Cc2d2a (coiled-coil and C2 domain containing 2A) - Rat Genome Database

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Gene: Cc2d2a (coiled-coil and C2 domain containing 2A) Rattus norvegicus
Analyze
Symbol: Cc2d2a
Name: coiled-coil and C2 domain containing 2A
RGD ID: 1561042
Description: Predicted to be involved in several processes, including animal organ development; cilium assembly; and protein localization to ciliary transition zone. Predicted to localize to MKS complex. Human ortholog(s) of this gene implicated in Joubert syndrome 9; Meckel syndrome 6; and intellectual disability. Orthologous to human CC2D2A (coiled-coil and C2 domain containing 2A); INTERACTS WITH bisphenol A; cisplatin; cobalt dichloride.
Type: protein-coding
RefSeq Status: MODEL
Also known as: coiled-coil and C2 domain-containing protein 2A; LOC498386; RGD1561042; similar to RIKEN cDNA 5730509K17 gene
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21467,349,004 - 67,435,883 (-)NCBI
Rnor_6.0 Ensembl1471,895,246 - 71,973,419 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01471,895,128 - 71,979,452 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01471,922,693 - 72,005,867 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41472,514,369 - 72,593,323 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1466,307,068 - 66,391,488 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:21725307   PMID:22179047   PMID:24947469   PMID:25807483   PMID:26982032  


Genomics

Comparative Map Data
Cc2d2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21467,349,004 - 67,435,883 (-)NCBI
Rnor_6.0 Ensembl1471,895,246 - 71,973,419 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01471,895,128 - 71,979,452 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01471,922,693 - 72,005,867 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41472,514,369 - 72,593,323 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1466,307,068 - 66,391,488 (-)NCBICelera
Cytogenetic Map14q21NCBI
CC2D2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl415,469,865 - 15,601,552 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl415,469,865 - 15,601,557 (+)EnsemblGRCh38hg38GRCh38
GRCh38415,468,660 - 15,601,557 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37415,471,489 - 15,603,180 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36415,080,760 - 15,212,278 (+)NCBINCBI36hg18NCBI36
Celera415,935,348 - 16,067,126 (+)NCBI
Cytogenetic Map4p15.32NCBI
HuRef414,821,757 - 14,953,476 (+)NCBIHuRef
CHM1_1415,469,435 - 15,601,127 (+)NCBICHM1_1
Cc2d2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39543,819,715 - 43,898,317 (+)NCBIGRCm39mm39
GRCm39 Ensembl543,819,688 - 43,898,314 (+)Ensembl
GRCm38543,662,374 - 43,740,975 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl543,662,346 - 43,740,972 (+)EnsemblGRCm38mm10GRCm38
MGSCv37544,053,683 - 44,132,211 (+)NCBIGRCm37mm9NCBIm37
MGSCv36543,950,692 - 44,029,220 (+)NCBImm8
Celera541,092,084 - 41,170,278 (+)NCBICelera
Cytogenetic Map5B3NCBI
Cc2d2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554808,400,284 - 8,514,736 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554808,404,239 - 8,514,792 (-)NCBIChiLan1.0ChiLan1.0
CC2D2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1415,204,326 - 15,345,522 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl415,204,326 - 15,349,281 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v049,904,237 - 10,047,440 (+)NCBIMhudiblu_PPA_v0panPan3
CC2D2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1364,731,165 - 64,867,743 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl364,731,171 - 64,867,547 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha367,248,532 - 67,385,092 (-)NCBI
ROS_Cfam_1.0365,209,994 - 65,346,653 (-)NCBI
UMICH_Zoey_3.1364,698,051 - 64,834,697 (-)NCBI
UNSW_CanFamBas_1.0364,902,221 - 65,038,884 (-)NCBI
UU_Cfam_GSD_1.0365,262,451 - 65,398,970 (-)NCBI
Cc2d2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528558,614,110 - 58,714,043 (-)NCBI
SpeTri2.0NW_00493647712,315,829 - 12,415,915 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CC2D2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl810,779,332 - 10,898,193 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1810,779,206 - 10,898,189 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2810,399,621 - 10,546,074 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CC2D2A
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12734,625,701 - 34,761,873 (-)NCBI
ChlSab1.1 Ensembl2734,625,105 - 34,761,745 (-)Ensembl
Cc2d2a
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475516,252,488 - 16,361,794 (-)NCBI

