(+)-alpha-tocopherol increases expression ISO RGD:1352787 6480464 alpha-Tocopherol analog results in increased expression of XBP1 mRNA CTD PMID:20686688 (+)-catechin multiple interactions ISO RGD:1352787 6480464 [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of XBP1 mRNA CTD PMID:24763279 (-)-anisomycin decreases splicing ISO RGD:1332312 6480464 Anisomycin results in decreased splicing of XBP1 mRNA CTD PMID:25324550 (R)-noradrenaline affects localization EXP 6480464 Norepinephrine affects the localization of XBP1 protein CTD PMID:16338971 (S)-nicotine multiple interactions EXP 6480464 Nicotine inhibits the reaction [Tunicamycin results in increased splicing of XBP1 mRNA] CTD PMID:18477628 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases response to substance ISO RGD:1352787 6480464 XBP1 protein results in decreased susceptibility to 1-Methyl-4-phenyl-1 more ... CTD PMID:19135031 17alpha-ethynylestradiol multiple interactions ISO RGD:1332312 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of XBP1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression ISO RGD:1332312 6480464 Ethinyl Estradiol results in increased expression of XBP1 mRNA CTD PMID:17555576 , PMID:17942748 17beta-estradiol increases expression ISO RGD:1352787 6480464 Estradiol results in increased expression of XBP1 mRNA CTD PMID:14605097 more ... 17beta-estradiol multiple interactions ISO RGD:1352787 6480464 (+)-JQ1 compound inhibits the reaction [Estradiol promotes the reaction [ESR1 protein binds to XBP1 promoter]] more ... CTD PMID:20068169 , PMID:25721606 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:1352787 6480464 2 more ... CTD PMID:19095052 , PMID:22543052 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO RGD:1332312 6480464 2 more ... CTD PMID:30294300 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions ISO RGD:1352787 6480464 ERN1 protein affects the reaction [2 more ... CTD PMID:22543052 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1332312 6480464 Tetrachlorodibenzodioxin affects the expression of XBP1 mRNA CTD PMID:24058054 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1332312 6480464 Tetrachlorodibenzodioxin results in increased expression of XBP1 mRNA CTD PMID:17942748 , PMID:20819909 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1332312 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of XBP1 mRNA more ... CTD PMID:14600275 more ... 2,4-dichlorophenol increases splicing ISO RGD:1332312 6480464 2, 4-dichlorophenol results in increased splicing of XBP1 mRNA CTD PMID:25160872 , PMID:27853103 2,4-dichlorophenol increases splicing ISO RGD:1352787 6480464 2, 4-dichlorophenol results in increased splicing of XBP1 mRNA CTD PMID:27853103 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO RGD:1352787 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA], tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA] CTD PMID:20165829 2-amino-2-deoxy-D-glucopyranose increases splicing ISO RGD:1332312 6480464 Glucosamine results in increased splicing of XBP1 mRNA CTD PMID:30602124 2-amino-2-deoxy-D-glucopyranose increases expression ISO RGD:1332312 6480464 Glucosamine results in increased expression of XBP1 protein alternative form CTD PMID:30602124 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO RGD:1332312 6480464 4-methylumbelliferone 8-carbaldehyde affects the reaction [Glucosamine results in increased expression of XBP1 protein alternative form] more ... CTD PMID:30602124 2-amino-2-deoxy-D-glucopyranose multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA], tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA] CTD PMID:20165829 2-amino-2-deoxy-D-glucopyranose increases expression EXP 6480464 Glucosamine results in increased expression of XBP1 mRNA CTD PMID:20165829 2-amino-2-deoxy-D-glucopyranose increases expression ISO RGD:1352787 6480464 Glucosamine results in increased expression of XBP1 mRNA CTD PMID:20165829 2-amino-2-deoxy-D-glucopyranose decreases splicing ISO RGD:1352787 6480464 Glucosamine results in decreased splicing of XBP1 mRNA CTD PMID:19383982 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of XBP1 mRNA CTD PMID:28522335 4,4'-diaminodiphenylmethane decreases expression ISO RGD:1332312 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of XBP1 mRNA CTD PMID:18648102 4-aminophenol multiple interactions EXP 6480464 PD 150606 inhibits the reaction [4-aminophenol results in increased expression of XBP1 protein] CTD PMID:17567592 4-aminophenol increases expression EXP 6480464 4-aminophenol results in increased expression of XBP1 mRNA, 4-aminophenol results in increased expression of XBP1 protein CTD PMID:17567590 , PMID:17567592 4-hydroxynon-2-enal increases splicing EXP 6480464 4-hydroxy-2-nonenal results in increased splicing of XBP1 mRNA CTD PMID:24291486 4-hydroxyphenyl retinamide increases splicing ISO RGD:1352787 6480464 Fenretinide results in increased splicing of XBP1 mRNA CTD PMID:17353921 4-hydroxyphenyl retinamide decreases expression ISO RGD:1332312 6480464 Fenretinide results in decreased expression of XBP1 mRNA CTD PMID:28973697 4-nitrophenol increases expression ISO RGD:1332312 6480464 4-nitrophenol results in increased expression of XBP1 mRNA CTD PMID:23997041 4-nitrophenol multiple interactions ISO RGD:1332312 6480464 Quercetin inhibits the reaction [4-nitrophenol results in increased expression of XBP1 mRNA] CTD PMID:23997041 4-phenylbutyric acid multiple interactions ISO RGD:1332312 6480464 4-phenylbutyric acid affects the reaction [LEPR gene mutant form affects the splicing of XBP1 mRNA] more ... CTD PMID:23274897 more ... 4-phenylbutyric acid decreases expression ISO RGD:1352787 6480464 4-phenylbutyric acid results in decreased expression of XBP1 protein alternative form CTD PMID:29444456 , PMID:30796460 4-phenylbutyric acid multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA] CTD PMID:20165829 4-phenylbutyric acid multiple interactions ISO RGD:1352787 6480464 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of XBP1 protein alternative form] more ... CTD PMID:20165829 more ... 