Slc35e4 (solute carrier family 35, member E4)

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Gene: Slc35e4 (solute carrier family 35, member E4) Rattus norvegicus

Analyze

Symbol:

Slc35e4

Name:

solute carrier family 35, member E4

RGD ID:

708484

Description:

Predicted to enable antiporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be active in Golgi apparatus. Orthologous to human SLC35E4 (solute carrier family 35 member E4); INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC266687; MGC93128; putative phosphate-phosphoenolpyruvate translocator; solute carrier family 35 member E4

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	14	78,803,320 - 78,810,186 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	78,803,323 - 78,810,241 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	83,244,360 - 83,251,224 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	14	84,484,442 - 84,491,306 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	14	80,930,049 - 80,936,871 (-)	NCBI	Rnor_WKY
Rnor_6.0	14	84,163,971 - 84,170,835 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	84,163,972 - 84,170,835 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	84,847,696 - 84,854,560 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	84,569,021 - 84,575,885 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	84,588,166 - 84,595,026 (-)	NCBI
Celera	14	77,715,330 - 77,722,194 (-)	NCBI		Celera
Cytogenetic Map	14	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,3,5-trinitro-1,3,5-triazinane (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

2,4-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

acetamide (EXP)

ammonium chloride (EXP)

amphetamine (EXP)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

C60 fullerene (EXP)

cadmium dichloride (EXP)

choline (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

dexamethasone (ISO)

diazinon (ISO)

dimethyl sulfoxide (ISO)

dioxygen (ISO)

doxorubicin (ISO)

endosulfan (EXP)

entinostat (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

folic acid (ISO)

gentamycin (EXP)

indometacin (ISO)

L-methionine (ISO)

lead(0) (ISO)

lead(2+) (ISO)

methyl methanesulfonate (ISO)

N-Nitrosopyrrolidine (ISO)

naphthalenes (EXP)

paracetamol (EXP,ISO)

rac-lactic acid (ISO)

thioacetamide (EXP)

trichloroethene (EXP)

triclosan (ISO)

undecane (EXP)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

transmembrane transport (IEA)

Cellular Component

Golgi apparatus (IBA)

membrane (IEA)

Molecular Function

antiporter activity (IBA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932

Genomics

Comparative Map Data

Slc35e4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	14	78,803,320 - 78,810,186 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	78,803,323 - 78,810,241 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	83,244,360 - 83,251,224 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	14	84,484,442 - 84,491,306 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	14	80,930,049 - 80,936,871 (-)	NCBI	Rnor_WKY
Rnor_6.0	14	84,163,971 - 84,170,835 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	84,163,972 - 84,170,835 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	84,847,696 - 84,854,560 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	84,569,021 - 84,575,885 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	84,588,166 - 84,595,026 (-)	NCBI
Celera	14	77,715,330 - 77,722,194 (-)	NCBI		Celera
Cytogenetic Map	14	q21	NCBI

SLC35E4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	22	30,635,781 - 30,669,019 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	22	30,635,781 - 30,669,016 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	22	31,031,768 - 31,065,006 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	29,361,793 - 29,373,862 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	22	14,831,889 - 14,843,953 (+)	NCBI		Celera
Cytogenetic Map	22	q12.2	NCBI
HuRef	22	13,994,152 - 14,006,208 (+)	NCBI		HuRef
CHM1_1	22	30,991,527 - 31,003,586 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	22	31,097,725 - 31,132,558 (+)	NCBI		T2T-CHM13v2.0

Slc35e4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	3,857,022 - 3,864,664 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	3,857,021 - 3,864,664 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	3,907,022 - 3,914,664 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	3,907,021 - 3,914,664 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	3,807,025 - 3,814,667 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	3,807,025 - 3,814,667 (-)	NCBI		MGSCv36	mm8
Celera	11	4,401,551 - 4,409,193 (-)	NCBI		Celera
Cytogenetic Map	11	A1	NCBI

Slc35e4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955455	4,853,632 - 4,863,617 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955455	4,853,632 - 4,863,617 (+)	NCBI	ChiLan1.0	ChiLan1.0

SLC35E4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	22	43,292,349 - 43,322,567 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	22	11,660,947 - 11,720,447 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	22	29,462,404 - 29,520,761 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	22	29,462,404 - 29,475,749 (+)	Ensembl	panpan1.1		panPan2

