Gene: Bcl11a (BAF chromatin remodeling complex subunit BCL11A) Rattus norvegicus
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Symbol:
Bcl11a
Name:
BAF chromatin remodeling complex subunit BCL11A
Description:
Exhibits protein kinase binding activity. Involved in cellular response to L-glutamate; negative regulation of nervous system development; and positive regulation of gene expression. Localizes to the cytoplasm; nucleus; and postsynaptic density. Human ortholog(s) of this gene implicated in autism spectrum disorder; beta thalassemia; schizophrenia; and sickle cell anemia. Orthologous to human BCL11A (BAF chromatin remodeling complex subunit BCL11A); INTERACTS WITH 1,3-dinitrobenzene; 2-methoxyethanol; amphetamine.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
B-cell CLL/lymphoma 11A; B-cell CLL/lymphoma 11A (zinc finger protein); B-cell lymphoma/leukemia 11A; BCL11A, BAF complex component; LOC305589
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
BCL11A (BAF chromatin remodeling complex subunit BCL11A) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):
Bcl11a (B cell CLL/lymphoma 11A (zinc finger protein)) HGNC
Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Bcl11a (BAF chromatin remodeling complex subunit BCL11A) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
BCL11A (BAF chromatin remodeling complex subunit BCL11A) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
BCL11A (BAF chromatin remodeling complex subunit BCL11A) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Bcl11a (BAF chromatin remodeling complex subunit BCL11A) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
BCL11A (BAF chromatin remodeling complex subunit BCL11A) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
BCL11B (BAF chromatin remodeling complex subunit BCL11B) HGNC
OrthoDB, OrthoMCL
Alliance orthologs 3
Homo sapiens (human):
BCL11A (BAF chromatin remodeling complex subunit BCL11A)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Mus musculus (house mouse):
Bcl11a (B cell CLL/lymphoma 11A (zinc finger protein))
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Danio rerio (zebrafish):
bcl11aa (BAF chromatin remodeling complex subunit BCL11A a)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Danio rerio (zebrafish):
bcl11ab (BAF chromatin remodeling complex subunit BCL11A b)
Alliance
DIOPT (OrthoFinder, PANTHER, PhylomeDB, TreeFam)
Drosophila melanogaster (fruit fly):
CG9650
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Caenorhabditis elegans (roundworm):
bcl-11
Alliance
DIOPT (Ensembl Compara, InParanoid, OrthoFinder)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 14 108,826,717 - 108,921,197 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 14 108,826,831 - 108,921,669 (+) Ensembl Rnor_5.0 14 108,546,630 - 108,641,101 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 14 105,002,744 - 105,088,365 (+) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 14 105,021,975 - 105,116,487 (+) NCBI Celera 14 96,996,223 - 97,081,419 (+) NCBI Celera Cytogenetic Map 14 q22 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - ClinVar
Agenesis of Corpus Callosum ISO RGD:1320527 8554872 ClinVar Annotator: match by term: Agenesis of corpus callosum ClinVar Developmental Disabilities ISO RGD:1320527 8554872 ClinVar Annotator: match by term: Global developmental delay ClinVar PMID:25741868 genetic disease ISO RGD:1320527 8554872 ClinVar Annotator: match by term: Inborn genetic diseases ClinVar PMID:10744719 more ... genetic disease ISO RGD:1320527 8554872 ClinVar Annotator: match by term: Inborn genetic diseases ClinVar PMID:10744719 more ... INTELLECTUAL DEVELOPMENTAL DISORDER WITH PERSISTENCE OF FETAL HEMOGLOBIN ISO RGD:1320527 8554872 ClinVar Annotator: match by term: INTELLECTUAL DEVELOPMENTAL DISORDER WITH PERSISTENCE OF FETAL HEMOGLOBIN ClinVar PMID:27453576 INTELLECTUAL DEVELOPMENTAL DISORDER WITH PERSISTENCE OF FETAL HEMOGLOBIN ISO RGD:1320527 8554872 ClinVar Annotator: match by term: Intellectual developmental disorder with persistence of fetal hemoglobin ClinVar PMID:25741868 , PMID:27453576 INTELLECTUAL DEVELOPMENTAL DISORDER WITH PERSISTENCE OF FETAL HEMOGLOBIN ISO RGD:1320527 