Position Markers
RH133977  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21467,359,029 - 67,359,229 (+)MAPPER
Rnor_6.01471,901,854 - 71,902,053NCBIRnor6.0
Rnor_5.01471,929,419 - 71,929,618UniSTSRnor5.0
RGSC_v3.41472,522,265 - 72,522,448UniSTSRGSC3.4
Celera1466,314,732 - 66,314,931UniSTS
Cytogenetic Map14q21UniSTS
AW531538  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21467,359,447 - 67,359,623 (+)MAPPER
Rnor_6.01471,902,272 - 71,902,447NCBIRnor6.0
Rnor_5.01471,929,837 - 71,930,012UniSTSRnor5.0
RGSC_v3.41472,522,667 - 72,522,842UniSTSRGSC3.4
Celera1466,315,150 - 66,315,325UniSTS
RH 3.4 Map14487.49UniSTS
Cytogenetic Map14q21UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14975643572854397Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1412680424106641756Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143259392686191589Rat
1300154Bp189Blood pressure QTL 1893.04arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)143316331673391571Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)144031561085315610Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)144031561085315610Rat
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)144031561085315610Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)144031561085315610Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)144163756980841518Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1442442731108833671Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1443910761105074364Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1451818462105074364Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1460980905105980905Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1460980905105980905Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)146187332388870994Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1461993178106993178Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1463548095108548095Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:125
Count of miRNA genes:97
Interacting mature miRNAs:99
Transcripts:ENSRNOT00000006968
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 4 8 72 23 30 11
Low 3 39 49 41 19 41 8 11 2 12 11 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003752738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003752739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006221784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006221785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006221786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006221787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACYVU010000254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000079895   ⟹   ENSRNOP00000074960
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1471,895,246 - 71,973,419 (-)Ensembl
RefSeq Acc Id: XM_003752738   ⟹   XP_003752786
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1466,307,068 - 66,391,488 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003752739   ⟹   XP_003752787
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1466,307,068 - 66,391,298 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006221784   ⟹   XP_006221846
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1466,307,068 - 66,391,488 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006221785   ⟹   XP_006221847
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1466,307,068 - 66,391,488 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006221786   ⟹   XP_006221848
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1466,307,068 - 66,391,488 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006221787   ⟹   XP_006221849
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1466,307,068 - 66,391,488 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008766201   ⟹   XP_008764423
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1466,307,068 - 66,382,036 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008766205   ⟹   XP_008764427
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1466,307,068 - 66,382,036 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599546   ⟹   XP_017455035
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01471,895,128 - 71,979,452 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017604803   ⟹   XP_017460292
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1466,307,068 - 66,391,488 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017604804   ⟹   XP_017460293
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1466,307,068 - 66,382,846 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017604805   ⟹   XP_017460294
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1466,307,068 - 66,380,317 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039092785   ⟹   XP_038948713
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21467,349,004 - 67,435,882 (-)NCBI
RefSeq Acc Id: XM_039092786   ⟹   XP_038948714
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21467,349,004 - 67,435,031 (-)NCBI
RefSeq Acc Id: XM_039092787   ⟹   XP_038948715
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21467,349,004 - 67,435,882 (-)NCBI
RefSeq Acc Id: XM_039092788   ⟹   XP_038948716
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21467,349,004 - 67,435,882 (-)NCBI
RefSeq Acc Id: XM_039092789   ⟹   XP_038948717
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21467,349,004 - 67,435,882 (-)NCBI
RefSeq Acc Id: XM_039092790   ⟹   XP_038948718
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21467,349,004 - 67,429,757 (-)NCBI
RefSeq Acc Id: XM_039092791   ⟹   XP_038948719
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21467,349,004 - 67,429,757 (-)NCBI
RefSeq Acc Id: XM_039092792   ⟹   XP_038948720
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21467,364,901 - 67,435,883 (-)NCBI
RefSeq Acc Id: XM_039092793   ⟹   XP_038948721
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21467,349,004 - 67,397,588 (-)NCBI
RefSeq Acc Id: XM_039092794   ⟹   XP_038948722
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21467,373,724 - 67,435,883 (-)NCBI
RefSeq Acc Id: XM_039092795   ⟹   XP_038948723
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21467,380,886 - 67,435,883 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_003752786   ⟸   XM_003752738
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_003752787   ⟸   XM_003752739
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006221849   ⟸   XM_006221787
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006221847   ⟸   XM_006221785
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006221848   ⟸   XM_006221786
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006221846   ⟸   XM_006221784
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008764427   ⟸   XM_008766205
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_008764423   ⟸   XM_008766201
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_017460292   ⟸   XM_017604803
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_017460293   ⟸   XM_017604804
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_017460294   ⟸   XM_017604805
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_017455035   ⟸   XM_017599546
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000074960   ⟸   ENSRNOT00000079895
RefSeq Acc Id: XP_038948716   ⟸   XM_039092788
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038948717   ⟸   XM_039092789
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038948715   ⟸   XM_039092787
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038948713   ⟸   XM_039092785
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038948714   ⟸   XM_039092786
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038948719   ⟸   XM_039092791
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038948718   ⟸   XM_039092790
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038948721   ⟸   XM_039092793
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038948720   ⟸   XM_039092792
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038948722   ⟸   XM_039092794
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038948723   ⟸   XM_039092795
- Peptide Label: isoform X9
Protein Domains
C2

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
14 71958977 71958978 C A snv WN/N (MCW), M520/N (MCW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561042 AgrOrtholog
Ensembl Genes ENSRNOG00000059715 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000074960 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000079895 UniProtKB/TrEMBL
InterPro C2_Ca-dep UniProtKB/TrEMBL
  CC2D2AN-C2 UniProtKB/TrEMBL
  DUF5523 UniProtKB/TrEMBL
NCBI Gene 498386 ENTREZGENE
Pfam CC2D2AN-C2 UniProtKB/TrEMBL
  DUF5523 UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
PhenoGen Cc2d2a PhenoGen
SMART SM00239 UniProtKB/TrEMBL
UniProt A0A0G2K9D9_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-25 Cc2d2a  coiled-coil and C2 domain containing 2A  RGD1561042  similar to RIKEN cDNA 5730509K17 gene  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1561042  similar to RIKEN cDNA 5730509K17 gene   RGD1561042_predicted  similar to RIKEN cDNA 5730509K17 gene (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561042_predicted  similar to RIKEN cDNA 5730509K17 gene (predicted)  LOC498386  similar to RIKEN cDNA 5730509K17 gene  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498386  similar to RIKEN cDNA 5730509K17 gene      Symbol and Name status set to provisional 70820 PROVISIONAL