SLC35E4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	23,714,960 - 23,720,977 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	23,715,105 - 23,720,444 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	23,585,328 - 23,591,712 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	24,098,852 - 24,105,237 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	26	23,800,265 - 23,806,650 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	24,062,897 - 24,069,280 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	24,123,483 - 24,129,869 (+)	NCBI		UU_Cfam_GSD_1.0

Slc35e4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	116,641,478 - 116,648,502 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936904	85,727 - 92,070 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936904	85,729 - 92,697 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC35E4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	47,520,089 - 47,526,704 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	47,518,602 - 47,550,157 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	50,630,699 - 50,637,846 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC35E4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	13,516,718 - 13,529,361 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	19	13,519,018 - 13,528,501 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666045	112,597,200 - 112,608,473 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc35e4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624747	6,992,931 - 7,002,037 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624747	6,992,939 - 7,002,037 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Slc35e4
41 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	63
Count of miRNA genes:	56
Interacting mature miRNAs:	61
Transcripts:	ENSRNOT00000005646
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631839	Niddm37	Non-insulin dependent diabetes mellitus QTL 37	3.37		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	11030622	95876975	Rat
70187	Pancm5	Pancreatic morphology QTL 5	16.7		pancreas mass (VT:0010144)	pancreas weight to body weight ratio (CMO:0000630)	14	30320092	80829842	Rat
2313048	Bss84	Bone structure and strength QTL 84	3.1	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	14	37669719	82669719	Rat
2313084	Bss83	Bone structure and strength QTL 83	2.9	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	14	37669719	82669719	Rat
2313089	Bss81	Bone structure and strength QTL 81	3.4	0.0001	body length (VT:0001256)	body length, nose to rump (CMO:0000079)	14	37669719	82669719	Rat
2313100	Bss82	Bone structure and strength QTL 82	3	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	14	37669719	82669719	Rat
738037	Hcas6	Hepatocarcinoma susceptibility QTL 6	2.93		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	14	39057237	83368335	Rat
631523	Pia13	Pristane induced arthritis QTL 13	3.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	14	40793460	98037301	Rat
1300136	Rf22	Renal function QTL 22	3.9		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	14	42262529	95023211	Rat
1549834	Scl45	Serum cholesterol level QTL 45	5.8		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	14	50023211	95023211	Rat
2300197	Scl59	Serum cholesterol level QTL 59			blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	14	55147478	100147478	Rat
9590294	Uminl4	Urine mineral level QTL 4	5.66	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	14	55624247	100624247	Rat
9589034	Epfw11	Epididymal fat weight QTL 11	6	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	14	55624247	100624247	Rat
2317879	Alcrsp27	Alcohol response QTL 27	3.3	0.63	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	14	56631369	101631369	Rat
634328	Hc5	Hypercalciuria QTL 5	2.3		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	14	58184885	103184885	Rat
70153	Bp59	Blood pressure QTL 59	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	14	68757796	83368335	Rat
1582259	Gluco23	Glucose level QTL 23	3.1	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	70053989	104886043	Rat
1641900	Alcrsp11	Alcohol response QTL 11			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	14	70053989	104886043	Rat
1582197	Gluco27	Glucose level QTL 27	3.4	0.0006	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	73415323	92554092	Rat
1582209	Gluco20	Glucose level QTL 20	3.8	0.0005	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	73415323	92554092	Rat
1582236	Gluco22	Glucose level QTL 22	3.3	0.0164	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	73415323	92554092	Rat
1582255	Gluco29	Glucose level QTL 29	3.1	0.0025	blood glucose amount (VT:0000188)	absolute change in blood glucose level area under curve (CMO:0002034)	14	73415323	92554092	Rat
1582250	Gluco26	Glucose level QTL 26	3.3	0.0009	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	73415323	95876975	Rat

Markers in Region

RH128598

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	78,803,372 - 78,803,555 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	84,164,022 - 84,164,204	NCBI	Rnor6.0
Rnor_5.0	14	84,847,747 - 84,847,929	UniSTS	Rnor5.0
RGSC_v3.4	14	84,569,072 - 84,569,254	UniSTS	RGSC3.4
Celera	14	77,715,381 - 77,715,563	UniSTS
RH 3.4 Map	14	545.2	UniSTS
Cytogenetic Map	14	q21	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2						6	9	54		6	11	6
Low	1	43	57	41	19	41	2	2	20	35	35		2
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_153316	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091642	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091643	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF182714	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC085693	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000254	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000005646 ⟹ ENSRNOP00000005646

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	78,803,323 - 78,810,241 (-)	Ensembl
Rnor_6.0 Ensembl	14	84,163,972 - 84,170,835 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000080413 ⟹ ENSRNOP00000068680

