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Gene: Cdk2 (cyclin-dependent kinase 2) Mus musculus
Symbol: Cdk2
Name: cyclin-dependent kinase 2
Description: Exhibits cyclin binding activity; cyclin-dependent protein serine/threonine kinase activity; and magnesium ion binding activity. Predicted to contribute to histone kinase activity. Involved in several processes, including G1/S transition of mitotic cell cycle; peptidyl-serine phosphorylation; and regulation of cellular macromolecule biosynthetic process. Localizes to several cellular components, including chromosome; cyclin-dependent protein kinase holoenzyme complex; and transcription regulator complex. Is expressed in several structures, including brain; branchial arch; ear; gut gland; and integumental system. Human ortholog(s) of this gene implicated in prostate cancer and renal cell carcinoma. Orthologous to human CDK2 (cyclin dependent kinase 2); PARTICIPATES IN G1/S transition pathway; interleukin-2 signaling pathway; mTOR signaling pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 14-Deoxy-11,12-didehydroandrographolide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A630093N05Rik; cell division protein kinase 2
Homo sapiens (human) : CDK2 (cyclin dependent kinase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cdk2 (cyclin dependent kinase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdk2 (cyclin dependent kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CDK2 (cyclin dependent kinase 2)
Canis lupus familiaris (dog) : CDK2 (cyclin dependent kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdk2 (cyclin dependent kinase 2)
Sus scrofa (pig) : CDK2 (cyclin dependent kinase 2)
Chlorocebus sabaeus (African green monkey) : CDK2 (cyclin dependent kinase 2)
Heterocephalus glaber (naked mole-rat) : Cdk2 (cyclin dependent kinase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl10128,697,939 - 128,705,031 (-)EnsemblGRCm38mm10GRCm38
GRCm3810128,697,938 - 128,705,051 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3710128,134,995 - 128,142,107 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610128,100,888 - 128,107,961 (-)NCBImm8
Celera10131,090,071 - 131,097,183 (-)NCBICelera
Cytogenetic Map10D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cdk2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70501
Created: 2002-05-02
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.