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Gene: CDK2 (cyclin dependent kinase 2) Sus scrofa

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Symbol:

CDK2

Name:

cyclin dependent kinase 2

RGD ID:

13949696

Description:

ENCODES a protein that exhibits cyclin binding (ortholog); cyclin-dependent protein serine/threonine kinase activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN negative regulation of protein catabolic process; positive regulation of meiotic cell cycle process involved in oocyte maturation; cellular response to insulin stimulus (ortholog); PARTICIPATES IN G1/S transition pathway; interleukin-2 signaling pathway; mTOR signaling pathway; ASSOCIATED WITH breast cancer (ortholog); Embryo Loss (ortholog); Endometrial Neoplasms (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH paraquat

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

cyclin-dependent kinase 2; cyclin-dependent kinase-2 alpha; porcine cyclin dependent kinase 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	21,365,764 - 21,372,168 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	21,365,723 - 21,372,170 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	22,941,174 - 22,947,591 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CDK2	Pig	breast cancer	disease_progression	ISO	CDK2 (Homo sapiens)	9068941		RGD	PMID:18236071 and REF_RGD_ID:2293557
CDK2	Pig	Endometrial Neoplasms	disease_progression	ISO	CDK2 (Homo sapiens)	9068941	protein:increased expression:endometrium	RGD	PMID:17483252 and REF_RGD_ID:2289230
CDK2	Pig	Endometrioid Carcinomas	severity	ISO	CDK2 (Homo sapiens)	9068941		RGD	PMID:9673386 and REF_RGD_ID:2298990
CDK2	Pig	Experimental Liver Cirrhosis		ISO	Cdk2 (Rattus norvegicus)	9068941		RGD	PMID:16534847 and REF_RGD_ID:2289284
CDK2	Pig	Experimental Mammary Neoplasms		ISO	Cdk2 (Mus musculus)	9068941		RGD	PMID:16924466 and REF_RGD_ID:2293558
CDK2	Pig	interstitial cystitis		ISO	Cdk2 (Rattus norvegicus)	9068941	protein:increased expression:urinary bladder:	RGD	PMID:38842512 and REF_RGD_ID:407445927
CDK2	Pig	Intimal Hyperplasia	treatment	ISO	Cdk2 (Mus musculus)	9068941		RGD	PMID:8104336 and REF_RGD_ID:10448975
CDK2	Pig	membranoproliferative glomerulonephritis		ISO	Cdk2 (Rattus norvegicus)	9068941		RGD	PMID:17893107 and REF_RGD_ID:2293563
CDK2	Pig	Optic Nerve Injuries		ISO	Cdk2 (Rattus norvegicus)	9068941	mRNA:increased expression:retina	RGD	PMID:16723461 and REF_RGD_ID:2293567
CDK2	Pig	Ovarian Neoplasms	disease_progression	ISO	CDK2 (Homo sapiens)	9068941	protein:increased expression:ovary	RGD	PMID:11585414 and REF_RGD_ID:2298988
CDK2	Pig	Ovarian Neoplasms		ISO	CDK2 (Homo sapiens)	9068941	DNA more ...	RGD	PMID:9426687 and REF_RGD_ID:2298989
CDK2	Pig	prostate cancer		ISO	CDK2 (Homo sapiens)	9068941		RGD	PMID:16648554 and REF_RGD_ID:2293560
CDK2	Pig	renal cell carcinoma		ISO	CDK2 (Homo sapiens)	9068941		RGD	PMID:16740772 and REF_RGD_ID:2293561
CDK2	Pig	Uterine Cervical Neoplasms		ISO	CDK2 (Homo sapiens)	9068941	mRNA:decreased expression:uterine cervix	RGD	PMID:18299147 and REF_RGD_ID:2296067

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CDK2	Pig	Embryo Loss		ISO	CDK2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:35038060
CDK2	Pig	Habitual Abortions		ISO	CDK2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:35038060
CDK2	Pig	head and neck squamous cell carcinoma		ISO	CDK2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:29464035
CDK2	Pig	melanoma		ISO	CDK2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:21559390
CDK2	Pig	Triple Negative Breast Neoplasms		ISO	CDK2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:33727089

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CDK2	Pig	paraquat	increases expression	EXP		6480464	Paraquat results in increased expression of CDK2 protein	CTD	PMID:34811946
CDK2	Pig	paraquat	multiple interactions	EXP		6480464	MYD88 protein affects the reaction [Paraquat results in increased expression of CDK2 protein]	CTD	PMID:34811946

