Camk2b (calcium/calmodulin-dependent protein kinase II beta) - Rat Genome Database

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Gene: Camk2b (calcium/calmodulin-dependent protein kinase II beta) Rattus norvegicus
Analyze
Symbol: Camk2b
Name: calcium/calmodulin-dependent protein kinase II beta
RGD ID: 2262
Description: Exhibits calmodulin-dependent protein kinase activity; phospholipase binding activity; and protein kinase binding activity. A structural constituent of postsynaptic actin cytoskeleton. Involved in several processes, including cellular response to homocysteine; hippocampal neuron apoptotic process; and regulation of synapse organization. Localizes to several cellular components, including glutamatergic synapse; perikaryon; and postsynaptic density. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 54. Orthologous to human CAMK2B (calcium/calmodulin dependent protein kinase II beta); PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; p38 MAPK signaling pathway; type II interferon signaling pathway; INTERACTS WITH (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ca++/calmodulin-dependent protein kinase II beta subunit; Ca++/calmodulin-dependent protein kinase II, beta subunit; calcium/calmodulin-dependent protein kinase (CaM kinase) II beta; calcium/calmodulin-dependent protein kinase II beta subunit; calcium/calmodulin-dependent protein kinase II, beta; calcium/calmodulin-dependent protein kinase type II beta chain; calcium/calmodulin-dependent protein kinase type II subunit beta; caM kinase II subunit beta; caM-kinase II beta chain; caMK-II subunit beta; Ck2b
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21480,845,206 - 80,934,172 (-)NCBI
Rnor_6.0 Ensembl1486,208,901 - 86,297,652 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01486,208,876 - 86,297,727 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01486,893,062 - 86,982,256 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41486,632,686 - 86,721,281 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11486,653,834 - 86,740,406 (-)NCBI
Celera1479,728,956 - 79,817,594 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-amphetamine  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-[1-hydroxy-2-[4-(phenylmethyl)-1-piperidinyl]propyl]phenol  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aflatoxin B2  (ISO)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (EXP)
androgen antagonist  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
azamethiphos  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP)
butan-1-ol  (ISO)
Butylparaben  (EXP)
cannabidiol  (ISO)
cannabigerol  (ISO)
carbon dioxide  (EXP)
carbon nanotube  (ISO)
chlordecone  (ISO)
chlorpyrifos  (EXP,ISO)
choline  (EXP)
ciguatoxin CTX1B  (ISO)
cisplatin  (EXP)
clozapine  (EXP)
cocaine  (EXP,ISO)
cyfluthrin  (ISO)
cyhalothrin  (EXP)
cypermethrin  (ISO)
DDE  (EXP)
dibutyl phthalate  (EXP)
diclofenac  (EXP)
dieldrin  (EXP)
diethylstilbestrol  (ISO)
dioxygen  (EXP,ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
enzacamene  (EXP)
epoxiconazole  (EXP)
ethanol  (EXP,ISO)
ferroheme b  (ISO)
folic acid  (ISO)
furan  (EXP)
glyphosate  (ISO)
haloperidol  (EXP)
heme b  (ISO)
isoprenaline  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
linuron  (EXP)
lovastatin  (EXP)
malathion  (EXP)
methapyrilene  (ISO)
monosodium L-glutamate  (ISO)
nickel dichloride  (EXP)
ochratoxin A  (EXP)
ouabain  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
phencyclidine  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
prochloraz  (EXP)
procymidone  (EXP)
progesterone  (ISO)
propiconazole  (ISO)
quercitrin  (ISO)
rotenone  (ISO)
selenium atom  (ISO)
Soman  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
titanium dioxide  (ISO)
triazines  (ISO)
tributylstannane  (EXP,ISO)
trichostatin A  (EXP)
triptonide  (ISO)
tris(2-chloroethyl) phosphate  (EXP)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)
venlafaxine hydrochloride  (EXP)
vinclozolin  (EXP)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
1. Bennett MK and Kennedy MB, Proc Natl Acad Sci U S A 1987 Apr;84(7):1794-8.
2. Bingol B, etal., Cell. 2010 Feb 19;140(4):567-78. doi: 10.1016/j.cell.2010.01.024.
3. Coultrap SJ and Bayer KU, Trends Neurosci. 2012 Oct;35(10):607-18. doi: 10.1016/j.tins.2012.05.003. Epub 2012 Jun 19.
4. De Felice FG, etal., Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1971-6. doi: 10.1073/pnas.0809158106. Epub 2009 Feb 2.
