(+)-artemisinin multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 artemisinin inhibits the reaction [PPARGC1A protein results in increased activity of ESRRA protein] CTD PMID:30818834 (+)-catechin affects expression ISO Ppargc1a (Mus musculus) 6480464 Catechin affects the expression of PPARGC1A mRNA CTD PMID:26363153 (+)-catechin multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Quercetin affects the reaction [Catechin affects the expression of PPARGC1A mRNA] CTD PMID:26363153 (+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of PPARGC1A mRNA] CTD PMID:31150632 (+)-taxifolin multiple interactions EXP 6480464 taxifolin inhibits the reaction [Dibutyl Phthalate results in decreased expression of PPARGC1A protein] CTD PMID:32525071 (-)-epigallocatechin 3-gallate multiple interactions EXP 6480464 [1-Methyl-4-phenylpyridinium co-treated with epigallocatechin gallate] results in increased expression of PPARGC1A mRNA and [1-Methyl-4-phenylpyridinium co-treated with epigallocatechin gallate] results in increased expression of PPARGC1A protein CTD PMID:22742579 (-)-epigallocatechin 3-gallate decreases expression ISO Ppargc1a (Mus musculus) 6480464 epigallocatechin gallate results in decreased expression of PPARGC1A protein CTD PMID:29175576 (1->4)-beta-D-glucan multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of PPARGC1A mRNA CTD PMID:36331819 (20S)-ginsenoside Rg3 increases expression EXP 6480464 ginsenoside Rg3 results in increased expression of PPARGC1A mRNA CTD PMID:30144466 (R)-adrenaline increases expression EXP 6480464 Epinephrine results in increased expression of PPARGC1A mRNA CTD PMID:22496244 (R)-carnitine multiple interactions EXP 6480464 Carnitine inhibits the reaction [Methotrexate results in decreased expression of PPARGC1A protein] CTD PMID:37312617 (R)-lipoic acid multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [Acetylcarnitine co-treated with Thioctic Acid] results in increased expression of PPARGC1A protein CTD PMID:20414966 (R)-lipoic acid decreases expression ISO Ppargc1a (Mus musculus) 6480464 Thioctic Acid results in decreased expression of PPARGC1A protein CTD PMID:37739047 (R)-lipoic acid multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Thioctic Acid co-treated with Silicon] results in increased expression of PPARGC1A protein and Thioctic Acid inhibits the reaction [Sodium Fluoride results in decreased expression of PPARGC1A mRNA] CTD PMID:34252510 and PMID:37739047 (R)-lipoic acid multiple interactions EXP 6480464 Thioctic Acid inhibits the reaction [Dietary Fats results in decreased expression of PPARGC1A mRNA] CTD PMID:22464149 (R)-lipoic acid increases expression ISO PPARGC1A (Homo sapiens) 6480464 Thioctic Acid results in increased expression of PPARGC1A protein CTD PMID:20414966 (R)-noradrenaline multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Propranolol co-treated with Prazosin] inhibits the reaction [Norepinephrine results in increased expression of PPARGC1A mRNA] and N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Norepinephrine results in increased expression of PPARGC1A mRNA] CTD PMID:16513826 (R)-noradrenaline multiple interactions EXP 6480464 Norepinephrine inhibits the reaction [Testosterone results in decreased expression of PPARGC1A mRNA] CTD PMID:16954335 (R)-noradrenaline increases expression ISO Ppargc1a (Mus musculus) 6480464 Norepinephrine results in increased expression of PPARGC1A mRNA CTD PMID:16513826 (S)-nicotine multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [BMP7 protein co-treated with INS1 protein co-treated with Triiodothyronine co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with Indomethacin co-treated with Nicotine] affects the expression of PPARGC1A mRNA and [BMP7 protein co-treated with INS1 protein co-treated with Triiodothyronine co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with Indomethacin co-treated with Nicotine] affects the expression of PPARGC1A protein CTD PMID:33091441 (S)-nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of PPARGC1A mRNA and Nicotine results in decreased expression of PPARGC1A protein CTD PMID:29155039 and PMID:33091441 1,1-dichloroethene decreases expression ISO Ppargc1a (Mus musculus) 6480464 vinylidene chloride results in decreased expression of PPARGC1A mRNA CTD PMID:26682919 1,2-dimethylhydrazine decreases expression ISO Ppargc1a (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of PPARGC1A mRNA CTD PMID:22206623 1,4-dithiothreitol increases expression ISO PPARGC1A (Homo sapiens) 6480464 Dithiothreitol results in increased expression of PPARGC1A mRNA CTD PMID:23056435 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expression ISO Ppargc1a (Mus musculus) 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:30236862 1-stearoyl-2-arachidonoyl-sn-glycerol increases expression ISO PPARGC1A (Homo sapiens) 6480464 1-stearoyl-2-arachidonoylglycerol results in increased expression of PPARGC1A mRNA CTD PMID:23056435 11-deoxycorticosterone increases expression ISO PPARGC1A (Homo sapiens) 6480464 Desoxycorticosterone results in increased expression of PPARGC1A mRNA CTD PMID:23056435 17alpha-ethynylestradiol decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Ethinyl Estradiol results in decreased expression of PPARGC1A mRNA CTD PMID:18936297 17beta-estradiol multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of PPARGC1A mRNA more ... CTD PMID:17404688 more ... 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of PPARGC1A mRNA CTD PMID:32145629 17beta-estradiol multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Estradiol promotes the reaction [PPARGC1A protein binds to CYP2B10 promoter] CTD PMID:23684557 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of PPARGC1A mRNA CTD PMID:23056435 17beta-estradiol increases expression ISO PPARGC1A (Homo sapiens) 6480464 Estradiol results in increased expression of PPARGC1A mRNA CTD PMID:21632981 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to PPARGC1A protein modified form] CTD PMID:28751236 1D-myo-inositol 1-phosphate increases expression ISO PPARGC1A (Homo sapiens) 6480464 inositol 1-phosphate results in increased expression of PPARGC1A mRNA CTD PMID:23056435 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 1H-(1 more ... CTD PMID:24041027 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one multiple interactions EXP 6480464 1H-(1 more ... CTD PMID:17179207 1H-pyrazole decreases expression ISO Ppargc1a (Mus musculus) 6480464 pyrazole results in decreased expression of PPARGC1A mRNA CTD PMID:17945193 2,2',4,4'-Tetrabromodiphenyl ether decreases expression EXP 6480464 2 more ... CTD PMID:36269211 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions EXP 6480464 MIR128-1 promotes the reaction [2 more ... CTD PMID:36269211 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO PPARGC1A (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of PPARGC1A mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Ppargc1a (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of PPARGC1A protein CTD PMID:32044341 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of PPARGC1A mRNA CTD PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Ppargc1a (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of PPARGC1A mRNA CTD PMID:21570461 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of PPARGC1A mRNA CTD PMID:20106945 and PMID:21632981 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of PPARGC1A mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Ppargc1a (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of PPARGC1A mRNA CTD PMID:21846477 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Ppargc1a (Mus musculus) 6480464 NFE2L2 gene mutant form inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PPARGC1A mRNA] more ... CTD PMID:21846477 and PMID:32044341 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA] more ... CTD PMID:20165829 2-amino-2-deoxy-D-glucopyranose decreases expression EXP 6480464 Glucosamine results in decreased expression of PPARGC1A mRNA and Glucosamine results in decreased expression of PPARGC1A protein CTD PMID:20165829 2-amino-2-deoxy-D-glucopyranose multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA] more ... CTD PMID:20165829 2-amino-2-deoxy-D-glucopyranose decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Glucosamine results in decreased expression of PPARGC1A mRNA and Glucosamine results in decreased expression of PPARGC1A protein CTD PMID:20165829 2-butoxyethanol increases expression ISO Ppargc1a (Mus musculus) 6480464 n-butoxyethanol results in increased expression of PPARGC1A mRNA CTD PMID:19812364 2-chloroethanol multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Ethylene Chlorohydrin co-treated with Lipopolysaccharides] results in increased expression of PPARGC1A mRNA and Sirolimus inhibits the reaction [[Ethylene Chlorohydrin co-treated with Lipopolysaccharides] results in increased expression of PPARGC1A mRNA] CTD PMID:31499194 3',5'-cyclic AMP multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Cyclic AMP promotes the reaction [PPARGC1A protein binds to CYP2A5 promoter] more ... CTD PMID:18602936 and PMID:22117073 3',5'-cyclic AMP multiple interactions EXP 6480464 [Dexamethasone co-treated with Cyclic AMP] results in increased expression of PPARGC1A mRNA more ... CTD PMID:22676303 3',5'-cyclic AMP increases expression ISO Ppargc1a (Mus musculus) 6480464 Cyclic AMP results in increased expression of PPARGC1A mRNA CTD PMID:18602936 and PMID:22117073 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:27509375 3,3',4,4',5-pentachlorobiphenyl affects expression ISO Ppargc1a (Mus musculus) 6480464 3 more ... CTD PMID:37080397 3,3',5-triiodo-L-thyronine multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [BMP7 protein co-treated with INS1 protein co-treated with Triiodothyronine co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with Indomethacin co-treated with Nicotine] affects the expression of PPARGC1A mRNA and [BMP7 protein co-treated with INS1 protein co-treated with Triiodothyronine co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with Indomethacin co-treated with Nicotine] affects the expression of PPARGC1A protein CTD PMID:33091441 3,3',5-triiodo-L-thyronine increases expression ISO Ppargc1a (Mus musculus) 6480464 Triiodothyronine results in increased expression of PPARGC1A mRNA CTD PMID:30209975 3,3',5-triiodo-L-thyronine increases expression EXP 6480464 Triiodothyronine results in increased expression of PPARGC1A mRNA CTD PMID:23209300 3,3',5-triiodo-L-thyronine multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of PPARGC1A mRNA and Rosmarinic Acid affects the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of PPARGC1A mRNA] CTD PMID:33476690 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with Rosiglitazone co-treated with 4 more ... CTD PMID:28628672 more ... 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [BMP7 protein co-treated with INS1 protein co-treated with Triiodothyronine co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with Indomethacin co-treated with Nicotine] affects the expression of PPARGC1A mRNA more ... CTD PMID:29288687 more ... 4,4'-sulfonyldiphenol increases expression ISO Ppargc1a (Mus musculus) 6480464 bisphenol S results in increased expression of PPARGC1A mRNA CTD PMID:25111128 and PMID:30951980 4,4'-sulfonyldiphenol decreases methylation ISO PPARGC1A (Homo sapiens) 6480464 bisphenol S results in decreased methylation of PPARGC1A gene CTD PMID:31601247 4,4'-sulfonyldiphenol increases expression ISO PPARGC1A (Homo sapiens) 6480464 bisphenol S results in increased expression of PPARGC1A mRNA CTD PMID:30616060 4,4'-sulfonyldiphenol multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [bisphenol S co-treated with Fulvestrant] results in increased methylation of PPARGC1A gene more ... CTD PMID:28628672 more ... 4,6-dioxoheptanoic acid increases expression ISO Ppargc1a (Mus musculus) 6480464 succinylacetone results in increased expression of PPARGC1A mRNA CTD PMID:22859313 4-hydroxyphenyl retinamide increases expression ISO Ppargc1a (Mus musculus) 6480464 Fenretinide results in increased expression of PPARGC1A mRNA CTD PMID:28973697 4-phenylbutyric acid multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA] and 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein] CTD PMID:20165829 4-phenylbutyric acid multiple interactions ISO Ppargc1a (Mus musculus) 6480464 4-phenylbutyric acid inhibits the reaction [Glucose results in decreased expression of PPARGC1A mRNA] CTD PMID:28482072 4-phenylbutyric acid multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA] and 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein] CTD PMID:20165829 5-(2-chloroethyl)-4-methylthiazole multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Chlormethiazole affects the reaction [Ethanol results in decreased expression of PPARGC1A mRNA] and Chlormethiazole inhibits the reaction [Ethanol results in decreased acetylation of PPARGC1A protein] CTD PMID:24892905 5-aminoimidazole-4-carboxamide multiple interactions EXP 6480464 [Aminoimidazole Carboxamide analog co-treated with Lipopolysaccharides] results in increased expression of PPARGC1A protein more ... CTD PMID:19853624 5-aza-2'-deoxycytidine decreases methylation ISO Ppargc1a (Mus musculus) 6480464 Decitabine results in decreased methylation of PPARGC1A gene CTD PMID:27923600 5-methyl-4-oxido-2-pyrazin-4-iumcarboxylic acid increases expression ISO PPARGC1A (Homo sapiens) 6480464 acipimox results in increased expression of PPARGC1A mRNA CTD PMID:25352640 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions EXP 6480464 6-chloro-2 more ... CTD PMID:33661552 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions ISO Ppargc1a (Mus musculus) 6480464 6-chloro-2 more ... CTD PMID:34738708 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 6-chloro-2 more ... CTD PMID:33957017 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of PPARGC1A mRNA CTD PMID:24780913 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of PPARGC1A mRNA CTD PMID:30047161 8-bromo-3',5'-cyclic GMP increases expression ISO PPARGC1A (Homo sapiens) 6480464 8-bromocyclic GMP results in increased expression of PPARGC1A mRNA CTD PMID:24041027 8-bromo-3',5'-cyclic GMP multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 tin protoporphyrin IX inhibits the reaction [8-bromocyclic GMP results in increased expression of PPARGC1A mRNA] CTD PMID:24041027 9-cis-retinoic acid multiple interactions ISO Ppargc1a (Mus musculus) 6480464 2-chloro-5-nitrobenzanilide inhibits the reaction [Alitretinoin results in increased expression of PPARGC1A mRNA] more ... CTD PMID:16513826 9-cis-retinoic acid increases expression ISO Ppargc1a (Mus musculus) 6480464 Alitretinoin results in increased expression of PPARGC1A mRNA CTD PMID:16513826 9-cis-retinoic acid increases expression ISO PPARGC1A (Homo sapiens) 6480464 Alitretinoin results in increased expression of PPARGC1A mRNA CTD PMID:16513826 acadesine multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 acadesine inhibits the reaction [Isoniazid results in decreased expression of PPARGC1A protein] CTD PMID:28556920 acadesine multiple interactions EXP 6480464 Dietary Fats promotes the reaction [acadesine results in increased expression of PPARGC1A mRNA] CTD PMID:22496244 acadesine increases expression EXP 6480464 acadesine results in increased expression of PPARGC1A mRNA CTD PMID:22496244 acadesine increases expression ISO PPARGC1A (Homo sapiens) 6480464 acadesine results in increased expression of PPARGC1A protein CTD PMID:28556920 acarbose affects response to substance ISO PPARGC1A (Homo sapiens) 6480464 PPARGC1A protein polymorphism affects the susceptibility to Acarbose CTD PMID:15592662 acetamide increases expression EXP 6480464 acetamide results in increased expression of PPARGC1A mRNA CTD PMID:31881176 acetic acid decreases expression EXP 6480464 Acetic Acid results in decreased expression of PPARGC1A mRNA CTD PMID:35122774 acetic acid multiple interactions EXP 6480464 Linagliptin inhibits the reaction [Acetic Acid results in decreased expression of PPARGC1A mRNA] and Mesalamine inhibits the reaction [Acetic Acid results in decreased expression of PPARGC1A mRNA] CTD PMID:35122774 acetylsalicylic acid multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Aspirin inhibits the reaction [Cisplatin results in decreased expression of PPARGC1A mRNA] CTD PMID:37179038 acrolein decreases expression EXP 6480464 Acrolein results in decreased expression of PPARGC1A mRNA and Acrolein results in decreased expression of PPARGC1A protein CTD PMID:35150775 acrylamide increases expression ISO PPARGC1A (Homo sapiens) 6480464 Acrylamide results in increased expression