8554872 ClinVar Annotator: match by term: Intellectual developmental disorder with persistence of fetal hemoglobin ClinVar INTELLECTUAL DEVELOPMENTAL DISORDER WITH PERSISTENCE OF FETAL HEMOGLOBIN ISO RGD:1320527 8554872 ClinVar Annotator: match by term: Intellectual developmental disorder with persistence of fetal hemoglobin ClinVar PMID:25741868 INTELLECTUAL DEVELOPMENTAL DISORDER WITH PERSISTENCE OF FETAL HEMOGLOBIN ISO RGD:1320527 8554872 ClinVar Annotator: match by term: Intellectual developmental disorder with persistence of fetal hemoglobin ClinVar PMID:10744719 more ... Marfanoid Mental Retardation Syndrome, Autosomal ISO RGD:1320527 8554872 ClinVar Annotator: match by term: Marfanoid habitus and intellectual disability ClinVar PMID:25741868
Imported Annotations - CTD
adenoid cystic carcinoma ISO RGD:1320527 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:16762588 apraxia ISO RGD:1320527 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:27120335 Language Development Disorders ISO RGD:1320527 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:27120335 polycystic ovary syndrome ISO RGD:1320527 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:21411543 Salivary Gland Neoplasms ISO RGD:1320527 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:16762588 Imported Annotations - OMIM
INTELLECTUAL DEVELOPMENTAL DISORDER WITH PERSISTENCE OF FETAL HEMOGLOBIN ISO RGD:1320527 7240710 OMIM
1,3-dinitrobenzene decreases expression EXP 6480464 3-dinitrobenzene results in decreased expression of BCL11A mRNA CTD PMID:21983209 17alpha-ethynylestradiol multiple interactions ISO RGD:1320528 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of BCL11A mRNA CTD PMID:17942748 17beta-estradiol multiple interactions ISO RGD:1320527 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of BCL11A mRNA CTD PMID:20660070 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1320528 6480464 Tetrachlorodibenzodioxin results in decreased expression of BCL11A mRNA CTD PMID:15652763 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1320528 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of BCL11A mRNA CTD PMID:17942748 2-methoxyethanol decreases expression EXP 6480464 methyl cellosolve results in decreased expression of BCL11A mRNA CTD PMID:21061450 2-methylcholine affects expression ISO RGD:1320527 6480464 beta-methylcholine affects the expression of BCL11A mRNA CTD PMID:21179406 3,4-methylenedioxymethamphetamine increases methylation ISO RGD:1320528 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased methylation of BCL11A promoter CTD PMID:26251327 3,4-methylenedioxymethamphetamine decreases expression ISO RGD:1320528 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of BCL11A mRNA CTD PMID:26251327 4,4'-sulfonyldiphenol increases expression ISO RGD:1320527 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of BCL11A mRNA CTD PMID:25912373 aflatoxin B1 increases methylation ISO RGD:1320527 6480464 Aflatoxin B1 results in increased methylation of BCL11A intron CTD PMID:30157460 aflatoxin B2 increases methylation ISO RGD:1320527 6480464 aflatoxin B2 results in increased methylation of BCL11A intron CTD PMID:30157460 all-trans-retinoic acid decreases expression ISO RGD:1320527 6480464 Tretinoin results in decreased expression of BCL11A mRNA CTD PMID:15498508 amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of BCL11A mRNA CTD PMID:30779732 antirheumatic drug decreases expression ISO RGD:1320527 6480464 Antirheumatic Agents results in decreased expression of BCL11A mRNA CTD PMID:24449571 arsane affects methylation ISO RGD:1320527 6480464 Arsenic affects the methylation of BCL11A gene CTD PMID:25304211 arsenic atom affects methylation ISO RGD:1320527 6480464 Arsenic affects the methylation of BCL11A gene CTD PMID:25304211 belinostat increases expression ISO RGD:1320527 6480464 belinostat results in increased expression of BCL11A mRNA CTD PMID:26272509 belinostat multiple interactions ISO RGD:1320527 6480464 [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BCL11A mRNA CTD PMID:27188386 benzo[a]pyrene decreases expression ISO RGD:1320528 6480464 Benzo(a)pyrene results in decreased expression of BCL11A mRNA CTD