5. Fang M, etal., Int J Clin Exp Med. 2014 Jul 15;7(7):1659-68. eCollection 2014.
6. Fink CC, etal., Neuron. 2003 Jul 17;39(2):283-97.
7. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
8. GOA data from the GO Consortium
9. Johansson FK, etal., Oncogene. 2005 Jun 2;24(24):3896-905. doi: 10.1038/sj.onc.1208553.
10. Lisman J, etal., Nat Rev Neurosci. 2012 Feb 15;13(3):169-82. doi: 10.1038/nrn3192.
11. Malinow R, etal., Science. 1989 Aug 25;245(4920):862-6.
12. MGD data from the GO Consortium
13. NCBI rat LocusLink and RefSeq merged data July 26, 2002
14. Novak G, etal., Int J Dev Neurosci. 2013 May;31(3):189-95. doi: 10.1016/j.ijdevneu.2013.01.001. Epub 2013 Jan 10.
15. Ochiishi T, etal., Brain Res. 1994 Oct 3;659(1-2):179-93.
16. Okamoto K, etal., Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6418-23. Epub 2007 Apr 2.
17. Okuno H, etal., Cell. 2012 May 11;149(4):886-98. doi: 10.1016/j.cell.2012.02.062.
18. Pipeline to import KEGG annotations from KEGG into RGD
19. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
20. RGD automated data pipeline
21. RGD automated import pipeline for gene-chemical interactions
22. RGD comprehensive gene curation
23. Song B, etal., J Biol Chem. 2010 Dec 24;285(52):41122-34. doi: 10.1074/jbc.M110.130351. Epub 2010 Sep 14.
24. Swulius MT, etal., J Comp Neurol. 2010 Oct 15;518(20):4243-60. doi: 10.1002/cne.22451.
25. Waggener CT, etal., J Neurosci. 2013 Jun 19;33(25):10453-8. doi: 10.1523/JNEUROSCI.5875-12.2013.
26. Wang P, etal., Neurotoxicology. 2013 Jul;37:51-62. doi: 10.1016/j.neuro.2013.03.007. Epub 2013 Apr 1.
27. Wang Z, etal., J Biol Chem. 2005 Feb 25;280(8):6840-9. Epub 2004 Dec 2.
28. Xue J, etal., Brain Res Dev Brain Res 2002 Sep 20;138(1):61-70.
29. Yamamoto H Tanpakushitsu Kakusan Koso 2002 Mar;47(3):241-7.
Additional References at PubMed
PMID:7821422   PMID:9755160   PMID:9882483   PMID:11264466   PMID:11597763   PMID:12660151   PMID:15312654   PMID:16436603   PMID:16928958   PMID:17114649   PMID:17367784   PMID:18562151  
PMID:18817731   PMID:18840684   PMID:19047462   PMID:19292454   PMID:19332541   PMID:19503086   PMID:20124353   PMID:20668654   PMID:21610080   PMID:21718540   PMID:21725312   PMID:21952434  
PMID:22114270   PMID:23352984   PMID:23990563   PMID:24625528   PMID:24866099   PMID:25002582   PMID:25416956   PMID:25644714   PMID:25931508   PMID:27611779   PMID:28553222   PMID:29100089  
PMID:29476059   PMID:29675826   PMID:30053369   PMID:30662904  


Genomics

Comparative Map Data
Camk2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21480,845,206 - 80,934,172 (-)NCBI
Rnor_6.0 Ensembl1486,208,901 - 86,297,652 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01486,208,876 - 86,297,727 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01486,893,062 - 86,982,256 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41486,632,686 - 86,721,281 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11486,653,834 - 86,740,406 (-)NCBI
Celera1479,728,956 - 79,817,594 (-)NCBICelera
Cytogenetic Map14q21NCBI
CAMK2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl744,217,150 - 44,334,577 (-)EnsemblGRCh38hg38GRCh38
GRCh38744,217,154 - 44,326,167 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37744,256,753 - 44,365,193 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36744,225,416 - 44,331,749 (-)NCBINCBI36hg18NCBI36
Build 34744,032,136 - 44,138,464NCBI
Celera744,354,715 - 44,422,313 (-)NCBI
Cytogenetic Map7p13NCBI
HuRef744,142,028 - 44,208,379 (-)ENTREZGENEHuRef
CHM1_1744,260,608 - 44,369,178 (-)NCBICHM1_1
CRA_TCAGchr7v2744,296,255 - 44,404,749 (-)ENTREZGENE
Camk2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,919,642 - 6,016,401 (-)NCBIGRCm39mm39
GRCm39 Ensembl115,919,644 - 6,016,362 (-)Ensembl
GRCm38115,969,629 - 6,066,357 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,969,644 - 6,066,362 (-)EnsemblGRCm38mm10GRCm38
MGSCv37115,869,645 - 5,965,751 (-)NCBIGRCm37mm9NCBIm37
MGSCv36115,869,675 - 5,965,751 (-)NCBImm8
Celera116,461,702 - 6,553,628 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map113.89NCBI
Camk2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554567,713,552 - 7,760,207 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554567,711,583 - 7,760,506 (+)NCBIChiLan1.0ChiLan1.0
