GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70486
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdk2
Name: cyclin dependent kinase 2
Acc ID: CHEBI:47217
Term: arsane
Definition: An arsine that has formula 77.94542.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects methylationISORGD:13520106480464CTDArsenic affects the methylation of CDK2 gene

PMID:25304211
multiple interactionsISORGD:13520106480464CTD[silybin co-treated with Arsenic] results in decreased expression of CDK2 protein

PMID:25868784
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.