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Gene: Cckar (cholecystokinin A receptor) Rattus norvegicus
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Symbol: Cckar
Name: cholecystokinin A receptor
Description: Exhibits cholecystokinin receptor activity. Involved in several processes, including positive regulation of somatostatin secretion; reduction of food intake in response to dietary excess; and regulation of metal ion transport. Localizes to the cytoplasm; plasma membrane; and terminal bouton. Used to study obesity and type 2 diabetes mellitus. Biomarker of pancreatic cancer. Human ortholog(s) of this gene implicated in obesity. Orthologous to human CCKAR (cholecystokinin A receptor); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CCK-A receptor; Cck-ar; CCK1-R; cholecystokinin receptor type A; cholecystokinin-1 receptor
Orthologs:
Homo sapiens (human) : CCKAR (cholecystokinin A receptor)  HGNC  Alliance
Mus musculus (house mouse) : Cckar (cholecystokinin A receptor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cckar (cholecystokinin A receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : CCKAR (cholecystokinin A receptor)
Canis lupus familiaris (dog) : CCKAR (cholecystokinin A receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cckar (cholecystokinin A receptor)
Sus scrofa (pig) : CCKAR (cholecystokinin A receptor)
more info ...
Is Marker For: QTLs:   Niddm28  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01459,610,939 - 59,619,786 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01459,691,504 - 59,747,723 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41462,052,510 - 62,057,201 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11462,054,843 - 62,064,735 (+)NCBI
Celera1456,400,364 - 56,408,663 (+)NCBICelera
Cytogenetic Map14q11NCBI
RH 3.4 Map14455.67RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cckar
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2289
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.