of PPARGC1A mRNA CTD PMID:32763439 adenosine increases expression ISO PPARGC1A (Homo sapiens) 6480464 Adenosine results in increased expression of PPARGC1A mRNA CTD PMID:23056435 adenosine 5'-monophosphate increases expression ISO PPARGC1A (Homo sapiens) 6480464 Adenosine Monophosphate results in increased expression of PPARGC1A mRNA CTD PMID:23056435 afimoxifene multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 afimoxifene inhibits the reaction [PPARGC1A protein binds to ESRRG protein] CTD PMID:16889744 aflatoxin B1 affects expression ISO PPARGC1A (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of PPARGC1A protein CTD PMID:20106945 aflatoxin B1 decreases methylation ISO PPARGC1A (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of PPARGC1A gene CTD PMID:27153756 aflatoxin B1 decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of PPARGC1A mRNA CTD PMID:21632981 and PMID:22100608 Aflatoxin B2 alpha increases methylation ISO PPARGC1A (Homo sapiens) 6480464 aflatoxin B2 results in increased methylation of PPARGC1A intron CTD PMID:30157460 AICA ribonucleotide multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 AICA ribonucleotide inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of PPARGC1A protein] CTD PMID:25522270 AICA ribonucleotide increases expression EXP 6480464 AICA ribonucleotide results in increased expression of PPARGC1A mRNA CTD PMID:20438809 AICA ribonucleotide multiple interactions EXP 6480464 dorsomorphin inhibits the reaction [AICA ribonucleotide results in increased expression of PPARGC1A mRNA] CTD PMID:20438809 AICA ribonucleotide decreases expression ISO Ppargc1a (Mus musculus) 6480464 AICA ribonucleotide results in decreased expression of PPARGC1A mRNA CTD PMID:24428821 AICA ribonucleotide multiple interactions ISO Ppargc1a (Mus musculus) 6480464 AICA ribonucleotide inhibits the reaction [Glucose results in decreased expression of PPARGC1A protein] and dorsomorphin promotes the reaction [AICA ribonucleotide results in decreased expression of PPARGC1A mRNA] CTD PMID:23090186 and PMID:24428821 albuterol increases expression ISO Ppargc1a (Mus musculus) 6480464 Albuterol results in increased expression of PPARGC1A mRNA CTD PMID:17446185 aldehydo-D-glucosamine multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA] more ... CTD PMID:20165829 aldehydo-D-glucosamine decreases expression EXP 6480464 Glucosamine results in decreased expression of PPARGC1A mRNA and Glucosamine results in decreased expression of PPARGC1A protein CTD PMID:20165829 aldehydo-D-glucosamine multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA] more ... CTD PMID:20165829 aldehydo-D-glucosamine decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Glucosamine results in decreased expression of PPARGC1A mRNA and Glucosamine results in decreased expression of PPARGC1A protein CTD PMID:20165829 aldehydo-D-glucose decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Glucose deficiency results in decreased expression of PPARGC1A mRNA more ... CTD PMID:17855661 more ... aldehydo-D-glucose multiple interactions EXP 6480464 Inositol inhibits the reaction [Glucose results in decreased expression of PPARGC1A protein] and SRT1720 inhibits the reaction [Glucose results in decreased expression of PPARGC1A protein] CTD PMID:31639451 and PMID:35243728 aldehydo-D-glucose increases expression ISO PPARGC1A (Homo sapiens) 6480464 Glucose deficiency results in increased expression of PPARGC1A mRNA and Glucose results in increased expression of PPARGC1A mRNA CTD PMID:26811028 and PMID:33962019 aldehydo-D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of PPARGC1A protein CTD PMID:31639451 and PMID:35243728 aldehydo-D-glucose affects expression EXP 6480464 Glucose affects the expression of PPARGC1A mRNA CTD PMID:24349266 aldehydo-D-glucose increases acetylation ISO PPARGC1A (Homo sapiens) 6480464 Glucose results in increased acetylation of PPARGC1A protein CTD PMID:19071085 aldehydo-D-glucose decreases expression ISO Ppargc1a (Mus musculus) 6480464 Glucose results in decreased expression of PPARGC1A mRNA and Glucose results in decreased expression of PPARGC1A protein CTD PMID:23090186 more ... aldehydo-D-glucose multiple interactions ISO Ppargc1a (Mus musculus) 6480464 4-phenylbutyric acid inhibits the reaction [Glucose results in decreased expression of PPARGC1A mRNA] more ... CTD PMID:23090186 more ... aldehydo-D-glucose multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 6-chloro-2 more ... CTD PMID:17855661 more ... aldosterone increases expression EXP 6480464 Aldosterone results in increased expression of PPARGC1A mRNA CTD PMID:19808358 all-trans-retinal increases expression ISO PPARGC1A (Homo sapiens) 6480464 Retinaldehyde results in increased expression of PPARGC1A mRNA CTD PMID:23056435 all-trans-retinoic acid increases expression ISO Ppargc1a (Mus musculus) 6480464 Tretinoin results in increased expression of PPARGC1A mRNA CTD PMID:16840543 all-trans-retinol multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Vitamin A affects the reaction [PPARGC1A protein binds to PCK1 promoter] CTD PMID:16317119 alloxan multiple interactions EXP 6480464 imisopasem manganese inhibits the reaction [Alloxan results in decreased expression of PPARGC1A protein] CTD PMID:28483572 alloxan decreases expression EXP 6480464 Alloxan results in decreased expression of PPARGC1A protein CTD PMID:28483572 allyl isothiocyanate multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 allyl isothiocyanate inhibits the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA] and allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]] CTD PMID:25069801 alpha,alpha-trehalose increases expression ISO Ppargc1a (Mus musculus) 6480464 Trehalose results in increased expression of PPARGC1A mRNA CTD PMID:30335591 alpha,alpha-trehalose multiple interactions ISO Ppargc1a (Mus musculus) 6480464 TFEB affects the reaction [Trehalose results in increased expression of PPARGC1A mRNA] CTD PMID:30335591 alpha-D-galactose decreases expression EXP 6480464 Galactose results in decreased expression of PPARGC1A protein CTD PMID:28302704 aminoguanidine multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Pyruvaldehyde co-treated with pimagedine] results in increased expression of PPARGC1A protein CTD PMID:26723916 aminoguanidine multiple interactions EXP 6480464 [pimagedine co-treated with Pyruvaldehyde] results in increased expression of PPARGC1A protein CTD PMID:28919305 amiodarone increases expression ISO PPARGC1A (Homo sapiens) 6480464 Amiodarone results in increased expression of PPARGC1A mRNA CTD PMID:27089845 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of PPARGC1A mRNA CTD PMID:16483693 angiotensin II decreases expression EXP 6480464 Angiotensin II results in decreased expression of PPARGC1A protein CTD PMID:37269933 angiotensin II multiple interactions EXP 6480464 celastrol methyl ester inhibits the reaction [Angiotensin II results in decreased expression of PPARGC1A protein] CTD PMID:37269933 Ankaflavin increases expression ISO Ppargc1a (Mus musculus) 6480464 ankaflavin results in increased expression of PPARGC1A mRNA CTD PMID:24275089 anthra[1,9-cd]pyrazol-6(2H)-one increases expression ISO Ppargc1a (Mus musculus) 6480464 pyrazolanthrone results in increased expression of PPARGC1A mRNA CTD PMID:21873422 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO Ppargc1a (Mus musculus) 6480464 6 more ... CTD PMID:21873422 and PMID:31447676 antimycin A decreases expression ISO Ppargc1a (Mus musculus) 6480464 Antimycin A results in decreased expression of PPARGC1A protein CTD PMID:34302933 arachidonyl-2'-chloroethylamide multiple interactions ISO Ppargc1a (Mus musculus) 6480464 FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide results in decreased expression of PPARGC1A mRNA] CTD PMID:26847930 arachidonyl-2'-chloroethylamide decreases expression ISO Ppargc1a (Mus musculus) 6480464 arachidonyl-2-chloroethylamide results in decreased expression of PPARGC1A mRNA CTD PMID:26847930 aristolochic acid A decreases expression ISO PPARGC1A (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of PPARGC1A mRNA CTD PMID:33212167 arsane increases expression ISO PPARGC1A (Homo sapiens) 6480464 Arsenic results in increased expression of PPARGC1A mRNA and Arsenic results in increased expression of PPARGC1A protein CTD PMID:21514422 arsane multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of PPARGC1A protein CTD PMID:32045263 arsenic atom increases expression ISO PPARGC1A (Homo sapiens) 6480464 Arsenic results in increased expression of PPARGC1A mRNA and Arsenic results in increased expression of PPARGC1A protein CTD PMID:21514422 arsenic atom multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of PPARGC1A protein CTD PMID:32045263 arsenous acid multiple interactions EXP 6480464 salvianolic acid A inhibits the reaction [Arsenic Trioxide results in decreased expression of PPARGC1A protein] CTD PMID:29867492 arsenous acid multiple interactions ISO Ppargc1a (Mus musculus) 6480464 salvianolic acid A inhibits the reaction [Arsenic Trioxide results in decreased expression of PPARGC1A protein] and Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of PPARGC1A mRNA] CTD PMID:29867492 and PMID:30362509 arsenous acid increases expression ISO Ppargc1a (Mus musculus) 6480464 Arsenic Trioxide results in increased expression of PPARGC1A mRNA CTD PMID:30362509 arsenous acid decreases expression ISO Ppargc1a (Mus musculus) 6480464 Arsenic Trioxide results in decreased expression of PPARGC1A protein CTD PMID:29867492 arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of PPARGC1A protein CTD PMID:29867492 arsenous acid increases expression ISO PPARGC1A (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of PPARGC1A mRNA CTD PMID:20458559 asiatic acid multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [Glutamic Acid co-treated with asiatic acid] results in increased expression of PPARGC1A protein CTD PMID:22447225 aspartame multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Fats more ... CTD PMID:23783067 atorvastatin calcium multiple interactions EXP 6480464 [Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of PPARGC1A protein] more ... CTD PMID:21775390 more ... atorvastatin calcium affects expression ISO Ppargc1a (Mus musculus) 6480464 Atorvastatin affects the expression of PPARGC1A mRNA CTD PMID:30511338 atorvastatin calcium decreases expression ISO Ppargc1a (Mus musculus) 6480464 Atorvastatin results in decreased expression of PPARGC1A protein CTD PMID:30511338 atorvastatin calcium multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of PPARGC1A mRNA CTD PMID:30511338 atorvastatin calcium decreases expression EXP 6480464 Atorvastatin results in decreased expression of PPARGC1A mRNA CTD PMID:21775390 atorvastatin calcium increases expression EXP 6480464 Atorvastatin results in increased expression of PPARGC1A mRNA CTD PMID:21775390 atrazine increases expression EXP 6480464 Atrazine results in increased expression of PPARGC1A mRNA CTD PMID:27114639 atrazine decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Atrazine results in decreased expression of PPARGC1A mRNA CTD PMID:22378314 and PMID:27114639 benfotiamine multiple interactions ISO Ppargc1a (Mus musculus) 6480464 benphothiamine inhibits the reaction [MAPT protein results in decreased expression of PPARGC1A protein] CTD PMID:29860433 benzo[a]pyrene decreases expression ISO Ppargc1a (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of PPARGC1A mRNA CTD PMID:19770486 benzo[a]pyrene affects expression EXP 6480464 Benzo(a)pyrene affects the expression of PPARGC1A mRNA CTD PMID:32619457 benzo[a]pyrene multiple interactions EXP 6480464 Benzo(a)pyrene affects the expression of and affects the phosphorylation of PPARGC1A protein more ... CTD PMID:32619457 benzo[a]pyrene decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of PPARGC1A mRNA CTD PMID:20106945 and PMID:21632981 benzo[a]pyrene diol epoxide I increases expression ISO PPARGC1A (Homo sapiens) 6480464 7 more ... CTD PMID:26238291 Benzo[ghi]perylene increases expression ISO Ppargc1a (Mus musculus) 6480464 1 and 12-benzoperylene results in increased expression of PPARGC1A mRNA CTD PMID:26377693 berberine multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Berberine inhibits the reaction [Ethanol results in decreased expression of PPARGC1A mRNA] CTD PMID:25455889 beta-D-glucosamine multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA] more ... CTD PMID:20165829 beta-D-glucosamine decreases expression EXP 6480464 Glucosamine results in decreased expression of PPARGC1A mRNA and Glucosamine results in decreased expression of PPARGC1A protein CTD PMID:20165829 beta-D-glucosamine multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA] more ... CTD PMID:20165829 beta-D-glucosamine decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Glucosamine results in decreased expression of PPARGC1A mRNA and Glucosamine results in decreased expression of PPARGC1A protein CTD PMID:20165829 Betanin multiple interactions EXP 6480464 6-chloro-2 more ... CTD PMID:33661552 bezafibrate increases expression ISO Ppargc1a (Mus musculus) 6480464 Bezafibrate results in increased expression of PPARGC1A mRNA CTD PMID:17275789 biotin increases expression ISO PPARGC1A (Homo sapiens) 6480464 Biotin results in increased expression of PPARGC1A mRNA CTD PMID:23056435 bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of PPARGC1A mRNA CTD PMID:22672789 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [Diethylhexyl Phthalate co-treated with Dietary Fats] results in increased expression of PPARGC1A mRNA CTD PMID:33166671 bis(2-ethylhexyl) phthalate multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in decreased expression of PPARGC1A mRNA CTD PMID:37021957 bis(2-ethylhexyl) phthalate decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Diethylhexyl Phthalate results in decreased expression of PPARGC1A mRNA and Diethylhexyl Phthalate results in decreased expression of PPARGC1A protein CTD PMID:34822940 bis(2-ethylhexyl) phthalate increases expression ISO Ppargc1a (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of PPARGC1A mRNA CTD PMID:32522588 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of PPARGC1A gene CTD PMID:25572651 bisphenol A increases expression ISO Ppargc1a (Mus musculus) 6480464 bisphenol A results in increased expression of PPARGC1A mRNA CTD PMID:35479511 bisphenol A decreases methylation ISO PPARGC1A (Homo sapiens) 6480464 bisphenol A results in decreased methylation of PPARGC1A gene CTD PMID:31601247 bisphenol A multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of PPARGC1A protein] and lithospermate B inhibits the reaction [bisphenol A results in decreased expression of PPARGC1A protein] CTD PMID:30641872 and PMID:34165232 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of PPARGC1A mRNA CTD PMID:32145629 bisphenol A multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [bisphenol A binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to PPARGC1A protein modified form] more ... CTD PMID:28751236 more ... bisphenol A decreases expression ISO Ppargc1a (Mus musculus) 6480464 bisphenol A results in decreased expression of PPARGC1A mRNA CTD PMID:27145005 bisphenol A decreases expression EXP 6480464 bisphenol A analog results in decreased expression of PPARGC1A protein more ... CTD PMID:24105817 more ... bisphenol F decreases expression EXP 6480464 bisphenol F results in decreased expression of PPARGC1A protein CTD PMID:35803362 bortezomib multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 Bortezomib inhibits the reaction [PPARGC1A protein results in increased activity of ESRRA protein] CTD PMID:30818834 bosentan decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Bosentan results in decreased expression of PPARGC1A mRNA CTD PMID:29761207 bromobenzene increases expression EXP 6480464 bromobenzene results in increased expression of PPARGC1A mRNA CTD PMID:32479839 bucladesine increases expression ISO Ppargc1a (Mus musculus) 6480464 Bucladesine results in increased expression of PPARGC1A mRNA and Bucladesine results in increased expression of PPARGC1A protein CTD PMID:24428821 and PMID:26064446 bucladesine multiple interactions ISO Ppargc1a (Mus musculus) 6480464 IL22 protein inhibits the reaction [Bucladesine results in increased expression of PPARGC1A protein] and Metformin inhibits the reaction [Bucladesine results in increased expression of PPARGC1A mRNA] CTD PMID:24428821 and PMID:26064446 bupivacaine decreases expression ISO Ppargc1a (Mus musculus) 6480464 Bupivacaine results in decreased expression of PPARGC1A protein CTD PMID:34793778 bupivacaine increases expression ISO Ppargc1a (Mus musculus) 6480464 Bupivacaine results in