression ISO RGD:1352010 6480464 ethyl caffeate affects the expression of CDK2 protein CTD PMID:24892518 etoposide multiple interactions ISO RGD:1352010 6480464 BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of CDK2 protein], CDK2 affects the reaction [Etoposide results in increased phosphorylation of TPI1 protein] CTD PMID:16417649 , PMID:20149834 etoposide increases expression ISO RGD:1352010 6480464 Etoposide results in increased expression of CDK2 protein CTD PMID:16417649 etoposide affects response to substance ISO RGD:1352010 6480464 CDK2 protein affects the susceptibility to Etoposide CTD PMID:16217747 farnesol decreases expression ISO RGD:1352010 6480464 Farnesol results in decreased expression of CDK2 protein CTD PMID:17138864 farnesol multiple interactions ISO RGD:1352010 6480464 Farnesol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein], Farnesol promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein] CTD PMID:17138864 fenthion decreases expression ISO RGD:70501 6480464 Fenthion results in decreased expression of CDK2 mRNA CTD PMID:34813904 fenvalerate increases expression ISO RGD:1352010 6480464 fenvalerate results in increased expression of CDK2 mRNA CTD PMID:22850687 fenvalerate affects binding ISO RGD:1352010 6480464 fenvalerate binds to CDK2 protein CTD PMID:32278787 fenvalerate multiple interactions ISO RGD:1352010 6480464 CDKN1B protein inhibits the reaction [fenvalerate results in increased expression of CDK2 mRNA] CTD PMID:22850687 fipronil decreases expression EXP 6480464 fipronil results in decreased expression of CDK2 mRNA CTD PMID:34044035 fisetin decreases expression ISO RGD:1352010 6480464 fisetin results in decreased expression of CDK2 protein CTD PMID:28181380 fluvalinate affects binding ISO RGD:1352010 6480464 fluvalinate binds to CDK2 protein CTD PMID:32278787 folic acid multiple interactions ISO RGD:70501 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CDK2 gene CTD PMID:20938992 folic acid decreases expression ISO RGD:1352010 6480464 Folic Acid results in decreased expression of CDK2 protein CTD PMID:26056802 fraxetin decreases expression ISO RGD:1352010 125097526 Fraxetin decreases expression of CDK2 protein in colorectum RGD fulvestrant increases expression ISO RGD:1352010 6480464 fulvestrant results in increased expression of CDK2 mRNA CTD PMID:20215421 fulvestrant multiple interactions ISO RGD:1352010 6480464 [bisphenol F co-treated with Fulvestrant] results in increased methylation of CDK2 gene more ... CTD PMID:31601247 , PMID:9049186 furan increases expression EXP 6480464 furan results in increased expression of CDK2 mRNA CTD PMID:22079235 gamma-tocopherol decreases expression ISO RGD:1352010 6480464 Tocopherols results in decreased expression of CDK2 protein CTD PMID:12504091 gedunin decreases expression ISO RGD:1352010 6480464 gedunin results in decreased expression of CDK2 mRNA CTD PMID:17010675 genistein increases expression ISO RGD:1352010 6480464 Genistein results in increased expression of CDK2 mRNA CTD PMID:16474171 genistein decreases expression ISO RGD:70501 6480464 Genistein results in decreased expression of CDK2 mRNA CTD PMID:21048042 geraniol decreases expression ISO RGD:1352010 6480464 geraniol results in decreased expression of CDK2 mRNA, geraniol results in decreased expression of CDK2 protein CTD PMID:15450939 more ... geraniol multiple interactions ISO RGD:1352010 6480464 geraniol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein], geraniol promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein] CTD PMID:17138864 ginsenoside Rg1 multiple interactions ISO RGD:1352010 6480464 ginsenoside Rg1 affects the reaction [tert-Butylhydroperoxide affects the expression of CDK2 protein] CTD PMID:15606011 glutathione multiple interactions ISO RGD:1352010 6480464 Glutathione inhibits the reaction [rubimaillin results in decreased expression of CDK2 protein] CTD PMID:35007525 glyphosate increases expression ISO RGD:1352010 6480464 glyphosate results in increased expression of CDK2 protein CTD PMID:24073338 glyphosate decreases expression ISO RGD:1352010 6480464 glyphosate results in decreased expression of CDK2 mRNA CTD PMID:31295307 GW 3965 decreases expression ISO RGD:1352010 6480464 GW 3965 results in decreased expression of CDK2 mRNA CTD PMID:31437187 GW 4064 increases expression ISO RGD:1352010 6480464 GW 4064 results in increased expression of CDK2 mRNA CTD PMID:31437187 hesperetin decreases expression ISO RGD:1352010 6480464 hesperetin results in decreased expression of CDK2 CTD PMID:17927510 hesperidin multiple interactions EXP 6480464 Hesperidin inhibits the reaction [Diethylnitrosamine results in increased expression of CDK2 protein] CTD PMID:30779474 hexachlorobenzene multiple interactions ISO RGD:1352010 6480464 Hexachlorobenzene promotes the reaction [CDK2 protein binds to CCNE1 protein] CTD PMID:28215542 histamine multiple interactions ISO RGD:1352010 6480464 [HRH4 protein results in increased susceptibility to Histamine] which results in decreased expression of CDK2 protein CTD PMID:22363581 hydrogen peroxide decreases expression ISO RGD:1352010 6480464 Hydrogen Peroxide results in decreased expression of CDK2 mRNA, Hydrogen Peroxide results in decreased expression of CDK2 protein CTD PMID:12479875 hydrogen peroxide decreases activity ISO RGD:1352010 6480464 Hydrogen Peroxide results in decreased activity of CDK2 protein CTD PMID:12479875 indirubin decreases expression ISO RGD:70501 6480464 indirubin results in decreased expression of CDK2 protein CTD PMID:18344322 indirubin decreases activity ISO RGD:1352010 6480464 indirubin results in decreased