CDK2 (cyclin dependent kinase 2) - Rat Genome Database

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Gene: CDK2 (cyclin dependent kinase 2) Sus scrofa
Analyze
Symbol: CDK2
Name: cyclin dependent kinase 2
RGD ID: 13949696
Description: ENCODES a protein that exhibits cyclin binding (ortholog); cyclin-dependent protein serine/threonine kinase activity (ortholog); histone kinase activity (ortholog); INVOLVED IN negative regulation of cellular protein catabolic process; positive regulation of meiotic cell cycle process involved in oocyte maturation; animal organ regeneration (ortholog); PARTICIPATES IN G1/S transition pathway; interleukin-2 signaling pathway; mTOR signaling pathway; ASSOCIATED WITH breast cancer (ortholog); Endometrial Neoplasms (ortholog); Endometrioid Carcinomas (ortholog); FOUND IN cyclin A2-CDK2 complex (ortholog); cytosol (ortholog); intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cyclin-dependent kinase 2; cyclin-dependent kinase-2 alpha; porcine cyclin dependent kinase 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl521,365,763 - 21,392,726 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1521,365,723 - 21,372,170 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2522,941,174 - 22,947,591 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:15750306   PMID:23836398   PMID:27307074  


Genomics

Comparative Map Data
CDK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl521,365,763 - 21,392,726 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1521,365,723 - 21,372,170 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2522,941,174 - 22,947,591 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1255,966,781 - 55,972,789 (+)EnsemblGRCh38hg38GRCh38
GRCh381255,966,830 - 55,972,789 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371256,360,614 - 56,366,573 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361254,646,826 - 54,652,835 (+)NCBINCBI36hg18NCBI36
Build 341254,646,825 - 54,652,834NCBI
Celera1256,013,264 - 56,019,276 (+)NCBI
Cytogenetic Map12q13.2NCBI
HuRef1253,399,466 - 53,405,479 (+)NCBIHuRef
CHM1_11256,327,689 - 56,333,679 (+)NCBICHM1_1
Cdk2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910128,533,807 - 128,540,920 (-)NCBIGRCm39mm39
GRCm39 Ensembl10128,533,808 - 128,540,900 (-)Ensembl
GRCm3810128,697,938 - 128,705,051 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,697,939 - 128,705,031 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710128,134,995 - 128,142,107 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610128,100,888 - 128,107,961 (-)NCBImm8
Celera10131,090,071 - 131,097,183 (-)NCBICelera
Cytogenetic Map10D3NCBI
Cdk2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.271,129,878 - 1,137,431 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl71,129,811 - 1,137,403 (-)Ensembl
Rnor_6.073,124,953 - 3,132,533 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl73,124,954 - 3,132,457 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.073,097,653 - 3,105,210 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.472,000,196 - 2,007,682 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.172,000,196 - 2,007,682 (-)NCBI
Celera71,000,083 - 1,007,560 (-)NCBICelera
Cytogenetic Map7q11NCBI
Cdk2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554583,555,603 - 3,562,120 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554583,555,603 - 3,561,063 (+)NCBIChiLan1.0ChiLan1.0
CDK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11233,189,934 - 33,195,945 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1233,189,934 - 33,195,945 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01232,940,225 - 32,946,236 (-)NCBIMhudiblu_PPA_v0panPan3
CDK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.110300,863 - 306,546 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl10300,903 - 305,438 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha10362,779 - 368,479 (+)NCBI
ROS_Cfam_1.010307,657 - 313,366 (+)NCBI
ROS_Cfam_1.0 Ensembl10307,694 - 312,540 (+)Ensembl
UMICH_Zoey_3.110285,465 - 291,170 (+)NCBI
UNSW_CanFamBas_1.010528,243 - 533,942 (+)NCBI
UU_Cfam_GSD_1.010652,514 - 658,220 (+)NCBI
Cdk2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494558,484,370 - 58,490,389 (-)NCBI
SpeTri2.0NW_004936646379,849 - 385,648 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11151,905,085 - 51,910,209 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1151,905,115 - 51,909,907 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037194,076,082 - 194,082,105 (-)NCBIVero_WHO_p1.0
Cdk2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462480212,076,443 - 12,082,608 (-)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: NM_001285465   ⟹   NP_001272394
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1521,365,830 - 21,372,003 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003126260   ⟹   XP_003126308
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1521,365,763 - 21,372,170 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005655594   ⟹   XP_005655651
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1521,365,723 - 21,372,170 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001272394 (Get FASTA)   NCBI Sequence Viewer  
  XP_003126308 (Get FASTA)   NCBI Sequence Viewer  
  XP_005655651 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AGR86101 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005655651   ⟸   XM_005655594
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_003126308   ⟸   XM_003126260
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: NP_001272394   ⟸   NM_001285465
- UniProtKB: A0A287AXP1 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000037597 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070029769 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000000392 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000046635 UniProtKB/TrEMBL
  ENSSSCP00000048647 UniProtKB/TrEMBL
  ENSSSCP00000053609 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000067529 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070050998 UniProtKB/TrEMBL
  ENSSSCP00070051000 UniProtKB/TrEMBL
  ENSSSCP00070051001 UniProtKB/TrEMBL
  ENSSSCP00070051002 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000000398 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000051490 UniProtKB/TrEMBL
  ENSSSCT00000053267 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000057759 UniProtKB/TrEMBL
  ENSSSCT00000081653 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070059853 UniProtKB/TrEMBL
  ENSSSCT00070059856 UniProtKB/TrEMBL
  ENSSSCT00070059857 UniProtKB/TrEMBL
  ENSSSCT00070059858 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
KEGG Report ssc:100154715 UniProtKB/TrEMBL
NCBI Gene CDK2 ENTREZGENE
Pfam Pkinase UniProtKB/TrEMBL
  Ras UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
SMART RHO UniProtKB/TrEMBL
  S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
TIGRFAMs small_GTP UniProtKB/TrEMBL
UniProt A0A287ARC7_PIG UniProtKB/TrEMBL
  A0A287AXP1 ENTREZGENE, UniProtKB/TrEMBL
  A0A287BB95_PIG UniProtKB/TrEMBL
  A0A4X1W3W2_PIG UniProtKB/TrEMBL
  A0A4X1W9B6_PIG UniProtKB/TrEMBL
  A0A4X1W9I0_PIG UniProtKB/TrEMBL
  A0A4X1W9S8_PIG UniProtKB/TrEMBL
  A0A5G2QRI3_PIG UniProtKB/TrEMBL
  F1SPH6_PIG UniProtKB/TrEMBL
  U3M3E7_PIG UniProtKB/TrEMBL