increased expression of PPARGC1A mRNA CTD PMID:34793778 bupivacaine multiple interactions ISO Ppargc1a (Mus musculus) 6480464 HSPA12A protein inhibits the reaction [Bupivacaine results in decreased expression of PPARGC1A protein] CTD PMID:34793778 buta-1,3-diene decreases expression ISO Ppargc1a (Mus musculus) 6480464 1 and 3-butadiene results in decreased expression of PPARGC1A mRNA CTD PMID:29038090 butan-1-ol multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of PPARGC1A mRNA CTD PMID:29432896 butan-2-one increases expression ISO PPARGC1A (Homo sapiens) 6480464 methylethyl ketone results in increased expression of PPARGC1A mRNA CTD PMID:33064461 butanal decreases expression ISO PPARGC1A (Homo sapiens) 6480464 butyraldehyde results in decreased expression of PPARGC1A mRNA CTD PMID:26079696 Butylbenzyl phthalate decreases expression ISO PPARGC1A (Homo sapiens) 6480464 butylbenzyl phthalate results in decreased expression of PPARGC1A mRNA CTD PMID:26520405 Butylbenzyl phthalate multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in decreased expression of PPARGC1A mRNA CTD PMID:37021957 Butylbenzyl phthalate affects expression ISO Ppargc1a (Mus musculus) 6480464 butylbenzyl phthalate affects the expression of PPARGC1A mRNA CTD PMID:27923775 C60 fullerene decreases expression EXP 6480464 fullerene C60 results in decreased expression of PPARGC1A mRNA CTD PMID:19167457 cadmium atom increases acetylation ISO PPARGC1A (Homo sapiens) 6480464 Cadmium results in increased acetylation of PPARGC1A protein CTD PMID:25159133 cadmium atom increases expression ISO Ppargc1a (Mus musculus) 6480464 Cadmium results in increased expression of PPARGC1A mRNA CTD PMID:26187450 cadmium atom multiple interactions EXP 6480464 [cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of PPARGC1A protein and puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of PPARGC1A protein] CTD PMID:33404196 cadmium atom multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PPARGC1A mRNA more ... CTD PMID:25159133 and PMID:35301059 cadmium dichloride increases acetylation ISO PPARGC1A (Homo sapiens) 6480464 Cadmium Chloride results in increased acetylation of PPARGC1A protein CTD PMID:25159133 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of PPARGC1A mRNA and Cadmium Chloride results in decreased expression of PPARGC1A protein CTD PMID:36493885 cadmium dichloride multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PPARGC1A mRNA] more ... CTD PMID:36493885 cadmium dichloride increases expression ISO PPARGC1A (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of PPARGC1A protein CTD PMID:25809595 cadmium dichloride increases methylation EXP 6480464 Cadmium Chloride results in increased methylation of PPARGC1A promoter CTD PMID:22457795 cadmium dichloride multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PPARGC1A mRNA more ... CTD PMID:25159133 and PMID:35301059 caffeine increases expression EXP 6480464 Caffeine results in increased expression of PPARGC1A mRNA CTD PMID:17516843 calcitriol multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [Calcitriol binds to and results in increased activity of VDR protein] promotes the reaction [VDR protein binds to PPARGC1A protein] more ... CTD PMID:19106115 and PMID:20371703 calcitriol increases expression EXP 6480464 Calcitriol results in increased expression of PPARGC1A protein CTD PMID:30194976 calcitriol multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Calcitriol results in increased expression of PPARGC1A protein] CTD PMID:30194976 calycosin multiple interactions EXP 6480464 7 more ... CTD PMID:36195188 and PMID:36436616 cannabidiol multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Cannabidiol co-treated with Haloperidol] results in increased expression of PPARGC1A protein CTD PMID:30217539 capsaicin increases expression ISO Ppargc1a (Mus musculus) 6480464 Capsaicin results in increased expression of PPARGC1A mRNA CTD PMID:19798065 capsaicin multiple interactions EXP 6480464 Capsaicin promotes the reaction [Dietary Fats results in increased expression of PPARGC1A mRNA] CTD PMID:20359164 captan decreases expression ISO Ppargc1a (Mus musculus) 6480464 Captan results in decreased expression of PPARGC1A mRNA CTD PMID:31558096 carbamazepine affects expression ISO PPARGC1A (Homo sapiens) 6480464 Carbamazepine affects the expression of PPARGC1A mRNA CTD PMID:24752500 carbon monoxide increases expression ISO Ppargc1a (Mus musculus) 6480464 Carbon Monoxide results in increased expression of PPARGC1A mRNA CTD PMID:17179207 carbon monoxide increases expression EXP 6480464 Carbon Monoxide results in increased expression of PPARGC1A protein CTD PMID:17179207 carbon monoxide multiple interactions EXP 6480464 1H-(1 more ... CTD PMID:17179207 carbon nanotube decreases expression ISO Ppargc1a (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 and PMID:32976959 carfilzomib multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 carfilzomib inhibits the reaction [PPARGC1A protein results in increased activity of ESRRA protein] CTD PMID:30818834 carvedilol increases expression EXP 6480464 carvedilol results in increased expression of PPARGC1A mRNA CTD PMID:18971572 casticin decreases expression ISO Ppargc1a (Mus musculus) 6480464 casticin results in decreased expression of PPARGC1A mRNA CTD PMID:28444820 CGP 52608 multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to PPARGC1A gene] CTD PMID:28238834 chicoric acid increases expression EXP 6480464 chicoric acid results in increased expression of PPARGC1A mRNA CTD PMID:24244361 CHIR 99021 multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Chir 99021 promotes the reaction [GSK3B protein affects the expression of PPARGC1A protein] CTD PMID:29883716 CHIR 99021 increases expression ISO Ppargc1a (Mus musculus) 6480464 Chir 99021 results in increased expression of PPARGC1A mRNA and Chir 99021 results in increased expression of PPARGC1A protein CTD PMID:29883716 chitosan increases expression ISO PPARGC1A (Homo sapiens) 6480464 Chitosan results in increased expression of PPARGC1A mRNA CTD PMID:36706893 chlormidazole multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 chlormidazole inhibits the reaction [PPARGC1A protein results in increased activity of ESRRA protein] CTD PMID:30818834 chloroprene increases expression ISO Ppargc1a (Mus musculus) 6480464 Chloroprene results in increased expression of PPARGC1A mRNA CTD PMID:23125180 chlorpyrifos decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Chlorpyrifos results in decreased expression of PPARGC1A mRNA and Chlorpyrifos results in decreased expression of PPARGC1A protein CTD PMID:30835941 chlorpyrifos decreases expression EXP 6480464 Chlorpyrifos results in decreased expression of PPARGC1A mRNA CTD PMID:33586219 and PMID:34060014 chlorpyrifos multiple interactions EXP 6480464 Chlorpyrifos promotes the reaction [iprodione results in decreased expression of PPARGC1A mRNA] and iprodione promotes the reaction [Chlorpyrifos results in decreased expression of PPARGC1A mRNA] CTD PMID:33586219 and PMID:34060014 chlorpyrifos multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 SIRT1 protein inhibits the reaction [Chlorpyrifos results in decreased expression of PPARGC1A mRNA] and SIRT1 protein inhibits the reaction [Chlorpyrifos results in decreased expression of PPARGC1A protein] CTD PMID:30835941 cholate multiple interactions EXP 6480464 [cocoa butter co-treated with Cholesterol and Dietary co-treated with Cholates] results in increased expression of PPARGC1A mRNA CTD PMID:25814186 choline increases expression ISO PPARGC1A (Homo sapiens) 6480464 Choline results in increased expression of PPARGC1A mRNA CTD PMID:23056435 chromium(6+) affects expression ISO Ppargc1a (Mus musculus) 6480464 chromium hexavalent ion affects the expression of PPARGC1A mRNA CTD PMID:28472532 chromium(6+) multiple interactions EXP 6480464 [Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in decreased expression of PPARGC1A mRNA and [Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in decreased expression of PPARGC1A protein CTD PMID:36849043 ciglitazone increases expression ISO Ppargc1a (Mus musculus) 6480464 ciglitazone results in increased expression of PPARGC1A mRNA CTD PMID:16513826 ciglitazone multiple interactions ISO Ppargc1a (Mus musculus) 6480464 PPARG protein promotes the reaction [ciglitazone results in increased expression of PPARGC1A mRNA] CTD PMID:16513826 ciguatoxin CTX1B affects expression ISO Ppargc1a (Mus musculus) 6480464 Ciguatoxins affects the expression of PPARGC1A mRNA CTD PMID:18353800 cisplatin increases acetylation EXP 6480464 Cisplatin results in increased acetylation of PPARGC1A protein CTD PMID:33661552 cisplatin multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [NNT protein inhibits the reaction [NNT protein modified form results in decreased susceptibility to Cisplatin]] which results in decreased expression of PPARGC1A mRNA more ... CTD PMID:36336710 and PMID:37497868 cisplatin multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Aspirin inhibits the reaction [Cisplatin results in decreased expression of PPARGC1A mRNA] more ... CTD PMID:32567747 more ... cisplatin decreases expression ISO Ppargc1a (Mus musculus) 6480464 Cisplatin results in decreased expression of PPARGC1A mRNA and Cisplatin results in decreased expression of PPARGC1A protein CTD PMID:32567747 more ... cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of PPARGC1A mRNA CTD PMID:33661552 and PMID:36006825 cisplatin multiple interactions EXP 6480464 6-chloro-2 more ... CTD PMID:33661552 clenbuterol increases expression ISO Ppargc1a (Mus musculus) 6480464 Clenbuterol results in increased expression of PPARGC1A mRNA CTD PMID:17446185 clenbuterol increases expression EXP 6480464 Clenbuterol results in increased expression of PPARGC1A mRNA CTD PMID:17446185 clenbuterol multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Propranolol inhibits the reaction [Clenbuterol results in increased expression of PPARGC1A mRNA] CTD PMID:17446185 clofibrate increases expression ISO PPARGC1A (Homo sapiens) 6480464 Clofibrate results in increased expression of PPARGC1A mRNA CTD PMID:27089845 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of PPARGC1A protein CTD PMID:22982409 colforsin daropate hydrochloride increases expression ISO PPARGC1A (Homo sapiens) 6480464 Colforsin results in increased expression of PPARGC1A mRNA CTD PMID:16357189 copper atom decreases expression EXP 6480464 Copper results in decreased expression of PPARGC1A mRNA CTD PMID:22465980 copper atom multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in decreased expression of PPARGC1A mRNA CTD PMID:31162603 copper atom increases expression EXP 6480464 Copper deficiency results in increased expression of PPARGC1A mRNA and Copper deficiency results in increased expression of PPARGC1A protein CTD PMID:18993053 copper(0) decreases expression EXP 6480464 Copper results in decreased expression of PPARGC1A mRNA CTD PMID:22465980 copper(0) multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in decreased expression of PPARGC1A mRNA CTD PMID:31162603 copper(0) increases expression EXP 6480464 Copper deficiency results in increased expression of PPARGC1A mRNA and Copper deficiency results in increased expression of PPARGC1A protein CTD PMID:18993053 copper(II) sulfate decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of PPARGC1A mRNA CTD PMID:19549813 cortisol multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of PPARGC1A mRNA and Rosmarinic Acid affects the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of PPARGC1A mRNA] CTD PMID:33476690 cortisone increases expression ISO PPARGC1A (Homo sapiens) 6480464 Cortisone results in increased expression of PPARGC1A mRNA CTD PMID:23056435 creatine increases expression ISO PPARGC1A (Homo sapiens) 6480464 Creatine results in increased expression of PPARGC1A mRNA CTD PMID:23056435 crocidolite asbestos affects expression ISO PPARGC1A (Homo sapiens) 6480464 Asbestos and Crocidolite affects the expression of PPARGC1A mRNA CTD PMID:17331233 crocidolite asbestos decreases expression ISO Ppargc1a (Mus musculus) 6480464 Asbestos and Crocidolite results in decreased expression of PPARGC1A mRNA CTD PMID:29279043 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [[Lipopolysaccharides co-treated with Tobacco Smoke Pollution] results in decreased expression of PPARGC1A mRNA] more ... CTD PMID:28951138 and PMID:32980475 curcumin increases expression EXP 6480464 Curcumin results in increased expression of PPARGC1A protein CTD PMID:32980475 cyclosporin A decreases expression ISO Ppargc1a (Mus musculus) 6480464 Cyclosporine results in decreased expression of PPARGC1A mRNA CTD PMID:19770486 cyclosporin A decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Cyclosporine results in decreased expression of PPARGC1A mRNA CTD PMID:20106945 more ... cyclosporin A multiple interactions EXP 6480464 Cyclosporine inhibits the reaction [Ionomycin results in increased expression of PPARGC1A mRNA] CTD PMID:17516843 cyproconazole increases expression EXP 6480464 cyproconazole results in increased expression of PPARGC1A mRNA CTD PMID:29038839 cyproconazole multiple interactions EXP 6480464 [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of PPARGC1A mRNA and [cyproconazole co-treated with epoxiconazole] results in increased expression of PPARGC1A mRNA CTD PMID:29038839 D-glucose increases acetylation ISO PPARGC1A (Homo sapiens) 6480464 Glucose results in increased acetylation of PPARGC1A protein CTD PMID:19071085 D-glucose multiple interactions EXP 6480464 Inositol inhibits the reaction [Glucose results in decreased expression of PPARGC1A protein] and SRT1720 inhibits the reaction [Glucose results in decreased expression of PPARGC1A protein] CTD PMID:31639451 and PMID:35243728 D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of PPARGC1A protein CTD PMID:31639451 and PMID:35243728 D-glucose increases expression ISO PPARGC1A (Homo sapiens) 6480464 Glucose deficiency results in increased expression of PPARGC1A mRNA and Glucose results in increased expression of PPARGC1A mRNA CTD PMID:26811028 and PMID:33962019 D-glucose affects expression EXP 6480464 Glucose affects the expression of PPARGC1A mRNA CTD PMID:24349266 D-glucose decreases expression ISO Ppargc1a (Mus musculus) 6480464 Glucose results in decreased expression of PPARGC1A mRNA and Glucose results in decreased expression of PPARGC1A protein CTD PMID:23090186 more ... D-glucose multiple interactions ISO Ppargc1a (Mus musculus) 6480464 4-phenylbutyric acid inhibits the reaction [Glucose results in decreased expression of PPARGC1A mRNA] more ... CTD PMID:23090186 more ... D-glucose decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Glucose deficiency results in decreased expression of PPARGC1A mRNA more ... CTD PMID:17855661 more ... D-glucose multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 6-chloro-2 more ... CTD PMID:17855661 more ... D-glucurono-6,3-lactone increases expression ISO PPARGC1A (Homo sapiens) 6480464 glucuronolactone results in increased expression of PPARGC1A mRNA CTD PMID:23056435 dapagliflozin multiple interactions EXP 6480464 [Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of PPARGC1A protein] and dapagliflozin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of PPARGC1A protein] CTD PMID:32259528 DDE increases activity ISO PPARGC1A (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene results in increased activity of PPARGC1A protein CTD PMID:27589886 DDT multiple interactions ISO Ppargc1a (Mus musculus) 6480464 DDT promotes the reaction [PPARGC1A protein binds to CYP2B10 promoter] CTD PMID:23684557 decanoic acid increases expression ISO PPARGC1A (Homo sapiens) 6480464 decanoic acid results in increased expression of PPARGC1A mRNA CTD PMID:23056435 dehydroepiandrosterone increases expression EXP 6480464 Dehydroepiandrosterone results in increased expression of PPARGC1A mRNA CTD PMID:12659879 dehydroepiandrosterone increases expression EXP 155226858 dehydroepiandrosterone increases expression of Ppargc1a protein in heart RGD Delta(9)-tetrahydrocannabinolic acid increases expression ISO Ppargc1a (Mus musculus) 6480464 delta(9)-tetrahydrocannabinolic acid results in increased expression of PPARGC1A mRNA CTD PMID:28853159 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of PPARGC1A protein CTD PMID:21094144 dexamethasone multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [BMP7 protein co-treated with INS1 protein co-treated with Triiodothyronine co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with Indomethacin co-treated with Nicotine] affects the expression of PPARGC1A mRNA more ... CTD PMID:29288687 more ... dexamethasone multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with Rosiglitazone co-treated with 4 more ... CTD PMID:28628672 more ... dexamethasone increases expression ISO PPARGC1A (Homo sapiens) 6480464 Dexamethasone results in increased expression of PPARGC1A mRNA CTD PMID:19022236 more ... dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of PPARGC1A mRNA CTD PMID:18972406 dexamethasone multiple interactions EXP 6480464 [Dexamethasone co-treated with Cyclic AMP] results in increased expression of PPARGC1A mRNA more ... CTD PMID:18972406 more ... dextran sulfate multiple interactions EXP 6480464 Hesperidin inhibits the reaction [Dextran Sulfate results in decreased expression of PPARGC1A protein] CTD PMID:30811821 dextran sulfate decreases expression EXP 6480464 Dextran Sulfate results in decreased expression of PPARGC1A protein CTD PMID:30811821 Di-n-hexyl phthalate decreases expression EXP 6480464 di-n-hexyl phthalate results in decreased expression of PPARGC1A protein CTD PMID:32693021 Di-n-octyl phthalate decreases expression ISO PPARGC1A (Homo sapiens) 6480464 di-n-octyl phthalate results in decreased expression of PPARGC1A mRNA and di-n-octyl phthalate results in decreased expression of PPARGC1A protein CTD PMID:34822940 diarsenic trioxide increases expression ISO PPARGC1A (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of PPARGC1A mRNA CTD PMID:20458559 diarsenic trioxide increases expression ISO Ppargc1a (Mus musculus) 6480464 Arsenic Trioxide results in increased expression of PPARGC1A mRNA CTD PMID:30362509 diarsenic trioxide multiple interactions EXP 6480464 salvianolic acid A inhibits the reaction [Arsenic Trioxide results in decreased expression of PPARGC1A protein] CTD PMID:29867492 diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of PPARGC1A protein CTD PMID:29867492 diarsenic trioxide multiple interactions ISO Ppargc1a (Mus musculus) 6480464 salvianolic acid A inhibits the reaction [Arsenic Trioxide results in decreased expression of PPARGC1A protein] and Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of PPARGC1A mRNA] CTD PMID:29867492 and PMID:30362509 diarsenic trioxide decreases expression ISO Ppargc1a (Mus musculus) 6480464 Arsenic Trioxide results in decreased expression of PPARGC1A protein CTD PMID:29867492 dibutyl phthalate increases expression ISO Ppargc1a (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of PPARGC1A mRNA CTD PMID:17361019 and PMID:21266533 dibutyl phthalate multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in decreased expression of PPARGC1A mRNA CTD PMID:37021957 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of PPARGC1A protein CTD PMID:32525071 dibutyl phthalate multiple interactions EXP 6480464 taxifolin inhibits the reaction [Dibutyl Phthalate results in decreased expression of PPARGC1A protein] CTD PMID:32525071 dichloroacetic acid decreases expression ISO Ppargc1a (Mus musculus) 6480464 Dichloroacetic Acid results in decreased expression of PPARGC1A mRNA CTD PMID:28962523 dichloromethane decreases expression ISO Ppargc1a (Mus musculus) 6480464 Methylene Chloride results in decreased expression of PPARGC1A mRNA CTD PMID:28392392 diclofenac increases expression ISO Ppargc1a (Mus musculus) 6480464 Diclofenac results in increased expression of PPARGC1A mRNA CTD PMID:26934552 diclofenac affects expression ISO PPARGC1A (Homo sapiens) 6480464 Diclofenac affects the expression of PPARGC1A mRNA CTD PMID:24752500 diethyl phthalate multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in decreased expression of PPARGC1A mRNA CTD PMID:37021957 diethylstilbestrol multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 Diethylstilbestrol promotes the reaction [ESR1 protein binds to PPARGC1A protein] CTD PMID:32088792 dihydrofolic acid increases expression ISO PPARGC1A (Homo sapiens) 6480464 dihydrofolate results in increased expression of PPARGC1A mRNA CTD PMID:23056435 diisobutyl phthalate multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in decreased expression of PPARGC1A mRNA CTD PMID:37021957 diisononyl phthalate multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in decreased expression of PPARGC1A mRNA CTD PMID:37021957 dioxygen decreases expression ISO Ppargc1a (Mus musculus) 6480464 Oxygen deficiency results in decreased expression of PPARGC1A mRNA and Oxygen deficiency results in decreased expression of PPARGC1A protein CTD PMID:21113404 dioxygen multiple interactions EXP 6480464 [Nitrites co-treated with Oxygen deficiency] results in increased expression of and results in decreased acetylation of PPARGC1A protein more ... CTD PMID:22892143 more ... dioxygen increases expression ISO Ppargc1a (Mus musculus) 6480464 Oxygen deficiency results in increased expression of PPARGC1A mRNA CTD PMID:23539316 dioxygen multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 EPAS1 gene mutant form inhibits the reaction [Oxygen deficiency results in decreased expression of PPARGC1A protein] and HIF1A gene mutant form inhibits the reaction [Oxygen deficiency results in decreased expression of PPARGC1A protein] CTD PMID:24503013 dioxygen decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Oxygen deficiency results in decreased expression of PPARGC1A protein CTD PMID:24503013 dioxygen multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of PPARGC1A protein more ... CTD PMID:21113404 and PMID:28477916 disodium selenite multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PPARGC1A mRNA] CTD PMID:26522834 dodecanoic acid increases expression ISO PPARGC1A (Homo sapiens) 6480464 lauric acid results in increased expression of PPARGC1A mRNA CTD PMID:23056435 dorsomorphin multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:22062806 more ... dorsomorphin increases expression EXP 6480464 dorsomorphin results in increased expression of PPARGC1A protein CTD PMID:19853624 dorsomorphin multiple interactions EXP 6480464 dorsomorphin inhibits the reaction [25-hydroxyprotopanaxadiol results in increased phosphorylation of PPARGC1A protein] more ... CTD PMID:19853624 more ... dorsomorphin multiple interactions ISO Ppargc1a (Mus musculus) 6480464 dorsomorphin inhibits the reaction [Metformin results in increased expression of PPARGC1A mRNA] and dorsomorphin promotes the reaction [AICA ribonucleotide results in decreased expression of PPARGC1A mRNA] CTD PMID:24428821 doxorubicin decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Doxorubicin results in decreased expression of PPARGC1A mRNA and Doxorubicin results in decreased expression of PPARGC1A protein CTD PMID:26781513 more ... doxorubicin multiple interactions EXP 6480464 Melatonin inhibits the reaction [Doxorubicin results in decreased expression of PPARGC1A protein] more ... CTD PMID:29966675 and PMID:30831132 doxorubicin increases expression ISO Ppargc1a (Mus musculus) 6480464 Doxorubicin results in increased expression of PPARGC1A mRNA CTD PMID:28710503 doxorubicin multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Lovastatin inhibits the reaction [Doxorubicin results in increased expression of PPARGC1A mRNA] and NSC 23766 inhibits the reaction [Doxorubicin results in increased expression of PPARGC1A mRNA] CTD PMID:28710503 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of PPARGC1A mRNA and Doxorubicin results in decreased expression of PPARGC1A protein CTD PMID:26678157 more ... doxorubicin affects response to substance ISO PPARGC1A (Homo sapiens) 6480464 PPARGC1A affects the susceptibility to Doxorubicin CTD PMID:26781513 doxorubicin multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 3-(2 more ... CTD PMID:26781513 more ... doxorubicin increases expression ISO PPARGC1A (Homo sapiens) 6480464 Doxorubicin results in increased expression of PPARGC1A protein CTD PMID:26781513 edaravone multiple interactions EXP 6480464 Edaravone inhibits the reaction [Rotenone results in decreased expression of PPARGC1A mRNA] CTD PMID:30240821 elemental selenium decreases expression ISO Ppargc1a (Mus musculus) 6480464 Selenium results in decreased expression of PPARGC1A mRNA CTD PMID:28810182 ellagic acid multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of PPARGC1A mRNA] CTD PMID:30503583 ellagic acid decreases expression ISO Ppargc1a (Mus musculus) 6480464 Ellagic Acid results in decreased expression of PPARGC1A mRNA CTD PMID:30503583 enalapril increases expression EXP 6480464 Enalapril results in increased expression of PPARGC1A mRNA CTD PMID:18765277 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of PPARGC1A mRNA CTD PMID:29391264 enilconazole decreases expression ISO PPARGC1A (Homo sapiens) 6480464 enilconazole results in decreased expression of PPARGC1A mRNA CTD PMID:32201337 epoxiconazole multiple interactions EXP 6480464 [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of PPARGC1A mRNA and [cyproconazole co-treated with epoxiconazole] results in increased expression of PPARGC1A mRNA CTD PMID:29038839 epoxiconazole increases expression ISO Ppargc1a (Mus musculus) 6480464 epoxiconazole results in increased expression of PPARGC1A mRNA CTD PMID:35436446 epoxiconazole increases expression EXP 6480464 epoxiconazole results in increased expression of PPARGC1A mRNA CTD PMID:29038839 Erythropoietin multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of and results in increased acetylation of PPARGC1A protein] and SIRT1 protein affects the reaction [Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of PPARGC1A protein]] CTD PMID:28456571 ethanol increases acetylation ISO Ppargc1a (Mus musculus) 6480464 Ethanol results in increased acetylation of PPARGC1A protein CTD PMID:20007851 ethanol affects splicing ISO Ppargc1a (Mus musculus) 6480464 Ethanol affects the splicing of PPARGC1A mRNA CTD PMID:30319688 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of PPARGC1A protein CTD PMID:30368987 ethanol affects localization ISO Ppargc1a (Mus musculus) 6480464 Ethanol affects the localization of PPARGC1A protein CTD PMID:27765815 ethanol increases expression EXP 6480464 Ethanol results in increased expression of PPARGC1A mRNA CTD PMID:16098508 and PMID:18793633 ethanol decreases expression ISO Ppargc1a (Mus musculus) 6480464 Ethanol results in decreased expression of PPARGC1A mRNA and Ethanol results in decreased expression of PPARGC1A protein CTD PMID:18755807 more ... ethanol multiple interactions EXP 6480464 Hesperidin inhibits the reaction [Ethanol results in decreased expression of PPARGC1A protein] more ... CTD PMID:18793633 more ... ethanol increases acetylation EXP 6480464 Ethanol results in increased acetylation of PPARGC1A protein CTD PMID:24769256 ethanol decreases acetylation ISO Ppargc1a (Mus musculus) 6480464 Ethanol results in decreased acetylation of PPARGC1A protein CTD PMID:24892905 ethanol multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Ethanol results in decreased activity of SIRT1 protein] which results in increased acetylation of PPARGC1A protein more ... CTD PMID:18755807 more ... etoposide increases expression ISO PPARGC1A (Homo sapiens) 6480464 Etoposide results in increased expression of PPARGC1A mRNA CTD PMID:26259609 etoposide multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 Etoposide promotes the reaction [PPARGC1A protein results in increased activity of ESRRA protein] CTD PMID:30818834 farnesol multiple interactions EXP 6480464 Farnesol inhibits the reaction [Atorvastatin inhibits the reaction [TNF protein results in decreased expression of PPARGC1A protein]] CTD PMID:22343369 fenofibrate multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of PPARGC1A protein] CTD PMID:32730863 fenofibrate multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of PPARGC1A mRNA] CTD PMID:28871336 fenoterol increases expression ISO Ppargc1a (Mus musculus) 6480464 Fenoterol results in increased expression of PPARGC1A mRNA CTD PMID:34601065 fenpyroximate multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 fenpyroximate inhibits the reaction [PPARGC1A protein results in increased activity of ESRRA protein] CTD PMID:30818834 ferulic acid multiple interactions EXP 6480464 ferulic acid inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A protein] CTD PMID:31029786 ferulic acid decreases expression ISO Ppargc1a (Mus musculus) 6480464 ferulic acid results in decreased expression of PPARGC1A mRNA CTD PMID:30503583 ferulic acid multiple interactions ISO Ppargc1a (Mus musculus) 6480464 ferulic acid inhibits the reaction [sodium arsenate results in increased expression of PPARGC1A mRNA] CTD PMID:30503583 flavonoids increases expression ISO PPARGC1A (Homo sapiens) 6480464 Flavonoids results in increased expression of PPARGC1A protein CTD PMID:23063593 flavonoids multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Flavonoids results in increased expression of PPARGC1A protein] CTD PMID:23063593 fluoxastrobin multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 fluoxastrobin inhibits the reaction [PPARGC1A protein results in increased activity of ESRRA protein] CTD PMID:30818834 folic acid decreases expression ISO Ppargc1a (Mus musculus) 6480464 Folic Acid results in decreased expression of PPARGC1A more ... CTD PMID:24275386 more ... folic acid multiple interactions ISO Ppargc1a (Mus musculus) 6480464 6 more ... CTD PMID:31447676 folpet decreases expression ISO Ppargc1a (Mus musculus) 6480464 folpet results in decreased expression of PPARGC1A mRNA CTD PMID:31558096 FR900359 increases phosphorylation ISO PPARGC1A (Homo sapiens) 6480464 FR900359 results in increased phosphorylation of PPARGC1A protein CTD PMID:37730182 fructose decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Fructose results in decreased expression of PPARGC1A mRNA CTD PMID:18063403 fructose decreases expression EXP 6480464 Fructose results in decreased expression of PPARGC1A mRNA CTD PMID:23968387 fructose multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [Fructose co-treated with Palmitic Acid] results in decreased expression of PPARGC1A protein and Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of PPARGC1A protein] CTD PMID:32730863 fructose increases expression EXP 6480464 Fructose results in increased expression of PPARGC1A mRNA and Fructose results in increased expression of PPARGC1A protein CTD PMID:19196556 and PMID:21212096 fructose multiple interactions EXP 6480464 [Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of PPARGC1A protein] more ... CTD PMID:19196556 more ... fulvestrant multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] affects the methylation of PPARGC1A gene more ... CTD PMID:18511507 and PMID:31601247 fulvestrant multiple interactions EXP 6480464 fulvestrant inhibits the reaction [FSHB protein promotes the reaction [ESR1 protein binds to PPARGC1A protein]] CTD PMID:18511507 galactose decreases expression EXP 6480464 Galactose results in decreased expression of PPARGC1A protein CTD PMID:28302704 gamma-hexachlorocyclohexane increases expression ISO PPARGC1A (Homo sapiens) 6480464 Hexachlorocyclohexane results in increased expression of PPARGC1A mRNA CTD PMID:23777605 Genipin multiple interactions ISO Ppargc1a (Mus musculus) 6480464 genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of PPARGC1A protein] and sirtinol inhibits the reaction [genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of PPARGC1A protein]] CTD PMID:28477916 Geniposide decreases expression ISO Ppargc1a (Mus musculus) 6480464 geniposide results in decreased expression of PPARGC1A mRNA CTD PMID:34718029 Gingerenone A increases expression ISO Ppargc1a (Mus musculus) 6480464 gingerenone A results in increased expression of PPARGC1A mRNA and gingerenone A results in increased expression of PPARGC1A protein CTD PMID:28556482 ginsenoside Rg2 decreases expression ISO PPARGC1A (Homo sapiens) 6480464 ginsenoside Rg2 results in decreased expression of PPARGC1A mRNA CTD PMID:22062806 ginsenoside Rg2 multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 dorsomorphin inhibits the reaction [ginsenoside Rg2 results in decreased expression of PPARGC1A mRNA] CTD PMID:22062806 glucagon multiple interactions EXP 6480464 [Glucagon co-treated with Cyclic AMP] results in increased expression of PPARGC1A mRNA more ... CTD PMID:22676303 glucose increases acetylation ISO PPARGC1A (Homo sapiens) 6480464 Glucose results in increased acetylation of PPARGC1A protein CTD PMID:19071085 glucose multiple interactions EXP 6480464 Inositol inhibits the reaction [Glucose results in decreased expression of PPARGC1A protein] and SRT1720 inhibits the reaction [Glucose results in decreased expression of PPARGC1A protein] CTD PMID:31639451 and PMID:35243728 glucose increases expression ISO PPARGC1A (Homo sapiens) 6480464 Glucose deficiency results in increased expression of PPARGC1A mRNA and Glucose results in increased expression of PPARGC1A mRNA CTD