Camk2b (calcium/calmodulin-dependent protein kinase II beta) - Rat Genome Database

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Gene: Camk2b (calcium/calmodulin-dependent protein kinase II beta) Rattus norvegicus
Analyze
Symbol: Camk2b
Name: calcium/calmodulin-dependent protein kinase II beta
RGD ID: 2262
Description: Enables calcium/calmodulin-dependent protein kinase activity; phospholipase binding activity; and protein kinase binding activity. A structural constituent of postsynaptic actin cytoskeleton. Involved in several processes, including cellular response to homocysteine; hippocampal neuron apoptotic process; and regulation of synapse organization. Acts upstream of or within long-term synaptic potentiation. Located in dendrite and perikaryon. Is active in glutamatergic synapse and postsynaptic density. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 54. Orthologous to human CAMK2B (calcium/calmodulin dependent protein kinase II beta); PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; p38 MAPK signaling pathway; type II interferon signaling pathway; INTERACTS WITH (R)-noradrenaline; (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Ca++/calmodulin-dependent protein kinase II beta subunit; Ca++/calmodulin-dependent protein kinase II, beta subunit; calcium/calmodulin-dependent protein kinase (CaM kinase) II beta; calcium/calmodulin-dependent protein kinase II beta subunit; calcium/calmodulin-dependent protein kinase II, beta; calcium/calmodulin-dependent protein kinase type II beta chain; calcium/calmodulin-dependent protein kinase type II subunit beta; caM kinase II subunit beta; caM-kinase II beta chain; caMK-II subunit beta; Ck2b
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81485,059,166 - 85,148,121 (-)NCBIGRCr8
mRatBN7.21480,845,206 - 80,934,172 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1480,845,238 - 80,933,994 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1485,247,252 - 85,335,996 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,487,349 - 86,576,085 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,936,663 - 83,025,404 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,208,876 - 86,297,727 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,208,901 - 86,297,652 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01486,893,062 - 86,982,256 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41486,632,686 - 86,721,281 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11486,653,834 - 86,740,406 (-)NCBI
Celera1479,728,956 - 79,817,594 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
(R)-noradrenaline  (EXP)
(S)-amphetamine  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-[1-hydroxy-2-[4-(phenylmethyl)-1-piperidinyl]propyl]phenol  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
androgen antagonist  (EXP)
antimycin A  (ISO)
arotinoid acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
azamethiphos  (EXP)
azoxystrobin  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
Butylparaben  (EXP)
camptothecin  (ISO)
cannabidiol  (ISO)
cannabigerol  (ISO)
cantharidin  (ISO)
carbon dioxide  (EXP)
carbon nanotube  (ISO)
CHIR 99021  (ISO)
chlordecone  (ISO)
chlorpyrifos  (EXP,ISO)
choline  (EXP)
ciguatoxin CTX1B  (ISO)
cisplatin  (EXP)
clozapine  (EXP)
cocaine  (EXP,ISO)
copper(II) chloride  (ISO)
cortisol  (ISO)
Cuprizon  (EXP)
cyfluthrin  (ISO)
cyhalothrin  (EXP)
cypermethrin  (ISO)
DDE  (EXP)
deguelin  (ISO)
dibutyl phthalate  (EXP)
diclofenac  (EXP)
dieldrin  (EXP,ISO)
diethylstilbestrol  (ISO)
dioxygen  (EXP,ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
enzacamene  (EXP)
epoxiconazole  (EXP,ISO)
ethanol  (EXP,ISO)
fenthion  (ISO)
ferroheme b  (ISO)
folic acid  (ISO)
furan  (EXP)
glyphosate  (EXP,ISO)
haloperidol  (EXP)
heme b  (ISO)
iron dichloride  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
linuron  (EXP)
lovastatin  (EXP)
malathion  (EXP)
methapyrilene  (ISO)
methidathion  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monosodium L-glutamate  (ISO)
nickel dichloride  (EXP)
Nutlin-3  (ISO)
ochratoxin A  (EXP)
ouabain  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phencyclidine  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
prochloraz  (EXP)
procymidone  (EXP)
progesterone  (ISO)
propiconazole  (ISO)
pyrimidifen  (ISO)
quercitrin  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
thifluzamide  (ISO)
titanium dioxide  (ISO)
triazines  (ISO)
tributylstannane  (EXP,ISO)
trichostatin A  (EXP)
triptonide  (ISO)
tris(2-chloroethyl) phosphate  (EXP)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)
venlafaxine hydrochloride  (EXP)
vinclozolin  (EXP)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Deduced primary structure of the beta subunit of brain type II Ca2+/calmodulin-dependent protein kinase determined by molecular cloning. Bennett MK and Kennedy MB, Proc Natl Acad Sci U S A 1987 Apr;84(7):1794-8.