5-fluorouracil increases expression ISO RGD:1352787 6480464 Fluorouracil results in increased expression of XBP1 mRNA CTD PMID:15205334 8-Br-cAMP increases expression ISO RGD:1352787 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of XBP1 mRNA CTD PMID:22079614 acrolein affects splicing ISO RGD:1352787 6480464 Acrolein affects the splicing of XBP1 mRNA CTD PMID:18951912 afimoxifene multiple interactions ISO RGD:1352787 6480464 afimoxifene inhibits the reaction [Estrogens results in increased expression of XBP1 mRNA] CTD PMID:21233418 aflatoxin B1 decreases expression ISO RGD:1352787 6480464 Aflatoxin B1 results in decreased expression of XBP1 mRNA CTD PMID:27153756 aldehydo-D-glucosamine multiple interactions ISO RGD:1352787 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA], tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA] CTD PMID:20165829 aldehydo-D-glucosamine increases splicing ISO RGD:1332312 6480464 Glucosamine results in increased splicing of XBP1 mRNA CTD PMID:30602124 aldehydo-D-glucosamine multiple interactions ISO RGD:1332312 6480464 4-methylumbelliferone 8-carbaldehyde affects the reaction [Glucosamine results in increased expression of XBP1 protein alternative form] more ... CTD PMID:30602124 aldehydo-D-glucosamine increases expression ISO RGD:1332312 6480464 Glucosamine results in increased expression of XBP1 protein alternative form CTD PMID:30602124 aldehydo-D-glucosamine multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA], tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA] CTD PMID:20165829 aldehydo-D-glucosamine increases expression EXP 6480464 Glucosamine results in increased expression of XBP1 mRNA CTD PMID:20165829 aldehydo-D-glucosamine increases expression ISO RGD:1352787 6480464 Glucosamine results in increased expression of XBP1 mRNA CTD PMID:20165829 aldehydo-D-glucosamine decreases splicing ISO RGD:1352787 6480464 Glucosamine results in decreased splicing of XBP1 mRNA CTD PMID:19383982 aldehydo-D-glucose increases expression EXP 6480464 Glucose deficiency results in increased expression of XBP1 protein CTD PMID:21337367 aldehydo-D-glucose multiple interactions ISO RGD:1352787 6480464 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased splicing of XBP1 mRNA], XBP1 mRNA alternative form promotes the reaction [4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased expression of HSPA5 protein]] CTD PMID:31022492 aldehydo-D-glucose increases splicing ISO RGD:1352787 6480464 Glucose deficiency results in increased splicing of XBP1 mRNA CTD PMID:31022492 aldehydo-D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of XBP1 mRNA CTD PMID:24349266 aldehydo-D-glucose decreases expression ISO RGD:1332312 6480464 Glucose results in decreased expression of XBP1 mRNA CTD PMID:17178593 all-trans-retinoic acid multiple interactions ISO RGD:1352787 6480464 MGAT5 protein inhibits the reaction [Tretinoin results in increased expression of XBP1 protein alternative form] CTD PMID:17031849 all-trans-retinoic acid increases expression ISO RGD:1332312 6480464 Tretinoin results in increased expression of XBP1 mRNA, Tretinoin results in increased expression of XBP1 protein CTD PMID:22498432 all-trans-retinoic acid increases expression ISO RGD:1352787 6480464 Tretinoin results in increased expression of XBP1 mRNA alternative form, Tretinoin results in increased expression of XBP1 protein alternative form CTD PMID:17031849 , PMID:19960509 Aloe emodin increases splicing ISO RGD:1352787 6480464 aloe emodin results in increased splicing of XBP1 mRNA CTD PMID:22210228 AM-251 increases expression ISO RGD:1352787 6480464 AM 251 results in increased expression of XBP1 mRNA CTD PMID:16500647 amiloride multiple interactions ISO RGD:1332312 6480464 Amiloride inhibits the reaction [Tunicamycin results in increased splicing of XBP1 mRNA] CTD PMID:20015086 amiodarone increases expression ISO RGD:1352787 6480464 Amiodarone results in increased expression of XBP1 mRNA CTD PMID:19774075 amiodarone multiple interactions ISO RGD:1332312 6480464 1-(3 more ... CTD PMID:28962527 amiodarone affects localization ISO RGD:1332312 6480464 Amiodarone affects the localization of XBP1 protein CTD PMID:28962527 amiodarone increases splicing ISO RGD:1332312 6480464 Amiodarone results in increased splicing of XBP1 mRNA CTD PMID:28962527 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of XBP1 mRNA CTD PMID:16483693 amosite asbestos increases expression ISO RGD:1352787 6480464 Asbestos, Amosite results in increased expression of XBP1 protein alternative form CTD PMID:23885834 amosite asbestos multiple interactions ISO RGD:1352787 6480464 Asbestos, Amosite results in increased expression of and affects the splicing of XBP1 mRNA, BCL2L1 protein inhibits the reaction [Asbestos, Amosite results in increased expression of XBP1 protein alternative form] CTD PMID:23885834 antimycin A increases expression EXP 6480464 Antimycin A results in increased expression of XBP1 protein CTD PMID:21337367 antirheumatic drug decreases expression ISO RGD:1352787 6480464 Antirheumatic Agents results in decreased expression of XBP1 mRNA CTD PMID:24449571 aristolochic acid increases splicing ISO RGD:1352787 6480464 aristolochic acid I results in increased splicing of XBP1 mRNA CTD PMID:22445861 arsenite(3-) multiple interactions ISO RGD:1352787 6480464 Sirolimus inhibits the reaction [arsenite results in increased splicing of XBP1 mRNA], SLC38A2 mutant form inhibits the reaction [arsenite results in increased splicing of XBP1 mRNA] CTD PMID:22215663 arsenite(3-) increases splicing ISO RGD:1352787 6480464 arsenite results in increased splicing of XBP1 mRNA CTD PMID:22215663 arsenous acid increases expression ISO RGD:1332312 6480464 Arsenic Trioxide results in increased expression of XBP1 mRNA, Arsenic Trioxide results in increased expression of XBP1 protein CTD PMID:24157283 arsenous acid increases expression ISO RGD:1352787 6480464 Arsenic Trioxide results in increased expression of XBP1 mRNA more ... CTD PMID:22959511 , PMID:23883479 arsenous acid increases splicing ISO RGD:1352787 6480464 Arsenic Trioxide results in increased splicing of XBP1 mRNA CTD PMID:22922937 arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of XBP1 protein CTD PMID:21145380 arsenous acid multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of XBP1 protein] CTD