GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cdk2 | increases expression | ISO | CDK2 (Homo sapiens) | 6480464 | CTD | fulvestrant results in increased expression of CDK2 mRNA | PMID:20215421 | Cdk2 | multiple interactions | ISO | CDK2 (Homo sapiens) | 6480464 | CTD | [bisphenol F co-treated with Fulvestrant] results in increased methylation of CDK2 gene; Fulvestrant inhibits the reaction [DDT results in increased phosphorylation of and results in increased activity of CDK2 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of and results in increased activity of CDK2 protein] | PMID:31601247 PMID:9049186 | |
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