activity of CDK2 protein CTD PMID:16115123 indirubin multiple interactions ISO RGD:1352010 6480464 indirubin inhibits the reaction [CDK2 protein results in increased phosphorylation of RB1 protein] CTD PMID:16115123 indirubin multiple interactions ISO RGD:70501 6480464 [tanshinone co-treated with indirubin] promotes the reaction [tetraarsenic tetrasulfide results in decreased expression of CDK2 protein], [tanshinone co-treated with tetraarsenic tetrasulfide] promotes the reaction [indirubin results in decreased expression of CDK2 protein] CTD PMID:18344322 indirubin-3'-monoxime decreases activity ISO RGD:1352010 6480464 indirubin-3'-monoxime results in decreased activity of CDK2 protein CTD PMID:12534346 indole-3-methanol affects localization ISO RGD:1352010 6480464 indole-3-carbinol affects the localization of CDK2 protein CTD PMID:15611077 indole-3-methanol decreases expression ISO RGD:1352010 6480464 indole-3-carbinol results in decreased expression of CDK2 CTD PMID:16082211 indole-3-methanol decreases activity ISO RGD:1352010 6480464 indole-3-carbinol analog results in decreased activity of CDK2 protein, indole-3-carbinol results in decreased activity of CDK2 protein CTD PMID:15611077 more ... indole-3-methanol multiple interactions ISO RGD:1352010 6480464 indole-3-carbinol affects the localization of [CDK2 protein binds to CCNE1 protein alternative form], indole-3-carbinol promotes the reaction [CDK2 protein binds to CCNE1 protein alternative form] CTD PMID:15611077 indometacin multiple interactions ISO RGD:1352010 6480464 Indomethacin promotes the reaction [CDKN1A protein results in decreased activity of CDK2 protein] CTD PMID:14566837 indometacin decreases expression ISO RGD:1352010 6480464 Indomethacin results in decreased expression of CDK2 protein, Indomethacin results in decreased expression of CDK2 protein modified form CTD PMID:15786552 , PMID:19428934 indometacin decreases activity ISO RGD:1352010 6480464 Indomethacin results in decreased activity of CDK2 protein CTD PMID:14566837 Isoangustone A multiple interactions ISO RGD:1352010 6480464 isoangustone A results in decreased expression of and results in decreased activity of CDK2 protein CTD PMID:21429724 Isoangustone A multiple interactions ISO RGD:70501 6480464 isoangustone A results in decreased expression of and results in decreased activity of CDK2 protein CTD PMID:21429724 ivermectin decreases expression ISO RGD:1352010 6480464 Ivermectin results in decreased expression of CDK2 protein CTD PMID:32959892 kainic acid increases expression EXP 6480464 Kainic Acid results in increased expression of CDK2 protein CTD PMID:12941380 kenpaullone decreases activity ISO RGD:1352010 6480464 kenpaullone results in decreased activity of CDK2 protein CTD PMID:12534346 L-ascorbic acid multiple interactions EXP 6480464 Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CDK2 protein] CTD PMID:21621607 L-methionine multiple interactions ISO RGD:70501 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CDK2 gene CTD PMID:20938992 lapatinib multiple interactions ISO RGD:1352010 6480464 [afimoxifene co-treated with lapatinib] promotes the reaction [CDKN1B protein binds to and results in decreased activity of [CCNE1 protein binds to CDK2 protein]], lapatinib promotes the reaction [CDKN1B protein binds to and results in decreased activity of [CCNE1 protein binds to CDK2 protein]] CTD PMID:15665275 Lasiocarpine multiple interactions ISO RGD:1352010 6480464 [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CDK2 mRNA CTD PMID:33884520 Licochalcone B decreases expression ISO RGD:1352010 6480464 licochalcone B results in decreased expression of CDK2 mRNA CTD PMID:24384411 lidocaine affects expression ISO RGD:70501 6480464 Lidocaine affects the expression of CDK2 mRNA CTD PMID:18931217 lidocaine increases expression EXP 6480464 Lidocaine results in increased expression of CDK2 mRNA CTD PMID:35283115 linuron decreases expression EXP 6480464 Linuron results in decreased expression of CDK2 mRNA CTD PMID:28705778 lovastatin decreases activity ISO RGD:1352010 6480464 Lovastatin results in decreased activity of CDK2 protein CTD PMID:10502407 luteolin decreases activity ISO RGD:1352010 6480464 Luteolin results in decreased activity of CDK2 protein CTD PMID:11322924 luteolin decreases expression ISO RGD:1352010 6480464 Luteolin results in decreased expression of CDK2 protein CTD PMID:22926442 luteolin 7-O-beta-D-glucoside decreases expression ISO RGD:1352010 6480464 luteolin-7-glucoside results in decreased expression of CDK2 protein CTD PMID:34165247 LY294002 multiple interactions ISO RGD:1352010 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Trichloroethylene results in increased expression of CDK2 protein] CTD PMID:34896440 malathion decreases expression ISO RGD:1352010 6480464 Malathion results in decreased expression of CDK2 protein CTD PMID:30769050 malathion increases expression ISO RGD:1352010 6480464 Malathion results in increased expression of CDK2 mRNA CTD PMID:32069766 maneb multiple interactions ISO RGD:70501 6480464 [Maneb co-treated with Paraquat] results in decreased expression of CDK2 mRNA more ... CTD PMID:23963992 mechlorethamine multiple interactions ISO RGD:1352010 6480464 Mechlorethamine results in decreased activity of [CCNA2 protein binds to CDK2 protein] more ... CTD PMID:8463339 mechlorethamine increases activity ISO RGD:1352010 6480464 Mechlorethamine results in increased activity of CDK2 protein CTD PMID:8463339 melatonin multiple interactions ISO RGD:70501 6480464 Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of CDK2 mRNA], Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in