CAMK2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1745,001,240 - 45,110,499 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl745,001,267 - 45,110,342 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0744,930,859 - 45,040,078 (-)NCBIMhudiblu_PPA_v0panPan3
Camk2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511899,971,714 - 100,066,726 (-)NCBI
SpeTri2.0NW_00493647819,183,493 - 19,278,457 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CAMK2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1850,861,466 - 50,957,945 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11850,862,225 - 50,956,263 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21855,764,825 - 55,851,601 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CAMK2B
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12114,342,751 - 14,451,274 (+)NCBI
ChlSab1.1 Ensembl2114,342,892 - 14,451,282 (+)Ensembl
Vero_WHO_p1.0NW_0236660628,066,177 - 8,195,979 (-)NCBI
Camk2b
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247407,750,327 - 7,828,891 (+)NCBI

Position Markers
D14Rat93  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21480,867,695 - 80,867,915 (+)MAPPER
Rnor_6.01486,231,357 - 86,231,574NCBIRnor6.0
Rnor_5.01486,915,537 - 86,915,754UniSTSRnor5.0
RGSC_v3.41486,655,205 - 86,655,423RGDRGSC3.4
RGSC_v3.41486,655,206 - 86,655,423UniSTSRGSC3.4
RGSC_v3.11486,674,350 - 86,674,568RGD
Celera1479,751,450 - 79,751,667UniSTS
SHRSP x BN Map1444.8999RGD
SHRSP x BN Map1444.8999UniSTS
Cytogenetic Map14q21UniSTS
PMC145549P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21480,933,912 - 80,934,108 (+)MAPPER
Rnor_6.01486,297,571 - 86,297,766NCBIRnor6.0
RGSC_v3.41486,721,200 - 86,721,395UniSTSRGSC3.4
Cytogenetic Map14q21UniSTS
BF405463  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21480,845,274 - 80,845,444 (+)MAPPER
Rnor_6.01486,208,938 - 86,209,107NCBIRnor6.0
Rnor_5.01486,893,124 - 86,893,293UniSTSRnor5.0
RGSC_v3.41486,632,748 - 86,632,917UniSTSRGSC3.4
Celera1479,729,018 - 79,729,187UniSTS
RH 3.4 Map14575.6UniSTS
Cytogenetic Map14q21UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1412680424106641756Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1442442731108833671Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1443910761105074364Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1451818462105074364Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1460980905105980905Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1460980905105980905Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)146187332388870994Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1461993178106993178Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1463548095108548095Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)147339146788870994Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1478172765102549388Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)1478172765102549388Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1478172765102549388Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1478172765102549388Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1478172765106641756Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1478446303110402569Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1480049285115493446Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1480049285115493446Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)1485307663106641756Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:767
Count of miRNA genes:235
Interacting mature miRNAs:282
Transcripts:ENSRNOT00000005441, ENSRNOT00000045935
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 8 11 64 6 8
Low 2 38 28 13 18 13 10 34 35 11
Below cutoff 5 28 27 1 27 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001042354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001042356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_021739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB054054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC110110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF069731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB616255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB692429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB728582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO395982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO406099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M16112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X83375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000067162   ⟹   ENSRNOP00000058882