2. Autophosphorylated CaMKIIalpha acts as a scaffold to recruit proteasomes to dendritic spines. Bingol B, etal., Cell. 2010 Feb 19;140(4):567-78. doi: 10.1016/j.cell.2010.01.024.
3. CaMKII regulation in information processing and storage. Coultrap SJ and Bayer KU, Trends Neurosci. 2012 Oct;35(10):607-18. doi: 10.1016/j.tins.2012.05.003. Epub 2012 Jun 19.
4. Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers. De Felice FG, etal., Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1971-6. doi: 10.1073/pnas.0809158106. Epub 2009 Feb 2.
5. Camk2b protects neurons from homocysteine-induced apoptosis with the involvement of HIF-1a signal pathway. Fang M, etal., Int J Clin Exp Med. 2014 Jul 15;7(7):1659-68. eCollection 2014.
6. Selective regulation of neurite extension and synapse formation by the beta but not the alpha isoform of CaMKII. Fink CC, etal., Neuron. 2003 Jul 17;39(2):283-97.
7. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
8. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
9. Expression analysis of genes involved in brain tumor progression driven by retroviral insertional mutagenesis in mice. Johansson FK, etal., Oncogene. 2005 Jun 2;24(24):3896-905. doi: 10.1038/sj.onc.1208553.
10. Mechanisms of CaMKII action in long-term potentiation. Lisman J, etal., Nat Rev Neurosci. 2012 Feb 15;13(3):169-82. doi: 10.1038/nrn3192.
11. Inhibition of postsynaptic PKC or CaMKII blocks induction but not expression of LTP. Malinow R, etal., Science. 1989 Aug 25;245(4920):862-6.
12. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
13. Requirement of Ca2+ and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-gamma. Nair JS, etal., Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):5971-6. doi: 10.1073/pnas.052159099. Epub 2002 Apr 23.
14. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
15. Postnatal maternal deprivation and pubertal stress have additive effects on dopamine D2 receptor and CaMKII beta expression in the striatum. Novak G, etal., Int J Dev Neurosci. 2013 May;31(3):189-95. doi: 10.1016/j.ijdevneu.2013.01.001. Epub 2013 Jan 10.
16. Specific distribution of Ca2+/calmodulin-dependent protein kinase II alpha and beta isoforms in some structures of the rat forebrain. Ochiishi T, etal., Brain Res. 1994 Oct 3;659(1-2):179-93.
17. The role of CaMKII as an F-actin-bundling protein crucial for maintenance of dendritic spine structure. Okamoto K, etal., Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6418-23. Epub 2007 Apr 2.
18. Inverse synaptic tagging of inactive synapses via dynamic interaction of Arc/Arg3.1 with CaMKIIbeta. Okuno H, etal., Cell. 2012 May 11;149(4):886-98. doi: 10.1016/j.cell.2012.02.062.
19. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
20. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
21. GOA pipeline RGD automated data pipeline
22. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
23. Comprehensive gene review and curation RGD comprehensive gene curation
24. Inhibitory phosphorylation of GSK-3 by CaMKII couples depolarization to neuronal survival. Song B, etal., J Biol Chem. 2010 Dec 24;285(52):41122-34. doi: 10.1074/jbc.M110.130351. Epub 2010 Sep 14.
25. Structure and composition of the postsynaptic density during development. Swulius MT, etal., J Comp Neurol. 2010 Oct 15;518(20):4243-60. doi: 10.1002/cne.22451.