decreased expression of CDK2 protein] CTD PMID:23963992 , PMID:35643323 metformin multiple interactions ISO RGD:1352010 6480464 [Paclitaxel co-treated with Metformin] results in decreased expression of CDK2 mRNA CTD PMID:29309887 methotrexate increases expression ISO RGD:1352010 6480464 Methotrexate results in increased expression of CDK2 mRNA CTD PMID:17696278 methoxychlor increases expression ISO RGD:1352010 6480464 Methoxychlor results in increased expression of CDK2 mRNA CTD PMID:22552626 methoxychlor multiple interactions ISO RGD:1352010 6480464 [Methoxychlor co-treated with resveratrol] results in decreased expression of CDK2 mRNA CTD PMID:22552626 methyl isocyanate affects expression ISO RGD:1352010 6480464 methyl isocyanate affects the expression of CDK2 protein CTD PMID:19513903 methyl isocyanate increases expression ISO RGD:70501 6480464 methyl isocyanate results in increased expression of CDK2 protein CTD PMID:22223508 methylparaben increases expression ISO RGD:1352010 6480464 methylparaben results in increased expression of CDK2 mRNA CTD PMID:24481588 methylparaben decreases expression ISO RGD:70501 6480464 methylparaben results in decreased expression of CDK2 mRNA CTD PMID:33358972 methylseleninic acid multiple interactions ISO RGD:1352010 6480464 HSPA5 protein affects the reaction [methylselenic acid results in decreased expression of CDK2 protein] more ... CTD PMID:16205645 , PMID:17847021 methylseleninic acid decreases expression ISO RGD:1352010 6480464 methylselenic acid results in decreased expression of CDK2 mRNA, methylselenic acid results in decreased expression of CDK2 protein CTD PMID:12517777 , PMID:16205645 mifepristone multiple interactions ISO RGD:1352010 6480464 Mifepristone inhibits the reaction [CDK2 protein binds to CCNE1 protein] more ... CTD PMID:17545545 mitomycin C affects response to substance ISO RGD:1352010 6480464 CDK2 protein affects the susceptibility to Mitomycin CTD PMID:16217747 mono(2-ethylhexyl) phthalate multiple interactions ISO RGD:70501 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDK2 mRNA CTD PMID:31884101 monobenzyl phthalate multiple interactions ISO RGD:70501 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDK2 mRNA CTD PMID:31884101 Monobutylphthalate affects expression EXP 6480464 monobutyl phthalate affects the expression of CDK2 mRNA CTD PMID:20864626 monocrotaline multiple interactions ISO RGD:1352010 6480464 [CYP3A4 protein results in increased metabolism of Monocrotaline] which results in decreased expression of CDK2 mRNA CTD PMID:33884520 monoethyl phthalate multiple interactions ISO RGD:70501 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDK2 mRNA CTD PMID:31884101 motexafin gadolinium increases expression ISO RGD:1352010 6480464 motexafin gadolinium results in increased expression of CDK2 mRNA CTD PMID:16357179 motexafin gadolinium multiple interactions ISO RGD:1352010 6480464 motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of CDK2 mRNA] CTD PMID:16357179 N-(6-acetamidohexyl)acetamide decreases expression ISO RGD:70501 6480464 hexamethylene bisacetamide results in decreased expression of CDK2 mRNA CTD PMID:26941288 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:70501 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [troglitazone results in decreased expression of CDK2 protein] CTD PMID:15610522 N-methyl-N-nitrosourea increases activity EXP 6480464 Methylnitrosourea results in increased activity of CDK2 protein CTD PMID:15581186 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of CDK2 protein CTD PMID:11831363 , PMID:30779474 N-nitrosodiethylamine multiple interactions EXP 6480464 Hesperidin inhibits the reaction [Diethylnitrosamine results in increased expression of CDK2 protein] CTD PMID:30779474 N-nitrosodiethylamine affects expression EXP 6480464 Diethylnitrosamine affects the expression of CDK2 protein CTD PMID:26589970 N-nitrosodiethylamine increases expression ISO RGD:70501 6480464 Diethylnitrosamine results in increased expression of CDK2 mRNA, Diethylnitrosamine results in increased expression of CDK2 protein CTD PMID:17854601 N-nitrosodiethylamine multiple interactions ISO RGD:70501 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CDK2 protein more ... CTD PMID:17620307 , PMID:17854601 naphthalene multiple interactions ISO RGD:1352010 6480464 [naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] results in increased expression of CDK2 protein CTD PMID:28803881 naphthalene increases expression ISO RGD:1352010 6480464 naphthalene results in increased expression of CDK2 protein CTD PMID:28803881 naringin multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naringin results in decreased expression of CDK2 protein] more ... CTD PMID:18951945 naringin multiple interactions ISO RGD:1352010 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naringin results in increased expression of CDK2 protein] more ... CTD PMID:18296682 nelfinavir multiple interactions ISO RGD:1352010 6480464 [Nelfinavir results in increased degradation of CDC25A protein] which results in decreased activity of CDK2 protein CTD PMID:17283158 nelfinavir decreases activity ISO RGD:1352010 6480464 Nelfinavir results in decreased activity of CDK2 protein CTD PMID:17283158 nicardipine decreases activity ISO RGD:1352010 6480464 Nicardipine results in decreased activity of CDK2 protein CTD PMID:17217918 nickel atom increases expression ISO RGD:1352010 6480464 Nickel results in increased expression of CDK2 mRNA CTD PMID:25583101 niclosamide decreases expression ISO RGD:1352010 6480464 Niclosamide results in decreased expression of