PMID:21569818 benzo[a]pyrene decreases expression ISO RGD:1320527 6480464 Benzo(a)pyrene results in decreased expression of BCL11A mRNA CTD PMID:20064835 bis(2-ethylhexyl) phthalate increases expression ISO RGD:1320527 6480464 Diethylhexyl Phthalate results in increased expression of BCL11A mRNA CTD PMID:31163220 bisphenol A decreases expression ISO RGD:1320527 6480464 bisphenol A results in decreased expression of BCL11A mRNA CTD PMID:22576693 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of BCL11A gene CTD PMID:28505145 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of BCL11A mRNA CTD PMID:25181051 buta-1,3-diene decreases expression ISO RGD:1320528 6480464 1, 3-butadiene results in decreased expression of BCL11A mRNA CTD PMID:29038090 butanal increases expression ISO RGD:1320527 6480464 butyraldehyde results in increased expression of BCL11A mRNA CTD PMID:26079696 carbon nanotube increases expression ISO RGD:1320528 6480464 Nanotubes, Carbon results in increased expression of BCL11A mRNA CTD PMID:25554681 casticin decreases expression ISO RGD:1320528 6480464 casticin results in decreased expression of BCL11A mRNA CTD PMID:28444820 chloroprene decreases expression ISO RGD:1320528 6480464 Chloroprene results in decreased expression of BCL11A mRNA CTD PMID:23125180 choline multiple interactions ISO RGD:1320528 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BCL11A gene CTD PMID:20938992 chrysene increases expression ISO RGD:1320528 6480464 chrysene results in increased expression of BCL11A mRNA CTD PMID:26377693 cobalt dichloride decreases expression ISO RGD:1320528 6480464 cobaltous chloride results in decreased expression of BCL11A mRNA CTD PMID:21139344 copper atom multiple interactions ISO RGD:1320527 6480464 [NSC 689534 binds to Copper] which results in decreased expression of BCL11A mRNA CTD PMID:20971185 copper(0) multiple interactions ISO RGD:1320527 6480464 [NSC 689534 binds to Copper] which results in decreased expression of BCL11A mRNA CTD PMID:20971185 dichloroacetic acid increases expression ISO RGD:1320528 6480464 Dichloroacetic Acid results in increased expression of BCL11A mRNA CTD PMID:28962523 dioxygen multiple interactions ISO RGD:1320528 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of BCL11A mRNA CTD PMID:30529165 diuron decreases expression EXP 6480464 Diuron results in decreased expression of BCL11A mRNA CTD PMID:21551480 dorsomorphin multiple interactions ISO RGD:1320527 6480464 [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 elemental selenium decreases expression ISO RGD:1320527 6480464 Selenium results in decreased expression of BCL11A mRNA CTD PMID:19244175 entinostat multiple interactions ISO RGD:1320527 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BCL11A mRNA CTD PMID:27188386 entinostat increases expression ISO RGD:1320527 6480464 entinostat results in increased expression of BCL11A mRNA CTD PMID:26272509 ethanol affects splicing ISO RGD:1320528 6480464 Ethanol affects the splicing of BCL11A mRNA CTD PMID:30319688 folic acid multiple interactions ISO RGD:1320528 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BCL11A gene CTD PMID:20938992 formaldehyde decreases expression ISO RGD:1320527 6480464 Formaldehyde results in decreased expression of BCL11A mRNA CTD PMID:20655997 , PMID:27664576 geraniol decreases expression ISO RGD:1320527 6480464 geraniol results in decreased expression of BCL11A mRNA CTD PMID:27683099 hydroquinone decreases expression ISO RGD:1320527 6480464 hydroquinone results in decreased expression of BCL11A mRNA CTD PMID:31256213 L-methionine multiple interactions ISO RGD:1320528 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BCL11A gene CTD PMID:20938992 mercury dibromide increases expression ISO RGD:1320527 6480464 mercuric bromide results in increased expression of BCL11A mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO RGD:1320527 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BCL11A mRNA CTD PMID:27188386 methylmercury chloride increases expression ISO RGD:1320527 6480464 methylmercuric chloride results in increased expression of BCL11A mRNA CTD PMID:28001369 nickel atom decreases expression ISO RGD:1320527 6480464 Nickel