PMID:21145380 arsenous acid multiple interactions ISO RGD:1352787 6480464 Acetylcysteine inhibits the reaction [XBP1 protein inhibits the reaction [Arsenic Trioxide results in increased abundance of Reactive Oxygen Species]] more ... CTD PMID:21138464 , PMID:22922937 atrazine increases expression ISO RGD:1352787 6480464 Atrazine results in increased expression of XBP1 mRNA CTD PMID:22378314 benzalkonium chloride decreases expression ISO RGD:1352787 6480464 Benzalkonium Compounds results in decreased expression of XBP1 mRNA alternative form CTD PMID:28236482 benzene increases expression ISO RGD:1352787 6480464 Benzene results in increased expression of XBP1 mRNA CTD PMID:20359517 benzo[a]pyrene decreases expression ISO RGD:1352787 6480464 Benzo(a)pyrene results in decreased expression of XBP1 mRNA CTD PMID:21632981 , PMID:32234424 benzo[a]pyrene multiple interactions ISO RGD:1332312 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of XBP1 mRNA CTD PMID:27858113 benzo[a]pyrene diol epoxide I increases expression ISO RGD:1352787 6480464 7 more ... CTD PMID:19150397 benzo[b]fluoranthene increases expression ISO RGD:1332312 6480464 benzo(b)fluoranthene results in increased expression of XBP1 mRNA CTD PMID:26377693 benzo[b]fluoranthene multiple interactions ISO RGD:1332312 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of XBP1 mRNA CTD PMID:27858113 benzoates increases expression ISO RGD:1352787 6480464 Benzoates analog results in increased expression of XBP1 mRNA CTD PMID:29472718 beta-D-glucosamine multiple interactions ISO RGD:1352787 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA], tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA] CTD PMID:20165829 beta-D-glucosamine increases splicing ISO RGD:1332312 6480464 Glucosamine results in increased splicing of XBP1 mRNA CTD PMID:30602124 beta-D-glucosamine multiple interactions ISO RGD:1332312 6480464 4-methylumbelliferone 8-carbaldehyde affects the reaction [Glucosamine results in increased expression of XBP1 protein alternative form] more ... CTD PMID:30602124 beta-D-glucosamine increases expression ISO RGD:1332312 6480464 Glucosamine results in increased expression of XBP1 protein alternative form CTD PMID:30602124 beta-D-glucosamine multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA], tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA] CTD PMID:20165829 beta-D-glucosamine increases expression EXP 6480464 Glucosamine results in increased expression of XBP1 mRNA CTD PMID:20165829 beta-D-glucosamine increases expression ISO RGD:1352787 6480464 Glucosamine results in increased expression of XBP1 mRNA CTD PMID:20165829 beta-D-glucosamine decreases splicing ISO RGD:1352787 6480464 Glucosamine results in decreased splicing of XBP1 mRNA CTD PMID:19383982 beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of XBP1 mRNA CTD PMID:18164116 bexarotene decreases expression ISO RGD:1352787 6480464 bexarotene results in decreased expression of XBP1 mRNA CTD PMID:17178900 bilirubin IXalpha increases expression ISO RGD:1352787 6480464 Bilirubin results in increased expression of XBP1 mRNA CTD PMID:27578021 bilirubin IXalpha multiple interactions ISO RGD:1332312 6480464 4-phenylbutyric acid inhibits the reaction [Bilirubin results in increased expression of XBP1 mRNA] CTD PMID:27578021 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of XBP1 mRNA CTD PMID:25181051 bisphenol A affects methylation ISO RGD:1332312 6480464 bisphenol A affects the methylation of XBP1 promoter CTD PMID:27334623 boric acid increases expression ISO RGD:1352787 6480464 boric acid results in increased expression of XBP1 mRNA CTD PMID:27587023 bortezomib multiple interactions ISO RGD:1352787 6480464 Bortezomib inhibits the reaction [Brefeldin A results in increased activity of XBP1 protein] CTD PMID:18723477 bortezomib increases activity ISO RGD:1352787 6480464 Bortezomib results in increased activity of XBP1 protein CTD PMID:18723477 brefeldin A multiple interactions ISO RGD:1352787 6480464 bortezomib inhibits the reaction [Brefeldin A results in increased activity of XBP1 protein] CTD PMID:18723477 brefeldin A increases expression ISO RGD:1352787 6480464 Brefeldin A results in increased expression of XBP1 protein CTD PMID:27358234 brefeldin A increases activity ISO RGD:1352787 6480464 Brefeldin A results in increased activity of XBP1 protein CTD PMID:18723477 bupropion decreases splicing ISO RGD:1352787 6480464 Bupropion results in decreased splicing of XBP1 mRNA CTD PMID:21354251 butan-1-ol multiple interactions ISO RGD:1352787 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of XBP1 mRNA CTD PMID:29432896 butanal decreases expression ISO RGD:1352787 6480464 butyraldehyde results in decreased expression of XBP1 mRNA CTD PMID:26079696 cadmium atom increases activity ISO RGD:1332312 6480464 Cadmium results in increased activity of XBP1 protein CTD PMID:20600546 cadmium dichloride increases expression ISO RGD:1332312 6480464 Cadmium Chloride results in increased expression of XBP1 mRNA alternative form CTD PMID:21908765 cadmium dichloride increases acetylation ISO RGD:1352787 6480464 Cadmium Chloride results in increased acetylation of XBP1 protein alternative form CTD PMID:30796460 cadmium dichloride multiple interactions EXP 6480464 Resveratrol inhibits the reaction [Cadmium Chloride results in increased expression of XBP1 mRNA], Resveratrol inhibits the reaction [Cadmium Chloride results in increased expression of XBP1 protein] CTD PMID:31433112 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of XBP1 mRNA, Cadmium Chloride results in increased expression of XBP1 protein CTD PMID:31433112 cadmium dichloride multiple interactions ISO RGD:1352787 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [Cadmium Chloride results in increased expression of XBP1 protein alternative form] more ... CTD PMID:29444456 , PMID:30796460 cadmium dichloride decreases expression ISO RGD:1352787 6480464 Cadmium Chloride results in decreased expression of XBP1 mRNA CTD PMID:25596134 cadmium dichloride affects activity ISO RGD:1352787 6480464 Cadmium Chloride affects the activity of XBP1 protein CTD PMID:25596134 cadmium dichloride increases expression ISO RGD:1352787 