CDK2 protein CTD PMID:29031202 nicotine multiple interactions ISO RGD:1352010 6480464 CDK2 affects the reaction [Nicotine results in increased phosphorylation of AKT1 protein] CTD PMID:35929799 Nonylphenol multiple interactions ISO RGD:1352010 6480464 [nonylphenol co-treated with resveratrol] results in decreased expression of CDK2 mRNA CTD PMID:22552626 Nonylphenol increases expression ISO RGD:1352010 6480464 nonylphenol results in increased expression of CDK2 mRNA CTD PMID:22552626 NS-398 multiple interactions ISO RGD:1352010 6480464 N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [VEGFC protein results in increased expression of CDK2 protein] more ... CTD PMID:14566837 , PMID:24184161 NS-398 decreases activity ISO RGD:1352010 6480464 N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of CDK2 protein CTD PMID:14566837 ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of CDK2 mRNA CTD PMID:23358140 ochratoxin A decreases expression ISO RGD:1352010 6480464 ochratoxin A results in decreased expression of CDK2 protein CTD PMID:28286205 okadaic acid decreases expression ISO RGD:1352010 6480464 Okadaic Acid results in decreased expression of CDK2 mRNA CTD PMID:21512803 olomoucine multiple interactions ISO RGD:1352010 6480464 olomoucine inhibits the reaction [CDK2 protein results in increased phosphorylation of TPI1 protein] CTD PMID:20149834 olomoucine decreases activity EXP 6480464 olomoucine results in decreased activity of CDK2 protein CTD PMID:12387751 olomoucine decreases activity ISO RGD:70501 6480464 olomoucine results in decreased activity of CDK2 protein CTD PMID:15026556 omacetaxine mepesuccinate increases expression ISO RGD:1352010 6480464 Homoharringtonine results in increased expression of CDK2 protein CTD PMID:31726078 orlistat decreases expression ISO RGD:1352010 6480464 Orlistat results in decreased expression of CDK2 protein CTD PMID:30667213 ouabain decreases expression ISO RGD:1352010 6480464 Ouabain results in decreased expression of CDK2 mRNA, Ouabain results in decreased expression of CDK2 protein CTD PMID:20460749 more ... oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of CDK2 mRNA CTD PMID:25729387 oxaliplatin increases expression ISO RGD:1352010 6480464 oxaliplatin results in increased expression of CDK2 protein CTD PMID:15204521 ozone multiple interactions ISO RGD:1352010 6480464 [Oxygen co-treated with Ozone co-treated with Cannabidiol] results in decreased expression of CDK2 mRNA, [Oxygen co-treated with Ozone] results in decreased expression of CDK2 mRNA CTD PMID:32992648 paclitaxel multiple interactions ISO RGD:1352010 6480464 [Paclitaxel co-treated with Metformin] results in decreased expression of CDK2 mRNA more ... CTD PMID:10430095 more ... paclitaxel increases activity ISO RGD:1352010 6480464 Paclitaxel results in increased activity of CDK2 protein CTD PMID:10430095 , PMID:14646529 palbociclib decreases activity ISO RGD:1352010 6480464 palbociclib results in decreased activity of CDK2 protein CTD PMID:17537993 palbociclib multiple interactions ISO RGD:1352010 6480464 palbociclib results in increased phosphorylation of and results in increased expression of CDK2 protein CTD PMID:21880723 palbociclib decreases phosphorylation ISO RGD:1352010 6480464 palbociclib results in decreased phosphorylation of CDK2 protein CTD PMID:20100483 palbociclib decreases expression ISO RGD:1352010 6480464 palbociclib results in decreased expression of CDK2 protein CTD PMID:20473330 , PMID:22869556 Panduratin A decreases expression ISO RGD:1352010 6480464 panduratin A results in decreased expression of CDK2 protein CTD PMID:16497706 paracetamol multiple interactions ISO RGD:70501 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of CDK2 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CDK2 mRNA] CTD PMID:17585979 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of CDK2 mRNA CTD PMID:33387578 paraquat multiple interactions ISO RGD:70501 6480464 [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CDK2 mRNA more ... CTD PMID:23963992 , PMID:28012437 PCB138 multiple interactions ISO RGD:70501 6480464 [2 more ... CTD PMID:25510870 PCB138 affects expression ISO RGD:1352010 6480464 2 more ... CTD PMID:21703328 pentachlorophenol increases expression EXP 6480464 Pentachlorophenol results in increased expression of CDK2 mRNA CTD PMID:19442831 pentobarbital decreases expression EXP 6480464 Pentobarbital results in decreased expression of CDK2 protein CTD PMID:19346066 Pentoxifylline multiple interactions ISO RGD:1352010 6480464 Pentoxifylline inhibits the reaction [Mechlorethamine results in increased activity of [CCNA2 protein binds to CDK2 protein]] CTD PMID:8463339 perfluorononanoic acid decreases expression ISO RGD:1352010 6480464 perfluoro-n-nonanoic acid results in decreased expression of CDK2 mRNA CTD PMID:32588087 perillyl alcohol decreases expression ISO RGD:1352010 6480464 perillyl alcohol results in decreased expression of CDK2 protein CTD PMID:17138864 perillyl alcohol multiple interactions ISO RGD:1352010 6480464 perillyl alcohol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein], perillyl alcohol promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein] CTD PMID:17138864 phenanthrene increases expression ISO RGD:1352010 6480464 phenanthrene results in increased expression of CDK2 protein CTD PMID:28803881 phenanthrene multiple interactions ISO RGD:1352010 6480464 [naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] results in increased expression of CDK2 protein CTD PMID:28803881 phenethyl caffeate multiple interactions EXP 6480464 caffeic acid phenethyl ester inhibits the