26. CaMKIIbeta regulates oligodendrocyte maturation and CNS myelination. Waggener CT, etal., J Neurosci. 2013 Jun 19;33(25):10453-8. doi: 10.1523/JNEUROSCI.5875-12.2013.
27. Trichostatin A protects against cisplatin-induced ototoxicity by regulating expression of genes related to apoptosis and synaptic function. Wang P, etal., Neurotoxicology. 2013 Jul;37:51-62. doi: 10.1016/j.neuro.2013.03.007. Epub 2013 Apr 1.
28. Group VIA phospholipase A2 forms a signaling complex with the calcium/calmodulin-dependent protein kinase IIbeta expressed in pancreatic islet beta-cells. Wang Z, etal., J Biol Chem. 2005 Feb 25;280(8):6840-9. Epub 2004 Dec 2.
29. Developmentally regulated expression of CaMKII and iGluRs in the rat retina. Xue J, etal., Brain Res Dev Brain Res 2002 Sep 20;138(1):61-70.
30. [Molecular mechanisms of the intracellular localizations of Ca2+/calmodulin-dependent protein kinase II isoforms, and their physiological functions] Yamamoto H Tanpakushitsu Kakusan Koso 2002 Mar;47(3):241-7.
Additional References at PubMed
PMID:7821422   PMID:9755160   PMID:9882483   PMID:11264466   PMID:11597763   PMID:12660151   PMID:15312654   PMID:16436603   PMID:16928958   PMID:17114649   PMID:17367784   PMID:18562151  
PMID:18817731   PMID:18840684   PMID:19047462   PMID:19292454   PMID:19332541   PMID:19503086   PMID:20124353   PMID:20668654   PMID:21610080   PMID:21718540   PMID:21725312   PMID:21952434  
PMID:22114270   PMID:23352984   PMID:23990563   PMID:24625528   PMID:24866099   PMID:25002582   PMID:25416956   PMID:25644714   PMID:25931508   PMID:27611779   PMID:28553222   PMID:29100089  
PMID:29476059   PMID:29675826   PMID:30053369   PMID:30662904   PMID:32357304   PMID:36041587  


Genomics

Comparative Map Data
Camk2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81485,059,166 - 85,148,121 (-)NCBIGRCr8
mRatBN7.21480,845,206 - 80,934,172 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1480,845,238 - 80,933,994 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1485,247,252 - 85,335,996 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,487,349 - 86,576,085 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,936,663 - 83,025,404 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,208,876 - 86,297,727 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,208,901 - 86,297,652 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01486,893,062 - 86,982,256 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41486,632,686 - 86,721,281 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11486,653,834 - 86,740,406 (-)NCBI
Celera1479,728,956 - 79,817,594 (-)NCBICelera
Cytogenetic Map14q21NCBI
CAMK2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38744,217,154 - 44,326,013 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl744,210,019 - 44,334,577 (-)EnsemblGRCh38hg38GRCh38
GRCh37744,256,753 - 44,365,193 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36744,225,416 - 44,331,749 (-)NCBINCBI36Build 36hg18NCBI36
Build 34744,032,136 - 44,138,464NCBI
Celera744,354,715 - 44,422,313 (-)NCBICelera
Cytogenetic Map7p13NCBI
HuRef744,142,028 - 44,208,379 (-)ENTREZGENEHuRef
CHM1_1744,260,608 - 44,369,178 (-)NCBICHM1_1
T2T-CHM13v2.0744,375,741 - 44,485,432 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2744,296,255 - 44,404,749 (-)ENTREZGENE
Camk2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,919,642 - 6,016,401 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl115,919,644 - 6,016,362 (-)EnsemblGRCm39 Ensembl
GRCm38115,969,629 - 6,066,357 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,969,644 - 6,066,362 (-)EnsemblGRCm38mm10GRCm38
MGSCv37115,869,645 - 5,965,751 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36115,869,675 - 5,965,751 (-)NCBIMGSCv36mm8
Celera116,461,702 - 6,553,628 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map113.89NCBI
Camk2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554567,713,552 - 7,760,207 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554567,711,583 - 7,760,506 (+)NCBIChiLan1.0ChiLan1.0
CAMK2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2649,128,517 - 49,238,128 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1797,453,257 - 97,562,867 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0744,930,859 - 45,040,078 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1745,001,240 - 45,110,499 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl745,001,267 - 45,110,342 (-)Ensemblpanpan1.1panPan2