results in decreased expression of BCL11A mRNA CTD PMID:24768652 nickel sulfate decreases expression ISO RGD:1320527 6480464 nickel sulfate results in decreased expression of BCL11A mRNA CTD PMID:18651567 oxaliplatin decreases expression EXP 6480464 oxaliplatin results in decreased expression of BCL11A mRNA CTD PMID:25729387 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of BCL11A mRNA CTD PMID:25729387 panobinostat multiple interactions ISO RGD:1320527 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BCL11A mRNA CTD PMID:27188386 panobinostat increases expression ISO RGD:1320527 6480464 panobinostat results in increased expression of BCL11A mRNA CTD PMID:26272509 paracetamol affects expression ISO RGD:1320528 6480464 Acetaminophen affects the expression of BCL11A mRNA CTD PMID:17562736 paracetamol increases expression ISO RGD:1320527 6480464 Acetaminophen results in increased expression of BCL11A mRNA CTD PMID:26690555 pentanal increases expression ISO RGD:1320527 6480464 pentanal results in increased expression of BCL11A mRNA CTD PMID:26079696 phenylmercury acetate increases expression ISO RGD:1320527 6480464 Phenylmercuric Acetate results in increased expression of BCL11A mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:1320527 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BCL11A mRNA CTD PMID:27188386 pioglitazone decreases expression ISO RGD:1320527 6480464 Pioglitazone results in decreased expression of BCL11A mRNA CTD PMID:30031879 progesterone multiple interactions ISO RGD:1320527 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of BCL11A mRNA CTD PMID:20660070 propanal increases expression ISO RGD:1320527 6480464 propionaldehyde results in increased expression of BCL11A mRNA CTD PMID:26079696 SB 431542 multiple interactions ISO RGD:1320527 6480464 [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 selenium atom decreases expression ISO RGD:1320527 6480464 Selenium results in decreased expression of BCL11A mRNA CTD PMID:19244175 silicon dioxide decreases expression ISO RGD:1320527 6480464 Silicon Dioxide results in decreased expression of BCL11A mRNA CTD PMID:25351596 tamibarotene decreases expression ISO RGD:1320527 6480464 tamibarotene results in decreased expression of BCL11A mRNA CTD PMID:15498508 titanium dioxide increases expression ISO RGD:1320528 6480464 titanium dioxide results in increased expression of BCL11A mRNA CTD PMID:23557971 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of BCL11A mRNA CTD PMID:25729387 topotecan decreases expression EXP 6480464 Topotecan results in decreased expression of BCL11A mRNA CTD PMID:25729387 Tributyltin oxide increases expression ISO RGD:1320528 6480464 bis(tri-n-butyltin)oxide results in increased expression of BCL11A mRNA CTD PMID:18958704 trichostatin A increases expression ISO RGD:1320527 6480464 trichostatin A results in increased expression of BCL11A mRNA CTD PMID:24935251 , PMID:26272509 trichostatin A multiple interactions ISO RGD:1320527 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BCL11A mRNA CTD PMID:27188386 trimellitic anhydride increases expression ISO RGD:1320528 6480464 trimellitic anhydride results in increased expression of BCL11A mRNA CTD PMID:19042947 tunicamycin increases expression ISO RGD:1320528 6480464 Tunicamycin results in increased expression of BCL11A mRNA CTD PMID:17127020 valproic acid decreases expression ISO RGD:1320527 6480464 Valproic Acid results in decreased expression of BCL11A mRNA CTD PMID:24935251 valproic acid increases expression ISO RGD:1320527 6480464 Valproic Acid results in increased expression of BCL11A mRNA CTD PMID:19101580 more ... valproic acid multiple interactions ISO RGD:1320527 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BCL11A mRNA CTD PMID:27188386 vitamin E decreases expression ISO RGD:1320527 6480464 Vitamin E results in decreased expression of BCL11A mRNA CTD PMID:19244175 vorinostat multiple interactions ISO RGD:1320527 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BCL11A mRNA CTD PMID:27188386 vorinostat increases expression ISO RGD:1320527 6480464 vorinostat results in increased expression of BCL11A mRNA CTD PMID:26272509