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CDK2	Pig	cell division	involved_in	IEA	UniProtKB-KW:KW-0132	150520179		UniProt	GO_REF:0000043
CDK2	Pig	cellular response to insulin stimulus		ISO	Cdk2 (Rattus norvegicus)	9068941		RGD	PMID:15994754 and REF_RGD_ID:2293572
CDK2	Pig	centriole replication	involved_in	IEA	UniProtKB:P24941 and ensembl:ENSP00000266970	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	chromatin remodeling	involved_in	IEA	GO:0035173	150520179		GOC	GO_REF:0000108
CDK2	Pig	DNA damage response		ISO	Cdk2 (Rattus norvegicus)	9068941		RGD	PMID:19151707 and REF_RGD_ID:10053571
CDK2	Pig	DNA damage response	involved_in	IEA	UniProtKB-KW:KW-0227	150520179		UniProt	GO_REF:0000043
CDK2	Pig	DNA repair	involved_in	IEA	UniProtKB-KW:KW-0234	150520179		UniProt	GO_REF:0000043
CDK2	Pig	DNA synthesis involved in mitotic DNA replication		ISO	Cdk2 (Rattus norvegicus)	9068941		RGD	PMID:15696186 and REF_RGD_ID:2301349
CDK2	Pig	DNA-templated transcription	acts_upstream_of	IEA	UniProtKB:P97377 and ensembl:ENSMUSP00000026415	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	G1/S transition of mitotic cell cycle	involved_in	IBA	CGD:CAL0000191263 more ...	150520179		GO_Central	GO_REF:0000033
CDK2	Pig	G1/S transition of mitotic cell cycle	acts_upstream_of_or_within	IEA	UniProtKB:P97377 and ensembl:ENSMUSP00000026415	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	lens development in camera-type eye		ISO	Cdk2 (Rattus norvegicus)	9068941		RGD	PMID:10620399 and REF_RGD_ID:724665
CDK2	Pig	liver regeneration		ISO	Cdk2 (Rattus norvegicus)	9068941		RGD	PMID:15696186 more ...
CDK2	Pig	meiotic cell cycle	involved_in	IEA	UniProtKB-KW:KW-0469	150520179		UniProt	GO_REF:0000043
CDK2	Pig	negative regulation of protein catabolic process	involved_in	IMP		150520179	PMID:15750306	AgBase	PMID:15750306
CDK2	Pig	negative regulation of transcription by RNA polymerase II	acts_upstream_of_or_within	IEA	UniProtKB:P97377 and ensembl:ENSMUSP00000026415	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	peptidyl-serine phosphorylation	involved_in	ISO	CDK2 (Homo sapiens)	9068941	PMID:23184662	UniProt	PMID:23184662
CDK2	Pig	peptidyl-serine phosphorylation	involved_in	ISO	Cdk2 (Mus musculus)	9068941	PMID:23599433	UniProt	PMID:23599433
CDK2	Pig	positive regulation of cell population proliferation	involved_in	IEA	UniProtKB:P24941 more ...	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	positive regulation of DNA-templated DNA replication initiation	acts_upstream_of_or_within	IEA	UniProtKB:P97377 and ensembl:ENSMUSP00000026415	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	positive regulation of DNA-templated transcription	acts_upstream_of_or_within	IEA	UniProtKB:P97377 and ensembl:ENSMUSP00000026415	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	positive regulation of heterochromatin formation	involved_in	IEA	UniProtKB:P24941 and ensembl:ENSP00000266970	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	positive regulation of meiotic cell cycle process involved in oocyte maturation	involved_in	IMP		150520179	PMID:15750306	AgBase	PMID:15750306
CDK2	Pig	post-translational protein modification	involved_in	IEA	UniProtKB:P24941 and ensembl:ENSP00000266970	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	potassium ion transport	acts_upstream_of_or_within	IEA	UniProtKB:P97377 and ensembl:ENSMUSP00000026415	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	protein phosphorylation	acts_upstream_of_or_within	ISO	Cdk2 (Mus musculus)	9068941	PMID:12124778	MGI	PMID:12124778
CDK2	Pig	protein phosphorylation	involved_in	ISO	CDK2 (Homo sapiens)	9068941	PMID:12944431 and PMID:28666995	UniProt	PMID:12944431 and PMID:28666995
CDK2	Pig	protein phosphorylation	involved_in	ISO	CDK2 (Homo sapiens)	9068941	PMID:29203878	UniProt	PMID:29203878
CDK2	Pig	Ras protein signal transduction	involved_in	IEA	UniProtKB:P24941 and ensembl:ENSP00000266970	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	regulation of cell cycle	involved_in	IEA	GO:0004693 and GO:0097472	150520179		GOC	GO_REF:0000108
CDK2	Pig	regulation of G2/M transition of mitotic cell cycle	involved_in	IBA	PANTHER:PTN000623979 more ...	150520179		GO_Central	GO_REF:0000033
CDK2	Pig	regulation of gene expression	involved_in	IBA	MGI:104772 more ...	150520179		GO_Central	GO_REF:0000033
CDK2	Pig	response to cadmium ion		ISO	Cdk2 (Rattus norvegicus)	9068941		RGD	PMID:16730872 and REF_RGD_ID:2293566
CDK2	Pig	response to cAMP		ISO	Cdk2 (Rattus norvegicus)	9068941		RGD	PMID:15994754 and REF_RGD_ID:2293572
CDK2	Pig	response to electrical stimulus		ISO	Cdk2 (Rattus norvegicus)	9068941		RGD	PMID:15607308 and REF_RGD_ID:2293569
CDK2	Pig	response to estradiol		ISO	Cdk2 (Rattus norvegicus)	9068941		RGD	PMID:16019103 and REF_RGD_ID:2289288
CDK2	Pig	response to ethanol		ISO	Cdk2 (Rattus norvegicus)	9068941		RGD	PMID:16689928 and REF_RGD_ID:2289282
CDK2	Pig	response to toxic substance		ISO	Cdk2 (Rattus norvegicus)	9068941		RGD	PMID:17343987 and REF_RGD_ID:2293565
CDK2	Pig	response to xenobiotic stimulus		ISO	Cdk2 (Rattus norvegicus)	9068941		RGD	PMID:17706465 and REF_RGD_ID:2293564
CDK2	Pig	signal transduction	involved_in	IBA	MGI:1277162 more ...	150520179		GO_Central	GO_REF:0000033
CDK2	Pig	telomere maintenance in response to DNA damage	involved_in	IEA	UniProtKB:P24941 and ensembl:ENSP00000266970	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CDK2	Pig	Cajal body	located_in	IEA	UniProtKB:P24941 and ensembl:ENSP00000266970	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	Cajal body	located_in	IEA	UniProtKB-SubCell:SL-0031	150520179		UniProt	GO_REF:0000044
CDK2	Pig	centrosome	located_in	IEA	UniProtKB:P24941 and ensembl:ENSP00000266970	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	centrosome	located_in	IEA	UniProtKB-SubCell:SL-0048	150520179		UniProt	GO_REF:0000044
CDK2	Pig	chromosome, telomeric region	located_in	IEA	UniProtKB:P97377 and ensembl:ENSMUSP00000026415	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	condensed chromosome	located_in	IEA	UniProtKB:P97377 and ensembl:ENSMUSP00000026415	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	cyclin A1-CDK2 complex	part_of	IEA	UniProtKB:P97377 and ensembl:ENSMUSP00000026415	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	cyclin A2-CDK2 complex	part_of	IEA	UniProtKB:P24941 more ...	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	cyclin E1-CDK2 complex	part_of	IEA	UniProtKB:P24941 more ...	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	cyclin E2-CDK2 complex	part_of	IEA	UniProtKB:P24941 more ...	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	cyclin-dependent protein kinase holoenzyme complex	part_of	IBA	MGI:104772 more ...	150520179		GO_Central	GO_REF:0000033
CDK2	Pig	cyclin-dependent protein kinase holoenzyme complex	part_of	IEA	UniProtKB:P24941 more ...	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	cytoplasm	located_in	IEA	UniProtKB:P24941 and ensembl:ENSP00000266970	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	cytoplasm	located_in	IEA	UniProtKB-KW:KW-0963	150520179		UniProt	GO_REF:0000043
CDK2	Pig	cytoplasm	is_active_in	IBA	PANTHER:PTN000623979 more ...	150520179		GO_Central	GO_REF:0000033
CDK2	Pig	cytoskeleton	located_in	IEA	UniProtKB-KW:KW-0206	150520179		UniProt	GO_REF:0000043
CDK2	Pig	endosome	located_in	IEA	UniProtKB:P24941 and ensembl:ENSP00000266970	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	endosome	located_in	IEA	UniProtKB-SubCell:SL-0101	150520179		UniProt	GO_REF:0000044
CDK2	Pig	endosome	located_in	IEA	UniProtKB-KW:KW-0967	150520179		UniProt	GO_REF:0000043
CDK2	Pig	male germ cell nucleus	located_in	IEA	UniProtKB:P97377 and ensembl:ENSMUSP00000026415	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	nuclear envelope	located_in	IEA	UniProtKB:P97377 and ensembl:ENSMUSP00000026415	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	nucleoplasm	located_in	IEA	UniProtKB:P24941 and ensembl:ENSP00000266970	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	nucleus		ISO	Cdk2 (Rattus norvegicus)	9068941		RGD	PMID:15696186 and REF_RGD_ID:2301349
CDK2	Pig	nucleus	located_in	IEA	UniProtKB:P24941 more ...	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	nucleus	is_active_in	IBA	FB:FBgn0015618 more ...	150520179		GO_Central	GO_REF:0000033
CDK2	Pig	transcription regulator complex	part_of	IEA	UniProtKB:P97377 and ensembl:ENSMUSP00000026415	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	X chromosome	located_in	IEA	UniProtKB:P97377 and ensembl:ENSMUSP00000026415	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	Y chromosome	located_in	IEA	UniProtKB:P97377 and ensembl:ENSMUSP00000026415	150520179		Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CDK2	Pig	ATP binding	enables	IEA	UniProtKB-KW:KW-0067	150520179		UniProt	GO_REF:0000043