6480464 Cadmium Chloride results in increased expression of XBP1 mRNA alternative form, Cadmium Chloride results in increased expression of XBP1 protein alternative form CTD PMID:19426795 more ... cadmium dichloride increases splicing ISO RGD:1332312 6480464 Cadmium Chloride results in increased splicing of XBP1 mRNA CTD PMID:17588656 cadmium dichloride multiple interactions ISO RGD:1332312 6480464 Phenylbutyrates inhibits the reaction [Cadmium Chloride results in increased expression of XBP1 mRNA alternative form] CTD PMID:21908765 Calcimycin increases splicing ISO RGD:1352787 6480464 Calcimycin results in increased splicing of XBP1 mRNA CTD PMID:19428936 Calcimycin multiple interactions ISO RGD:1352787 6480464 Quercetin inhibits the reaction [Calcimycin results in increased splicing of XBP1 mRNA] CTD PMID:19428936 carbamazepine affects expression ISO RGD:1352787 6480464 Carbamazepine affects the expression of XBP1 mRNA CTD PMID:25979313 carbaryl increases expression ISO RGD:1352787 6480464 Carbaryl results in increased expression of XBP1 mRNA CTD PMID:27829164 carbon nanotube increases expression ISO RGD:1352787 6480464 Nanotubes, Carbon results in increased expression of XBP1 mRNA, Nanotubes, Carbon results in increased expression of XBP1 mRNA alternative form CTD PMID:25511174 more ... carbon nanotube decreases splicing ISO RGD:1352787 6480464 Nanotubes, Carbon analog results in decreased splicing of XBP1 mRNA CTD PMID:30138652 carbon nanotube increases expression ISO RGD:1332312 6480464 Nanotubes, Carbon analog results in increased expression of XBP1 mRNA, Nanotubes, Carbon results in increased expression of XBP1 mRNA CTD PMID:25554681 , PMID:25620056 casticin increases expression ISO RGD:1352787 6480464 casticin results in increased expression of XBP1 mRNA CTD PMID:27862857 cerulenin multiple interactions ISO RGD:1352787 6480464 Cerulenin affects the reaction [ERN1 protein affects the splicing of XBP1 mRNA] CTD PMID:17283163 ceruletide increases expression EXP 6480464 Ceruletide results in increased expression of XBP1 mRNA alternative form, Ceruletide results in increased expression of XBP1 protein alternative form CTD PMID:26873426 ceruletide multiple interactions EXP 6480464 Dietary Fats promotes the reaction [Ceruletide results in increased expression of XBP1 mRNA alternative form] more ... CTD PMID:26873426 chloroacetaldehyde affects expression ISO RGD:1352787 6480464 chloroacetaldehyde affects the expression of XBP1 mRNA CTD PMID:25596134 chloroacetaldehyde affects activity ISO RGD:1352787 6480464 chloroacetaldehyde affects the activity of XBP1 protein CTD PMID:25596134 chloroacetic acid multiple interactions ISO RGD:1332312 6480464 Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of XBP1 protein alternative form] CTD PMID:25451595 chloroacetic acid increases expression ISO RGD:1332312 6480464 chloroacetic acid results in increased expression of XBP1 mRNA alternative form, chloroacetic acid results in increased expression of XBP1 protein alternative form CTD PMID:25451595 chloropicrin affects expression ISO RGD:1352787 6480464 chloropicrin affects the expression of XBP1 mRNA CTD PMID:26352163 chlorpromazine affects activity EXP 6480464 Chlorpromazine affects the activity of XBP1 protein CTD PMID:25596134 chlorpromazine decreases expression EXP 6480464 Chlorpromazine results in decreased expression of XBP1 mRNA CTD PMID:25596134 chlorpyrifos increases splicing ISO RGD:1352787 6480464 Chlorpyrifos results in increased splicing of XBP1 mRNA CTD PMID:27993609 choline multiple interactions ISO RGD:1332312 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of XBP1 gene CTD PMID:20938992 chrysene multiple interactions ISO RGD:1332312 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of XBP1 mRNA CTD PMID:27858113 cidofovir anhydrous affects activity ISO RGD:1352787 6480464 Cidofovir affects the activity of XBP1 protein CTD PMID:25596134 cidofovir anhydrous increases expression ISO RGD:1352787 6480464 Cidofovir results in increased expression of XBP1 mRNA CTD PMID:25596134 cisplatin decreases expression ISO RGD:1332312 6480464 Cisplatin results in decreased expression of XBP1 mRNA CTD PMID:21151649 cisplatin multiple interactions ISO RGD:1352787 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of XBP1 mRNA CTD PMID:27392435 cisplatin affects activity ISO RGD:1352787 6480464 Cisplatin affects the activity of XBP1 protein CTD PMID:25596134 cisplatin decreases expression ISO RGD:1352787 6480464 Cisplatin results in decreased expression of XBP1 mRNA CTD PMID:25596134 cisplatin increases expression ISO RGD:1352787 6480464 Cisplatin results in increased expression of XBP1 mRNA CTD PMID:19561079 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of XBP1 protein CTD PMID:17567590 clodronic acid affects activity ISO RGD:1352787 6480464 Clodronic Acid affects the activity of XBP1 protein CTD PMID:25596134 clodronic acid decreases expression ISO RGD:1352787 6480464 Clodronic Acid results in decreased expression of XBP1 mRNA CTD PMID:25596134 clofibrate multiple interactions ISO RGD:1332312 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of XBP1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of XBP1 mRNA] CTD PMID:17585979 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of XBP1 protein CTD PMID:21337367 cobalt dichloride decreases expression ISO RGD:1352787 6480464 cobaltous chloride results in decreased expression of XBP1 mRNA CTD PMID:19320972 cocaine increases expression EXP 6480464 Cocaine results in increased expression of XBP1 mRNA CTD PMID:23644055 copper atom multiple interactions ISO RGD:1352787 6480464 [NSC 689534 binds to Copper] which results in increased expression of XBP1 mRNA CTD PMID:20971185 copper(0) multiple interactions ISO RGD:1352787 6480464 [NSC 689534 binds to Copper] which results in increased expression of XBP1 mRNA CTD PMID:20971185 copper(II) sulfate decreases expression ISO RGD:1352787 6480464 Copper Sulfate results in decreased expression of XBP1 mRNA CTD PMID:19549813 curcumin increases expression ISO RGD:1352787 6480464 Curcumin results in increased expression of XBP1 mRNA CTD PMID:29723631 cyclosporin A increases expression ISO RGD:1332312 6480464 