CAMK2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha162,142,154 - 2,219,094 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01614,642,707 - 14,719,698 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1614,642,688 - 14,732,697 (+)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.01614,274,291 - 14,351,161 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01614,254,459 - 14,331,424 (+)NCBIUU_Cfam_GSD_1.0
Camk2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511899,971,714 - 100,066,726 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647819,180,726 - 19,278,920 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647819,183,493 - 19,278,457 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CAMK2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1850,861,466 - 50,956,225 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11850,862,225 - 50,956,263 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21855,764,825 - 55,851,601 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CAMK2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12114,342,751 - 14,451,274 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2114,342,892 - 14,451,282 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660628,066,177 - 8,195,979 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Camk2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247407,750,245 - 7,831,454 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247407,750,327 - 7,828,891 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Camk2b
399 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:767
Count of miRNA genes:235
Interacting mature miRNAs:282
Transcripts:ENSRNOT00000005441, ENSRNOT00000045935
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)147995092195876975Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)146875779683368335Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1470053989104886043Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147341532392554092Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532395876975Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1456631369101631369Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1470053989104886043Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147341532392554092Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1455624247100624247Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143766971982669719Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)145002321195023211Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143905723783368335Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143766971982669719Rat

Markers in Region
D14Rat93  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81485,081,646 - 85,081,864 (+)Marker Load Pipeline
mRatBN7.21480,867,695 - 80,867,915 (+)MAPPERmRatBN7.2
Rnor_6.01486,231,357 - 86,231,574NCBIRnor6.0
Rnor_5.01486,915,537 - 86,915,754UniSTSRnor5.0
RGSC_v3.41486,655,205 - 86,655,423RGDRGSC3.4
RGSC_v3.41486,655,206 - 86,655,423UniSTSRGSC3.4
RGSC_v3.11486,674,350 - 86,674,568RGD
Celera1479,751,450 - 79,751,667UniSTS
SHRSP x BN Map1444.8999UniSTS
SHRSP x BN Map1444.8999RGD
Cytogenetic Map14q21UniSTS
PMC145549P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21480,933,912 - 80,934,108 (+)MAPPERmRatBN7.2
Rnor_6.01486,297,571 - 86,297,766NCBIRnor6.0
RGSC_v3.41486,721,200 - 86,721,395UniSTSRGSC3.4
Cytogenetic Map14q21UniSTS
BF405463  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21480,845,274 - 80,845,444 (+)MAPPERmRatBN7.2
Rnor_6.01486,208,938 - 86,209,107NCBIRnor6.0
Rnor_5.01486,893,124 - 86,893,293UniSTSRnor5.0
RGSC_v3.41486,632,748 - 86,632,917UniSTSRGSC3.4
Celera1479,729,018 - 79,729,187UniSTS
RH 3.4 Map14575.6UniSTS
Cytogenetic Map14q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 89 88 57 25 57 6 216 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001042354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001042356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_021739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB054054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC110110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF069731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB616255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB692429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB728582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO395982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO406099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M16112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X83375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000067162   ⟹   ENSRNOP00000058882
