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Gene: Avpr1a (arginine vasopressin receptor 1A) Rattus norvegicus
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Symbol: Avpr1a
Name: arginine vasopressin receptor 1A
Description: Exhibits V1A vasopressin receptor binding activity; peptide hormone binding activity; and vasopressin receptor activity. Involved in several processes, including cellular cation homeostasis; mating; and positive regulation of blood circulation. Localizes to the cytoplasmic vesicle and plasma membrane. Used to study acute kidney failure; brain edema; and myocardial infarction. Biomarker of hypertension and renovascular hypertension. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human AVPR1A (arginine vasopressin receptor 1A); PARTICIPATES IN G protein mediated signaling pathway via Galphaq family; vasopressin signaling pathway; vasopressin signaling pathway via receptor type 1; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: antidiuretic hormone receptor 1a; arginine vasopressin receptor V1a; AVPR; MGC108538; V1a; V1aR; vascular/hepatic-type arginine vasopressin receptor; Vasopressin receptor V1a; vasopressin V1a receptor
Orthologs:
Homo sapiens (human) : AVPR1A (arginine vasopressin receptor 1A)  HGNC  Alliance
Mus musculus (house mouse) : Avpr1a (arginine vasopressin receptor 1A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Avpr1a (arginine vasopressin receptor 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : AVPR1A (arginine vasopressin receptor 1A)
Canis lupus familiaris (dog) : AVPR1A (arginine vasopressin receptor 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Avpr1a (arginine vasopressin receptor 1A)
Sus scrofa (pig) : AVPR1A (arginine vasopressin receptor 1A)
more info ...
Is Marker For: Strains:   SS.LEW-(D7Rat73-D7Rat128)/Ayd   LEW.SS-(D7Rat73-D7Rat128)/Ayd  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0767,341,366 - 67,345,290 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0767,528,358 - 67,532,282 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4762,225,537 - 62,229,461 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1762,246,266 - 62,250,191 (+)NCBI
Celera755,286,966 - 55,290,890 (+)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Avpr1a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2185
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.