Cyclosporine results in increased expression of XBP1 mRNA, Cyclosporine results in increased expression of XBP1 protein modified form CTD PMID:23958496 , PMID:25270620 cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of XBP1 mRNA CTD PMID:25596134 cyclosporin A affects activity EXP 6480464 Cyclosporine affects the activity of XBP1 protein CTD PMID:25596134 cyclosporin A increases expression ISO RGD:1352787 6480464 Cyclosporine results in increased expression of XBP1 mRNA CTD PMID:25596134 cyclosporin A affects activity ISO RGD:1352787 6480464 Cyclosporine affects the activity of XBP1 protein CTD PMID:25596134 cyclosporin A multiple interactions ISO RGD:1332312 6480464 Cyclosporine results in increased expression of and affects the localization of XBP1 protein modified form CTD PMID:23958496 D-glucose decreases expression ISO RGD:1332312 6480464 Glucose results in decreased expression of XBP1 mRNA CTD PMID:17178593 D-glucose increases splicing ISO RGD:1352787 6480464 Glucose deficiency results in increased splicing of XBP1 mRNA CTD PMID:31022492 D-glucose multiple interactions ISO RGD:1352787 6480464 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased splicing of XBP1 mRNA], XBP1 mRNA alternative form promotes the reaction [4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased expression of HSPA5 protein]] CTD PMID:31022492 D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of XBP1 mRNA CTD PMID:24349266 D-glucose increases expression EXP 6480464 Glucose deficiency results in increased expression of XBP1 protein CTD PMID:21337367 D-penicillamine increases splicing ISO RGD:1352787 6480464 Penicillamine results in increased splicing of XBP1 mRNA CTD PMID:19722195 deoxynivalenol increases splicing ISO RGD:1332312 6480464 deoxynivalenol results in increased splicing of XBP1 mRNA CTD PMID:19336499 deoxynivalenol increases expression ISO RGD:1332312 6480464 deoxynivalenol results in increased expression of XBP1 protein CTD PMID:19336499 desferrioxamine B multiple interactions ISO RGD:1352787 6480464 Deferoxamine promotes the reaction [Palmitic Acid results in increased expression of XBP1 protein] CTD PMID:32283200 diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of XBP1 protein CTD PMID:21145380 diarsenic trioxide multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of XBP1 protein] CTD PMID:21145380 diarsenic trioxide increases splicing ISO RGD:1352787 6480464 Arsenic Trioxide results in increased splicing of XBP1 mRNA CTD PMID:22922937 diarsenic trioxide increases expression ISO RGD:1332312 6480464 Arsenic Trioxide results in increased expression of XBP1 mRNA, Arsenic Trioxide results in increased expression of XBP1 protein CTD PMID:24157283 diarsenic trioxide multiple interactions ISO RGD:1352787 6480464 Acetylcysteine inhibits the reaction [XBP1 protein inhibits the reaction [Arsenic Trioxide results in increased abundance of Reactive Oxygen Species]] more ... CTD PMID:21138464 , PMID:22922937 diarsenic trioxide increases expression ISO RGD:1352787 6480464 Arsenic Trioxide results in increased expression of XBP1 mRNA more ... CTD PMID:22959511 , PMID:23883479 dibenz[a,h]anthracene increases expression ISO RGD:1332312 6480464 1 more ... CTD PMID:26377693 dibutyl phthalate increases expression ISO RGD:1332312 6480464 Dibutyl Phthalate results in increased expression of XBP1 mRNA CTD PMID:21266533 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of XBP1 mRNA CTD PMID:21266533 dichloromethane increases expression ISO RGD:1352787 6480464 Methylene Chloride results in increased expression of XBP1 mRNA CTD PMID:20359517 diclofenac increases expression ISO RGD:1332312 6480464 Diclofenac results in increased expression of XBP1 mRNA CTD PMID:26934552 dimethylarsinic acid increases expression ISO RGD:1352787 6480464 Cacodylic Acid results in increased expression of XBP1 mRNA, Cacodylic Acid results in increased expression of XBP1 mRNA alternative form CTD PMID:23221991 dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of XBP1 protein CTD PMID:21337367 dioxygen decreases expression ISO RGD:1352787 6480464 Oxygen deficiency results in decreased expression of XBP1 mRNA CTD PMID:25596134 dioxygen affects activity ISO RGD:1352787 6480464 Oxygen deficiency affects the activity of XBP1 protein CTD PMID:25596134 disodium selenite increases expression ISO RGD:1352787 6480464 Sodium Selenite results in increased expression of XBP1 mRNA CTD PMID:18175754 diuron decreases expression EXP 6480464 Diuron results in decreased expression of XBP1 mRNA CTD PMID:21551480 dorsomorphin multiple interactions ISO RGD:1352787 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of XBP1 mRNA CTD PMID:27188386 doxorubicin increases expression ISO RGD:1352787 6480464 Doxorubicin results in increased expression of XBP1 mRNA CTD PMID:15205334 ebselen increases phosphorylation EXP 6480464 ebselen results in increased phosphorylation of XBP1 protein CTD PMID:27282967 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of XBP1 mRNA CTD PMID:29391264 entinostat increases expression ISO RGD:1352787 6480464 entinostat results in increased expression of XBP1 mRNA CTD PMID:26272509 entinostat multiple interactions ISO RGD:1352787 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of XBP1 mRNA CTD PMID:27188386 erlotinib hydrochloride increases expression EXP 6480464 Erlotinib Hydrochloride results in increased expression of XBP1 protein modified form CTD PMID:24768708 ethanol decreases splicing ISO RGD:1332312 6480464 Ethanol results in decreased splicing of XBP1 mRNA CTD PMID:28119953 ethanol increases expression ISO RGD:1332312 6480464 Ethanol results in increased expression of XBP1 protein CTD PMID:29044621 ethylbenzene increases expression ISO RGD:1352787 6480464 ethylbenzene results in increased expression of XBP1 mRNA CTD PMID:20359517 fenofibrate decreases expression EXP 6480464 Fenofibrate results in decreased expression of XBP1 mRNA CTD PMID:25596134 fenofibrate affects activity ISO RGD:1352787 6480464 Fenofibrate affects the activity of XBP1 protein CTD PMID:25596134 fenofibrate affects activity EXP 6480464 Fenofibrate affects the activity of XBP1 protein CTD PMID:25596134 ferric ammonium citrate multiple interactions