Gene: Mdh1 (malate dehydrogenase 1) Rattus norvegicus
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Symbol: Mdh1
Name: malate dehydrogenase 1
Description: ENCODES a protein that exhibits L-malate dehydrogenase activity; malate dehydrogenase activity; NAD binding; INVOLVED IN malate metabolic process; NAD metabolic process; NADH metabolic process; PARTICIPATES IN Leigh disease pathway; nicotinamide adenine dinucleotide metabolic pathway; primary hyperoxaluria type 2 pathway; ASSOCIATED WITH adult respiratory distress syndrome (ortholog); Bardet-Biedl syndrome (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN myelin sheath (ortholog); INTERACTS WITH (+)-menthofuran; 1-benzylpiperazine; 1-naphthyl isothiocyanate
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cytosolic malate dehydrogenase; malate dehydrogenase 1, NAD (soluble); malate dehydrogenase soluble; malate dehydrogenase, cytoplasmic; malate dehydrogenase, peroxisomal; malate dehydrogenase, soluble; Malate dehydrogenase-like enzyme; Mdhl; MDL1; Mor2
Orthologs:
Homo sapiens (human) : MDH1 (malate dehydrogenase 1)  HGNC  Alliance
Mus musculus (house mouse) : Mdh1 (malate dehydrogenase 1, NAD (soluble))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mdh1 (malate dehydrogenase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MDH1 (malate dehydrogenase 1)
Canis lupus familiaris (dog) : MDH1 (malate dehydrogenase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mdh1 (malate dehydrogenase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.014106,378,349 - 106,393,642 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.014106,449,337 - 106,463,995 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414102,259,130 - 102,273,788 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.114102,278,343 - 102,292,999 (-)NCBI
Celera1494,639,971 - 94,655,156 (-)NCBICelera
Cytogenetic Map14q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Mdh1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3072
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-06-05
Status: ACTIVE