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1480,845,238 - 80,933,994 (-)Ensembl
Rnor_6.0 Ensembl1486,210,876 - 86,297,623 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000081607   ⟹   ENSRNOP00000068938
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1480,845,238 - 80,933,994 (-)Ensembl
Rnor_6.0 Ensembl1486,208,901 - 86,297,652 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000085265   ⟹   ENSRNOP00000073205
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1480,845,238 - 80,933,994 (-)Ensembl
Rnor_6.0 Ensembl1486,208,901 - 86,297,652 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094612   ⟹   ENSRNOP00000083546
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1480,845,238 - 80,933,994 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095226   ⟹   ENSRNOP00000087316
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1480,845,238 - 80,933,994 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103987   ⟹   ENSRNOP00000088230
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1480,845,238 - 80,933,994 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112062   ⟹   ENSRNOP00000083859
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1480,845,238 - 80,933,994 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116744   ⟹   ENSRNOP00000084286
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1480,845,238 - 80,933,994 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119307   ⟹   ENSRNOP00000093234
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1480,845,238 - 80,933,994 (-)Ensembl
RefSeq Acc Id: NM_001042354   ⟹   NP_001035813
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,059,166 - 85,147,944 (-)NCBI
mRatBN7.21480,845,213 - 80,933,994 (-)NCBI
Rnor_6.01486,208,876 - 86,297,652 (-)NCBI
Rnor_5.01486,893,062 - 86,982,256 (-)NCBI
RGSC_v3.41486,632,686 - 86,721,281 (-)RGD
Celera1479,728,956 - 79,817,594 (-)RGD
Sequence:
RefSeq Acc Id: NM_001042356   ⟹   NP_001035815
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,059,166 - 85,147,944 (-)NCBI
mRatBN7.21480,845,213 - 80,933,994 (-)NCBI
Rnor_6.01486,208,876 - 86,297,652 (-)NCBI
Rnor_5.01486,893,062 - 86,982,256 (-)NCBI
RGSC_v3.41486,632,686 - 86,721,281 (-)RGD
Celera1479,728,956 - 79,817,594 (-)RGD
Sequence:
RefSeq Acc Id: NM_021739   ⟹   NP_068507
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,059,166 - 85,147,944 (-)NCBI
mRatBN7.21480,845,213 - 80,933,994 (-)NCBI
Rnor_6.01486,208,876 - 86,297,652 (-)NCBI
Rnor_5.01486,893,062 - 86,982,256 (-)NCBI
RGSC_v3.41486,632,686 - 86,721,281 (-)RGD
Celera1479,728,956 - 79,817,594 (-)RGD
Sequence:
RefSeq Acc Id: XM_006251170   ⟹   XP_006251232
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,059,166 - 85,148,112 (-)NCBI
mRatBN7.21480,845,206 - 80,934,163 (-)NCBI
Rnor_6.01486,210,851 - 86,297,724 (-)NCBI
Rnor_5.01486,893,062 - 86,982,256 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006251171   ⟹   XP_006251233
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,059,166 - 85,148,114 (-)NCBI
mRatBN7.21480,845,206 - 80,934,166 (-)NCBI
Rnor_6.01486,210,851 - 86,297,724 (-)NCBI
Rnor_5.01486,893,062 - 86,982,256 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006251172   ⟹   XP_006251234
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,059,166 - 85,148,117 (-)NCBI
mRatBN7.21480,845,206 - 80,934,169 (-)NCBI
Rnor_6.01486,210,851 - 86,297,723 (-)NCBI
Rnor_5.01486,893,062 - 86,982,256 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006251174   ⟹   XP_006251236
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,059,166 - 85,148,120 (-)NCBI
mRatBN7.21480,845,206 - 80,934,172 (-)NCBI
Rnor_6.01486,210,851 - 86,297,724 (-)NCBI
Rnor_5.01486,893,062 - 86,982,256 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006251176   ⟹   XP_006251238
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,059,166 - 85,148,099 (-)NCBI
mRatBN7.21480,845,206 - 80,934,150 (-)NCBI
Rnor_6.01486,210,851 - 86,297,719 (-)NCBI
Rnor_5.01486,893,062 - 86,982,256 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006251177   ⟹   XP_006251239
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,059,166 - 85,148,102 (-)NCBI
mRatBN7.21480,845,206 - 80,934,150 (-)NCBI