Biological Process B cell differentiation ISO RGD:1320528 1624291 MGI:MGI:2663941 (MGI:MGI:2662805 , PMID:12717432) RGD MGI:MGI:2662805 , PMID:12717432 cellular response to L-glutamate IEP 11100020 RGD multicellular organism development IBA MGI:MGI:1929913 , PANTHER:PTN001905569 13792537 PMID:21873635 GO_Central negative regulation of branching morphogenesis of a nerve IMP 11100018 RGD negative regulation of collateral sprouting ISO RGD:1320527 1624291 (PMID:19616629) RGD PMID:19616629 negative regulation of dendrite development IMP 11100018 RGD negative regulation of dendrite development ISO RGD:1320527 1624291 (PMID:19616629) RGD PMID:19616629 negative regulation of dendrite extension IMP 11100018 RGD negative regulation of gene expression ISO RGD:1320528 1624291 MGI:MGI:4358088 (MGI:MGI:4355757 , PMID:19657335) RGD MGI:MGI:4355757 , PMID:19657335 negative regulation of neuron projection development ISO RGD:1320527 1624291 (PMID:19616629) RGD PMID:19616629 negative regulation of neuron remodeling IMP 11100018 RGD negative regulation of transcription by RNA polymerase II ISO RGD:1320527 1624291 (PMID:19153051) RGD PMID:19153051 negative regulation of transcription by RNA polymerase II IBA PANTHER:PTN000579359 , UniProtKB:Q9H165 13792537 PMID:21873635 GO_Central negative regulation of transcription by RNA polymerase II IBA MGI:MGI:1926956 more ... 13792537 PMID:21873635 GO_Central positive regulation of collateral sprouting ISO RGD:1320527 1624291 (PMID:19616629) RGD PMID:19616629 positive regulation of gene expression IMP 11100018 Dcc, Map1b RGD positive regulation of neuron projection development ISO RGD:1320527 1624291 (PMID:19616629) RGD PMID:19616629 protein sumoylation ISO RGD:1320528 1624291 (MGI:MGI:3820475, PMID:18681895) RGD MGI:MGI:3820475 , PMID:18681895 regulation of dendrite development ISO RGD:1320527 1624291 (PMID:19616629) RGD PMID:19616629 regulation of transcription, DNA-templated IBA FB:FBgn0011236 , PANTHER:PTN001905569 13792537 PMID:21873635 GO_Central T cell differentiation ISO RGD:1320528 1624291 MGI:MGI:2663941 (MGI:MGI:2662805 , PMID:12717432) RGD MGI:MGI:2662805 , PMID:12717432 Cellular Component cytoplasm IDA 11100019 RGD nuclear body ISO RGD:1320528 1624291 (MGI:MGI:3820475, PMID:18681895) RGD MGI:MGI:3820475 , PMID:18681895 nucleoplasm ISO RGD:1320527 1624291 RGD GO_REF:0000052 nucleoplasm IEA UniProtKB:D6W5D9 , ensembl:ENSP000004961681600115 GO_REF:0000107 Ensembl GO_REF:0000107 nucleoplasm IEA UniProtKB:Q9H165 , ensembl:ENSP000004961681600115 GO_REF:0000107 Ensembl GO_REF:0000107 nucleus ISO RGD:1320528 1624291 (MGI:MGI:1355195, PMID:10744719) RGD MGI:MGI:1355195 , PMID:10744719 nucleus IBA FB:FBgn0011236 more ... 13792537 PMID:21873635 GO_Central nucleus ISO RGD:1320527 1624291 (PMID:19616629) RGD PMID:19616629 nucleus IDA 11100016 RGD postsynaptic density IDA 11100019 RGD Molecular Function DNA-binding transcription factor activity IBA FB:FBgn0011236 , PANTHER:PTN001905569 13792537 PMID:21873635 GO_Central DNA-binding transcription repressor activity, RNA polymerase II-specific ISO RGD:1320527 1624291 (PMID:19153051) RGD PMID:19153051 DNA-binding transcription repressor activity, RNA polymerase II-specific IEA UniProtKB:Q9H165 , ensembl:ENSP000004961681600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein binding ISO RGD:1320527 1624291 UniProtKB:O43167 more ... RGD PMID:25416956 protein binding ISO RGD:1320528 1624291 UniProtKB:O54714 (MGI:MGI:3820475 , PMID:18681895) RGD MGI:MGI:3820475 , PMID:18681895 protein heterodimerization activity ISO RGD:1320527 1624291 UniProtKB:Q9H165-2 , UniProtKB:Q9H165-3 (PMID:19616629) RGD PMID:19616629 protein kinase binding IPI RGD:62004 11100016 RGD RNA polymerase II cis-regulatory region sequence-specific DNA binding ISO RGD:1320527 1624291 (PMID:19153051) RGD PMID:19153051 RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA UniProtKB:Q9H165 , ensembl:ENSP000004961681600115 GO_REF:0000107 Ensembl GO_REF:0000107 sequence-specific DNA binding IBA MGI:MGI:1929913 , PANTHER:PTN001905569 13792537 PMID:21873635 GO_Central transcription corepressor activity ISO RGD:1320528 1624291 (MGI:MGI:1355195, PMID:10744719) RGD MGI:MGI:1355195 , PMID:10744719
Gene-Chemical Interaction Annotations