ISO RGD:1352787 6480464 ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased expression of XBP1 protein] CTD PMID:32283200 flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of XBP1 mRNA CTD PMID:24136188 folic acid multiple interactions ISO RGD:1332312 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of XBP1 gene CTD PMID:20938992 fructose affects localization ISO RGD:1332312 6480464 Fructose affects the localization of XBP1 protein CTD PMID:22698815 furan increases methylation EXP 6480464 furan results in increased methylation of XBP1 gene CTD PMID:22079235 gadolinium trichloride increases splicing EXP 6480464 gadolinium chloride results in increased splicing of XBP1 mRNA CTD PMID:21198628 gemcitabine multiple interactions ISO RGD:1352787 6480464 gemcitabine promotes the reaction [1-(2 more ... CTD PMID:21525939 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of XBP1 mRNA, Gentamicins results in increased expression of XBP1 protein CTD PMID:17567590 geraniol increases expression ISO RGD:1352787 6480464 geraniol results in increased expression of XBP1 mRNA CTD PMID:27683099 glucose decreases expression ISO RGD:1332312 6480464 Glucose results in decreased expression of XBP1 mRNA CTD PMID:17178593 glucose increases splicing ISO RGD:1352787 6480464 Glucose deficiency results in increased splicing of XBP1 mRNA CTD PMID:31022492 glucose multiple interactions ISO RGD:1352787 6480464 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased splicing of XBP1 mRNA], XBP1 mRNA alternative form promotes the reaction [4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased expression of HSPA5 protein]] CTD PMID:31022492 glucose decreases expression EXP 6480464 Glucose results in decreased expression of XBP1 mRNA CTD PMID:24349266 glucose increases expression EXP 6480464 Glucose deficiency results in increased expression of XBP1 protein CTD PMID:21337367 glutathione multiple interactions ISO RGD:1352787 6480464 Glutathione inhibits the reaction [1 more ... CTD PMID:24515801 glycine multiple interactions ISO RGD:1352787 6480464 Glycine affects the reaction [Homocysteine results in increased splicing of XBP1 mRNA] CTD PMID:27064126 glycyrrhetinate multiple interactions ISO RGD:1352787 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [Cadmium Chloride results in increased expression of XBP1 protein alternative form] CTD PMID:29444456 glycyrrhetinic acid multiple interactions ISO RGD:1352787 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [Cadmium Chloride results in increased expression of XBP1 protein alternative form] CTD PMID:29444456 hexadecanoic acid multiple interactions EXP 6480464 [Palmitic Acid co-treated with Sincalide] results in increased expression of XBP1 mRNA alternative form more ... CTD PMID:26873426 hexadecanoic acid multiple interactions ISO RGD:1352787 6480464 Deferoxamine promotes the reaction [Palmitic Acid results in increased expression of XBP1 protein], ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased expression of XBP1 protein] CTD PMID:32283200 hexadecanoic acid increases expression ISO RGD:1352787 6480464 Palmitic Acid results in increased expression of XBP1 protein CTD PMID:32283200 hexadecanoic acid increases expression ISO RGD:1332312 6480464 Palmitic Acid results in increased expression of XBP1 mRNA alternative form CTD PMID:29414781 hexadecanoic acid multiple interactions ISO RGD:1332312 6480464 7 more ... CTD PMID:29414781 homocysteine multiple interactions ISO RGD:1352787 6480464 Glycine affects the reaction [Homocysteine results in increased splicing of XBP1 mRNA] CTD PMID:27064126 homocysteine decreases expression ISO RGD:1352787 6480464 Homocysteine results in decreased expression of XBP1 protein CTD PMID:22964297 homocysteine increases expression ISO RGD:1352787 6480464 Homocysteine results in increased expression of XBP1 mRNA alternative form CTD PMID:19960509 homocysteine increases splicing ISO RGD:1352787 6480464 Homocysteine results in increased splicing of XBP1 mRNA CTD PMID:27064126 hydrogen peroxide affects splicing ISO RGD:1352787 6480464 Hydrogen Peroxide affects the splicing of XBP1 mRNA CTD PMID:23885834 hydrogen peroxide multiple interactions ISO RGD:1352787 6480464 Acetylcysteine inhibits the reaction [XBP1 protein inhibits the reaction [Hydrogen Peroxide results in increased abundance of Reactive Oxygen Species]], XBP1 protein inhibits the reaction [Hydrogen Peroxide results in increased abundance of Reactive Oxygen Species] CTD PMID:21138464 hydrogen peroxide decreases response to substance ISO RGD:1352787 6480464 XBP1 protein results in decreased susceptibility to Hydrogen Peroxide CTD PMID:21138464 hydrogen peroxide increases expression ISO RGD:1352787 6480464 Hydrogen Peroxide results in increased expression of XBP1 protein alternative form CTD PMID:23885834 hydroxychloroquine multiple interactions ISO RGD:1352787 6480464 [Hydroxychloroquine co-treated with Methotrexate co-treated with Sulfasalazine] results in decreased expression of XBP1 mRNA CTD PMID:28863153 ibuprofen affects activity ISO RGD:1352787 6480464 Ibuprofen affects the activity of XBP1 protein CTD PMID:25596134 ifosfamide affects activity ISO RGD:1352787 6480464 Ifosfamide affects the activity of XBP1 protein CTD PMID:25596134 Indeno[1,2,3-cd]pyrene decreases expression ISO RGD:1352787 6480464 indeno(1 more ... CTD PMID:32251684 indometacin increases expression ISO RGD:1352787 6480464 Indomethacin results in increased expression of XBP1 mRNA CTD PMID:17401462 indoxyl sulfate increases splicing ISO RGD:1332312 6480464 Indican results in increased splicing of XBP1 mRNA CTD PMID:29380555 L-methionine multiple interactions ISO RGD:1332312 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of XBP1 gene CTD PMID:20938992 lactacystin decreases response to substance ISO RGD:1352787 6480464 XBP1 protein results in decreased susceptibility to lactacystin CTD PMID:19135031 lanthanum atom increases expression ISO RGD:1352787 6480464 Lanthanum results in increased expression of XBP1 mRNA alternative form CTD PMID:18773883 leflunomide increases expression ISO RGD:1352787 6480464 leflunomide results in increased expression of XBP1 mRNA, leflunomide results in increased