Rnor_6.01486,210,851 - 86,297,718 (-)NCBI
Rnor_5.01486,893,062 - 86,982,256 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599069   ⟹   XP_017454558
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,059,166 - 85,148,121 (-)NCBI
mRatBN7.21480,845,206 - 80,934,172 (-)NCBI
Rnor_6.01486,210,851 - 86,297,727 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599072   ⟹   XP_017454561
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,059,166 - 85,148,107 (-)NCBI
mRatBN7.21480,845,206 - 80,934,158 (-)NCBI
Rnor_6.01486,210,851 - 86,297,723 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039091616   ⟹   XP_038947544
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,059,166 - 85,148,111 (-)NCBI
mRatBN7.21480,845,206 - 80,934,163 (-)NCBI
RefSeq Acc Id: XM_063272853   ⟹   XP_063128923
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,059,166 - 85,148,109 (-)NCBI
RefSeq Acc Id: XM_063272854   ⟹   XP_063128924
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,059,166 - 85,148,111 (-)NCBI
RefSeq Acc Id: XM_063272855   ⟹   XP_063128925
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,059,166 - 85,148,114 (-)NCBI
RefSeq Acc Id: XM_063272856   ⟹   XP_063128926
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,059,166 - 85,148,118 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001035813 (Get FASTA)   NCBI Sequence Viewer  
  NP_001035815 (Get FASTA)   NCBI Sequence Viewer  
  NP_068507 (Get FASTA)   NCBI Sequence Viewer  
  XP_006251232 (Get FASTA)   NCBI Sequence Viewer  
  XP_006251233 (Get FASTA)   NCBI Sequence Viewer  
  XP_006251234 (Get FASTA)   NCBI Sequence Viewer  
  XP_006251236 (Get FASTA)   NCBI Sequence Viewer  
  XP_006251238 (Get FASTA)   NCBI Sequence Viewer  
  XP_006251239 (Get FASTA)   NCBI Sequence Viewer  
  XP_017454558 (Get FASTA)   NCBI Sequence Viewer  
  XP_017454561 (Get FASTA)   NCBI Sequence Viewer  
  XP_038947544 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128923 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128924 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128925 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128926 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA41866 (Get FASTA)   NCBI Sequence Viewer  
  AAC83644 (Get FASTA)   NCBI Sequence Viewer  
  BAB62715 (Get FASTA)   NCBI Sequence Viewer  
  CAA58289 (Get FASTA)   NCBI Sequence Viewer  
  EDM00329 (Get FASTA)   NCBI Sequence Viewer  
  EDM00330 (Get FASTA)   NCBI Sequence Viewer  
  EDM00331 (Get FASTA)   NCBI Sequence Viewer  
  EDM00332 (Get FASTA)   NCBI Sequence Viewer  
  EDM00333 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000058882.2
  ENSRNOP00000068938.1
  ENSRNOP00000073205.1
  ENSRNOP00000083546.1
  ENSRNOP00000083859.1
  ENSRNOP00000084286.1
  ENSRNOP00000087316.1
  ENSRNOP00000088230.1
  ENSRNOP00000093234.1
GenBank Protein P08413 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_068507   ⟸   NM_021739
- Peptide Label: isoform 2
- UniProtKB: P08413 (UniProtKB/Swiss-Prot),   G3V9G3 (UniProtKB/TrEMBL),   A6IKR8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001035815   ⟸   NM_001042356
- Peptide Label: isoform 3
- UniProtKB: P08413 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001035813   ⟸   NM_001042354
- Peptide Label: isoform 1
- UniProtKB: F1LNI8 (UniProtKB/TrEMBL),   Q63094 (UniProtKB/TrEMBL),   A6IKR6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251236   ⟸   XM_006251174
- Peptide Label: isoform X6
- UniProtKB: A6IKR6 (UniProtKB/TrEMBL),   Q63094 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251239   ⟸   XM_006251177
- Peptide Label: isoform X9
- UniProtKB: P08413 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006251234   ⟸   XM_006251172
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZX82 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251238   ⟸   XM_006251176
- Peptide Label: isoform X8
- UniProtKB: P08413 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006251233   ⟸   XM_006251171
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZX82 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251232   ⟸   XM_006251170
- Peptide Label: isoform X1
- UniProtKB: F1LUE2 (UniProtKB/TrEMBL),   A6IKR9 (UniProtKB/TrEMBL),   A0A8I5ZX82 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454558   ⟸   XM_017599069
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZX82 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454561   ⟸   XM_017599072