PMID:26811028 and PMID:33962019 glucose decreases expression EXP 6480464 Glucose results in decreased expression of PPARGC1A protein CTD PMID:31639451 and PMID:35243728 glucose affects expression EXP 6480464 Glucose affects the expression of PPARGC1A mRNA CTD PMID:24349266 glucose decreases expression ISO Ppargc1a (Mus musculus) 6480464 Glucose results in decreased expression of PPARGC1A mRNA and Glucose results in decreased expression of PPARGC1A protein CTD PMID:23090186 more ... glucose multiple interactions ISO Ppargc1a (Mus musculus) 6480464 4-phenylbutyric acid inhibits the reaction [Glucose results in decreased expression of PPARGC1A mRNA] more ... CTD PMID:23090186 more ... glucose decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Glucose deficiency results in decreased expression of PPARGC1A mRNA more ... CTD PMID:17855661 more ... glucose multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 6-chloro-2 more ... CTD PMID:17855661 more ... glutathione increases expression ISO PPARGC1A (Homo sapiens) 6480464 Glutathione analog results in increased expression of PPARGC1A mRNA CTD PMID:23056435 GW 1929 multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 GW 1929 promotes the reaction [PPARGC1A protein binds to PPARG protein] CTD PMID:32407875 GW 501516 multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [GW 501516 co-treated with PPARD protein] results in increased expression of PPARGC1A mRNA CTD PMID:17275789 GW 501516 increases expression ISO Ppargc1a (Mus musculus) 6480464 GW 501516 results in increased expression of PPARGC1A mRNA CTD PMID:17275789 GW 501516 increases expression ISO PPARGC1A (Homo sapiens) 6480464 GW 501516 results in increased expression of PPARGC1A mRNA CTD PMID:23056435 haloperidol multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Cannabidiol co-treated with Haloperidol] results in increased expression of PPARGC1A protein CTD PMID:30217539 harmine increases expression ISO Ppargc1a (Mus musculus) 6480464 Harmine results in increased expression of PPARGC1A protein CTD PMID:27805061 harmine multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Harmine affects the reaction [Dietary Fats affects the expression of PPARGC1A mRNA] CTD PMID:27805061 hemin multiple interactions EXP 6480464 Hemin inhibits the reaction [manganese chloride affects the expression of PPARGC1A protein] CTD PMID:30040983 herbicide multiple interactions ISO Ppargc1a (Mus musculus) 6480464 arginyl-2 and '6'-dimethyltyrosyl-lysyl-phenylalaninamide promotes the reaction [Herbicides results in increased expression of PPARGC1A mRNA] CTD PMID:21318024 herbicide increases expression ISO Ppargc1a (Mus musculus) 6480464 Herbicides results in increased expression of PPARGC1A mRNA CTD PMID:21318024 hesperidin multiple interactions EXP 6480464 Hesperidin inhibits the reaction [Dextran Sulfate results in decreased expression of PPARGC1A protein] and Hesperidin inhibits the reaction [Ethanol results in decreased expression of PPARGC1A protein] CTD PMID:30368987 and PMID:30811821 hexadecanoic acid increases expression ISO PPARGC1A (Homo sapiens) 6480464 Palmitic Acid results in increased expression of PPARGC1A mRNA CTD PMID:23056435 hexadecanoic acid decreases expression ISO Ppargc1a (Mus musculus) 6480464 Palmitic Acid results in decreased expression of PPARGC1A mRNA and Palmitic Acid results in decreased expression of PPARGC1A protein CTD PMID:34485530 hexadecanoic acid multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARGC1A mRNA more ... CTD PMID:26847930 and PMID:34485530 hexadecanoic acid multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [Fructose co-treated with Palmitic Acid] results in decreased expression of PPARGC1A protein and Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of PPARGC1A protein] CTD PMID:32730863 hexadecanoic acid increases expression EXP 6480464 Palmitic Acid results in increased expression of PPARGC1A mRNA CTD PMID:23056435 Honokiol multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Pyruvaldehyde co-treated with honokiol] results in increased expression of PPARGC1A protein CTD PMID:26723916 hydrogen cyanide increases expression ISO Ppargc1a (Mus musculus) 6480464 Hydrogen Cyanide results in increased expression of PPARGC1A mRNA CTD PMID:33914522 hydrogen peroxide multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Hydrogen Peroxide co-treated with Staurosporine] results in increased acetylation of PPARGC1A protein and resveratrol inhibits the reaction [[Hydrogen Peroxide co-treated with Staurosporine] results in increased acetylation of PPARGC1A protein] CTD PMID:23293585 hydrogen peroxide multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of PPARGC1A protein] and trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of PPARGC1A protein] CTD PMID:30104959 hydrogen peroxide decreases expression EXP 6480464 Hydrogen Peroxide results in decreased expression of PPARGC1A mRNA and Hydrogen Peroxide results in decreased expression of PPARGC1A protein CTD PMID:24349266 and PMID:30104959 icariin increases expression ISO Ppargc1a (Mus musculus) 6480464 icariin results in increased expression of PPARGC1A mRNA and icariin results in increased expression of PPARGC1A protein CTD PMID:17883938 icariin multiple interactions EXP 6480464 Histone Deacetylase Inhibitors inhibits the reaction [icariin inhibits the reaction [Rotenone results in decreased expression of PPARGC1A protein]] and icariin inhibits the reaction [Rotenone results in decreased expression of PPARGC1A protein] CTD PMID:31251943 ICI 118551 decreases expression ISO Ppargc1a (Mus musculus) 6480464 ICI 118551 results in decreased expression of PPARGC1A mRNA CTD PMID:17446185 Ile(5)-angiotensin II decreases expression EXP 6480464 Angiotensin II results in decreased expression of PPARGC1A protein CTD PMID:37269933 Ile(5)-angiotensin II multiple interactions EXP 6480464 celastrol methyl ester inhibits the reaction [Angiotensin II results in decreased expression of PPARGC1A protein] CTD PMID:37269933 imidacloprid decreases expression ISO Ppargc1a (Mus musculus) 6480464 imidacloprid results in decreased expression of PPARGC1A protein CTD PMID:27960282 indole-3-methanol affects expression EXP 6480464 indole-3-carbinol affects the expression of PPARGC1A mRNA CTD PMID:21396975 indometacin multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [BMP7 protein co-treated with INS1 protein co-treated with Triiodothyronine co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with Indomethacin co-treated with Nicotine] affects the expression of PPARGC1A mRNA and [BMP7 protein co-treated with INS1 protein co-treated with Triiodothyronine co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with Indomethacin co-treated with Nicotine] affects the expression of PPARGC1A protein CTD PMID:33091441 indometacin multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of PPARGC1A mRNA CTD PMID:28628672 inositol multiple interactions EXP 6480464 Inositol inhibits the reaction [Glucose results in decreased expression of PPARGC1A protein] CTD PMID:35243728 inulin multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of PPARGC1A mRNA CTD PMID:36331819 ionomycin multiple interactions EXP 6480464 Cyclosporine inhibits the reaction [Ionomycin results in increased expression of PPARGC1A mRNA] and KN 62 affects the reaction [Ionomycin results in increased expression of PPARGC1A mRNA] CTD PMID:17516843 ionomycin increases expression EXP 6480464 Ionomycin results in increased expression of PPARGC1A mRNA CTD PMID:17516843 iprodione decreases expression EXP 6480464 iprodione results in decreased expression of PPARGC1A mRNA CTD PMID:33586219 and PMID:34060014 iprodione multiple interactions EXP 6480464 Chlorpyrifos promotes the reaction [iprodione results in decreased expression of PPARGC1A mRNA] and iprodione promotes the reaction [Chlorpyrifos results in decreased expression of PPARGC1A mRNA] CTD PMID:33586219 and PMID:34060014 isobutanol multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of PPARGC1A mRNA CTD PMID:29432896 isoniazide multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 acadesine inhibits the reaction [Isoniazid results in decreased expression of PPARGC1A protein] CTD PMID:28556920 isoniazide decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Isoniazid results in decreased expression of PPARGC1A protein CTD PMID:28556920 isoprenaline increases expression EXP 6480464 Isoproterenol results in increased expression of PPARGC1A mRNA CTD PMID:19808358 isoprenaline increases expression ISO Ppargc1a (Mus musculus) 6480464 Isoproterenol results in increased expression of PPARGC1A mRNA CTD PMID:34601065 isoprenaline decreases expression EXP 6480464 Isoproterenol results in decreased expression of PPARGC1A mRNA and Isoproterenol results in decreased expression of PPARGC1A protein CTD PMID:25045214 isoprenaline multiple interactions EXP 6480464 Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARGC1A mRNA] more ... CTD PMID:25045214 isoxazoles increases expression ISO PPARGC1A (Homo sapiens) 6480464 Isoxazoles results in increased expression of PPARGC1A mRNA CTD PMID:24290359 kaempferol increases expression ISO PPARGC1A (Homo sapiens) 6480464 kaempferol results in increased expression of PPARGC1A mRNA CTD PMID:17327447 ketoconazole decreases expression EXP 6480464 Ketoconazole results in decreased expression of PPARGC1A mRNA CTD PMID:37077353 ketotifen increases expression ISO PPARGC1A (Homo sapiens) 6480464 Ketotifen results in increased expression of PPARGC1A mRNA CTD PMID:27089845 kresoxim-methyl multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 kresoxim-methyl inhibits the reaction [PPARGC1A protein results in increased activity of ESRRA protein] CTD PMID:30818834 L-1,4-dithiothreitol increases expression ISO PPARGC1A (Homo sapiens) 6480464 Dithiothreitol results in increased expression of PPARGC1A mRNA CTD PMID:23056435 L-ascorbic acid increases expression ISO PPARGC1A (Homo sapiens) 6480464 Ascorbic Acid results in increased expression of PPARGC1A mRNA CTD PMID:23056435 L-glutamic acid multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [Glutamic Acid co-treated with asiatic acid] results in increased expression of PPARGC1A protein CTD PMID:22447225 L-methionine increases expression EXP 6480464 Methionine deficiency results in increased expression of PPARGC1A protein CTD PMID:17716000 lead diacetate multiple interactions ISO Ppargc1a (Mus musculus) 6480464 PPARGC1A protein affects the reaction [lead acetate results in increased expression of SIRT3 protein] more ... CTD PMID:27236077 lead diacetate increases expression ISO Ppargc1a (Mus musculus) 6480464 lead acetate results in increased expression of PPARGC1A protein CTD PMID:27236077 leflunomide increases expression ISO PPARGC1A (Homo sapiens) 6480464 leflunomide results in increased expression of PPARGC1A mRNA CTD PMID:28988120 and PMID:29427785 Licarin A multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of PPARGC1A mRNA more ... CTD PMID:29288687 limonene multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [limonene co-treated with Pyruvaldehyde] results in increased expression of PPARGC1A protein CTD PMID:28986142 linagliptin multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Linagliptin inhibits the reaction [Cisplatin results in decreased expression of PPARGC1A protein] CTD PMID:32567747 linagliptin multiple interactions EXP 6480464 Linagliptin inhibits the reaction [Acetic Acid results in decreased expression of PPARGC1A mRNA] CTD PMID:35122774 linoleic acid increases expression EXP 6480464 Linoleic Acid results in increased expression of PPARGC1A mRNA CTD PMID:23056435 linoleic acid increases expression ISO PPARGC1A (Homo sapiens) 6480464 Linoleic Acid results in increased expression of PPARGC1A mRNA CTD PMID:23056435 lipoic acid multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [Acetylcarnitine co-treated with Thioctic Acid] results in increased expression of PPARGC1A protein CTD PMID:20414966 lipoic acid decreases expression ISO Ppargc1a (Mus musculus) 6480464 Thioctic Acid results in decreased expression of PPARGC1A protein CTD PMID:37739047 lipoic acid multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Thioctic Acid co-treated with Silicon] results in increased expression of PPARGC1A protein and Thioctic Acid inhibits the reaction [Sodium Fluoride results in decreased expression of PPARGC1A mRNA] CTD PMID:34252510 and PMID:37739047 lipoic acid multiple interactions EXP 6480464 Thioctic Acid inhibits the reaction [Dietary Fats results in decreased expression of PPARGC1A mRNA] CTD PMID:22464149 lipoic acid increases expression ISO PPARGC1A (Homo sapiens) 6480464 Thioctic Acid results in increased expression of PPARGC1A protein CTD PMID:20414966 lipopolysaccharide multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Ethylene Chlorohydrin co-treated with Lipopolysaccharides] results in increased expression of PPARGC1A mRNA more ... CTD PMID:21873422 and PMID:31499194 lipopolysaccharide multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 S-(1 and 2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in decreased expression of PPARGC1A mRNA] CTD PMID:35811015 lipopolysaccharide decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Lipopolysaccharides results in decreased expression of PPARGC1A mRNA CTD PMID:35811015 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of PPARGC1A protein CTD PMID:19853624 lipopolysaccharide decreases expression EXP 6480464 Lipopolysaccharides results in decreased expression of PPARGC1A protein CTD PMID:22610192 lipopolysaccharide multiple interactions EXP 6480464 [Aminoimidazole Carboxamide analog co-treated with Lipopolysaccharides] results in increased expression of PPARGC1A protein more ... CTD PMID:19853624 more ... lipopolysaccharide decreases expression ISO Ppargc1a (Mus musculus) 6480464 Lipopolysaccharides results in decreased expression of PPARGC1A mRNA CTD PMID:16847310 more ... liraglutide multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Liraglutide inhibits the reaction [IL1B protein results in decreased expression of PPARGC1A protein] CTD PMID:32898504 loliolide decreases expression ISO Ppargc1a (Mus musculus) 6480464 loliolide results in decreased expression of PPARGC1A protein CTD PMID:33567534 losartan multiple interactions EXP 6480464 Losartan inhibits the reaction [AGT protein results in increased expression of PPARGC1A mRNA] CTD PMID:19109942 losartan increases expression EXP 6480464 Losartan results in increased expression of PPARGC1A mRNA CTD PMID:18765277 and PMID:18971572 lovastatin multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Lovastatin inhibits the reaction [Doxorubicin results in increased expression of PPARGC1A mRNA] CTD PMID:28710503 luzindole multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 luzindole inhibits the reaction [Melatonin inhibits the reaction [Cadmium Chloride results in increased acetylation of PPARGC1A protein]] and luzindole inhibits the reaction [Melatonin inhibits the reaction [Cadmium results in increased acetylation of PPARGC1A protein]] CTD PMID:25159133 LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Calcitriol results in increased expression of PPARGC1A protein] more ... CTD PMID:17179207 and PMID:30194976 LY294002 multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltiprotoporphyrin results in increased expression of PPARGC1A mRNA] and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [tricarbonylchloro(glycinato)ruthenium(II) results in increased expression of PPARGC1A mRNA] CTD PMID:24041027 mabuterol increases expression ISO Ppargc1a (Mus musculus) 6480464 mabuterol results in increased expression of PPARGC1A mRNA CTD PMID:34601065 Magnolol multiple interactions EXP 6480464 [magnolol co-treated with Pyruvaldehyde] results in increased expression of PPARGC1A protein CTD PMID:28919305 malic acid increases expression ISO PPARGC1A (Homo sapiens) 6480464 malic acid results in increased expression of PPARGC1A mRNA CTD PMID:23056435 malonic acid increases expression ISO PPARGC1A (Homo sapiens) 6480464 malonic acid results in increased expression of PPARGC1A mRNA CTD PMID:23056435 manganese atom increases expression EXP 6480464 Manganese results in increased expression of PPARGC1A protein CTD PMID:24787138 manganese atom multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [manganese chloride results in increased abundance of Manganese] affects the reaction [STAT3 protein binds to PPARGC1A protein] CTD PMID:34018660 manganese(0) increases expression EXP 6480464 Manganese results in increased expression of PPARGC1A protein CTD PMID:24787138 manganese(0) multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [manganese chloride results in