reaction [CDK2 protein binds to CCNE1 protein] CTD PMID:15885897 phenethyl caffeate multiple interactions ISO RGD:1352010 6480464 [Tretinoin co-treated with caffeic acid phenethyl ester] inhibits the reaction [CDK2 protein binds to CCNE1 protein] CTD PMID:16766008 phenethyl isothiocyanate decreases expression ISO RGD:1352010 6480464 phenethyl isothiocyanate results in decreased expression of CDK2 protein CTD PMID:26678675 phenobarbital multiple interactions ISO RGD:70501 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CDK2 protein, CDKN1B protein inhibits the reaction [[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CDK2 protein] CTD PMID:17620307 phenylephrine increases expression EXP 6480464 Phenylephrine results in increased expression of CDK2 protein CTD PMID:15603588 phorbol 13-acetate 12-myristate increases activity ISO RGD:1352010 6480464 Tetradecanoylphorbol Acetate results in increased activity of CDK2 protein CTD PMID:12421932 phorbol 13-acetate 12-myristate increases expression ISO RGD:1352010 6480464 Tetradecanoylphorbol Acetate results in increased expression of CDK2 protein CTD PMID:24073338 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:1352010 6480464 Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of CDK2 protein] CTD PMID:12421932 phorbol 13-acetate 12-myristate decreases phosphorylation ISO RGD:1352010 6480464 Tetradecanoylphorbol Acetate results in decreased phosphorylation of CDK2 protein CTD PMID:15978937 phosphatidylcholine multiple interactions ISO RGD:1352010 6480464 [rubitecan co-treated with Phosphatidylcholines] results in decreased expression of CDK2 protein CTD PMID:21695227 pinosylvin decreases expression ISO RGD:1352010 6480464 pinosylvin results in decreased expression of CDK2 protein CTD PMID:23333577 pioglitazone decreases expression ISO RGD:1352010 6480464 pioglitazone results in decreased expression of CDK2 protein CTD PMID:15729575 Piplartine decreases expression ISO RGD:70501 6480464 piplartine results in decreased expression of CDK2 protein CTD PMID:19501152 pirinixic acid multiple interactions ISO RGD:70501 6480464 [pirinixic acid co-treated with PPARA] results in increased expression of CDK2 mRNA CTD PMID:20813756 pirinixic acid increases expression ISO RGD:70501 6480464 pirinixic acid results in increased expression of CDK2 mRNA CTD PMID:18301758 , PMID:20813756 piroxicam multiple interactions ISO RGD:1352010 6480464 Cisplatin affects the reaction [Piroxicam results in decreased expression of CDK2 mRNA] CTD PMID:21858171 piroxicam decreases expression ISO RGD:1352010 6480464 Piroxicam results in decreased expression of CDK2 mRNA CTD PMID:21858171 potassium atom multiple interactions EXP 6480464 GW 506033X inhibits the reaction [Potassium deficiency results in increased activity of CDK2 protein] CTD PMID:19046382 potassium atom increases activity EXP 6480464 Potassium deficiency results in increased activity of CDK2 protein CTD PMID:19046382 potassium dichromate decreases expression EXP 6480464 Potassium Dichromate results in decreased expression of CDK2 mRNA CTD PMID:26348139 progesterone multiple interactions ISO RGD:1352010 6480464 Progesterone promotes the reaction [CDK2 protein binds to CDKN1A protein], Progesterone promotes the reaction [CDK2 protein binds to CDKN1B protein] CTD PMID:18850315 progesterone increases expression ISO RGD:70501 6480464 Progesterone results in increased expression of CDK2 mRNA CTD PMID:19847363 progesterone decreases activity ISO RGD:1352010 6480464 Progesterone results in decreased activity of CDK2 protein CTD PMID:18850315 propanal decreases expression ISO RGD:1352010 6480464 propionaldehyde results in decreased expression of CDK2 mRNA CTD PMID:26079696 propiconazole decreases expression ISO RGD:70501 6480464 propiconazole results in decreased expression of CDK2 mRNA CTD PMID:21278054 propylparaben increases expression ISO RGD:1352010 6480464 propylparaben results in increased expression of CDK2 mRNA CTD PMID:24481588 propylparaben decreases expression ISO RGD:70501 6480464 propylparaben results in decreased expression of CDK2 mRNA CTD PMID:33358972 pterostilbene decreases expression EXP 6480464 pterostilbene results in decreased expression of CDK2 protein CTD PMID:20398797 pyrene increases expression ISO RGD:1352010 6480464 pyrene results in increased expression of CDK2 protein CTD PMID:28803881 pyrene multiple interactions ISO RGD:1352010 6480464 [naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] results in increased expression of CDK2 protein CTD PMID:28803881 pyrrolidine dithiocarbamate decreases expression EXP 6480464 pyrrolidine dithiocarbamic acid results in decreased expression of CDK2 protein CTD PMID:14603533 quercetin multiple interactions ISO RGD:1352010 6480464 [Cisplatin co-treated with Quercetin] results in increased expression of CDK2 mRNA more ... CTD PMID:11322924 more ... quercetin decreases activity ISO RGD:1352010 6480464 Quercetin results in decreased activity of CDK2 protein CTD PMID:11322924 quercetin decreases expression ISO RGD:1352010 6480464 Quercetin results in decreased expression of CDK2 mRNA, Quercetin results in decreased expression of CDK2 protein CTD PMID:14715546 more ... quercetin 4'-O-beta-D-glucopyranoside decreases expression ISO RGD:1352010 6480464 spiraeoside results in decreased expression of CDK2 protein CTD PMID:34116102 resveratrol decreases activity ISO RGD:1352010 6480464 resveratrol results in decreased activity of CDK2 protein CTD PMID:12690110 resveratrol decreases expression ISO RGD:70501 6480464 resveratrol results in decreased expression of CDK2 protein CTD PMID:15122319 , PMID:22935344 resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of CDK2 mRNA, resveratrol results in decreased expression of CDK2 protein CTD PMID:17588540 , PMID:20972827 resveratrol increases expression ISO RGD:1352010 6480464 resveratrol results in increased expression of CDK2 CTD PMID:15583814 resveratrol multiple interactions ISO RGD:1352010 6480464 [bisphenol A co-treated with resveratrol] results in decreased expression of CDK2 mRNA more ... CTD PMID:16317118 , PMID:22552626 resveratrol decreases expression ISO RGD:1352010 6480464 resveratrol results in decreased expression of CDK2 mRNA, resveratrol results in decreased expression of CDK2 protein CTD PMID:11507064 more ... riddelliine multiple interactions ISO RGD:1352010 6480464 [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDK2 mRNA CTD PMID:33884520 ritonavir decreases expression ISO RGD:1352010 6480464 Ritonavir results in decreased expression of CDK2 mRNA, Ritonavir results in decreased expression of CDK2 protein CTD PMID:16551874 , PMID:19386116 rotenone increases expression EXP 6480464 Rotenone results in increased expression of CDK2 mRNA CTD PMID:28374803 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of CDK2 protein CTD PMID:35544339 rubimaillin decreases expression ISO RGD:1352010 6480464 rubimaillin results in decreased expression of CDK2 protein CTD PMID:35007525 rubimaillin multiple interactions ISO RGD:1352010 6480464 Glutathione inhibits the reaction [rubimaillin results in decreased expression of CDK2 protein] CTD PMID:35007525 rubitecan multiple interactions ISO RGD:1352010 6480464 [rubitecan co-treated with Phosphatidylcholines] results in decreased expression of CDK2 protein CTD PMID:21695227 ruxolitinib multiple interactions ISO RGD:1352010 6480464 [ruxolitinib co-treated with Arsenic Trioxide] results in decreased expression of CDK2 mRNA CTD PMID:30012499 SB 203580 multiple interactions ISO RGD:70501 6480464 SB 203580 inhibits the reaction [sodium arsenite results in decreased activity of CDK2 protein] CTD PMID:11807808 SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [esculetin results in decreased expression of CDK2 protein] CTD PMID:21600278 Se-methyl-L-selenocysteine multiple interactions ISO RGD:70501 6480464 selenomethylselenocysteine results in decreased phosphorylation of and results in decreased activity of CDK2 protein CTD PMID:10656618 Se-methylselenocysteine multiple interactions ISO RGD:70501 6480464 selenomethylselenocysteine results in decreased phosphorylation of and results in decreased activity of CDK2 protein CTD PMID:10656618 selenium atom decreases expression ISO RGD:1352010 6480464 Selenium deficiency results in decreased expression of CDK2 mRNA CTD PMID:11925459 selumetinib multiple interactions ISO RGD:70501 6480464 Doxorubicin promotes the reaction [AZD 6244 results in decreased expression of CDK2 protein] CTD PMID:17876044 selumetinib decreases expression ISO RGD:70501 6480464 AZD 6244 results in decreased expression of CDK2 protein CTD PMID:17876044 silibinin multiple interactions ISO RGD:1352010 6480464 [Silybin co-treated with Arsenic] results in decreased expression of CDK2 protein CTD PMID:25868784 silver atom multiple interactions ISO RGD:1352010 6480464 [Silver analog co-treated with Citric Acid] affects the expression of CDK2 mRNA CTD PMID:27021274 silver(0) multiple interactions ISO RGD:1352010 6480464 [Silver analog co-treated with Citric Acid] affects the expression of CDK2 mRNA CTD PMID:27021274 simvastatin multiple interactions EXP 6480464 geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CDK2 protein], Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of CDK2 protein] CTD PMID:26577051 simvastatin decreases expression ISO RGD:1352010 6480464 Simvastatin results in decreased expression of CDK2 protein CTD PMID:20878096 simvastatin decreases activity EXP 6480464 Simvastatin results in decreased activity of CDK2 protein CTD PMID:18804536 simvastatin multiple interactions ISO RGD:1352010 6480464 [Simvastatin results in decreased degradation of CDKN1A protein] which results in decreased activity of CDK2 protein, [Simvastatin results in decreased degradation of CDKN1B protein] which results in decreased activity of CDK2 protein CTD PMID:17928568 simvastatin decreases expression EXP 6480464 Simvastatin results in decreased expression of CDK2 protein CTD PMID:10412745 , PMID:26577051 sirolimus multiple interactions ISO RGD:1352010 6480464 [Sirolimus co-treated with TGFB1 protein] affects the localization of CDK2 protein more ... CTD PMID:12417722 , PMID:14979923 sirolimus multiple interactions ISO RGD:70501 6480464 [Sirolimus co-treated with TGFB1 protein] affects the localization of CDK2 protein more ... CTD PMID:12417722 , PMID:14979923 sirolimus decreases activity ISO RGD:1352010 6480464 Sirolimus results in decreased activity of CDK2 protein CTD PMID:12393642 , PMID:21528311 sirolimus decreases activity EXP 6480464 Sirolimus results in decreased activity of CDK2 protein CTD PMID:7532117 sodium arsenite multiple interactions ISO RGD:1352010 6480464 NFE2L2 protein affects the reaction [sodium arsenite results in increased expression of CDK2 protein] more ... CTD PMID:17545210 more ... sodium arsenite increases expression ISO RGD:1352010 6480464 sodium arsenite results in increased expression of CDK2 mRNA, sodium arsenite results in increased expression of CDK2 protein CTD PMID:28595984 more ... sodium arsenite decreases activity ISO RGD:70501 6480464 sodium arsenite results in decreased activity of CDK2 protein CTD PMID:11807808 sodium arsenite decreases expression ISO RGD:70501 6480464 sodium arsenite