expression of XBP1 protein alternative form CTD PMID:28988120 lipopolysaccharide multiple interactions ISO RGD:1332312 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Lipopolysaccharides results in increased expression of XBP1 mRNA] more ... CTD PMID:14600275 more ... lipopolysaccharide multiple interactions ISO RGD:1352787 6480464 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of XBP1 protein alternative form], [Estrogens, Conjugated (USP) co-treated with Lipopolysaccharides] results in increased expression of XBP1 mRNA CTD PMID:28245985 , PMID:31217279 lipopolysaccharide increases expression ISO RGD:1352787 6480464 Lipopolysaccharides results in increased expression of XBP1 protein alternative form CTD PMID:28245985 lipopolysaccharide increases splicing ISO RGD:1332312 6480464 Lipopolysaccharides results in increased splicing of XBP1 mRNA CTD PMID:18483191 lipopolysaccharide increases expression ISO RGD:1332312 6480464 Lipopolysaccharides results in increased expression of XBP1 mRNA, Lipopolysaccharides results in increased expression of XBP1 protein CTD PMID:14600275 more ... manganese(II) chloride increases splicing EXP 6480464 manganese chloride results in increased splicing of XBP1 mRNA CTD PMID:23948121 manganese(II) chloride multiple interactions EXP 6480464 manganese chloride results in increased expression of and results in increased splicing of XBP1 mRNA, SNCA protein promotes the reaction [manganese chloride results in increased expression of and results in increased splicing of XBP1 mRNA] CTD PMID:23934647 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [Methamphetamine results in increased expression of XBP1 mRNA alternative form], Melatonin inhibits the reaction [sodium arsenite results in increased expression of XBP1 protein] CTD PMID:17645694 , PMID:28070110 menadione affects expression ISO RGD:1352787 6480464 Vitamin K 3 affects the expression of XBP1 mRNA CTD PMID:20044591 metformin affects activity EXP 6480464 Metformin affects the activity of XBP1 protein CTD PMID:25596134 metformin multiple interactions ISO RGD:1352787 6480464 [Paclitaxel co-treated with Metformin] results in decreased expression of XBP1 mRNA CTD PMID:29309887 metformin affects expression EXP 6480464 Metformin affects the expression of XBP1 mRNA CTD PMID:25596134 methamphetamine increases expression ISO RGD:1332312 6480464 Methamphetamine results in increased expression of XBP1 protein CTD PMID:27323860 methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of XBP1 mRNA, Methamphetamine results in increased expression of XBP1 mRNA alternative form CTD PMID:19564919 , PMID:28070110 methamphetamine multiple interactions EXP 6480464 Melatonin inhibits the reaction [Methamphetamine results in increased expression of XBP1 mRNA alternative form] more ... CTD PMID:19564919 , PMID:28070110 methamphetamine increases expression ISO RGD:1352787 6480464 Methamphetamine results in increased expression of XBP1 mRNA, Methamphetamine results in increased expression of XBP1 protein CTD PMID:27323860 methamphetamine multiple interactions ISO RGD:1352787 6480464 ATF6 protein affects the reaction [Methamphetamine results in increased expression of XBP1 mRNA], ATF6 protein affects the reaction [Methamphetamine results in increased expression of XBP1 protein] CTD PMID:27323860 methotrexate multiple interactions ISO RGD:1352787 6480464 [Hydroxychloroquine co-treated with Methotrexate co-treated with Sulfasalazine] results in decreased expression of XBP1 mRNA CTD PMID:28863153 methylmercury chloride increases expression ISO RGD:1352787 6480464 methylmercuric chloride results in increased expression of XBP1 mRNA CTD PMID:23179753 more ... methylmercury chloride multiple interactions ISO RGD:1332312 6480464 Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of XBP1 protein alternative form] more ... CTD PMID:31330229 methylmercury chloride increases expression ISO RGD:1332312 6480464 methylmercuric chloride results in increased expression of XBP1 mRNA alternative form, methylmercuric chloride results in increased expression of XBP1 protein alternative form CTD PMID:31330229 methylseleninic acid increases splicing ISO RGD:1352787 6480464 methylselenic acid results in increased splicing of XBP1 mRNA CTD PMID:16205645 , PMID:28161410 mevastatin multiple interactions ISO RGD:1332312 6480464 Tunicamycin inhibits the reaction [mevastatin results in increased cleavage of XBP1 protein] CTD PMID:16330322 minocycline multiple interactions EXP 6480464 Minocycline inhibits the reaction [Paraquat results in increased expression of XBP1 protein] CTD PMID:22245251 MK-2206 multiple interactions ISO RGD:1352787 6480464 MK 2206 promotes the reaction [Cadmium Chloride results in increased expression of XBP1 protein alternative form] CTD PMID:29444456 N-acetyl-L-cysteine increases splicing ISO RGD:1352787 6480464 Acetylcysteine results in increased splicing of XBP1 mRNA CTD PMID:19722195 N-acetyl-L-cysteine multiple interactions ISO RGD:1352787 6480464 Acetylcysteine inhibits the reaction [Ethylmercury Compounds results in increased splicing of XBP1 mRNA] more ... CTD PMID:21138464 , PMID:27511942 N-acetyl-L-cysteine multiple interactions ISO RGD:1332312 6480464 Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of XBP1 protein alternative form] more ... CTD PMID:21911445 more ... N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of XBP1 protein], Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased splicing of XBP1 mRNA] CTD PMID:21145380 , PMID:30633982 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases response to substance ISO RGD:1352787 6480464 XBP1 protein results in decreased susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde CTD PMID:19135031 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:1352787 6480464 [XBP1 mutant form co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] inhibits the reaction [Tobacco Smoke Pollution analog results in increased phosphorylation of EIF2S1 protein], [XBP1 mutant form co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] promotes the reaction [Tobacco Smoke Pollution analog results in increased cleavage of CASP3 protein] CTD PMID:25568320 N-methyl-4-phenylpyridinium