CDK2	Pig	ATP binding	enables	IEA	InterPro:IPR000719 and InterPro:IPR017441	150520179		InterPro	GO_REF:0000002
CDK2	Pig	ATP binding	enables	IEA	UniRule:UR001503341	150520179		UniProt	GO_REF:0000104
CDK2	Pig	cyclin binding	enables	IBA	FB:FBgn0016131 more ...	150520179		GO_Central	GO_REF:0000033
CDK2	Pig	cyclin binding	enables	IEA	UniProtKB:P24941 more ...	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	cyclin binding		ISO	Ccne1 (Rattus norvegicus) and Ccne2 (Rattus norvegicus)	9068941		RGD	PMID:15809057 and REF_RGD_ID:1582338
CDK2	Pig	cyclin-dependent protein kinase activity	enables	IEA	UniProtKB:P24941 more ...	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	cyclin-dependent protein serine/threonine kinase activity		ISO	Cdk2 (Rattus norvegicus)	9068941		RGD	PMID:11823715 and REF_RGD_ID:70277
CDK2	Pig	cyclin-dependent protein serine/threonine kinase activity	enables	IEA	UniProtKB:P24941 more ...	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	cyclin-dependent protein serine/threonine kinase activity	enables	IBA	CGD:CAL0000191263 more ...	150520179		GO_Central	GO_REF:0000033
CDK2	Pig	histone kinase activity	contributes_to	IEA	UniProtKB:P24941 and ensembl:ENSP00000266970	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	kinase activity	enables	IEA	UniProtKB:P97377 and ensembl:ENSMUSP00000026415	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	kinase activity	enables	IEA	UniProtKB-KW:KW-0418	150520179		UniProt	GO_REF:0000043
CDK2	Pig	magnesium ion binding	enables	IEA	UniProtKB:P97377 and ensembl:ENSMUSP00000026415	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	nucleotide binding	enables	IEA	UniProtKB-KW:KW-0547	150520179		UniProt	GO_REF:0000043
CDK2	Pig	nucleotide binding	enables	IEA	UniRule:UR001503341	150520179		UniProt	GO_REF:0000104
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P03129	9068941	PMID:16061792 and PMID:22810586	IntAct	PMID:16061792 and PMID:22810586
CDK2	Pig	protein binding	enables	ISO	PR:Q5IBH7	9068941	PMID:28031483	MGI	PMID:28031483
CDK2	Pig	protein binding	enables	ISO	PR:P46414	9068941	PMID:8033213	MGI	PMID:8033213
CDK2	Pig	protein binding	enables	ISO	PR:P39689	9068941	PMID:12124778	MGI	PMID:12124778
CDK2	Pig	protein binding	enables	ISO	UniProtKB:Q61457	9068941	PMID:20150892	IntAct	PMID:20150892
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P39689 and UniProtKB:P46414	9068941	PMID:24380855	BHF-UCL	PMID:24380855
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P51943 and UniProtKB:Q61457	9068941	PMID:19592082	IntAct	PMID:19592082
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P53566	9068941	PMID:15107404	UniProt	PMID:15107404
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P24385	9068941	PMID:34591642	IntAct	PMID:34591642
CDK2	Pig	protein binding	enables	ISO	UniProtKB:O96020 more ...	9068941	PMID:25852190	IntAct	PMID:25852190
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P24864 and UniProtKB:Q09472	9068941	PMID:10330164	IntAct	PMID:10330164
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P01112 more ...	9068941	PMID:32814053	IntAct	PMID:32814053
CDK2	Pig	protein binding	enables	ISO	UniProtKB:O95067 more ...	9068941	PMID:23455922	IntAct	PMID:23455922
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P50613	9068941	PMID:16327805	IntAct	PMID:16327805
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P50613 and UniProtKB:Q16667	9068941	PMID:15530371	IntAct	PMID:15530371
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P20248 and UniProtKB:P46527	9068941	PMID:17254966	IntAct	PMID:17254966
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P20248	9068941	PMID:12244298 more ...	IntAct	PMID:12244298 more ...
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P06400	9068941	PMID:20871633	IntAct	PMID:20871633
CDK2	Pig	protein binding	enables	ISO	UniProtKB:O96020 more ...	9068941	PMID:26496610	IntAct	PMID:26496610
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P20248 and UniProtKB:P24864	9068941	PMID:16431923	IntAct	PMID:16431923
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P38936 more ...	9068941	PMID:17698606	IntAct	PMID:17698606
CDK2	Pig	protein binding	enables	ISO	UniProtKB:Q969H0-4 and UniProtKB:Q9UBI4	9068941	PMID:23082202	IntAct	PMID:23082202
CDK2	Pig	protein binding	enables	ISO	UniProtKB:O96020 more ...	9068941	PMID:23602568	IntAct	PMID:23602568
CDK2	Pig	protein binding	enables	ISO	UniProtKB:O95067 more ...	9068941	PMID:24358021	IntAct	PMID:24358021
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P06400 more ...	9068941	PMID:8756624	IntAct	PMID:8756624
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P38936 and UniProtKB:Q16667	9068941	PMID:24218572	IntAct	PMID:24218572
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P24864	9068941	PMID:19470470 more ...	IntAct	PMID:19470470 more ...
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P38936 and UniProtKB:P46527	9068941	PMID:17418410 and PMID:25241761	IntAct	PMID:17418410 and PMID:25241761
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P51946	9068941	PMID:8521818	IntAct	PMID:8521818
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P38936	9068941	PMID:16765349 more ...	IntAct	PMID:16765349 more ...
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P33552 and UniProtKB:P61024	9068941	PMID:2227411	GO_Central	PMID:2227411
CDK2	Pig	protein binding	enables	ISO	UniProtKB:Q16667	9068941	PMID:11463386 and PMID:8242750	UniProt	PMID:11463386 and PMID:8242750
CDK2	Pig	protein binding	enables	ISO	UniProtKB:O95067 more ...	9068941	PMID:15232106	IntAct	PMID:15232106
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P20248 more ...	9068941	PMID:15890360	IntAct	PMID:15890360
CDK2	Pig	protein binding	enables	ISO	UniProtKB:Q5IBH7 and UniProtKB:Q5MJ68	9068941	PMID:15611625	UniProt	PMID:15611625
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P24864 and UniProtKB:P46527	9068941	PMID:17254967	IntAct	PMID:17254967
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P46527	9068941	PMID:16326706 more ...	IntAct	PMID:16326706 more ...
CDK2	Pig	protein binding	enables	ISO	UniProtKB:Q86T82	9068941	PMID:21596315	UniProt	PMID:21596315
CDK2	Pig	protein binding	enables	ISO	UniProtKB:O95835	9068941	PMID:25218637	IntAct	PMID:25218637
CDK2	Pig	protein binding	enables	ISO	UniProtKB:O75179	9068941	PMID:19150984	UniProt	PMID:19150984
CDK2	Pig	protein binding	enables	ISO	UniProtKB:Q86Y37	9068941	PMID:19829063	UniProt	PMID:19829063
CDK2	Pig	protein binding	enables	ISO	UniProtKB:Q5MJ70	9068941	PMID:11980914 more ...	UniProt	PMID:11980914 more ...
CDK2	Pig	protein binding	enables	ISO	UniProtKB:Q9JHD1	9068941	PMID:19773423	UniProt	PMID:19773423
CDK2	Pig	protein binding	enables	ISO	UniProtKB:O95067 more ...	9068941	PMID:33961781	IntAct	PMID:33961781
CDK2	Pig	protein binding	enables	ISO	UniProtKB:O95067 more ...	9068941	PMID:28514442	IntAct	PMID:28514442
CDK2	Pig	protein binding	enables	ISO	UniProtKB:O96020 more ...	9068941	PMID:9840943	IntAct	PMID:9840943
CDK2	Pig	protein binding	enables	ISO	UniProtKB:O96020 more ...	9068941	PMID:35271311	IntAct	PMID:35271311
CDK2	Pig	protein binding	enables	ISO	UniProtKB:Q9Y6K9	9068941	PMID:20098747	IntAct	PMID:20098747
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P51943	9068941	PMID:21565702	IntAct	PMID:21565702
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P30274	9068941	PMID:22940584	IntAct	PMID:22940584
CDK2	Pig	protein binding	enables	ISO	UniProtKB:Q96PU4	9068941	PMID:15178429 and PMID:21952639	IntAct	PMID:15178429 and PMID:21952639
CDK2	Pig	protein binding	enables	ISO	PR:P17918 more ...	9068941	PMID:12970760	MGI	PMID:12970760
CDK2	Pig	protein binding	enables	ISO	UniProtKB:O75956	9068941	PMID:23781148	UniProt	PMID:23781148
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P61024	9068941	PMID:29997244 more ...	IntAct	PMID:29997244 more ...
CDK2	Pig	protein binding	enables	ISO	UniProtKB:P49715	9068941	PMID:15107404	UniProt	PMID:15107404
CDK2	Pig	protein binding	enables	ISO	UniProtKB:O43303	9068941	PMID:12361598	HGNC-UCL	PMID:12361598
CDK2	Pig	protein domain specific binding	enables	IEA	UniProtKB:P24941 and ensembl:ENSP00000266970	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	protein kinase activity	enables	IEA	InterPro:IPR000719 and InterPro:IPR008271	150520179		InterPro	GO_REF:0000002
CDK2	Pig	protein kinase activity	enables	IEA	UniProtKB:P97377 and ensembl:ENSMUSP00000026415	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	protein serine/threonine kinase activity	enables	IEA	UniProtKB-KW:KW-0723	150520179		UniProt	GO_REF:0000043
CDK2	Pig	protein serine/threonine kinase activity	enables	IEA	UniProtKB:P24941 more ...	150520179		Ensembl	GO_REF:0000107
CDK2	Pig	protein-containing complex binding		ISO	Ccne1 (Rattus norvegicus) more ...	9068941		RGD	PMID:10952244 and REF_RGD_ID:2289341
CDK2	Pig	transferase activity	enables	IEA	UniProtKB-KW:KW-0808	150520179		UniProt	GO_REF:0000043

