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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,3,5-trinitro-1,3,5-triazinane | decreases expression | EXP | | 6480464 | cyclonite results in decreased expression of SLC35E4 mRNA | CTD | PMID:25559034 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:734095 | 6480464 | Tetrachlorodibenzodioxin affects the expression of SLC35E4 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SLC35E4 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1602959 | 6480464 | [Tetrachlorodibenzodioxin co-treated with 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide] results in decreased expression of SLC35E4 mRNA | CTD | PMID:29704546 | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | increases expression | ISO | RGD:1602959 | 6480464 | 2 more ... | CTD | PMID:26705709 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2, 4-dinitrotoluene affects the expression of SLC35E4 mRNA | CTD | PMID:21346803 | 2-hydroxypropanoic acid | decreases expression | ISO | RGD:1602959 | 6480464 | Lactic Acid results in decreased expression of SLC35E4 mRNA | CTD | PMID:30851411 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RGD:1602959 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of SLC35E4 mRNA more ... | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | RGD:1602959 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of SLC35E4 mRNA | CTD | PMID:28628672 | 4-hydroxyphenyl retinamide | decreases expression | ISO | RGD:734095 | 6480464 | Fenretinide results in decreased expression of SLC35E4 mRNA | CTD | PMID:28973697 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of SLC35E4 mRNA | CTD | PMID:31881176 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of SLC35E4 mRNA | CTD | PMID:16483693 | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of SLC35E4 mRNA | CTD | PMID:30779732 | aristolochic acid A | increases expression | ISO | RGD:1602959 | 6480464 | aristolochic acid I results in increased expression of SLC35E4 mRNA | CTD | PMID:33212167 | benzo[a]pyrene | increases methylation | ISO | RGD:1602959 | 6480464 | Benzo(a)pyrene results in increased methylation of SLC35E4 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | RGD:1602959 | 6480464 | Benzo(a)pyrene results in increased expression of SLC35E4 mRNA | CTD | PMID:32234424 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SLC35E4 mRNA | CTD | PMID:25181051 | bisphenol A | multiple interactions | ISO | RGD:1602959 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of SLC35E4 mRNA | CTD | PMID:28628672 | bisphenol F | multiple interactions | ISO | RGD:1602959 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SLC35E4 mRNA | CTD | PMID:28628672 | C60 fullerene | increases expression | EXP | | 6480464 | fullerene C60 results in increased expression of SLC35E4 mRNA | CTD | PMID:19167457 | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of SLC35E4 mRNA | CTD | PMID:33453195 | choline | multiple interactions | ISO | RGD:734095 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SLC35E4 mRNA | CTD | PMID:20938992 | cisplatin | increases expression | ISO | RGD:1602959 | 6480464 | Cisplatin results in increased expression of SLC35E4 mRNA | CTD | PMID:19561079 | copper(II) sulfate | increases expression | ISO | RGD:1602959 | 6480464 | Copper Sulfate results in increased expression of SLC35E4 mRNA | CTD | PMID:19549813 | dexamethasone | multiple interactions | ISO | RGD:1602959 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of SLC35E4 mRNA more ... | CTD | PMID:28628672 | diazinon | increases methylation | ISO | RGD:1602959 | 6480464 | Diazinon results in increased methylation of SLC35E4 gene | CTD | PMID:22964155 | dimethyl sulfoxide | affects expression | ISO | RGD:1602959 | 6480464 | Dimethyl Sulfoxide affects the expression of SLC35E4 mRNA | CTD | PMID:24834073 | dioxygen | decreases expression | ISO | RGD:1602959 | 6480464 | Oxygen deficiency results in decreased expression of SLC35E4 mRNA | CTD | PMID:26516004 | doxorubicin | decreases expression | ISO | RGD:1602959 | 6480464 | Doxorubicin results in decreased expression of SLC35E4 mRNA | CTD | PMID:29803840 | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of SLC35E4 mRNA | CTD | PMID:29391264 | entinostat | increases expression | ISO | RGD:1602959 | 6480464 | entinostat results in increased expression of SLC35E4 mRNA | CTD | PMID:27188386 | ethanol | affects splicing | ISO | RGD:734095 | 6480464 | Ethanol affects the splicing of SLC35E4 mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | increases expression | ISO | RGD:1602959 | 6480464 | Ethyl Methanesulfonate results in increased expression of SLC35E4 mRNA | CTD | PMID:23649840 | folic acid | multiple interactions | ISO | RGD:734095 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SLC35E4 mRNA | CTD | PMID:20938992 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of SLC35E4 mRNA | CTD | PMID:33387578 | indometacin | multiple interactions | ISO | RGD:1602959 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of SLC35E4 mRNA more ... | CTD | PMID:28628672 | L-methionine | multiple interactions | ISO | RGD:734095 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SLC35E4 mRNA | CTD | PMID:20938992 | lead(0) | affects expression | ISO | RGD:1602959 | 6480464 | Lead affects the expression of SLC35E4 mRNA | CTD | PMID:28903495 | lead(2+) | affects expression | ISO | RGD:1602959 | 6480464 | Lead affects the expression of SLC35E4 mRNA | CTD | PMID:28903495 | methyl methanesulfonate | increases expression | ISO | RGD:1602959 | 6480464 | Methyl Methanesulfonate results in increased expression of SLC35E4 mRNA | CTD | PMID:23649840 | N-Nitrosopyrrolidine | increases expression | ISO | RGD:1602959 | 6480464 | N-Nitrosopyrrolidine results in increased expression of SLC35E4 mRNA | CTD | PMID:32234424 | naphthalenes | decreases expression | EXP | | 6480464 | Naphthalenes results in decreased expression of SLC35E4 protein | CTD | PMID:17337753 | paracetamol | affects expression | ISO | RGD:734095 | 6480464 | Acetaminophen affects the expression of SLC35E4 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of SLC35E4 mRNA | CTD | PMID:33387578 | paracetamol | increases expression | ISO | RGD:1602959 | 6480464 | Acetaminophen results in increased expression of SLC35E4 mRNA | CTD | PMID:26690555, PMID:29067470 | rac-lactic acid | decreases expression | ISO | RGD:1602959 | 6480464 | Lactic Acid results in decreased expression of SLC35E4 mRNA | CTD | PMID:30851411 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of SLC35E4 mRNA | CTD | PMID:34492290 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of SLC35E4 mRNA | CTD | PMID:33387578 | triclosan | increases expression | ISO | RGD:1602959 | 6480464 | Triclosan results in increased expression of SLC35E4 mRNA | CTD | PMID:30510588 | undecane | decreases expression | EXP | | 6480464 | undecane results in decreased expression of SLC35E4 protein | CTD | PMID:17337753 | urethane | increases expression | ISO | RGD:1602959 | 6480464 | Urethane results in increased expression of SLC35E4 mRNA | CTD | PMID:28818685 | valproic acid | increases methylation | ISO | RGD:1602959 | 6480464 | Valproic Acid results in increased methylation of SLC35E4 gene | CTD | PMID:29154799 | valproic acid | increases expression | ISO | RGD:734095 | 6480464 | Valproic Acid results in increased expression of SLC35E4 mRNA | CTD | PMID:21427059 | valproic acid | increases expression | ISO | RGD:1602959 | 6480464 | Valproic Acid results in increased expression of SLC35E4 mRNA | CTD | PMID:23179753, PMID:29154799 | valproic acid | affects expression | ISO | RGD:1602959 | 6480464 | Valproic Acid affects the expression of SLC35E4 mRNA | CTD | PMID:25979313 | |