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	14	84,164,470 - 84,170,301 (-)	Ensembl

RefSeq Acc Id:

NM_153316 ⟹ NP_695228

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	78,803,322 - 78,810,186 (-)	NCBI
Rnor_6.0	14	84,163,971 - 84,170,835 (-)	NCBI
Rnor_5.0	14	84,847,696 - 84,854,560 (-)	NCBI
RGSC_v3.4	14	84,569,021 - 84,575,885 (-)	RGD
Celera	14	77,715,330 - 77,722,194 (-)	RGD

Sequence:

show sequence

CGCAGTCAGAGCAGCCTGCGCAGCTGCAGCCAGTCCGAGCTCGCGGTTCTGCGTCTGCCGGCCC
ATCAGCGTCTATTCCCCGCACAGTAAGAGGCGAAGGGGGGCTGGAGGAGGGGACTGCGACCTCC
GTTCCCTCGCTCGGAACATTATCGACCCTGCCTGGCCTGGTCACGGCCTGAGCACCAAACATGC
AGGAGGTCGGGATCAGTGTCCTCATCCTGACAGTCTGGGGACCGAAGATGGAAAAAGGCAAGCG
GATTCTGTGTAAAACCATCGCGTGAGCTCCGGGCGAGGAGGAGGGAGAAGACCTCCCCTGGTGC
GGGAGGTGCCCAGGGCTTACGAGGCCTGGGTGGGCACCAGCCAGTCCGGCATCTCAGCAGCCAC
GACCTCGGTTCTTCTCTGACGGAACCAGAATTATCGGCTGGCTCAGGGTCTAGCATCTGAAGCA
GTGCCCTCTCCTATCTGAGGAATCAGGACCTGGCTCAGCGAGTCCCTGGAAAAGCCTGCCTTCC
TGCCCCAGCCCTACTGGTGCGGATGTGCCGCTGCCCACTGGAGCACCATGAAGTCAGGATGACC
TCAGCCGAAGCAATTGCTGTGGCTGGAAGTGCCCAGGAGCATGGCCGTCCCAAGTGGCCTCCTG
ACAAACCTCAAGTCCTTGGGCAGCCTGCTCTGGCGAGAGTGGTTGTGGCAGCACTGGTGTGGCT
GTTGGCAGGAGCCAGCATGTCAAGTCTCAACAAGTGGATCTTCACAGTGCATGGCTTCGGACGG
CCCCTGTTATTGTCAGCCCTGCACATGCTGGCAGCCGCTGTGGCATGCCACTGGGGGGCCCAGC
GACCCGTGCCCCATAGCATCCACCGCAGGGTGCTGTTACTCAGCCTCACCTTCGGGACCTCCAT
GGCGTGTGGCAACGTGGGCCTGAGCACTGTCCCCTTGGACCTAGCACAGCTAGCCACCACCACC
ACACCACTGTTCACTTTGGCCTTGTCTGCGTTGCTGCTTGGCCGAAGACACCATCCCCTGCAGT
TTGCTGCCATGGGTCCGCTCTGCCTAGGGGCTGCATGCAGTCTGGCTGGAGAGCTCCGGGCACC
TCCTGCTGGTTGTGGCTTCTTGCTGGTGGCCACCTGTCTCCGAGGTTTCAAGTCTGTTCAACAG
AGTGCTCTGCTGCAGGAAGAGAGGCTAGATGCGGTGACTCTGCTGTACGCCACTTCTTTGCCCA
GTTTCTGCCTGCTGGCAGGCGCCGCGCTGGTGCTGGAGGCTGGTGCCGCCCCACCGCTGCCTCC
CACCGACTCTCGCCTCTGGGCCTGCGTCCTGCTCAGCTGCTTCTTGTCTGTAGTCTACAACCTG
GCCAGCTTCTCCTTGCTGGCACTCACATCTGCCCTCACCGTCCACGTACTGGGCAACCTCACAG
TTGTGGGTAACCTCATCCTGTCCCGGCTCCTGTTCGGCAGCCACCTCAGCGCTCTCAGCTATGT
GGGCATCGCTCTCACCCTTTCAGGAATGTTTCTTTATCACAACTGTGAGTCTGTGGCCTCCTGG
GCTACCCGCCGGGGGTTGTGGAACAGGGACCAGCCTGGCAAAGGTCTTTGAGACCTGGGAGAGC
TCATGAACTAGACCCGGACAGCCAGCCCCAGCCTGAATCTAACCTTGGACAGTGGCCATGACAG
AGGCCAGGGCAGGGGAAGAAGGTACCTTCTGGAAGGGCTGCCTGGGAGGCTACACCAGGGATCT
CAGAGAGACCCACCTCCTGTCCCTGCCTTCCTCACGACTCACAGCAAACCCTGCCATTGGATGG
TGGGTCCAAGTCTGGCACATGCGCCTGTCAGATGGATTGGTGTCAGTGACTATGATGAAGATTG
CTGGGCAAACTTAGGAAAACCTCAAAGTGTTATGAGGAAGACATTGCCCGGCGGTTGCACAGTC
TTTCCTGGGGGCAGGATGTGAGGGTCACCAGAGAAGGCTTCTTCATGGCTGGGCTCCCCTAAAG
ATGGGGTAGTCTATGCCAACTTCAGGTAGCTACTGCAGCCTCACTCTGGTGCCTCCCCTGGATT
TGGGTCTTCCATCCCCAATAAAGTATTTTTTCTTGGGAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039091642 ⟹ XP_038947570

