Alcrsp27 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Alcrsp27 (Alcohol response QTL 27) Rattus norvegicus

Symbol: Alcrsp27
Name: Alcohol response QTL 27
RGD ID: 2317879
Previously known as: LORR
Trait: response to alcohol trait   (VT:0010489)    
Measurement Type: duration of loss of righting reflex   (CMO:0002289)    
LOD Score: 3.3
P Value: 0.63
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81460,854,936 - 105,854,936RGD_MAPPER_PIPELINE
mRatBN7.21456,631,369 - 101,631,369RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01461,993,178 - 106,993,178RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01462,674,474 - 107,674,474RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41462,384,564 - 107,384,564RGD_MAPPER_PIPELINERGSC3.4
Cross Type: intercross
Strains Crossed: AT ANT 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alcrsp27Ratalcohol-induced mental disorder  IAGP 2317807 RGD 
Alcrsp27RatAtaxia  IAGP 2317807alcoholRGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alcrsp27Ratabnormal motor coordination/balance  IDA 2317807alcoholRGD 
Alcrsp27Ratalcohol preference  IDA 2317807 RGD 
Alcrsp27Ratimpaired righting response  IDA 2317807alcoholRGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alcrsp27Ratduration of loss of righting reflex  IDA 2317807 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alcrsp27Ratethanol  IDA 2317807 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alcrsp27Ratmoving tilting plane test  IDA 2317807 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alcrsp27RatANT  IEA 2317807 RGD 
Alcrsp27RatAT  IEA 2317807 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alcrsp27Ratresponse to alcohol trait  IDA 2317807 RGD 


#
Reference Title
Reference Citation
1. A major QTL for acute ethanol sensitivity in the alcohol tolerant and non-tolerant selected rat lines. Radcliffe RA, etal., Genes Brain Behav. 2009 May 25.


1 to 20 of 537 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
41217372Cfl1-ps6cofilin 1, pseudogene 6145674964356750117Rat
1304641Stim2stromal interaction molecule 2145687842857004405Rat
41116190LOC120096843U2 spliceosomal RNA145695727456957478Rat
1304958Tbc1d19TBC1 domain family, member 19145708430557200221Rat
2289Cckarcholecystokinin A receptor145729239757300747Rat
7543920LOC102552214uncharacterized LOC102552214145732206057326658Rat
1593096Rbpjrecombination signal binding protein for immunoglobulin kappa J region145733849357523330Rat
2320504LOC10036125960S ribosomal protein L13-like145763235857633066Rat
1565192Smim20small integral membrane protein 20145771130457722681Rat
1562860Sel1l3SEL1L family member 3145777551557882076Rat
620889Slc34a2solute carrier family 34 member 2145791093157930236Rat
41233465LOC120096615uncharacterized LOC120096615145793043557947798Rat
2320358Eif4e2-ps1eukaryotic translation initiation factor 4E family member 2, pseudogene 1145807814558079340Rat
1306572Anapc4anaphase promoting complex subunit 4145812599558159253Rat
1311414Zcchc4zinc finger CCHC-type containing 4145816546758207071Rat
1359515Pi4k2bphosphatidylinositol 4-kinase type 2 beta145822179058248716Rat
1589491SepsecsSep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase145831148458341745Rat
7627395LOC102552822uncharacterized LOC102552822145834457958368002Rat
1310391Lgi2leucine-rich repeat LGI family, member 2145841596558443450Rat
9279922Rpsa-ps28ribosomal protein SA, pseudogene 28145846651958467175Rat

1 to 20 of 537 rows
1 to 20 of 716 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10102D14Mco2289147546949375469784Ratregion
10102D14Mco2289147546949375470354Ratregion
10102D14Mco2289147546975275469784Ratregion
10488D14Mgh8116147248920772489324Ratregion
10773D14Mit10264148205747182057735Ratregion
11086D14Mgh1105148068483380684938Ratregion
33965D14Mit15193148361068083610873Ratregion
34345D14Mgh2134147351328073513414Ratregion
34616D14Mit16137148082812980828266Ratregion
36299D14Rat20155148120475181204906Ratregion
36307D14Rat21131149119526891195399Ratregion
37230D14Rat64207146361897163619178Ratregion
37306DXRat46269149680326196803529Ratregion
37328D14Rat61238146448149264481734Ratregion
37426D14Rat62221146381613763816358Ratregion
36864D14Rat28141147262099372621134Ratregion
37098D14Rat26222146502676965026991Ratregion
37660D14Rat49163149174233591742498Ratregion
37788D14Rat37240147580672875806970Ratregion
37828D14Rat39246147250854172508789Ratregion
1 to 20 of 716 rows

Peak: (D14Rat92)
Rat AssemblyChrPosition (strand)Source
GRCr81483,354,854 - 83,355,018 (+)Marker Load Pipeline
mRatBN7.21479,131,287 - 79,131,451 (+)MAPPER
Rnor_6.01484,493,097 - 84,493,260NCBI
Rnor_5.01485,174,393 - 85,174,556UniSTS
RGSC_v3.41484,884,482 - 84,884,646RGD
RGSC_v3.41484,884,483 - 84,884,646UniSTS
RGSC_v3.11484,903,627 - 84,903,791RGD
Celera1478,041,601 - 78,041,764UniSTS
SHRSP x BN Map1442.8RGD
SHRSP x BN Map1442.8UniSTS


1 to 10 of 32 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143999825175582726Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)146875779683368335Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1456631369101631369Rat
4889951Bss92Bone structure and strength QTL 923.9tibia area (VT:1000281)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)148205747195876975Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141854133263541332Rat

1 to 10 of 32 rows


Note Type Note Reference
qtl_cross_type intercross  
qtl_general number of animals used: 1201 F2 rats; 598 males, 603 females 2317807
qtl_general measurement method: after alcohol administration (3.5g/kg dose of alcohol 15%w/v) in the 3rd week, animals were placed on their back and the time at when they no longer right themselves was recorded; the lapse time at which they could right themselves was taken as loss of righting reflex (LORR) 2317807
qtl_general software used: SPSS version 16.0; L/QTL for QTL mapping 2317807