results in decreased expression of CDK2 protein CTD PMID:20336670 sodium arsenite multiple interactions ISO RGD:70501 6480464 SB 203580 inhibits the reaction [sodium arsenite results in decreased activity of CDK2 protein], sodium arsenite promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein] CTD PMID:11807808 sodium chromate multiple interactions ISO RGD:70501 6480464 [sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in decreased expression of CDK2 protein, Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in decreased expression of CDK2 protein] CTD PMID:35643323 sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of CDK2 mRNA CTD PMID:22561333 sodium fluoride decreases expression ISO RGD:70501 6480464 Sodium Fluoride results in decreased expression of CDK2 mRNA CTD PMID:21340527 Soman increases expression EXP 6480464 Soman results in increased expression of CDK2 mRNA CTD PMID:19281266 sorafenib decreases expression ISO RGD:1352010 6480464 sorafenib results in decreased expression of CDK2 mRNA CTD PMID:26409325 sterigmatocystin affects expression EXP 6480464 Sterigmatocystin affects the expression of CDK2 mRNA CTD PMID:34126181 sulindac multiple interactions ISO RGD:1352010 6480464 Sulindac promotes the reaction [CDKN1A protein results in decreased activity of CDK2 protein] CTD PMID:14566837 sulindac decreases activity ISO RGD:1352010 6480464 Sulindac results in decreased activity of CDK2 protein CTD PMID:14566837 sunitinib decreases expression ISO RGD:1352010 6480464 Sunitinib results in decreased expression of CDK2 mRNA CTD PMID:31533062 syringic acid decreases expression ISO RGD:1352010 6480464 syringic acid results in decreased expression of CDK2 mRNA CTD PMID:33759321 tamoxifen multiple interactions ISO RGD:1352010 6480464 [Tamoxifen co-treated with FTI 277] promotes the reaction [CDKN1A protein binds to [CCNE1 protein binds to CDK2 protein]] more ... CTD PMID:12866041 , PMID:15611077 tamoxifen decreases expression ISO RGD:1352010 6480464 Tamoxifen results in decreased expression of CDK2 mRNA CTD PMID:34821461 tamoxifen increases activity ISO RGD:70501 6480464 Tamoxifen results in increased activity of CDK2 protein CTD PMID:15642790 tamoxifen decreases activity ISO RGD:1352010 6480464 Tamoxifen results in decreased activity of CDK2 protein CTD PMID:15611077 tamoxifen increases expression ISO RGD:1352010 6480464 Tamoxifen results in increased expression of CDK2 mRNA, Tamoxifen results in increased expression of CDK2 protein CTD PMID:20215421 Tanshinone I multiple interactions ISO RGD:70501 6480464 [tanshinone co-treated with indirubin] promotes the reaction [tetraarsenic tetrasulfide results in decreased expression of CDK2 protein], [tanshinone co-treated with tetraarsenic tetrasulfide] promotes the reaction [indirubin results in decreased expression of CDK2 protein] CTD PMID:18344322 tert-butyl hydroperoxide decreases activity ISO RGD:1352010 6480464 tert-Butylhydroperoxide results in decreased activity of CDK2 protein CTD PMID:12766906 tert-butyl hydroperoxide decreases expression ISO RGD:1352010 6480464 tert-Butylhydroperoxide results in decreased expression of CDK2 mRNA CTD PMID:15336504 tert-butyl hydroperoxide multiple interactions ISO RGD:1352010 6480464 ginsenoside Rg1 affects the reaction [tert-Butylhydroperoxide affects the expression of CDK2 protein] CTD PMID:15606011 testosterone multiple interactions ISO RGD:1352010 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of CDK2 mRNA CTD PMID:21592394 testosterone decreases expression ISO RGD:1352010 6480464 Testosterone results in decreased expression of CDK2 mRNA CTD PMID:21592394 tetracaine decreases phosphorylation ISO RGD:70501 6480464 Tetracaine results in decreased phosphorylation of CDK2 protein CTD PMID:34822839 tetracaine decreases phosphorylation ISO RGD:1352010 6480464 Tetracaine results in decreased phosphorylation of CDK2 protein CTD PMID:34822839 tetracaine multiple interactions ISO RGD:70501 6480464 HNRNPA1 protein inhibits the reaction [Tetracaine results in decreased phosphorylation of CDK2 protein] CTD PMID:34822839 tetracaine multiple interactions ISO RGD:1352010 6480464 HNRNPA1 protein inhibits the reaction [Tetracaine results in decreased phosphorylation of CDK2 protein] CTD PMID:34822839 tetrachloromethane increases activity ISO RGD:70501 6480464 Carbon Tetrachloride results in increased activity of CDK2 protein CTD PMID:19887370 tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of CDK2 mRNA] CTD PMID:31150632 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of CDK2 mRNA CTD PMID:31150632 tetraphene multiple interactions EXP 6480464 benz(a)anthracene results in increased activity of [CCNA2 protein binds to CDK2 protein] CTD PMID:17141280 thapsigargin multiple interactions ISO RGD:1352010 6480464 4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in increased expression of CDK2 mRNA] more ... CTD PMID:19442820 thapsigargin decreases expression ISO RGD:1352010 6480464 Thapsigargin results in decreased expression of CDK2 mRNA CTD PMID:22378314 thapsigargin increases expression ISO RGD:1352010 6480464 Thapsigargin results in increased expression of CDK2 mRNA CTD PMID:19442820 thymoquinone decreases expression ISO RGD:1352010 6480464 thymoquinone results in decreased expression of CDK2 protein CTD PMID:32112862 Tiron increases activity ISO RGD:1352010 6480464 1 more ... CTD PMID:22785532 titanium dioxide multiple interactions ISO RGD:1352010 6480464 [Vitallium analog binds to titanium dioxide] which results in decreased expression of CDK2 mRNA CTD PMID:23825117 titanium dioxide decreases expression ISO RGD:1352010 6480464 