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	78,804,412 - 78,809,681 (-)	NCBI

RefSeq Acc Id:

XM_039091643 ⟹ XP_038947571

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	78,803,320 - 78,806,436 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_695228	(Get FASTA)	NCBI Sequence Viewer
	XP_038947570	(Get FASTA)	NCBI Sequence Viewer
	XP_038947571	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD55791	(Get FASTA)	NCBI Sequence Viewer
	AAH85693	(Get FASTA)	NCBI Sequence Viewer
	Q5RKL7	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_695228 ⟸ NM_153316

- UniProtKB:

Q5RKL7 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MCRCPLEHHEVRMTSAEAIAVAGSAQEHGRPKWPPDKPQVLGQPALARVVVAALVWLLAGASMS
SLNKWIFTVHGFGRPLLLSALHMLAAAVACHWGAQRPVPHSIHRRVLLLSLTFGTSMACGNVGL
STVPLDLAQLATTTTPLFTLALSALLLGRRHHPLQFAAMGPLCLGAACSLAGELRAPPAGCGFL
LVATCLRGFKSVQQSALLQEERLDAVTLLYATSLPSFCLLAGAALVLEAGAAPPLPPTDSRLWA
CVLLSCFLSVVYNLASFSLLALTSALTVHVLGNLTVVGNLILSRLLFGSHLSALSYVGIALTLS
GMFLYHNCESVASWATRRGLWNRDQPGKGL

hide sequence

RefSeq Acc Id:

ENSRNOP00000068680 ⟸ ENSRNOT00000080413

RefSeq Acc Id:

ENSRNOP00000005646 ⟸ ENSRNOT00000005646

RefSeq Acc Id:	XP_038947571 ⟸ XM_039091643
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038947570 ⟸ XM_039091642
- Peptide Label:	isoform X1

Protein Domains

EamA

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5RKL7-F1-model_v2	AlphaFold	Q5RKL7	1-350	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699432

Promoter ID:

EPDNEW_R9957

Type:

initiation region

Name:

Slc35e4_1

Description:

solute carrier family 35, member E4

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	14	84,170,880 - 84,170,940	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:708484	AgrOrtholog
BioCyc Gene	G2FUF-15208	BioCyc
Ensembl Genes	ENSRNOG00000004168	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSRNOP00000005646	ENTREZGENE
	ENSRNOP00000005646.3	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000005646	ENTREZGENE
	ENSRNOT00000005646.5	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7191218	IMAGE-MGC_LOAD
InterPro	Sugar_P_trans_dom	UniProtKB/Swiss-Prot
KEGG Report	rno:266687	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93128	IMAGE-MGC_LOAD
NCBI Gene	266687	ENTREZGENE
PANTHER	SOLUTE CARRIER FAMILY 35	UniProtKB/Swiss-Prot
	SOLUTE CARRIER FAMILY 35 MEMBER E4	UniProtKB/Swiss-Prot
Pfam	TPT	UniProtKB/Swiss-Prot
PhenoGen	Slc35e4	PhenoGen
Superfamily-SCOP	Multidrug resistance efflux transporter EmrE	UniProtKB/Swiss-Prot
UniProt	Q5RKL7	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-07-08	Slc35e4	solute carrier family 35, member E4	LOC266687	putative phosphate-phosphoenolpyruvate translocator	Symbol and Name updated	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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