RGD Manual Annotations

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CDK2	Pig	G1/S transition pathway		ISO	CDK2 (Homo sapiens)	9068941		RGD	PMID:10919634 more ...

Imported Annotations - PID (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CDK2	Pig	interleukin-2 signaling pathway		ISO	CDK2 (Homo sapiens)	9068941		PID	PID:200098
CDK2	Pig	mTOR signaling pathway		ISO	CDK2 (Homo sapiens)	9068941		PID	PID:200096
CDK2	Pig	p53 signaling pathway		ISO	CDK2 (Homo sapiens)	9068941		PID	PID:200206

PMID:14681463	PMID:15750306	PMID:22301074	PMID:23836398	PMID:27307074	PMID:30032202	PMID:35189966

CDK2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	21,365,764 - 21,372,168 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	21,365,723 - 21,372,170 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	22,941,174 - 22,947,591 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CDK2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	55,966,830 - 55,972,789 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	55,966,781 - 55,972,789 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	56,360,614 - 56,366,573 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	54,646,826 - 54,652,835 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	54,646,825 - 54,652,834	NCBI
Celera	12	56,013,264 - 56,019,276 (+)	NCBI		Celera
Cytogenetic Map	12	q13.2	NCBI
HuRef	12	53,399,466 - 53,405,479 (+)	NCBI		HuRef
CHM1_1	12	56,327,689 - 56,333,679 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	55,933,893 - 55,939,852 (+)	NCBI		T2T-CHM13v2.0

Cdk2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	128,533,807 - 128,540,920 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	128,533,808 - 128,540,900 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	128,697,938 - 128,705,051 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	128,697,939 - 128,705,031 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	128,134,995 - 128,142,107 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	128,100,888 - 128,107,961 (-)	NCBI		MGSCv36	mm8
Celera	10	131,090,071 - 131,097,183 (-)	NCBI		Celera
Cytogenetic Map	10	D3	NCBI
cM Map	10	77.13	NCBI