titanium dioxide results in decreased expression of CDK2 mRNA CTD PMID:30910687 tocopherol decreases expression ISO RGD:1352010 6480464 Tocopherols results in decreased expression of CDK2 protein CTD PMID:12504091 toluene 2,4-diisocyanate increases expression ISO RGD:70501 6480464 Toluene 2, 4-Diisocyanate results in increased expression of CDK2 mRNA CTD PMID:21404309 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of CDK2 mRNA CTD PMID:25729387 trans-caffeic acid multiple interactions ISO RGD:1352010 6480464 caffeic acid promotes the reaction [Thapsigargin results in increased expression of CDK2 mRNA] CTD PMID:19442820 trans-pinosylvin decreases expression ISO RGD:1352010 6480464 pinosylvin results in decreased expression of CDK2 protein CTD PMID:23333577 trichloroethene increases methylation EXP 6480464 Trichloroethylene results in increased methylation of CDK2 gene CTD PMID:27618143 trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of CDK2 mRNA CTD PMID:33387578 trichloroethene multiple interactions ISO RGD:1352010 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Trichloroethylene results in increased expression of CDK2 protein], GJA1 protein affects the reaction [Trichloroethylene results in increased expression of CDK2 protein] CTD PMID:34896440 trichloroethene increases expression ISO RGD:1352010 6480464 Trichloroethylene results in increased expression of CDK2 protein CTD PMID:34896440 trimellitic anhydride increases expression ISO RGD:70501 6480464 trimellitic anhydride results in increased expression of CDK2 mRNA CTD PMID:19042947 Triptolide decreases expression EXP 6480464 triptolide results in decreased expression of CDK2 mRNA CTD PMID:23639586 Triptolide decreases expression ISO RGD:1352010 6480464 triptolide results in decreased expression of CDK2 protein CTD PMID:12533674 Triptolide increases expression ISO RGD:70501 6480464 triptolide results in increased expression of CDK2 protein CTD PMID:26990902 triptonide increases expression ISO RGD:70501 6480464 triptonide results in increased expression of CDK2 mRNA CTD PMID:33045310 troglitazone multiple interactions ISO RGD:1352010 6480464 [N-(4-methoxybenzyl)-N'-(5-nitro-1 more ... CTD PMID:12717389 more ... troglitazone decreases expression ISO RGD:70501 6480464 troglitazone results in decreased expression of CDK2 protein CTD PMID:15610522 troglitazone multiple interactions ISO RGD:70501 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [troglitazone results in decreased expression of CDK2 protein], troglitazone results in increased degradation of and results in increased ubiquitination of CDK2 protein CTD PMID:15610522 troglitazone decreases activity ISO RGD:1352010 6480464 troglitazone results in decreased activity of CDK2 protein CTD PMID:11343236 , PMID:12717389 troglitazone increases activity ISO RGD:1352010 6480464 troglitazone results in increased activity of CDK2 protein CTD PMID:11741176 troglitazone decreases expression ISO RGD:1352010 6480464 troglitazone results in decreased expression of CDK2 mRNA, troglitazone results in decreased expression of CDK2 protein CTD PMID:12595159 more ... Tryptanthrine decreases expression ISO RGD:1352010 6480464 tryptanthrine results in decreased expression of CDK2 mRNA, tryptanthrine results in decreased expression of CDK2 protein CTD PMID:26341616 tunicamycin decreases expression ISO RGD:1352010 6480464 Tunicamycin results in decreased expression of CDK2 mRNA CTD PMID:22378314 tyrphostin AG 1478 multiple interactions ISO RGD:1352010 6480464 RTKI cpd inhibits the reaction [Cadmium Chloride results in increased expression of CDK2 protein], RTKI cpd inhibits the reaction [EGF protein results in increased expression of CDK2 protein] CTD PMID:26385184 usnic acid decreases expression ISO RGD:1352010 6480464 usnic acid results in decreased expression of CDK2 protein CTD PMID:27369375 valproic acid decreases expression ISO RGD:1352010 6480464 Valproic Acid results in decreased expression of CDK2 mRNA CTD PMID:22580532 valproic acid affects expression ISO RGD:1352010 6480464 Valproic Acid affects the expression of CDK2 mRNA CTD PMID:25979313 vincaleukoblastine affects response to substance ISO RGD:1352010 6480464 CDK2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 vincristine decreases expression ISO RGD:1352010 6480464 Vincristine results in decreased expression of CDK2 mRNA CTD PMID:23649840 wogonin decreases expression EXP 6480464 wogonin results in decreased expression of CDK2 protein CTD PMID:23872260 wogonin decreases expression ISO RGD:1352010 6480464 wogonin results in decreased expression of CDK2 protein CTD PMID:23872260 wortmannin decreases expression ISO RGD:70501 6480464 wortmannin results in decreased expression of CDK2 protein CTD PMID:17129604 wortmannin multiple interactions ISO RGD:1352010 6480464 [2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3 more ... CTD PMID:26385184 wortmannin decreases activity ISO RGD:70501 6480464 wortmannin results in decreased activity of CDK2 protein CTD PMID:17129604 zebularine decreases expression ISO RGD:1352010 6480464 pyrimidin-2-one beta-ribofuranoside results in decreased expression of CDK2 protein CTD PMID:23320119 zinc acetate multiple interactions ISO RGD:1352010 6480464 motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of CDK2 mRNA] CTD PMID:16357179 zinc acetate increases expression ISO RGD:1352010 6480464 Zinc Acetate results in increased expression of CDK2 mRNA CTD PMID:16357179 zoledronic acid multiple interactions ISO RGD:70501 6480464 [zoledronic acid co-treated with Doxorubicin] results in decreased expression of CDK2 protein CTD PMID:19789217
