Cdk2 (cyclin dependent kinase 2) - Rat Genome Database

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Gene: Cdk2 (cyclin dependent kinase 2) Ictidomys tridecemlineatus
Analyze
Symbol: Cdk2
Name: cyclin dependent kinase 2
RGD ID: 12572193
Description: ENCODES a protein that exhibits cyclin binding (ortholog); cyclin-dependent protein kinase activity (ortholog); cyclin-dependent protein serine/threonine kinase activity (ortholog); INVOLVED IN animal organ regeneration (ortholog); cellular response to insulin stimulus (ortholog); centriole replication (ortholog); PARTICIPATES IN G1/S transition pathway; interleukin-2 signaling pathway; mTOR signaling pathway; ASSOCIATED WITH breast cancer (ortholog); Endometrial Neoplasms (ortholog); Endometrioid Carcinomas (ortholog); FOUND IN Cajal body (ortholog); centrosome (ortholog); chromosome, telomeric region (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: cyclin dependent kinase 2, transcript variant X1; cyclin dependent kinase 2, transcript variant X2; cyclin-dependent kinase 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494558,484,370 - 58,490,389 (-)NCBI
SpeTri2.0NW_004936646379,849 - 385,648 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Cdk2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494558,484,370 - 58,490,389 (-)NCBI
SpeTri2.0NW_004936646379,849 - 385,648 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1255,966,781 - 55,972,789 (+)EnsemblGRCh38hg38GRCh38
GRCh381255,966,830 - 55,972,789 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371256,360,614 - 56,366,573 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361254,646,826 - 54,652,835 (+)NCBINCBI36hg18NCBI36
Build 341254,646,825 - 54,652,834NCBI
Celera1256,013,264 - 56,019,276 (+)NCBI
Cytogenetic Map12q13.2NCBI
HuRef1253,399,466 - 53,405,479 (+)NCBIHuRef
CHM1_11256,327,689 - 56,333,679 (+)NCBICHM1_1
Cdk2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910128,533,807 - 128,540,920 (-)NCBIGRCm39mm39
GRCm39 Ensembl10128,533,808 - 128,540,900 (-)Ensembl
GRCm3810128,697,938 - 128,705,051 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,697,939 - 128,705,031 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710128,134,995 - 128,142,107 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610128,100,888 - 128,107,961 (-)NCBImm8
Celera10131,090,071 - 131,097,183 (-)NCBICelera
Cytogenetic Map10D3NCBI
Cdk2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.271,129,878 - 1,137,431 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl71,129,811 - 1,137,403 (-)Ensembl
Rnor_6.073,124,953 - 3,132,533 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl73,124,954 - 3,132,457 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.073,097,653 - 3,105,210 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.472,000,196 - 2,007,682 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.172,000,196 - 2,007,682 (-)NCBI
Celera71,000,083 - 1,007,560 (-)NCBICelera
Cytogenetic Map7q11NCBI
Cdk2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554583,555,603 - 3,562,120 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554583,555,603 - 3,561,063 (+)NCBIChiLan1.0ChiLan1.0
CDK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11233,189,934 - 33,195,945 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1233,189,934 - 33,195,945 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01232,940,225 - 32,946,236 (-)NCBIMhudiblu_PPA_v0panPan3
CDK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.110300,863 - 306,546 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl10300,903 - 305,438 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha10362,779 - 368,479 (+)NCBI
ROS_Cfam_1.010307,657 - 313,366 (+)NCBI
UMICH_Zoey_3.110285,465 - 291,170 (+)NCBI
UNSW_CanFamBas_1.010528,243 - 533,942 (+)NCBI
UU_Cfam_GSD_1.010652,514 - 658,220 (+)NCBI
CDK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl521,365,763 - 21,392,726 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1521,365,723 - 21,372,170 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2522,941,174 - 22,947,591 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11151,905,085 - 51,910,209 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1151,905,115 - 51,909,907 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037194,076,082 - 194,082,105 (-)NCBIVero_WHO_p1.0
Cdk2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462480212,076,443 - 12,082,608 (-)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005335606   ⟹   XP_005335663
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494558,484,370 - 58,490,389 (-)NCBI
SpeTri2.0NW_004936646379,849 - 385,648 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005335607   ⟹   XP_005335664
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494558,484,370 - 58,490,388 (-)NCBI
SpeTri2.0NW_004936646379,849 - 385,648 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005335663 (Get FASTA)   NCBI Sequence Viewer  
  XP_005335664 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3291661 (Get FASTA)   NCBI Sequence Viewer  
  KAG3291662 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005335663   ⟸   XM_005335606
- Peptide Label: isoform X1
- UniProtKB: A0A287D5T7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005335664   ⟸   XM_005335607
- Peptide Label: isoform X2
- UniProtKB: I3LWC0 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000000298 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000000264 ENTREZGENE, UniProtKB/TrEMBL
  ENSSTOP00000028881 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000000295 UniProtKB/TrEMBL
  ENSSTOT00000034134 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene Cdk2 ENTREZGENE
Pfam Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A287D5T7 ENTREZGENE, UniProtKB/TrEMBL
  I3LWC0 ENTREZGENE, UniProtKB/TrEMBL