Cdk2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	1,714,392 - 1,721,964 (-)	NCBI		GRCr8
mRatBN7.2	7	1,129,878 - 1,137,431 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	1,129,811 - 1,137,403 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	3,893,030 - 3,900,519 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	5,768,702 - 5,776,191 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	6,065,517 - 6,073,007 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	3,124,953 - 3,132,533 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	3,124,954 - 3,132,457 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	3,097,653 - 3,105,210 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	2,000,196 - 2,007,682 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	2,000,196 - 2,007,682 (-)	NCBI
Celera	7	1,000,083 - 1,007,560 (-)	NCBI		Celera
Cytogenetic Map	7	q11	NCBI

Cdk2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955458	3,555,603 - 3,562,120 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955458	3,555,603 - 3,561,063 (+)	NCBI	ChiLan1.0	ChiLan1.0

CDK2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	38,356,902 - 38,362,969 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	38,353,674 - 38,359,695 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	32,940,225 - 32,946,236 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	33,189,934 - 33,195,945 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	33,189,934 - 33,195,945 (-)	Ensembl	panpan1.1		panPan2

CDK2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	300,863 - 306,546 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	300,903 - 305,438 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	362,779 - 368,479 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	307,657 - 313,366 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	307,694 - 312,540 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	285,465 - 291,170 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	528,243 - 533,942 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	652,514 - 658,220 (+)	NCBI		UU_Cfam_GSD_1.0

Cdk2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	58,484,370 - 58,490,389 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936646	379,842 - 385,877 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936646	379,849 - 385,648 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CDK2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	51,905,085 - 51,910,209 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	51,905,115 - 51,909,907 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	194,076,082 - 194,082,105 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cdk2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624802	12,076,443 - 12,082,630 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624802	12,076,443 - 12,082,608 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in CDK2
107 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	NM_001285465	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003126260	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005655594	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000033	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK231451	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK238749	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK351432	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK395994	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU457395	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01106379	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JX967576	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000000398 ⟹ ENSSSCP00000000392

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	5	21,365,764 - 21,372,167 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000053267 ⟹ ENSSSCP00000053609

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	5	21,366,552 - 21,372,163 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000057759 ⟹ ENSSSCP00000048647

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	5	21,365,968 - 21,372,168 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000081653 ⟹ ENSSSCP00000067529

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	5	21,365,775 - 21,372,160 (+)	Ensembl

RefSeq Acc Id:

NM_001285465 ⟹ NP_001272394

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	5	21,365,830 - 21,372,003 (+)	NCBI

Sequence:

show sequence

CTGCGTTCCATCCCGACCTGGGGCCGCCGTGCAGGGCCCTGTTTCCCCCTCCTCGGCCCCCGAGAGCTGGGTGCCGCTTTCTGCTGGGTTCCCAGGCCCCCGCTCCAGGGCCGGGCTGATTCGACTCG
CTAGCGCTTCATGGAGAACTTCCAAAAAGTGGAAAAGATCGGAGAGGGCACGTACGGAGTTGTGTACAAAGCCAAAAACAAGGTGACGGGAGAAGTGGTGGCGCTTAAAAAAATCCGCCTGGACACTG
AGACGGAGGGTGTACCCAGTACTGCCATTCGAGAGATCTCTCTGCTTAAGGAGCTTAACCACCCTAATATTGTCAAGTTGCTGGATGTCATTCACACAGAAAACAAACTCTACCTGGTTTTTGAGTTT
CTGCACCAGGATCTCAAGAAATTCATGGATGCCTCTGCTCTCACTGGCATTCCTCTTCCCCTCATAAAGAGTTATCTGTTCCAGCTGCTTCAGGGGCTAGCTTTTTGCCATTCTCATCGGGTCTTGCA
CCGAGACCTTAAACCTCAGAATCTGCTTATCAACGCAGAAGGATCTATCAAGTTAGCAGACTTTGGACTGGCCAGAGCCTTTGGAGTCCCTGTTCGTACATACACCCATGAGGTGGTGACTTTGTGGT
ACAGAGCACCTGAAATCCTTCTGGGCTGCAAATACTACTCTACAGCCGTGGACATCTGGAGCCTGGGCTGCATCTTTGCTGAGATGGTGACCCGCCGGGCTCTGTTCCCTGGAGATTCTGAGATTGAC
CAGCTCTTCCGGATCTTTCGGACTCTCGGGACCCCAGATGAGGTGGTTTGGCCAGGAGTTACTTCCATGCCTGATTATAAACCGAGTTTCCCTAAGTGGGCCAGGCAAGATTTTAGCAAAGTTGTGCC
TCCCCTGGATGAAGATGGACGGAGCTTGTTATCGCAAATGCTGCACTACGACCCCAACAAGCGGATTTCAGCAAAGGCAGCTCTGGCTCACCCTTTCTTCCAGGATGTGACCAAGCCAGTACCTCACC
TTCGACTTTGATGGCCTTTGTGAACCCTACCCCTCGTCTCACCCTCTCCTCCAGTGGGGGCCTGATCTGGCTTGGCCCAGGGCTTTTAGCCCACTGTTCTTGTCTGGCTGCCTTAGCACTCACCTGCT
CCTCTCAGCCAGCCAACTTTGGAGAAACAGGGGGTAGAGGGGAGCAATAGGTGAAATTGAAAGGAAGCTTCAGTACTAGATGCACTTAAGTCAGCCTCCACCACCCTCCCCCCCTCCTCTTAGTCGTT
ACTTATGAGAGCTGGTATTTAAAAAAAACAAAAAAAAAGACTGACTCTTTCTCCTCCCACCACACAGGGATTGCCATCCAGTCTCTGAAAGCCCAGAAATTATTTTCTGTGTTTGGGAGACCCCAAAT
CTCCTGCAGCCATTGCGTAAAGCTAACTGATAACAGCGGGGCTAAGTTGGAACTTTTGAAACCCAAGCAAAACAGAAACATAGGGAGGGACCTGTTTTAAAGAATTAGGTTAAAAAAATAGATCCAAC
CAGTTTATGCCCTAGTTGTAGTGTTTCATCTCACCTAACAGTCTGGGAGATTCAAGACTCCCAGTCTCTGCGGTGCTAGTGAGGCGGCAGTAGAAATGGTTGCTCCTAGTCTTCTTGCCTGTCCCTCC
TACAGGCAAGAGGTGTCTGGGACGCTCTGGGACAAAGACAATGCTTCACTGAGGCCTTAAGAGGCAAGTGAAAAATGTTTGAATTTTTCTCTTCCTTTTAAGAGTCTTAGTTCATCAGGTGCTAAGTC
CTATCTTCCTCTGAAGGCCACCCTCATAAGAGTGAAAGTTAAGGTTTAGACATCGTTTTGAGAATGCTGACACTTTTTTAGGGCTGTGACTGAGTGGGGGCGTTGGGGAAAAAATATTTCTTTAAAAG
AAGGATGAACAATTATATTTATATTTCAGGTTATAGTAGTTTTTTAAGTGGGAATGGGTGGATTTGTTGCC

hide sequence

RefSeq Acc Id:

XM_003126260 ⟹ XP_003126308

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	5	21,365,763 - 21,372,170 (+)	NCBI

Sequence:

show sequence

GGGAACTGGCGGGGGGAGGCGGCAACATTGTTTCAAGTTGGACAAATTGACAAGAGCGAGAGATACGCTGCGTTCCATCCCGACCTGGGGCTGCCGTGCAGGGCCCTGTTTCCCCCTCCTCGGCCCCC
GAGAGCTGGGTGCCGCTTTCTGCTGGGTTCCCAGGCCCCCGCTCCAGGGCCGGGCTGATTCGACTCGCTAGCGCTTCATGGAGAACTTCCAAAAAGTGGAAAAGATCGGAGAGGGCACGTACGGAGTT
GTGTACAAAGCCAAAAACAAGGTGACGGGAGAAGTGGTGGCGCTTAAAAAAATCCGCCTGGACACTGAGACGGAGGGTGTACCCAGTACTGCCATTCGAGAGATCTCTCTGCTTAAGGAGCTTAACCA
CCCTAATATTGTCAAGTTGCTGGATGTCATTCACACAGAAAACAAACTCTACCTGGTTTTTGAGTTTCTGCACCAGGATCTCAAGAAATTCATGGATGCCTCTGCTCTCACTGGCATTCCTCTTCCCC
TCATAAAGAGTTATCTGTTCCAGCTGCTTCAGGGGCTAGCTTTTTGCCATTCTCATCGGGTCTTGCACCGAGACCTTAAACCTCAGAATCTGCTTATCAACGCAGAAGGATCTATCAAGTTAGCAGAC
TTTGGACTGGCCAGAGCCTTTGGAGTCCCTGTTCGTACATACACCCATGAGGTGACCCGCCGGGCTCTGTTCCCTGGAGATTCTGAGATTGACCAGCTCTTCCGGATCTTTCGGACTCTTGGGACCCC
AGATGAGGTGGTTTGGCCAGGAGTTACTTCCATGCCTGATTATAAACCGAGTTTCCCTAAGTGGGCCAGGCAAGATTTTAGCAAAGTTGTGCCTCCCCTGGATGAAGATGGACGGAGCTTGTTATCGC
AAATGCTGCACTACGACCCCAACAAGCGGATTTCAGCAAAGGCAGCTCTGGCTCACCCTTTCTTCCAGGATGTGACCAAGCCAGTACCTCACCTTCGACTTTGATGGCCTTTGTGAACCCTACCCCTC
GTCTCACCCTCTCCTCCAGTGGGGGCCTGATCTGGCTTGGCCCAGGGCTTTTAGCCCACTGTTCTTGTCTGGCTGCCTTAGCACTCACCTGCTCCTCTCAGCCAGCCAACTTTGGAGAAACAGGGGGT
AGAGGGGAGCAATAGGTGAAATTGAAAGGAAGCTTCAGTATTAGATGCACTTAAGTCAGCCTCCACCACCCTCCCCCCCTCCTCTTAGTCGTTACTTATGAGAGCTGGTATTTAAAAAAAACAAAAAA
AAAGACTGACTCTTTCTCCTCCCACCACACAGGGATTGCCATCCAGTCTCTGAAAGCCCAGAAATTATTTTCTGTGTTTGGGAGACCCCAAATCTCCTGCAGCCATTGCGTAAAGCTAACTGATAACA
GCGGGGCTAAGTTGGAACTTTTGAAACCCAAGCAAAACAGAAACATAGGGAGGGACCTGTTTTAAAGAATTAGGTTAAAAAAATAGATCCAACCAGTTTATGCCCTAGTTGTAGTGTTTCATCTCACC
TAACAGTCTGGGAGATTCAAGACTCCCAGTCTCTGCGGTGCTAGTGAGGCGGCAGTAGAAATGGTTGCTCCTAGTCTTCTTGCCTGTCCCTCCTACAGGCAAGAGGTGTCTGGGAGGCTCTGGGACAA
AGACAATGCTTCACTGAGGCCTTAAGAGGCAAGTGAAAAATGTTTGAATTTTTCTCTTCCTTTTAAGAGTCTTAGTTCATCAGGTGCTAAGTCCTATCTTCCTCTGAAGGCCACCCTCATAAGAGTGA
AAGTTAAGGTTTAGACATCGTTTTGAGAATGCTGACACTTTTTTAGGGCTGTGACTGAGTGGGGGCATTGGGGAAAAAATATTTCTTTAAAAGAAGGATGAACAATTATATTTATATTTCAGGTTATA
GTAGTTTTTTAAGTGGGAATGGGTGGATTTGTTGCCCTGTGCACCTTGGGGTTTATAATGCAAATGTTTTTAAAAAATTTTTTTTTCTTTTTATGATTTTGTCTCTTTCCTCCAACCTTTTGTCCTTG
AGTGTTCTTGCTGTTAACATTATTTGTAATTTAGTTTATAATTCATTAAAAAAAAGTTCTTAGTTTTATAGCTCA

hide sequence

RefSeq Acc Id:

XM_005655594 ⟹ XP_005655651

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	5	21,365,723 - 21,372,170 (+)	NCBI

Sequence:

show sequence

GGAAACGCGGGAAGGAGGGGCGGGGCTTCTGGTGGCGGTAGGGAACTGGCGGGGGGAGGCGGCAACATTGTTTCAAGTTGGACAAATTGACAAGAGCGAGAGATACGCTGCGTTCCATCCCGACCTGG
GGCTGCCGTGCAGGGCCCTGTTTCCCCCTCCTCGGCCCCCGAGAGCTGGGTGCCGCTTTCTGCTGGGTTCCCAGGCCCCCGCTCCAGGGCCGGGCTGATTCGACTCGCTAGCGCTTCATGGAGAACTT
CCAAAAAGTGGAAAAGATCGGAGAGGGCACGTACGGAGTTGTGTACAAAGCCAAAAACAAGGTGACGGGAGAAGTGGTGGCGCTTAAAAAAATCCGCCTGGACACTGAGACGGAGGGTGTACCCAGTA
CTGCCATTCGAGAGATCTCTCTGCTTAAGGAGCTTAACCACCCTAATATTGTCAAGTTGCTGGATGTCATTCACACAGAAAACAAACTCTACCTGGTTTTTGAGTTTCTGCACCAGGATCTCAAGAAA
TTCATGGATGCCTCTGCTCTCACTGGCATTCCTCTTCCCCTCATAAAGAGTTATCTGTTCCAGCTGCTTCAGGGGCTAGCTTTTTGCCATTCTCATCGGGTCTTGCACCGAGACCTTAAACCTCAGAA
TCTGCTTATCAACGCAGAAGGATCTATCAAGTTAGCAGACTTTGGACTGGCCAGAGCCTTTGGAGTCCCTGTTCGTACATACACCCATGAGGTGGTGACTTTGTGGTACAGAGCACCTGAAATCCTTC
TGGGCTGCAAATACTACTCTACAGCCGTGGACATCTGGAGCCTGGGCTGCATCTTTGCTGAGATGCACCTAGTATGTACCCAGCACCATGCTAGGTGCTGTGGGGAACACAGAAGAAATGGAAGACAC
AGTCTCTGCCCGCTGTGCTCCTATCTAGAAGTGGCTGCATCACAAGGAGGGGGGATGACCGCAGTGTCTACCCCACACCCCGTGACCCGCCGGGCTCTGTTCCCTGGAGATTCTGAGATTGACCAGCT
CTTCCGGATCTTTCGGACTCTTGGGACCCCAGATGAGGTGGTTTGGCCAGGAGTTACTTCCATGCCTGATTATAAACCGAGTTTCCCTAAGTGGGCCAGGCAAGATTTTAGCAAAGTTGTGCCTCCCC
TGGATGAAGATGGACGGAGCTTGTTATCGCAAATGCTGCACTACGACCCCAACAAGCGGATTTCAGCAAAGGCAGCTCTGGCTCACCCTTTCTTCCAGGATGTGACCAAGCCAGTACCTCACCTTCGA
CTTTGATGGCCTTTGTGAACCCTACCCCTCGTCTCACCCTCTCCTCCAGTGGGGGCCTGATCTGGCTTGGCCCAGGGCTTTTAGCCCACTGTTCTTGTCTGGCTGCCTTAGCACTCACCTGCTCCTCT
CAGCCAGCCAACTTTGGAGAAACAGGGGGTAGAGGGGAGCAATAGGTGAAATTGAAAGGAAGCTTCAGTATTAGATGCACTTAAGTCAGCCTCCACCACCCTCCCCCCCTCCTCTTAGTCGTTACTTA
TGAGAGCTGGTATTTAAAAAAAACAAAAAAAAAGACTGACTCTTTCTCCTCCCACCACACAGGGATTGCCATCCAGTCTCTGAAAGCCCAGAAATTATTTTCTGTGTTTGGGAGACCCCAAATCTCCT
GCAGCCATTGCGTAAAGCTAACTGATAACAGCGGGGCTAAGTTGGAACTTTTGAAACCCAAGCAAAACAGAAACATAGGGAGGGACCTGTTTTAAAGAATTAGGTTAAAAAAATAGATCCAACCAGTT
TATGCCCTAGTTGTAGTGTTTCATCTCACCTAACAGTCTGGGAGATTCAAGACTCCCAGTCTCTGCGGTGCTAGTGAGGCGGCAGTAGAAATGGTTGCTCCTAGTCTTCTTGCCTGTCCCTCCTACAG
GCAAGAGGTGTCTGGGAGGCTCTGGGACAAAGACAATGCTTCACTGAGGCCTTAAGAGGCAAGTGAAAAATGTTTGAATTTTTCTCTTCCTTTTAAGAGTCTTAGTTCATCAGGTGCTAAGTCCTATC
TTCCTCTGAAGGCCACCCTCATAAGAGTGAAAGTTAAGGTTTAGACATCGTTTTGAGAATGCTGACACTTTTTTAGGGCTGTGACTGAGTGGGGGCATTGGGGAAAAAATATTTCTTTAAAAGAAGGA
TGAACAATTATATTTATATTTCAGGTTATAGTAGTTTTTTAAGTGGGAATGGGTGGATTTGTTGCCCTGTGCACCTTGGGGTTTATAATGCAAATGTTTTTAAAAAATTTTTTTTTCTTTTTATGATT
TTGTCTCTTTCCTCCAACCTTTTGTCCTTGAGTGTTCTTGCTGTTAACATTATTTGTAATTTAGTTTATAATTCATTAAAAAAAAGTTCTTAGTTTTATAGCTCA

hide sequence


Protein RefSeqs	NP_001272394	(Get FASTA)	NCBI Sequence Viewer
	XP_003126308	(Get FASTA)	NCBI Sequence Viewer
	XP_005655651	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AGR86101	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000000392
	ENSSSCP00000000392.3
	ENSSSCP00000048647.2
	ENSSSCP00000053609.3
	ENSSSCP00000067529
	ENSSSCP00000067529.1
	ENSSSCP00015031276.1
	ENSSSCP00015031402.1
	ENSSSCP00025024650.1
	ENSSSCP00025024717.1
	ENSSSCP00025024758.1
	ENSSSCP00025024990.1
	ENSSSCP00025025052.1
	ENSSSCP00030029177.1
	ENSSSCP00030029215.1
	ENSSSCP00030029225.1
	ENSSSCP00030029304.1
	ENSSSCP00030029309.1
	ENSSSCP00035011655.1
	ENSSSCP00035011659.1
	ENSSSCP00035011660.1
	ENSSSCP00035011664.1
	ENSSSCP00040001491.1
	ENSSSCP00040001494.1
	ENSSSCP00045043735.1
	ENSSSCP00045043802.1
	ENSSSCP00050045973.1
	ENSSSCP00050045975.1
	ENSSSCP00050045977.1
	ENSSSCP00050045995.1
	ENSSSCP00050045997.1
	ENSSSCP00055015796.1
	ENSSSCP00055015829.1
	ENSSSCP00055015946.1
	ENSSSCP00055015976.1
	ENSSSCP00060044152.1
	ENSSSCP00060044207.1
	ENSSSCP00065028934.1
	ENSSSCP00065028940.1
	ENSSSCP00070050998.1
	ENSSSCP00070051000.1
	ENSSSCP00070051001.1
	ENSSSCP00070051002.1

RefSeq Acc Id:	XP_005655651 ⟸ XM_005655594
- Peptide Label:	isoform X1
- UniProtKB:	A0A4X1W3W2 (UniProtKB/TrEMBL), A0A8D0IA69 (UniProtKB/TrEMBL), F1SPH6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MENFQKVEKIGEGTYGVVYKAKNKVTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDL KPQNLLINAEGSIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMHLVCTQHHARCCGEHRRNGRHSLCPLCSYLEVAASQGGGMTAVSTPHPVTRRALFPGDSE IDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL hide sequence

