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Gene: Avpr2 (arginine vasopressin receptor 2) Rattus norvegicus
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Symbol: Avpr2
Name: arginine vasopressin receptor 2
Description: Predicted to have vasopressin receptor activity. Involved in several processes, including negative regulation of renal sodium excretion; negative regulation of urine volume; and positive regulation of systemic arterial blood pressure. Predicted to localize to the integral component of plasma membrane. Used to study hypertension. Biomarker of ureteral obstruction. Human ortholog(s) of this gene implicated in nephrogenic diabetes insipidus. Orthologous to human AVPR2 (arginine vasopressin receptor 2); PARTICIPATES IN vasopressin signaling pathway; vasopressin signaling pathway via receptor type 2; G protein mediated signaling pathway via Galphas family; INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; bis(2-ethylhexyl) phthalate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: antidiuretic hormone receptor; AVPR V2; renal-type arginine vasopressin receptor; V2R; vasopressin receptor V2; vasopressin V2 receptor
Orthologs:
Homo sapiens (human) : AVPR2 (arginine vasopressin receptor 2)  HGNC  Alliance
Mus musculus (house mouse) : Avpr2 (arginine vasopressin receptor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Avpr2 (arginine vasopressin receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : AVPR2 (arginine vasopressin receptor 2)
Canis lupus familiaris (dog) : AVPR2 (arginine vasopressin receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Avpr2 (arginine vasopressin receptor 2)
Sus scrofa (pig) : AVPR2 (arginine vasopressin receptor 2)
more info ...
Allele / Splice: Avpr2em4Mcwi   Avpr2em5Mcwi  
Genetic Models: SS-Avpr2em4Mcwi SS-Avpr2em5Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X156,889,006 - 156,892,707 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01152,637,074 - 152,640,726 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X159,821,860 - 159,823,488 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X159,897,295 - 159,898,924 (+)NCBI
Celera1136,256,506 - 136,258,135 (-)NCBICelera
Cytogenetic MapXq37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Avpr2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2186
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.