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1486,210,876 - 86,297,623 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000081607   ⟹   ENSRNOP00000068938
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1486,208,901 - 86,297,652 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000085265   ⟹   ENSRNOP00000073205
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1486,208,901 - 86,297,652 (-)Ensembl
RefSeq Acc Id: NM_001042354   ⟹   NP_001035813
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21480,845,213 - 80,933,994 (-)NCBI
Rnor_6.01486,208,876 - 86,297,652 (-)NCBI
Rnor_5.01486,893,062 - 86,982,256 (-)NCBI
RGSC_v3.41486,632,686 - 86,721,281 (-)RGD
Celera1479,728,956 - 79,817,594 (-)RGD
Sequence:
RefSeq Acc Id: NM_001042356   ⟹   NP_001035815
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21480,845,213 - 80,933,994 (-)NCBI
Rnor_6.01486,208,876 - 86,297,652 (-)NCBI
Rnor_5.01486,893,062 - 86,982,256 (-)NCBI
RGSC_v3.41486,632,686 - 86,721,281 (-)RGD
Celera1479,728,956 - 79,817,594 (-)RGD
Sequence:
RefSeq Acc Id: NM_021739   ⟹   NP_068507
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21480,845,213 - 80,933,994 (-)NCBI
Rnor_6.01486,208,876 - 86,297,652 (-)NCBI
Rnor_5.01486,893,062 - 86,982,256 (-)NCBI
RGSC_v3.41486,632,686 - 86,721,281 (-)RGD
Celera1479,728,956 - 79,817,594 (-)RGD
Sequence:
RefSeq Acc Id: XM_006251170   ⟹   XP_006251232
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21480,845,206 - 80,934,163 (-)NCBI
Rnor_6.01486,210,851 - 86,297,724 (-)NCBI
Rnor_5.01486,893,062 - 86,982,256 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006251171   ⟹   XP_006251233
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21480,845,206 - 80,934,166 (-)NCBI
Rnor_6.01486,210,851 - 86,297,724 (-)NCBI
Rnor_5.01486,893,062 - 86,982,256 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006251172   ⟹   XP_006251234
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21480,845,206 - 80,934,169 (-)NCBI
Rnor_6.01486,210,851 - 86,297,723 (-)NCBI
Rnor_5.01486,893,062 - 86,982,256 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006251174   ⟹   XP_006251236
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21480,845,206 - 80,934,172 (-)NCBI
Rnor_6.01486,210,851 - 86,297,724 (-)NCBI
Rnor_5.01486,893,062 - 86,982,256 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006251176   ⟹   XP_006251238
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21480,845,206 - 80,934,150 (-)NCBI
Rnor_6.01486,210,851 - 86,297,719 (-)NCBI
Rnor_5.01486,893,062 - 86,982,256 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006251177   ⟹   XP_006251239
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21480,845,206 - 80,934,150 (-)NCBI
Rnor_6.01486,210,851 - 86,297,718 (-)NCBI
Rnor_5.01486,893,062 - 86,982,256 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599068   ⟹   XP_017454557
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21480,845,206 - 80,934,169 (-)NCBI
Rnor_6.01486,210,851 - 86,297,723 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599069   ⟹   XP_017454558
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21480,845,206 - 80,934,172 (-)NCBI
Rnor_6.01486,210,851 - 86,297,727 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599070   ⟹   XP_017454559
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21480,845,206 - 80,934,172 (-)NCBI
Rnor_6.01486,210,851 - 86,297,724 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599071   ⟹   XP_017454560
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21480,845,206 - 80,934,151 (-)NCBI
Rnor_6.01486,210,851 - 86,297,718 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599072   ⟹   XP_017454561
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21480,845,206 - 80,934,158 (-)NCBI
Rnor_6.01486,210,851 - 86,297,723 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039091616   ⟹   XP_038947544