increased abundance of Manganese] affects the reaction [STAT3 protein binds to PPARGC1A protein] CTD PMID:34018660 manganese(II) chloride affects expression EXP 6480464 manganese chloride affects the expression of PPARGC1A protein CTD PMID:30040983 manganese(II) chloride increases acetylation ISO Ppargc1a (Mus musculus) 6480464 manganese chloride results in increased acetylation of PPARGC1A protein CTD PMID:34738708 manganese(II) chloride multiple interactions ISO Ppargc1a (Mus musculus) 6480464 6-chloro-2 more ... CTD PMID:34018660 and PMID:34738708 manganese(II) chloride multiple interactions EXP 6480464 Hemin inhibits the reaction [manganese chloride affects the expression of PPARGC1A protein] CTD PMID:30040983 mangiferin multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [mangiferin co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARGC1A mRNA and [mangiferin co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARGC1A protein CTD PMID:32417366 MeIQ decreases expression ISO PPARGC1A (Homo sapiens) 6480464 2-amino-3 more ... CTD PMID:37005939 MeIQx decreases expression ISO PPARGC1A (Homo sapiens) 6480464 2-amino-3 more ... CTD PMID:37005939 melatonin multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 luzindole inhibits the reaction [Melatonin inhibits the reaction [Cadmium Chloride results in increased acetylation of PPARGC1A protein]] more ... CTD PMID:25159133 melatonin multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Melatonin inhibits the reaction [Cisplatin results in decreased expression of PPARGC1A mRNA] CTD PMID:35367536 melatonin increases expression ISO PPARGC1A (Homo sapiens) 6480464 Melatonin results in increased expression of PPARGC1A mRNA CTD PMID:33962019 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PPARGC1A protein] and Melatonin inhibits the reaction [Doxorubicin results in decreased expression of PPARGC1A protein] CTD PMID:26882442 and PMID:29966675 meldonium decreases expression EXP 6480464 3-(2 more ... CTD PMID:27559315 meldonium decreases expression ISO Ppargc1a (Mus musculus) 6480464 3-(2 more ... CTD PMID:32389661 mesalamine multiple interactions EXP 6480464 Mesalamine inhibits the reaction [Acetic Acid results in decreased expression of PPARGC1A mRNA] CTD PMID:35122774 metformin increases expression ISO PPARGC1A (Homo sapiens) 6480464 Metformin results in increased expression of PPARGC1A mRNA and Metformin results in increased expression of PPARGC1A protein CTD PMID:15864539 more ... metformin multiple interactions ISO Ppargc1a (Mus musculus) 6480464 dorsomorphin inhibits the reaction [Metformin results in increased expression of PPARGC1A mRNA] more ... CTD PMID:22117073 more ... metformin multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 PRKAA1 protein affects the reaction [Metformin results in increased expression of PPARGC1A mRNA] CTD PMID:16380484 metformin increases expression ISO Ppargc1a (Mus musculus) 6480464 Metformin results in increased expression of PPARGC1A mRNA and Metformin results in increased expression of PPARGC1A protein CTD PMID:24428821 and PMID:34302933 methamphetamine increases expression ISO Ppargc1a (Mus musculus) 6480464 Methamphetamine results in increased expression of PPARGC1A mRNA CTD PMID:26307267 methimazole increases expression EXP 6480464 Methimazole results in increased expression of PPARGC1A mRNA CTD PMID:30047161 methotrexate multiple interactions EXP 6480464 Carnitine inhibits the reaction [Methotrexate results in decreased expression of PPARGC1A protein] CTD PMID:37312617 methotrexate decreases expression EXP 6480464 Methotrexate results in decreased expression of PPARGC1A protein CTD PMID:37312617 methyl methanesulfonate increases expression ISO PPARGC1A (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of PPARGC1A mRNA CTD PMID:23649840 methylglyoxal multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Limonene co-treated with Pyruvaldehyde] results in increased expression of PPARGC1A protein more ... CTD PMID:26723916 and PMID:28986142 methylglyoxal multiple interactions EXP 6480464 [magnolol co-treated with Pyruvaldehyde] results in increased expression of PPARGC1A protein and [pimagedine co-treated with Pyruvaldehyde] results in increased expression of PPARGC1A protein CTD PMID:28919305 metoprolol multiple interactions EXP 6480464 Metoprolol inhibits the reaction [[[PPARGC1A protein results in increased expression of MEF2A mRNA] co-treated with [PPARGC1A protein results in increased expression of PPARA mRNA]] results in increased expression of CPT1B protein] more ... CTD PMID:19233164 monascin increases expression ISO Ppargc1a (Mus musculus) 6480464 monascin results in increased expression of PPARGC1A mRNA CTD PMID:24275089 mono(2-ethylhexyl) phthalate multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 mono-(2-ethylhexyl)phthalate promotes the reaction [PPARA protein binds to PPARGC1A protein] CTD PMID:20123618 mono(2-ethylhexyl) phthalate increases expression ISO Ppargc1a (Mus musculus) 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of PPARGC1A mRNA CTD PMID:25543134 and PMID:32522588 monocrotophos decreases expression EXP 6480464 Monocrotophos results in decreased expression of PPARGC1A mRNA CTD PMID:35403558 monocrotophos multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Monocrotophos results in decreased expression of PPARGC1A mRNA] CTD PMID:35403558 monosodium L-glutamate decreases expression ISO Ppargc1a (Mus musculus) 6480464 Sodium Glutamate results in decreased expression of PPARGC1A mRNA CTD PMID:19001666 and PMID:20111022 monosodium L-glutamate multiple interactions EXP 6480464 [Taurine co-treated with Sodium Glutamate] results in increased expression of PPARGC1A mRNA more ... CTD PMID:25211138 monosodium L-glutamate multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Fats more ... CTD PMID:19001666 more ... monosodium L-glutamate increases expression EXP 6480464 Sodium Glutamate results in increased expression of PPARGC1A protein CTD PMID:25211138 Morroniside multiple interactions ISO Ppargc1a (Mus musculus) 6480464 morroniside inhibits the reaction [Glucose results in decreased expression of PPARGC1A mRNA] more ... CTD PMID:34485530 myo-inositol hexakisphosphate multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [resveratrol co-treated with Quercetin co-treated with Phytic Acid] results in increased expression of PPARGC1A mRNA CTD PMID:18657603 N(6)-butyryl-cAMP multiple interactions EXP 6480464 CREM protein inhibits the reaction [monobutyryl cyclic AMP results in increased expression of PPARGC1A mRNA] CTD PMID:25381014 N(6)-butyryl-cAMP increases expression EXP 6480464 monobutyryl cyclic AMP results in increased expression of PPARGC1A mRNA CTD PMID:25381014 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO Ppargc1a (Mus musculus) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of PPARGC1A protein] and N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Norepinephrine results in increased expression of PPARGC1A mRNA] CTD PMID:16513826 and PMID:29288687 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [GW9508 inhibits the reaction [malondialdehyde-low density lipoprotein more ... CTD PMID:32347098 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of PPARGC1A mRNA] more ... CTD PMID:21775390 more ... N-acetyl-L-cysteine multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Flavonoids results in increased expression of PPARGC1A protein] and Acetylcysteine inhibits the reaction [Polystyrenes analog results in decreased expression of PPARGC1A protein] CTD PMID:23063593 and PMID:37084995 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases degradation ISO PPARGC1A (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of PPARGC1A protein CTD PMID:20860658 N-methyl-4-phenylpyridinium multiple interactions EXP 6480464 [1-Methyl-4-phenylpyridinium co-treated with epigallocatechin gallate] results in increased expression of PPARGC1A mRNA and [1-Methyl-4-phenylpyridinium co-treated with epigallocatechin gallate] results in increased expression of PPARGC1A protein CTD PMID:22742579 N-methyl-4-phenylpyridinium decreases expression ISO PPARGC1A (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of PPARGC1A protein CTD PMID:27366949 N-methyl-4-phenylpyridinium multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of and affects the localization of PPARGC1A protein more ... CTD PMID:26141122 and PMID:27366949 N-methyl-4-phenylpyridinium increases expression ISO PPARGC1A (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of PPARGC1A mRNA CTD PMID:26141122 naringin multiple interactions EXP 6480464 naringin inhibits the reaction [Ethanol results in increased expression of PPARGC1A mRNA] CTD PMID:18793633 nebivolol increases expression ISO Ppargc1a (Mus musculus) 6480464 Nebivolol results in increased expression of PPARGC1A protein CTD PMID:23886954 nebivolol multiple interactions ISO Ppargc1a (Mus musculus) 6480464 3-(2-ethylphenoxy)-1-(1 more ... CTD PMID:23886954 nickel atom decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Nickel results in decreased expression of PPARGC1A mRNA CTD PMID:24768652 and PMID:25583101 nickel atom multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [nickel chloride results in increased abundance of Nickel] which results in decreased expression of PPARGC1A mRNA and [nickel chloride results in increased abundance of Nickel] which results in decreased expression of PPARGC1A protein CTD PMID:36794572 nickel dichloride multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [nickel chloride results in increased abundance of Nickel] which results in decreased expression of PPARGC1A mRNA and [nickel chloride results in increased abundance of Nickel] which results in decreased expression of PPARGC1A protein CTD PMID:36794572 nickel sulfate multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [nickel sulfate co-treated with Particulate Matter] results in decreased expression of PPARGC1A mRNA CTD PMID:23126276 nickel sulfate decreases expression ISO Ppargc1a (Mus musculus) 6480464 nickel sulfate results in decreased expression of PPARGC1A mRNA CTD PMID:23126276 nicotinamide increases acetylation ISO PPARGC1A (Homo sapiens) 6480464 Niacinamide results in increased acetylation of PPARGC1A protein CTD PMID:19071085 nicotinamide multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Niacinamide results in decreased activity of SIRT1 protein] inhibits the reaction [SIRT1 protein results in increased expression of PPARGC1A mRNA] CTD PMID:23891692 nicotinamide multiple interactions EXP 6480464 [Niacinamide results in decreased activity of SIRT1 protein] which results in increased acetylation of PPARGC1A protein CTD PMID:23422569 nicotine multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [BMP7 protein co-treated with INS1 protein co-treated with Triiodothyronine co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with Indomethacin co-treated with Nicotine] affects the expression of PPARGC1A mRNA and [BMP7 protein co-treated with INS1 protein co-treated with Triiodothyronine co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with Indomethacin co-treated with Nicotine] affects the expression of PPARGC1A protein CTD PMID:33091441 nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of PPARGC1A mRNA and Nicotine results in decreased expression of PPARGC1A protein CTD PMID:29155039 and PMID:33091441 nicotinic acid increases expression ISO PPARGC1A (Homo sapiens) 6480464 Niacin results in increased expression of PPARGC1A mRNA CTD PMID:23056435 nitrites multiple interactions EXP 6480464 [Nitrites co-treated with Oxygen deficiency] results in increased expression of and results in decreased acetylation of PPARGC1A protein more ... CTD PMID:22892143 nitrogen dioxide decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Nitrogen Dioxide results in decreased expression of PPARGC1A mRNA CTD PMID:33064461 nitroprusside multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 Nitroprusside inhibits the reaction [Glucose deficiency results in decreased expression of PPARGC1A mRNA] CTD PMID:17855661 NMN zwitterion multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 Nicotinamide Mononucleotide inhibits the reaction [[NNT protein inhibits the reaction [NNT protein modified form results in decreased susceptibility to Cisplatin]] which results in decreased expression of PPARGC1A mRNA] CTD PMID:36336710 nordihydroguaiaretic acid increases expression EXP 329955565 NDGA increases expression of Ppara protein in liver of high fructose fed rats RGD NSC 23766 multiple interactions ISO Ppargc1a (Mus musculus) 6480464 NSC 23766 inhibits the reaction [Doxorubicin results in increased expression of PPARGC1A mRNA] CTD PMID:28710503 O-acetyl-L-carnitine increases expression ISO PPARGC1A (Homo sapiens) 6480464 Acetylcarnitine results in increased expression of PPARGC1A protein CTD PMID:20414966 O-acetyl-L-carnitine multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [Acetylcarnitine co-treated with Thioctic Acid] results in increased expression of PPARGC1A protein CTD PMID:20414966 octadecanoic acid increases expression ISO PPARGC1A (Homo sapiens) 6480464 stearic acid results in increased expression of PPARGC1A mRNA CTD PMID:23056435 olanzapine decreases expression EXP 6480464 olanzapine results in decreased expression of PPARGC1A mRNA CTD PMID:23226405 olanzapine multiple interactions EXP 6480464 [olanzapine co-treated with 1-(carboxymethylthio)tetradecane] results in decreased expression of PPARGC1A mRNA and olanzapine promotes the reaction [1-(carboxymethylthio)tetradecane results in decreased expression of PPARGC1A mRNA] CTD PMID:23226405 oleic acid multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARGC1A mRNA and FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARGC1A mRNA] CTD PMID:26847930 orientin multiple interactions ISO Ppargc1a (Mus musculus) 6480464 orientin inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PPARGC1A protein] CTD PMID:32044341 oxaloacetic acid increases expression ISO PPARGC1A (Homo sapiens) 6480464 Oxaloacetic Acid results in increased expression of PPARGC1A mRNA and Oxaloacetic Acid results in increased expression of PPARGC1A protein CTD PMID:23056435 and PMID:26811028 oxidopamine decreases expression ISO Ppargc1a (Mus musculus) 6480464 Oxidopamine results in decreased expression of PPARGC1A protein CTD PMID:29057453 oxidopamine multiple interactions ISO Ppargc1a (Mus musculus) 6480464 LY 344864 inhibits the reaction [Oxidopamine results in decreased expression of PPARGC1A protein] CTD PMID:29057453 ozone affects expression EXP 6480464 Ozone affects the expression of PPARGC1A mRNA CTD PMID:33217375 ozone multiple interactions EXP 6480464 [Ozone co-treated with Fructose] results in decreased expression of PPARGC1A mRNA more ... CTD PMID:23968387 and PMID:33217375 ozone increases expression EXP 6480464 Ozone results in increased expression of PPARGC1A mRNA CTD PMID:25838073 and PMID:35737395 ozone decreases expression EXP 6480464 Ozone results in decreased expression of PPARGC1A mRNA and Ozone results in decreased expression of PPARGC1A protein CTD PMID:23988432 and PMID:33524448 paracetamol affects expression ISO Ppargc1a (Mus musculus) 6480464 Acetaminophen affects the expression of PPARGC1A mRNA CTD PMID:17562736 paracetamol multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Acetaminophen affects the expression of and affects the localization of PPARGC1A protein and SRT1720 affects the reaction [Acetaminophen affects the expression of PPARGC1A protein] CTD PMID:28827156 paracetamol decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Acetaminophen results in decreased expression of PPARGC1A mRNA CTD PMID:29067470 paracetamol increases expression ISO Ppargc1a (Mus musculus) 6480464 Acetaminophen results in increased expression of PPARGC1A protein CTD PMID:33271250 paraquat increases expression ISO Ppargc1a (Mus musculus) 6480464 Paraquat results in increased expression of PPARGC1A protein CTD PMID:22563483 paraquat increases expression ISO PPARGC1A (Homo sapiens) 6480464 Paraquat results in increased expression of PPARGC1A mRNA CTD PMID:35182771 paraquat multiple interactions ISO Ppargc1a (Mus musculus) 6480464 AKT2 protein affects the reaction [Paraquat results in decreased expression of PPARGC1A protein] CTD PMID:28115273 paraquat decreases expression ISO Ppargc1a (Mus musculus) 6480464 Paraquat results in decreased expression of PPARGC1A protein CTD PMID:28115273 paraquat multiple interactions EXP 6480464 [Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased expression of PPARGC1A protein CTD PMID:24376630 parathion increases expression ISO Ppargc1a (Mus musculus) 6480464 Parathion results in increased expression of PPARGC1A mRNA