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Gene: CDK2 (cyclin dependent kinase 2) Homo sapiens
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Symbol: CDK2
Name: cyclin dependent kinase 2
Description: This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cdc2-related protein kinase; CDKN2; cell devision kinase 2; cell division protein kinase 2; cyclin-dependent kinase 2; p33 protein kinase; p33(CDK2)
Orthologs:
Mus musculus (house mouse) : Cdk2 (cyclin-dependent kinase 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cdk2 (cyclin dependent kinase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdk2 (cyclin dependent kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CDK2 (cyclin dependent kinase 2)
Canis lupus familiaris (dog) : CDK2 (cyclin dependent kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdk2 (cyclin dependent kinase 2)
Sus scrofa (pig) : CDK2 (cyclin dependent kinase 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381255,966,769 - 55,972,789 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371256,360,556 - 56,366,573 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361254,646,826 - 54,652,835 (+)NCBINCBI36hg18NCBI36
Build 341254,646,825 - 54,652,834NCBI
Celera1256,013,264 - 56,019,276 (+)NCBI
Cytogenetic Map12q13.2NCBI
HuRef1253,399,466 - 53,405,479 (+)NCBIHuRef
CHM1_11256,327,686 - 56,333,684 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Genomics

Comparative Map Data
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miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CDK2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1352010
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.