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Gene: Ccne1 (cyclin E1) Rattus norvegicus
Symbol: Ccne1
Name: cyclin E1
Description: Exhibits protein kinase binding activity. Involved in several processes, including animal organ development; response to nutrient; and response to steroid hormone. Localizes to centrosome; cytoplasm; and nucleus. Biomarker of hepatocellular carcinoma; hypertension; and ovarian carcinoma. Human ortholog(s) of this gene implicated in breast adenocarcinoma. Orthologous to human CCNE1 (cyclin E1); PARTICIPATES IN G1/S transition pathway; mTOR signaling pathway; cell cycle pathway, mitotic; INTERACTS WITH (-)-citrinin; (R)-mevalonic acid; (Z)-3-butylidenephthalide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ccne; CYCLE; cyclin E; G1/S-specific cyclin-E1
Homo sapiens (human) : CCNE1 (cyclin E1)  HGNC  Alliance
Mus musculus (house mouse) : Ccne1 (cyclin E1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ccne1 (cyclin E1)
Pan paniscus (bonobo/pygmy chimpanzee) : CCNE1 (cyclin E1)
Canis lupus familiaris (dog) : CCNE1 (cyclin E1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ccne1 (cyclin E1)
Sus scrofa (pig) : CCNE1 (cyclin E1)
Chlorocebus sabaeus (African green monkey) : CCNE1 (cyclin E1)
Heterocephalus glaber (naked mole-rat) : Ccne1 (cyclin E1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0194,485,830 - 94,495,112 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl194,485,832 - 94,494,980 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0195,575,136 - 95,584,387 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4190,568,189 - 90,577,426 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1190,646,304 - 90,655,502 (-)NCBI
Celera185,114,968 - 85,124,206 (-)NCBICelera
Cytogenetic Map1q21NCBI
RH 3.4 Map1885.7RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ccne1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2294
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.