CTD PMID:34813904 pentachlorophenol increases expression ISO Ppargc1a (Mus musculus) 6480464 Pentachlorophenol results in increased expression of PPARGC1A mRNA CTD PMID:23892564 perfluorododecanoic acid decreases expression EXP 6480464 perfluorododecanoic acid results in decreased expression of PPARGC1A protein CTD PMID:30489073 perfluorohexanesulfonic acid decreases expression ISO Ppargc1a (Mus musculus) 6480464 perfluorohexanesulfonic acid results in decreased expression of PPARGC1A mRNA CTD PMID:21705711 perfluorononanoic acid decreases expression ISO Ppargc1a (Mus musculus) 6480464 perfluoro-n-nonanoic acid results in decreased expression of PPARGC1A mRNA CTD PMID:23567314 perfluorononanoic acid increases expression ISO PPARGC1A (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in increased expression of PPARGC1A mRNA CTD PMID:32588087 perfluorooctane-1-sulfonic acid decreases expression ISO Ppargc1a (Mus musculus) 6480464 perfluorooctane sulfonic acid results in decreased expression of PPARGC1A mRNA and perfluorooctane sulfonic acid results in decreased expression of PPARGC1A protein CTD PMID:20936131 more ... perfluorooctane-1-sulfonic acid multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of PPARGC1A mRNA and [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of PPARGC1A mRNA CTD PMID:36331819 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of PPARGC1A mRNA and perfluorooctanoic acid results in increased expression of PPARGC1A protein CTD PMID:19616056 perfluorooctanoic acid decreases expression ISO Ppargc1a (Mus musculus) 6480464 perfluorooctanoic acid results in decreased expression of PPARGC1A mRNA CTD PMID:20936131 and PMID:30657992 perfluorooctanoic acid increases expression ISO Ppargc1a (Mus musculus) 6480464 perfluorooctanoic acid results in increased expression of PPARGC1A mRNA CTD PMID:22154759 peroxynitrous acid affects expression EXP 6480464 Peroxynitrous Acid affects the expression of PPARGC1A protein CTD PMID:24563852 phenobarbital increases expression ISO Ppargc1a (Mus musculus) 6480464 Phenobarbital results in increased expression of PPARGC1A mRNA CTD PMID:19270015 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of PPARGC1A mRNA CTD PMID:30047161 phenobarbital decreases expression ISO Ppargc1a (Mus musculus) 6480464 Phenobarbital results in decreased expression of PPARGC1A mRNA CTD PMID:23091169 phenylmercury acetate increases expression ISO PPARGC1A (Homo sapiens) 6480464 Phenylmercuric Acetate results in increased expression of PPARGC1A mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PPARGC1A mRNA CTD PMID:27188386 PhIP decreases expression ISO PPARGC1A (Homo sapiens) 6480464 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in decreased expression of PPARGC1A mRNA CTD PMID:37005939 Phytolaccoside E decreases expression ISO PPARGC1A (Homo sapiens) 6480464 esculentoside A results in decreased expression of PPARGC1A protein CTD PMID:36460195 picloram increases expression ISO Ppargc1a (Mus musculus) 6480464 Picloram results in increased expression of PPARGC1A mRNA CTD PMID:21318024 picoxystrobin multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 picoxystrobin inhibits the reaction [PPARGC1A protein results in increased activity of ESRRA protein] CTD PMID:30818834 pioglitazone decreases expression EXP 6480464 pioglitazone results in decreased expression of PPARGC1A mRNA CTD PMID:22456468 pioglitazone multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of PPARGC1A protein] CTD PMID:27366949 pirinixic acid multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of PPARGC1A mRNA more ... CTD PMID:17932310 more ... pirinixic acid increases expression EXP 329955450 pirinixic acid increases expression of mRNA in left ventricle myocardium of obese and hypoxic rats RGD pirinixic acid multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 pirinixic acid promotes the reaction [PPARA protein binds to PPARGC1A protein] CTD PMID:20123618 pirinixic acid increases expression ISO Ppargc1a (Mus musculus) 6480464 pirinixic acid results in increased expression of PPARGC1A mRNA CTD PMID:17275789 and PMID:18445702 platycodin D increases expression ISO Ppargc1a (Mus musculus) 6480464 platycodin D results in increased expression of PPARGC1A protein CTD PMID:26244589 and PMID:30599906 poly(vinylpyrrolidone) multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Silver Compounds co-treated with Povidone] results in decreased expression of PPARGC1A protein CTD PMID:35697184 potassium chloride increases expression EXP 6480464 Potassium Chloride results in increased expression of PPARGC1A mRNA and Potassium Chloride results in increased expression of PPARGC1A protein CTD PMID:20438809 potassium cyanide increases expression ISO Ppargc1a (Mus musculus) 6480464 Potassium Cyanide results in increased expression of PPARGC1A mRNA CTD PMID:33914522 potassium dichromate increases expression ISO PPARGC1A (Homo sapiens) 6480464 Potassium Dichromate results in increased expression of PPARGC1A mRNA CTD PMID:18332044 potassium dichromate decreases expression EXP 6480464 Potassium Dichromate results in decreased expression of PPARGC1A protein CTD PMID:32980475 potassium dichromate multiple interactions EXP 6480464 [Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in decreased expression of PPARGC1A mRNA more ... CTD PMID:32980475 and PMID:36849043 pramipexole increases expression EXP 6480464 Pramipexole results in increased expression of PPARGC1A protein CTD PMID:35868426 prazosin multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Propranolol co-treated with Prazosin] inhibits the reaction [Norepinephrine results in increased expression of PPARGC1A mRNA] CTD PMID:16513826 pregnenolone 16alpha-carbonitrile multiple interactions ISO Ppargc1a (Mus musculus) 6480464 PPARGC1A protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A11 mRNA] more ... CTD PMID:21933665 pregnenolone 16alpha-carbonitrile decreases expression ISO Ppargc1a (Mus musculus) 6480464 Pregnenolone Carbonitrile results in decreased expression of PPARGC1A mRNA CTD PMID:28903501 prochloraz multiple interactions EXP 6480464 [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of PPARGC1A mRNA CTD PMID:29038839 prochloraz increases expression EXP 6480464 prochloraz results in increased expression of PPARGC1A mRNA CTD PMID:29038839 progesterone multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [Progesterone co-treated with Estradiol] results in increased expression of PPARGC1A mRNA CTD PMID:17404688 progesterone increases expression EXP 6480464 Progesterone results in increased expression of PPARGC1A mRNA CTD PMID:23056435 progesterone increases expression ISO PPARGC1A (Homo sapiens) 6480464 Progesterone results in increased expression of PPARGC1A mRNA CTD PMID:17404688 and PMID:23056435 propiconazole decreases expression ISO Ppargc1a (Mus musculus) 6480464 propiconazole results in decreased expression of PPARGC1A mRNA CTD PMID:21278054 propionic acid increases expression ISO PPARGC1A (Homo sapiens) 6480464 propionic acid results in increased expression of PPARGC1A mRNA and propionic acid results in increased expression of PPARGC1A protein CTD PMID:31526819 propranolol multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Propranolol co-treated with Prazosin] inhibits the reaction [Norepinephrine results in increased expression of PPARGC1A mRNA] and Propranolol inhibits the reaction [Clenbuterol results in increased expression of PPARGC1A mRNA] CTD PMID:16513826 and PMID:17446185 propranolol decreases expression ISO Ppargc1a (Mus musculus) 6480464 Propranolol results in decreased expression of PPARGC1A mRNA CTD PMID:17446185 prostaglandin D2 increases expression ISO PPARGC1A (Homo sapiens) 6480464 Prostaglandin D2 results in increased expression of PPARGC1A mRNA CTD PMID:23056435 prostaglandin I2 increases expression ISO PPARGC1A (Homo sapiens) 6480464 Epoprostenol results in increased expression of PPARGC1A mRNA CTD PMID:23056435 pterostilbene increases expression ISO PPARGC1A (Homo sapiens) 6480464 pterostilbene results in increased expression of PPARGC1A mRNA CTD PMID:26443543 puerarin multiple interactions EXP 6480464 puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of PPARGC1A protein] CTD PMID:33404196 pyridaben increases expression ISO Ppargc1a (Mus musculus) 6480464 pyridaben results in increased expression of PPARGC1A mRNA CTD PMID:22563483 pyridaben multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 pyridaben inhibits the reaction [PPARGC1A protein results in increased activity of ESRRA protein] CTD PMID:30818834 pyridoxine increases expression EXP 6480464 Pyridoxine results in increased expression of PPARGC1A mRNA CTD PMID:23056435 pyridoxine increases expression ISO PPARGC1A (Homo sapiens) 6480464 Pyridoxine results in increased expression of PPARGC1A mRNA CTD PMID:23056435 pyrroloquinoline quinone increases expression ISO PPARGC1A (Homo sapiens) 6480464 PQQ Cofactor results in increased expression of PPARGC1A mRNA CTD PMID:28578007 pyrroloquinoline quinone multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 PQQ Cofactor inhibits the reaction [Rotenone results in decreased expression of PPARGC1A mRNA] and PQQ Cofactor inhibits the reaction [Rotenone results in decreased expression of PPARGC1A protein] CTD PMID:30240821 pyrroloquinoline quinone increases expression EXP 6480464 PQQ Cofactor results in increased expression of PPARGC1A mRNA CTD PMID:25843018 pyrroloquinoline quinone multiple interactions EXP 6480464 PQQ Cofactor inhibits the reaction [Rotenone results in decreased expression of PPARGC1A mRNA] more ... CTD PMID:25843018 and PMID:30240821 pyruvic acid multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [Pyruvic Acid co-treated with Glucose] results in decreased acetylation of PPARGC1A protein CTD PMID:19071085 pyruvic acid multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Pyruvic Acid inhibits the reaction [PPARGC1A protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A11 mRNA]] and SIRT1 mRNA affects the reaction [Pyruvic Acid inhibits the reaction [PPARGC1A protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A11 mRNA]]] CTD PMID:21933665 quercetin increases expression ISO Ppargc1a (Mus musculus) 6480464 Quercetin results in increased expression of PPARGC1A mRNA CTD PMID:19211721 quercetin increases expression ISO PPARGC1A (Homo sapiens) 6480464 Quercetin results in increased expression of PPARGC1A mRNA CTD PMID:32530119 quercetin multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 Tamoxifen inhibits the reaction [Quercetin results in increased expression of PPARGC1A mRNA] CTD PMID:32530119 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [aluminum lactate results in decreased expression of PPARGC1A mRNA] more ... CTD PMID:26493151 and PMID:36808657 quercetin decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Quercetin results in decreased expression of PPARGC1A mRNA CTD PMID:21632981 quercetin multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [resveratrol co-treated with Quercetin co-treated with Phytic Acid] results in increased expression of PPARGC1A mRNA more ... CTD PMID:18657603 more ... reactive oxygen species multiple interactions EXP 6480464 [Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased expression of PPARGC1A protein CTD PMID:24376630 rebaudioside A multiple interactions ISO Ppargc1a (Mus musculus) 6480464 rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA] CTD PMID:25554529 resveratrol multiple interactions ISO Ppargc1a (Mus musculus) 6480464 6-chloro-2 more ... CTD PMID:17112576 more ... resveratrol decreases acetylation ISO PPARGC1A (Homo sapiens) 6480464 Resveratrol results in decreased acetylation of PPARGC1A protein CTD PMID:34216621 resveratrol increases acetylation ISO PPARGC1A (Homo sapiens) 6480464 resveratrol results in increased acetylation of PPARGC1A protein CTD PMID:22898769 resveratrol increases expression EXP 6480464 Resveratrol results in increased expression of PPARGC1A more ... CTD PMID:20429690 more ... resveratrol decreases acetylation EXP 6480464 resveratrol results in decreased acetylation of PPARGC1A protein CTD PMID:17581637 and PMID:23790948 resveratrol multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 1H-(1 more ... CTD PMID:24041027 more ... resveratrol decreases expression ISO Ppargc1a (Mus musculus) 6480464 Resveratrol results in decreased expression of PPARGC1A mRNA more ... CTD PMID:21270273 more ... resveratrol affects response to substance ISO Ppargc1a (Mus musculus) 6480464 PPARGC1A protein affects the susceptibility to resveratrol CTD PMID:23090186 resveratrol increases activity EXP 6480464 resveratrol results in increased activity of PPARGC1A protein CTD PMID:23274094 resveratrol multiple interactions EXP 6480464 [Resveratrol results in increased activity of SIRT1 protein] which results in decreased acetylation of PPARGC1A protein more ... CTD PMID:18793633 more ... resveratrol increases activity ISO Ppargc1a (Mus musculus) 6480464 resveratrol results in increased activity of PPARGC1A protein CTD PMID:17086191 resveratrol decreases acetylation ISO Ppargc1a (Mus musculus) 6480464 resveratrol results in decreased acetylation of PPARGC1A protein CTD PMID:17581637 resveratrol increases expression ISO Ppargc1a (Mus musculus) 6480464 Resveratrol results in increased expression of PPARGC1A more ... CTD PMID:17438283 more ... resveratrol increases expression ISO PPARGC1A (Homo sapiens) 6480464 resveratrol results in increased expression of PPARGC1A more ... CTD PMID:16849586 more ... riboflavin increases expression ISO PPARGC1A (Homo sapiens) 6480464 Riboflavin results in increased expression of PPARGC1A mRNA CTD PMID:23056435 rifampicin multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA more ... CTD PMID:16857725 more ... rosmarinic acid multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 Rosmarinic Acid affects the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of PPARGC1A mRNA] CTD PMID:33476690 rotenone multiple interactions EXP 6480464 [EXOG protein co-treated with Rotenone] results in decreased expression of PPARGC1A mRNA more ... CTD PMID:25843018 more ... rotenone decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Rotenone results in decreased expression of PPARGC1A mRNA and Rotenone results in decreased expression of PPARGC1A protein CTD PMID:30240821 rotenone increases expression ISO PPARGC1A (Homo sapiens) 6480464 Rotenone results in increased expression of PPARGC1A mRNA CTD PMID:21536665 rotenone multiple interactions ISO Ppargc1a (Mus musculus) 6480464 CRTC3 protein affects the reaction [Rotenone results in increased expression of PPARGC1A mRNA] more ... CTD PMID:21536665 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of PPARGC1A mRNA and Rotenone results in decreased expression of PPARGC1A protein CTD PMID:26770656 more ... rotenone increases expression ISO Ppargc1a (Mus musculus) 6480464 Rotenone results in increased expression of PPARGC1A mRNA CTD PMID:21536665 rotenone multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [Rosiglitazone co-treated with Rotenone] results in increased expression of PPARGC1A protein more ... CTD PMID:21536665 more ... rotenone increases expression EXP 6480464 Rotenone results in increased expression of PPARGC1A mRNA CTD PMID:25843018 and PMID:28374803 S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 S-(1 and 2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in decreased expression of PPARGC1A mRNA] CTD PMID:35811015 S-adenosyl-L-homocysteine increases expression ISO PPARGC1A (Homo sapiens) 6480464 S-Adenosylhomocysteine results in increased expression of PPARGC1A mRNA CTD PMID:23056435 Salmeterol xinafoate increases expression ISO Ppargc1a (Mus musculus) 6480464 Salmeterol Xinafoate results in increased expression of PPARGC1A mRNA CTD PMID:17446185 and PMID:34601065 Salvianolic acid A multiple interactions ISO Ppargc1a (Mus musculus) 6480464 salvianolic acid A inhibits the reaction [Arsenic Trioxide results in decreased expression of PPARGC1A protein] CTD PMID:29867492 Salvianolic acid A multiple interactions EXP 6480464 salvianolic acid A inhibits the reaction [Arsenic Trioxide results in decreased expression of PPARGC1A protein] CTD PMID:29867492 salvianolic acid B multiple interactions EXP 6480464 salvianolic acid B inhibits the reaction [Ethanol results in increased acetylation of PPARGC1A protein] CTD PMID:24769256 SB 431542 multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 SB-239063 multiple interactions EXP 6480464 SB 239063 inhibits the reaction [25-hydroxyprotopanaxadiol results in increased phosphorylation of PPARGC1A protein] CTD PMID:33676887 selenium atom decreases expression ISO Ppargc1a (Mus musculus) 6480464 Selenium results