RefSeq Acc Id:	XP_003126308 ⟸ XM_003126260
- Peptide Label:	isoform X2
- UniProtKB:	A0A4X1W9B6 (UniProtKB/TrEMBL), A0A5G2QRI3 (UniProtKB/TrEMBL), A0A287AXP1 (UniProtKB/TrEMBL), A0A4X1W9S8 (UniProtKB/TrEMBL), A0A8D0INN3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MENFQKVEKIGEGTYGVVYKAKNKVTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDL KPQNLLINAEGSIKLADFGLARAFGVPVRTYTHEVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVT KPVPHLRL hide sequence

RefSeq Acc Id:

NP_001272394 ⟸ NM_001285465

- UniProtKB:

A0A4X1W9I0 (UniProtKB/TrEMBL), U3M3E7 (UniProtKB/TrEMBL), A0A8D1TR27 (UniProtKB/TrEMBL), A0A8D0IL21 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MENFQKVEKIGEGTYGVVYKAKNKVTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIV
KLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCI
FAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL

hide sequence

Ensembl Acc Id:

ENSSSCP00000067529 ⟸ ENSSSCT00000081653

Ensembl Acc Id:

ENSSSCP00000053609 ⟸ ENSSSCT00000053267

Protein Domains

Protein kinase

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000037597	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00015057806	UniProtKB/TrEMBL
	ENSSSCG00025042960	UniProtKB/TrEMBL
	ENSSSCG00030045669	UniProtKB/TrEMBL
	ENSSSCG00035022946	UniProtKB/TrEMBL
	ENSSSCG00040003601	UniProtKB/TrEMBL
	ENSSSCG00045036121	UniProtKB/TrEMBL
	ENSSSCG00050076236	UniProtKB/TrEMBL
	ENSSSCG00055010189	UniProtKB/TrEMBL
	ENSSSCG00060074046	UniProtKB/TrEMBL
	ENSSSCG00065048745	UniProtKB/TrEMBL
	ENSSSCG00070029769	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000000398	ENTREZGENE
	ENSSSCT00000000398.4	UniProtKB/TrEMBL
	ENSSSCT00000053267.3	UniProtKB/TrEMBL
	ENSSSCT00000057759.3	UniProtKB/TrEMBL
	ENSSSCT00000081653	ENTREZGENE
	ENSSSCT00000081653.2	UniProtKB/TrEMBL
	ENSSSCT00015077672.1	UniProtKB/TrEMBL
	ENSSSCT00015077912.1	UniProtKB/TrEMBL
	ENSSSCT00025058259.1	UniProtKB/TrEMBL
	ENSSSCT00025058396.1	UniProtKB/TrEMBL
	ENSSSCT00025058478.1	UniProtKB/TrEMBL
	ENSSSCT00025058944.1	UniProtKB/TrEMBL
	ENSSSCT00025059078.1	UniProtKB/TrEMBL
	ENSSSCT00030063736.1	UniProtKB/TrEMBL
	ENSSSCT00030063807.1	UniProtKB/TrEMBL
	ENSSSCT00030063828.1	UniProtKB/TrEMBL
	ENSSSCT00030064021.1	UniProtKB/TrEMBL
	ENSSSCT00030064040.1	UniProtKB/TrEMBL
	ENSSSCT00035030020.1	UniProtKB/TrEMBL
	ENSSSCT00035030027.1	UniProtKB/TrEMBL
	ENSSSCT00035030030.1	UniProtKB/TrEMBL
	ENSSSCT00035030040.1	UniProtKB/TrEMBL
	ENSSSCT00040004599.1	UniProtKB/TrEMBL
	ENSSSCT00040004606.1	UniProtKB/TrEMBL
	ENSSSCT00045062161.1	UniProtKB/TrEMBL
	ENSSSCT00045062245.1	UniProtKB/TrEMBL
	ENSSSCT00050104704.1	UniProtKB/TrEMBL
	ENSSSCT00050104709.1	UniProtKB/TrEMBL
	ENSSSCT00050104712.1	UniProtKB/TrEMBL
	ENSSSCT00050104739.1	UniProtKB/TrEMBL
	ENSSSCT00050104743.1	UniProtKB/TrEMBL
	ENSSSCT00055020021.1	UniProtKB/TrEMBL
	ENSSSCT00055020062.1	UniProtKB/TrEMBL
	ENSSSCT00055020198.1	UniProtKB/TrEMBL
	ENSSSCT00055020230.1	UniProtKB/TrEMBL
	ENSSSCT00060101640.1	UniProtKB/TrEMBL
	ENSSSCT00060101744.1	UniProtKB/TrEMBL
	ENSSSCT00065066704.1	UniProtKB/TrEMBL
	ENSSSCT00065066717.1	UniProtKB/TrEMBL
	ENSSSCT00070059853.1	UniProtKB/TrEMBL
	ENSSSCT00070059856.1	UniProtKB/TrEMBL
	ENSSSCT00070059857.1	UniProtKB/TrEMBL
	ENSSSCT00070059858.1	UniProtKB/TrEMBL
Gene3D-CATH	Phosphorylase Kinase, domain 1	UniProtKB/TrEMBL
	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	CDK	UniProtKB/TrEMBL
	Kinase-like_dom_sf	UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	Ser/Thr_kinase_AS	UniProtKB/TrEMBL
KEGG Report	ssc:100154715	UniProtKB/TrEMBL
NCBI Gene	CDK2	ENTREZGENE
PANTHER	CELL DIVISION PROTEIN KINASE	UniProtKB/TrEMBL
	CYCLIN-DEPENDENT KINASE 2	UniProtKB/TrEMBL
Pfam	Pkinase	UniProtKB/TrEMBL
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/TrEMBL
SMART	S_TKc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56112	UniProtKB/TrEMBL
UniProt	A0A287AXP1	ENTREZGENE, UniProtKB/TrEMBL
	A0A4X1W3W2	ENTREZGENE, UniProtKB/TrEMBL
	A0A4X1W9B6	ENTREZGENE, UniProtKB/TrEMBL
	A0A4X1W9I0	ENTREZGENE, UniProtKB/TrEMBL
	A0A4X1W9S8	ENTREZGENE, UniProtKB/TrEMBL
	A0A5G2QRI3	ENTREZGENE
	A0A8D0IA69	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0IL21	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0INN3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0U7Y3_PIG	UniProtKB/TrEMBL
	A0A8D0Z327_PIG	UniProtKB/TrEMBL
	A0A8D1TR27	ENTREZGENE, UniProtKB/TrEMBL
	F1SPH6	ENTREZGENE, UniProtKB/TrEMBL
	U3M3E7	ENTREZGENE
UniProt Secondary	A0A287BB95	UniProtKB/TrEMBL
	A0A5G2QRI3	UniProtKB/TrEMBL
	U3M3E7	UniProtKB/TrEMBL
VGNC ID	VGNC:111748	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - PID (archival)