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21480,845,206 - 80,934,163 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_068507   ⟸   NM_021739
- Peptide Label: isoform 2
- UniProtKB: P08413 (UniProtKB/Swiss-Prot),   G3V9G3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001035815   ⟸   NM_001042356
- Peptide Label: isoform 3
- UniProtKB: P08413 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001035813   ⟸   NM_001042354
- Peptide Label: isoform 1
- UniProtKB: F1LNI8 (UniProtKB/TrEMBL),   Q63094 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251236   ⟸   XM_006251174
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_006251239   ⟸   XM_006251177
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_006251234   ⟸   XM_006251172
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006251238   ⟸   XM_006251176
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_006251233   ⟸   XM_006251171
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006251232   ⟸   XM_006251170
- Peptide Label: isoform X1
- UniProtKB: F1LUE2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454558   ⟸   XM_017599069
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017454559   ⟸   XM_017599070
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_017454557   ⟸   XM_017599068
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017454561   ⟸   XM_017599072
- Peptide Label: isoform X11
- Sequence:
RefSeq Acc Id: XP_017454560   ⟸   XM_017599071
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: ENSRNOP00000058882   ⟸   ENSRNOT00000067162
RefSeq Acc Id: ENSRNOP00000073205   ⟸   ENSRNOT00000085265
RefSeq Acc Id: ENSRNOP00000068938   ⟸   ENSRNOT00000081607
RefSeq Acc Id: XP_038947544   ⟸   XM_039091616
- Peptide Label: isoform X12
Protein Domains
Protein kinase

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699476
Promoter ID:EPDNEW_R9992
Type:initiation region
Name:Camk2b_1
Description:calcium/calmodulin-dependent protein kinase II beta
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01486,297,648 - 86,297,708EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2262 AgrOrtholog
Ensembl Genes ENSRNOG00000052080 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000058882 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000068938 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000073205 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000067162 UniProtKB/TrEMBL
  ENSRNOT00000081607 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000085265 ENTREZGENE, UniProtKB/TrEMBL
InterPro Ca/CaM-dep_prot_kinase-assoc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NTF2-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24245 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 24245 ENTREZGENE
Pfam CaMKII_AD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Camk2b PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54427 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt F1LNI8 ENTREZGENE, UniProtKB/TrEMBL
  F1LUE2 ENTREZGENE, UniProtKB/TrEMBL
  G3V9G3 ENTREZGENE, UniProtKB/TrEMBL
  KCC2B_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q63094 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-02-25 Camk2b  calcium/calmodulin-dependent protein kinase II beta  Camk2b  calcium/calmodulin-dependent protein kinase (CaM kinase) II beta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-24 Camk2b  calcium/calmodulin-dependent protein kinase (CaM kinase) II beta  Camk2b  calcium/calmodulin-dependent protein kinase II, beta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Camk2b  calcium/calmodulin-dependent protein kinase II, beta    calcium/calmodulin-dependent protein kinase II beta subunit  Name updated 1299863 APPROVED
2002-11-06 Camk2b  calcium/calmodulin-dependent protein kinase II beta subunit    Ca++/calmodulin-dependent protein kinase II, beta subunit  Name updated 625702 APPROVED
2002-06-10 Camk2b  Ca++/calmodulin-dependent protein kinase II, beta subunit      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_function beta subunit of kinase 634690
gene_process may play a role in the development of the retina 634688
gene_protein 542 amino acid protein 634690