Gene: Mdh1 (malate dehydrogenase 1) Rattus norvegicus
Symbol: Mdh1
Name: malate dehydrogenase 1
Description: ENCODES a protein that exhibits L-malate dehydrogenase activity; malate dehydrogenase activity; NAD binding; INVOLVED IN malate metabolic process; NAD metabolic process; NADH metabolic process; PARTICIPATES IN Leigh disease pathway; nicotinamide adenine dinucleotide metabolic pathway; primary hyperoxaluria type 2 pathway; ASSOCIATED WITH Liver Injury; adult respiratory distress syndrome (ortholog); Bardet-Biedl syndrome (ortholog); FOUND IN myelin sheath (ortholog); INTERACTS WITH (+)-menthofuran; 1-benzylpiperazine; 1-naphthyl isothiocyanate
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cytosolic malate dehydrogenase; malate dehydrogenase 1, NAD (soluble); malate dehydrogenase soluble; malate dehydrogenase, cytoplasmic; malate dehydrogenase, peroxisomal; malate dehydrogenase, soluble; Malate dehydrogenase-like enzyme; Mdhl; MDL1; Mor2
Homo sapiens (human) : MDH1 (malate dehydrogenase 1)  HGNC  Alliance
Mus musculus (house mouse) : Mdh1 (malate dehydrogenase 1, NAD (soluble))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mdh1 (malate dehydrogenase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MDH1 (malate dehydrogenase 1)
Canis lupus familiaris (dog) : MDH1 (malate dehydrogenase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mdh1 (malate dehydrogenase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.014106,378,349 - 106,393,642 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.014106,449,337 - 106,463,995 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414102,259,130 - 102,273,788 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.114102,278,343 - 102,292,999 (-)NCBI
Celera1494,639,971 - 94,655,156 (-)NCBICelera
Cytogenetic Map14q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Mdh1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3072
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-08-21
Status: ACTIVE