- Peptide Label: isoform X10
- UniProtKB: P08413 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000058882   ⟸   ENSRNOT00000067162
Ensembl Acc Id: ENSRNOP00000073205   ⟸   ENSRNOT00000085265
Ensembl Acc Id: ENSRNOP00000068938   ⟸   ENSRNOT00000081607
RefSeq Acc Id: XP_038947544   ⟸   XM_039091616
- Peptide Label: isoform X11
- UniProtKB: P08413 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSRNOP00000084286   ⟸   ENSRNOT00000116744
Ensembl Acc Id: ENSRNOP00000093234   ⟸   ENSRNOT00000119307
Ensembl Acc Id: ENSRNOP00000088230   ⟸   ENSRNOT00000103987
Ensembl Acc Id: ENSRNOP00000087316   ⟸   ENSRNOT00000095226
Ensembl Acc Id: ENSRNOP00000083859   ⟸   ENSRNOT00000112062
Ensembl Acc Id: ENSRNOP00000083546   ⟸   ENSRNOT00000094612
RefSeq Acc Id: XP_063128926   ⟸   XM_063272856
- Peptide Label: isoform X13
- UniProtKB: P08413 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063128925   ⟸   XM_063272855
- Peptide Label: isoform X12
- UniProtKB: P08413 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063128924   ⟸   XM_063272854
- Peptide Label: isoform X7
- UniProtKB: A6IKR6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128923   ⟸   XM_063272853
- Peptide Label: isoform X5
- UniProtKB: A6IKR6 (UniProtKB/TrEMBL)
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P08413-F1-model_v2 AlphaFold P08413 1-542 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699476
Promoter ID:EPDNEW_R9992
Type:initiation region
Name:Camk2b_1
Description:calcium/calmodulin-dependent protein kinase II beta
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01486,297,648 - 86,297,708EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2262 AgrOrtholog
BioCyc Gene G2FUF-15106 BioCyc
Ensembl Genes ENSRNOG00000052080 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000067162.3 UniProtKB/TrEMBL
  ENSRNOT00000081607.2 UniProtKB/TrEMBL
  ENSRNOT00000085265.2 UniProtKB/TrEMBL
  ENSRNOT00000094612.1 UniProtKB/TrEMBL
  ENSRNOT00000095226.1 UniProtKB/TrEMBL
  ENSRNOT00000103987.1 UniProtKB/TrEMBL
  ENSRNOT00000112062.1 UniProtKB/TrEMBL
  ENSRNOT00000116744.1 UniProtKB/TrEMBL
  ENSRNOT00000119307.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.450.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.10.140.620 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ca/CaM-dep_prot_kinase-assoc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NTF2-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24245 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 24245 ENTREZGENE
PANTHER CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT BETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CaMKII_AD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Camk2b PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000052080 RatGTEx
SMART S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54427 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZX82 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZYX1_RAT UniProtKB/TrEMBL
  A0A8I6A024_RAT UniProtKB/TrEMBL
  A0A8I6A445_RAT UniProtKB/TrEMBL
  A0A8I6AIA5_RAT UniProtKB/TrEMBL
  A0A8I6GFZ7_RAT UniProtKB/TrEMBL
  A6IKR6 ENTREZGENE, UniProtKB/TrEMBL
  A6IKR8 ENTREZGENE, UniProtKB/TrEMBL
  A6IKR9 ENTREZGENE, UniProtKB/TrEMBL
  F1LNI8 ENTREZGENE, UniProtKB/TrEMBL
  F1LUE2 ENTREZGENE, UniProtKB/TrEMBL
  G3V9G3 ENTREZGENE, UniProtKB/TrEMBL
  KCC2B_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q63094 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-02-25 Camk2b  calcium/calmodulin-dependent protein kinase II beta  Camk2b  calcium/calmodulin-dependent protein kinase (CaM kinase) II beta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-24 Camk2b  calcium/calmodulin-dependent protein kinase (CaM kinase) II beta  Camk2b  calcium/calmodulin-dependent protein kinase II, beta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Camk2b  calcium/calmodulin-dependent protein kinase II, beta    calcium/calmodulin-dependent protein kinase II beta subunit  Name updated 1299863 APPROVED
2002-11-06 Camk2b  calcium/calmodulin-dependent protein kinase II beta subunit    Ca++/calmodulin-dependent protein kinase II, beta subunit  Name updated 625702 APPROVED
2002-06-10 Camk2b  Ca++/calmodulin-dependent protein kinase II, beta subunit      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_function beta subunit of kinase 634690
gene_process may play a role in the development of the retina 634688
gene_protein 542 amino acid protein 634690