in decreased expression of PPARGC1A mRNA CTD PMID:28810182 silicon atom multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Thioctic Acid co-treated with Silicon] results in increased expression of PPARGC1A protein CTD PMID:34252510 silicon dioxide decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of PPARGC1A mRNA and Silicon Dioxide results in decreased expression of PPARGC1A mRNA CTD PMID:22300531 more ... silicon dioxide decreases expression ISO Ppargc1a (Mus musculus) 6480464 Silicon Dioxide results in decreased expression of PPARGC1A mRNA CTD PMID:23221170 silver(1+) nitrate decreases expression ISO Ppargc1a (Mus musculus) 6480464 Silver Nitrate results in decreased expression of PPARGC1A protein CTD PMID:35697184 sirolimus multiple interactions EXP 6480464 Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARGC1A mRNA] more ... CTD PMID:25045214 sirolimus multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Sirolimus inhibits the reaction [[Ethylene Chlorohydrin co-treated with Lipopolysaccharides] results in increased expression of PPARGC1A mRNA] CTD PMID:31499194 sirtinol multiple interactions ISO Ppargc1a (Mus musculus) 6480464 sirtinol inhibits the reaction [genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of PPARGC1A protein]] CTD PMID:28477916 sirtinol multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 sirtinol inhibits the reaction [Melatonin inhibits the reaction [Cadmium Chloride results in increased acetylation of PPARGC1A protein]] and sirtinol inhibits the reaction [Melatonin inhibits the reaction [Cadmium results in increased acetylation of PPARGC1A protein]] CTD PMID:25159133 sirtinol multiple interactions EXP 6480464 sirtinol inhibits the reaction [resveratrol results in increased expression of PPARGC1A protein] CTD PMID:24395567 sodium arsenate increases expression ISO Ppargc1a (Mus musculus) 6480464 sodium arsenate results in increased expression of PPARGC1A mRNA CTD PMID:21795629 and PMID:30503583 sodium arsenate multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of PPARGC1A mRNA] and ferulic acid inhibits the reaction [sodium arsenate results in increased expression of PPARGC1A mRNA] CTD PMID:30503583 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of PPARGC1A mRNA and sodium arsenite results in decreased expression of PPARGC1A protein CTD PMID:26767369 and PMID:27425645 sodium arsenite increases expression ISO Ppargc1a (Mus musculus) 6480464 sodium arsenite results in increased expression of PPARGC1A mRNA CTD PMID:19822182 and PMID:37682722 sodium arsenite decreases expression ISO Ppargc1a (Mus musculus) 6480464 sodium arsenite results in decreased expression of PPARGC1A mRNA and sodium arsenite results in decreased expression of PPARGC1A protein CTD PMID:25979314 and PMID:31532247 sodium arsenite multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of PPARGC1A protein more ... CTD PMID:25979314 and PMID:32045263 sodium fluoride decreases expression ISO Ppargc1a (Mus musculus) 6480464 Sodium Fluoride results in decreased expression of PPARGC1A mRNA and Sodium Fluoride results in decreased expression of PPARGC1A protein CTD PMID:37739047 sodium fluoride multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Thioctic Acid inhibits the reaction [Sodium Fluoride results in decreased expression of PPARGC1A mRNA] CTD PMID:37739047 sodium hydrogensulfite multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of PPARGC1A mRNA] CTD PMID:26980303 sodium hydrogensulfite decreases expression EXP 6480464 sodium bisulfite results in decreased expression of PPARGC1A mRNA and sodium bisulfite results in decreased expression of PPARGC1A protein CTD PMID:26980303 splitomicin multiple interactions EXP 6480464 splitomicin inhibits the reaction [[Nitrites co-treated with Oxygen deficiency] results in increased expression of PPARGC1A mRNA] CTD PMID:22892143 staurosporine multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Hydrogen Peroxide co-treated with Staurosporine] results in increased acetylation of PPARGC1A protein and resveratrol inhibits the reaction [[Hydrogen Peroxide co-treated with Staurosporine] results in increased acetylation of PPARGC1A protein] CTD PMID:23293585 steviol multiple interactions ISO Ppargc1a (Mus musculus) 6480464 steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA] CTD PMID:25554529 stevioside multiple interactions ISO Ppargc1a (Mus musculus) 6480464 stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA] CTD PMID:25554529 streptozocin decreases expression EXP 6480464 Streptozocin results in decreased expression of PPARGC1A mRNA and Streptozocin results in decreased expression of PPARGC1A protein CTD PMID:25246140 more ... streptozocin increases expression ISO Ppargc1a (Mus musculus) 6480464 Streptozocin results in increased expression of PPARGC1A mRNA CTD PMID:23319174 streptozocin multiple interactions ISO Ppargc1a (Mus musculus) 6480464 [Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARGC1A mRNA more ... CTD PMID:21381899 more ... streptozocin decreases expression ISO Ppargc1a (Mus musculus) 6480464 Streptozocin results in decreased expression of PPARGC1A protein CTD PMID:21381899 streptozocin multiple interactions EXP 6480464 ferulic acid inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A protein] more ... CTD PMID:25246140 more ... sulfadimethoxine increases expression EXP 6480464 Sulfadimethoxine results in increased expression of PPARGC1A mRNA CTD PMID:30047161 sulforaphane increases expression ISO PPARGC1A (Homo sapiens) 6480464 sulforaphane results in increased expression of PPARGC1A protein CTD PMID:27993529 sulforaphane increases expression ISO Ppargc1a (Mus musculus) 6480464 sulforaphane results in increased expression of PPARGC1A mRNA CTD PMID:30529165 sulfur dioxide decreases expression EXP 6480464 Sulfur Dioxide results in decreased expression of PPARGC1A mRNA and Sulfur Dioxide results in decreased expression of PPARGC1A protein CTD PMID:26980303 sunitinib decreases expression ISO Ppargc1a (Mus musculus) 6480464 sunitinib results in decreased expression of PPARGC1A protein CTD PMID:30031043 T-2 toxin multiple interactions ISO Ppargc1a (Mus musculus) 6480464 6-hydroxy-2 more ... CTD PMID:27363784 T-2 toxin multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of PPARGC1A mRNA] and NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of PPARGC1A protein] CTD PMID:35842139 T-2 toxin decreases expression ISO PPARGC1A (Homo sapiens) 6480464 T-2 Toxin results in decreased expression of PPARGC1A mRNA and T-2 Toxin results in decreased expression of PPARGC1A protein CTD PMID:35842139 T-2 toxin increases expression EXP 6480464 T-2 Toxin results in increased expression of PPARGC1A mRNA CTD PMID:29870751 T-2 toxin decreases expression ISO Ppargc1a (Mus musculus) 6480464 T-2 Toxin results in decreased expression of PPARGC1A protein CTD PMID:27363784 tamoxifen multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [Tamoxifen co-treated with bisphenol A] results in increased expression of PPARGC1A mRNA more ... CTD PMID:16889744 more ... tamoxifen decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Tamoxifen results in decreased expression of PPARGC1A mRNA CTD PMID:32530119 tamoxifen increases expression ISO PPARGC1A (Homo sapiens) 6480464 Tamoxifen results in increased expression of PPARGC1A mRNA CTD PMID:27089845 taurine multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of PPARGC1A mRNA] CTD PMID:30362509 taurine multiple interactions EXP 6480464 [Taurine co-treated with Sodium Glutamate] results in increased expression of PPARGC1A mRNA more ... CTD PMID:25211138 tauroursodeoxycholic acid multiple interactions EXP 6480464 ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA] and ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein] CTD PMID:20165829 tauroursodeoxycholic acid multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA] and ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein] CTD PMID:20165829 telmisartan multiple interactions ISO Ppargc1a (Mus musculus) 6480464 telmisartan inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A protein] CTD PMID:21381899 tert-butyl hydroperoxide decreases expression ISO PPARGC1A (Homo sapiens) 6480464 tert-Butylhydroperoxide results in decreased expression of PPARGC1A protein CTD PMID:25522270 tert-butyl hydroperoxide decreases response to substance ISO Ppargc1a (Mus musculus) 6480464 PPARGC1A protein results in decreased susceptibility to tert-Butylhydroperoxide CTD PMID:17460188 tert-butyl hydroperoxide multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 AICA ribonucleotide inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of PPARGC1A protein] more ... CTD PMID:25522270 testosterone multiple interactions EXP 6480464 Norepinephrine inhibits the reaction [Testosterone results in decreased expression of PPARGC1A mRNA] and Testosterone inhibits the reaction [Dexamethasone results in decreased expression of PPARGC1A protein] CTD PMID:16954335 and PMID:21094144 testosterone decreases expression EXP 6480464 Testosterone results in decreased expression of PPARGC1A mRNA CTD PMID:16954335 testosterone increases expression ISO Ppargc1a (Mus musculus) 6480464 Testosterone results in increased expression of PPARGC1A mRNA CTD PMID:21045173 testosterone enanthate increases expression EXP 6480464 testosterone enanthate results in increased expression of PPARGC1A mRNA CTD PMID:25603467 tetrachloromethane multiple interactions EXP 6480464 Melatonin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PPARGC1A protein] and schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of PPARGC1A mRNA] CTD PMID:26882442 and PMID:31150632 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of PPARGC1A mRNA and Carbon Tetrachloride results in decreased expression of PPARGC1A protein CTD PMID:26882442 and PMID:31150632 tetradecanoic acid increases expression ISO PPARGC1A (Homo sapiens) 6480464 Myristic Acid results in increased expression of PPARGC1A mRNA CTD PMID:23056435 tetraphene decreases expression ISO Ppargc1a (Mus musculus) 6480464 benz(a)anthracene results in decreased expression of PPARGC1A mRNA CTD PMID:26377693 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of PPARGC1A mRNA CTD PMID:34492290 titanium dioxide decreases expression ISO Ppargc1a (Mus musculus) 6480464 titanium dioxide results in decreased expression of PPARGC1A mRNA CTD PMID:23557971 topotecan multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 Topotecan inhibits the reaction [PPARGC1A protein results in increased activity of ESRRA protein] CTD PMID:30818834 trichlopyr increases expression ISO Ppargc1a (Mus musculus) 6480464 triclopyr results in increased expression of PPARGC1A mRNA CTD PMID:21318024 trichlopyr multiple interactions ISO Ppargc1a (Mus musculus) 6480464 arginyl-2 and '6'-dimethyltyrosyl-lysyl-phenylalaninamide promotes the reaction [triclopyr results in increased expression of PPARGC1A mRNA] CTD PMID:21318024 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of PPARGC1A mRNA CTD PMID:33387578 trichostatin A increases expression ISO PPARGC1A (Homo sapiens) 6480464 trichostatin A results in increased expression of PPARGC1A mRNA CTD PMID:24935251 triclosan decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Triclosan results in decreased expression of PPARGC1A mRNA CTD PMID:30510588 trifloxystrobin multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 trifloxystrobin inhibits the reaction [PPARGC1A protein results in increased activity of ESRRA protein] CTD PMID:30818834 trilobatin multiple interactions EXP 6480464 trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of PPARGC1A protein] CTD PMID:30104959 triphenylstannane decreases expression EXP 6480464 triphenyltin results in decreased expression of PPARGC1A protein CTD PMID:31765896 triphenylstannane decreases expression ISO PPARGC1A (Homo sapiens) 6480464 triphenyltin results in decreased expression of PPARGC1A protein CTD PMID:31765896 Triptolide decreases expression ISO Ppargc1a (Mus musculus) 6480464 triptolide results in decreased expression of PPARGC1A mRNA CTD PMID:32835833 Triptolide multiple interactions EXP 6480464 7 more ... CTD PMID:36436616 Triptolide multiple interactions ISO Ppargc1a (Mus musculus) 6480464 resveratrol inhibits the reaction [triptolide affects the localization of and results in increased acetylation of PPARGC1A protein] more ... CTD PMID:29723566 troglitazone multiple interactions ISO Ppargc1a (Mus musculus) 6480464 PPARG protein promotes the reaction [troglitazone results in increased expression of PPARGC1A mRNA] CTD PMID:16513826 troglitazone increases expression EXP 6480464 troglitazone results in increased expression of PPARGC1A mRNA CTD PMID:14563825 troglitazone increases expression ISO PPARGC1A (Homo sapiens) 6480464 troglitazone results in increased expression of PPARGC1A mRNA CTD PMID:20860658 troglitazone increases degradation ISO PPARGC1A (Homo sapiens) 6480464 troglitazone results in increased degradation of PPARGC1A protein CTD PMID:20860658 troglitazone decreases expression ISO PPARGC1A (Homo sapiens) 6480464 troglitazone results in decreased expression of PPARGC1A protein CTD PMID:20860658 troglitazone multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 PPARGC1A protein inhibits the reaction [troglitazone results in decreased expression of ATP5F1B mRNA] and PPARGC1A protein inhibits the reaction [troglitazone results in decreased expression of TFAM mRNA] CTD PMID:20860658 troglitazone decreases response to substance ISO PPARGC1A (Homo sapiens) 6480464 PPARGC1A protein results in decreased susceptibility to troglitazone CTD PMID:20860658 troglitazone increases expression ISO Ppargc1a (Mus musculus) 6480464 troglitazone results in increased expression of PPARGC1A mRNA CTD PMID:16513826 tunicamycin increases expression ISO Ppargc1a (Mus musculus) 6480464 Tunicamycin results in increased expression of PPARGC1A mRNA CTD PMID:22414386 tunicamycin multiple interactions ISO Ppargc1a (Mus musculus) 6480464 CEBPB protein inhibits the reaction [Tunicamycin results in decreased expression of PPARGC1A protein] CTD PMID:28482072 tunicamycin decreases expression ISO Ppargc1a (Mus musculus) 6480464 Tunicamycin results in decreased expression of PPARGC1A mRNA and Tunicamycin results in decreased expression of PPARGC1A protein CTD PMID:28482072 UDP-alpha-D-glucuronic acid increases expression ISO PPARGC1A (Homo sapiens) 6480464 Uridine Diphosphate Glucuronic Acid results in increased expression of PPARGC1A mRNA CTD PMID:23056435 valproic acid increases expression ISO Ppargc1a (Mus musculus) 6480464 Valproic Acid results in increased expression of PPARGC1A mRNA CTD PMID:24489787 valproic acid decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Valproic Acid results in decreased expression of PPARGC1A mRNA CTD PMID:27089845 valproic acid increases expression ISO PPARGC1A (Homo sapiens) 6480464 Valproic Acid results in increased expression of PPARGC1A mRNA CTD PMID:23179753 more ... valproic acid multiple interactions ISO PPARGC1A (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PPARGC1A mRNA CTD PMID:27188386 valproic acid decreases methylation ISO PPARGC1A (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of PPARGC1A gene CTD PMID:29154799 valproic acid affects expression ISO PPARGC1A (Homo sapiens) 6480464 Valproic Acid affects the expression of PPARGC1A mRNA CTD PMID:25979313 vancomycin increases expression ISO Ppargc1a (Mus musculus) 6480464 Vancomycin results in increased expression of PPARGC1A mRNA CTD PMID:18930951 vincristine decreases expression EXP 6480464 Vincristine results in decreased expression of PPARGC1A protein CTD PMID:36808657 vincristine multiple interactions EXP 6480464 Quercetin inhibits the reaction [Vincristine results in decreased expression of PPARGC1A protein] CTD PMID:36808657 vorinostat increases expression ISO PPARGC1A (Homo sapiens) 6480464 vorinostat results in increased expression of PPARGC1A mRNA CTD PMID:27188386 ziram decreases expression EXP 6480464 Ziram results in decreased expression of PPARGC1A protein CTD PMID:30422632 zoledronic acid decreases expression ISO PPARGC1A (Homo sapiens) 6480464 Zoledronic Acid results in decreased expression of PPARGC1A mRNA and Zoledronic Acid results in decreased expression of PPARGC1A protein CTD PMID:24714768 and PMID:28871336 zoledronic acid multiple interactions ISO Ppargc1a (Mus musculus) 6480464 Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of PPARGC1A mRNA] and SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in decreased expression of PPARGC1A mRNA] CTD PMID:28871336 zoledronic acid decreases expression ISO Ppargc1a (Mus musculus) 6480464 zoledronic acid results in decreased expression of PPARGC1A mRNA CTD PMID:28871336