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Gene: Mdh1 (malate dehydrogenase 1) Rattus norvegicus
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Symbol: Mdh1
Name: malate dehydrogenase 1
Description: Exhibits L-malate dehydrogenase activity and NAD binding activity. Involved in NAD metabolic process; NADH metabolic process; and dicarboxylic acid metabolic process. Predicted to localize to the cytosol. Orthologous to human MDH1 (malate dehydrogenase 1); PARTICIPATES IN Leigh disease pathway; nicotinamide adenine dinucleotide metabolic pathway; primary hyperoxaluria type 2 pathway; INTERACTS WITH (+)-menthofuran; 1-benzylpiperazine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cytosolic malate dehydrogenase; malate dehydrogenase 1, NAD (soluble); malate dehydrogenase soluble; malate dehydrogenase, cytoplasmic; malate dehydrogenase, peroxisomal; malate dehydrogenase, soluble; Malate dehydrogenase-like enzyme; Mdhl; MDL1; Mor2
Orthologs:
Homo sapiens (human) : MDH1 (malate dehydrogenase 1)  HGNC  Alliance
Mus musculus (house mouse) : Mdh1 (malate dehydrogenase 1, NAD (soluble))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mdh1 (malate dehydrogenase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MDH1 (malate dehydrogenase 1)
Canis lupus familiaris (dog) : MDH1 (malate dehydrogenase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mdh1 (malate dehydrogenase 1)
Sus scrofa (pig) : MDH1 (malate dehydrogenase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.014106,378,349 - 106,393,642 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14106,378,942 - 106,393,670 (-)Ensembl
Rnor_5.014106,449,337 - 106,463,995 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414102,259,130 - 102,273,788 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.114102,278,343 - 102,292,999 (-)NCBI
Celera1494,639,971 - 94,655,156 (-)NCBICelera
Cytogenetic Map14q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Mdh1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3072
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.