GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70486
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdk2
Name: cyclin dependent kinase 2
Acc ID: CHEBI:39106
Term: pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of four fused benzene rings, resulting in a flat aromatic system.
Chemical ID: MESH:C030984
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:13520106480464CTDpyrene results in increased expression of CDK2 protein

PMID:28803881
multiple interactionsISORGD:13520106480464CTD[naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] results in increased expression of CDK2 protein

PMID:28803881
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.