decreases response to substance ISO RGD:1352787 6480464 XBP1 protein results in decreased susceptibility to 1-Methyl-4-phenylpyridinium CTD PMID:19135031 N-methyl-4-phenylpyridinium increases expression ISO RGD:1352787 6480464 1-Methyl-4-phenylpyridinium results in increased expression of XBP1 mRNA CTD PMID:24810058 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of XBP1 mRNA CTD PMID:18164116 nefazodone increases splicing ISO RGD:1352787 6480464 nefazodone results in increased splicing of XBP1 mRNA CTD PMID:27613715 nicotine multiple interactions EXP 6480464 Nicotine inhibits the reaction [Tunicamycin results in increased splicing of XBP1 mRNA] CTD PMID:18477628 nilotinib increases expression ISO RGD:1352787 6480464 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide results in increased expression of XBP1 mRNA alternative form CTD PMID:23883479 Nodularin increases expression ISO RGD:1352787 6480464 nodularin results in increased expression of XBP1 mRNA alternative form CTD PMID:27061667 o-xylene increases expression ISO RGD:1352787 6480464 2-xylene results in increased expression of XBP1 mRNA CTD PMID:20359517 ochratoxin A decreases expression ISO RGD:1352787 6480464 ochratoxin A results in decreased expression of XBP1 mRNA CTD PMID:30559759 okadaic acid increases expression EXP 6480464 Okadaic Acid results in increased expression of XBP1 protein CTD PMID:26732598 orlistat multiple interactions ISO RGD:1352787 6480464 orlistat affects the reaction [ERN1 protein affects the splicing of XBP1 mRNA] CTD PMID:17283163 paclitaxel multiple interactions ISO RGD:1352787 6480464 [Paclitaxel co-treated with Metformin] results in decreased expression of XBP1 mRNA CTD PMID:29309887 paracetamol affects expression ISO RGD:1332312 6480464 Acetaminophen affects the expression of XBP1 mRNA CTD PMID:17562736 paracetamol decreases expression ISO RGD:1352787 6480464 Acetaminophen results in decreased expression of XBP1 mRNA CTD PMID:21420995 paracetamol multiple interactions ISO RGD:1332312 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of XBP1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of XBP1 mRNA] CTD PMID:17585979 paraquat multiple interactions EXP 6480464 Minocycline inhibits the reaction [Paraquat results in increased expression of XBP1 protein] CTD PMID:22245251 paraquat increases expression EXP 6480464 Paraquat results in increased expression of XBP1 protein CTD PMID:22245251 patulin increases splicing ISO RGD:1352787 6480464 Patulin results in increased splicing of XBP1 mRNA CTD PMID:21844328 , PMID:25577197 phenobarbital increases expression ISO RGD:1332312 6480464 Phenobarbital results in increased expression of XBP1 mRNA CTD PMID:25270620 phenobarbital affects expression ISO RGD:1332312 6480464 Phenobarbital affects the expression of XBP1 mRNA CTD PMID:23091169 picene decreases expression ISO RGD:1352787 6480464 picene results in decreased expression of XBP1 mRNA CTD PMID:32251684 pirinixic acid decreases expression ISO RGD:1332312 6480464 pirinixic acid results in decreased expression of XBP1 mRNA CTD PMID:20813756 , PMID:23811191 potassium iodide multiple interactions ISO RGD:1352787 6480464 Potassium Iodide inhibits the reaction [Sodium Fluoride results in increased splicing of XBP1 mRNA] CTD PMID:24231001 prallethrin increases activity ISO RGD:1352787 6480464 d, d-T80-prallethrin results in increased activity of XBP1 protein CTD PMID:20143881 progesterone increases expression ISO RGD:1352787 6480464 Progesterone results in increased expression of XBP1 mRNA CTD PMID:18037150 pyrazinecarboxamide increases expression ISO RGD:1352787 6480464 Pyrazinamide results in increased expression of XBP1 mRNA alternative form CTD PMID:28063906 quercetin multiple interactions ISO RGD:1332312 6480464 Quercetin inhibits the reaction [4-nitrophenol results in increased expression of XBP1 mRNA] CTD PMID:23997041 quercetin increases expression ISO RGD:1352787 6480464 Quercetin results in increased expression of XBP1 protein CTD PMID:30152185 quercetin increases splicing ISO RGD:1352787 6480464 Quercetin results in increased splicing of XBP1 mRNA CTD PMID:19017364 more ... quercetin decreases expression ISO RGD:1352787 6480464 Quercetin results in decreased expression of XBP1 mRNA CTD PMID:21632981 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [[Sincalide co-treated with Palmitic Acid] results in increased expression of XBP1 protein alternative form] more ... CTD PMID:26873426 quercetin multiple interactions ISO RGD:1352787 6480464 3 more ... CTD PMID:19017364 more ... reactive oxygen species multiple interactions ISO RGD:1352787 6480464 Acetylcysteine inhibits the reaction [XBP1 protein inhibits the reaction [Arsenic Trioxide results in increased abundance of Reactive Oxygen Species]] more ... CTD PMID:21138464 reactive oxygen species decreases expression ISO RGD:1352787 6480464 Reactive Oxygen Species results in decreased expression of XBP1 mRNA CTD PMID:25800948 resveratrol increases splicing ISO RGD:1352787 6480464 resveratrol results in increased splicing of XBP1 mRNA CTD PMID:17914584 , PMID:20198347 resveratrol multiple interactions EXP 6480464 Resveratrol inhibits the reaction [Cadmium Chloride results in increased expression of XBP1 mRNA], Resveratrol inhibits the reaction [Cadmium Chloride results in increased expression of XBP1 protein] CTD PMID:31433112 resveratrol multiple interactions ISO RGD:1352787 6480464 Resveratrol inhibits the reaction [Cadmium Chloride results in increased expression of XBP1 protein alternative form] CTD PMID:30796460 resveratrol multiple interactions ISO RGD:1332312 6480464 [resveratrol results in decreased activity of MTOR protein] inhibits the reaction [Tunicamycin results in increased expression of XBP1 mRNA alternative form] CTD PMID:21321189 Riluzole increases expression ISO RGD:1352787 6480464 Riluzole results in increased expression of XBP1 protein CTD PMID:30280407 rotenone decreases expression ISO RGD:1332312 6480464 Rotenone results in decreased expression of XBP1 mRNA CTD PMID:23186747 rotenone multiple interactions ISO RGD:1352787 6480464 MIR384 mRNA promotes the reaction [Rotenone results in increased expression of XBP1 protein], Rotenone results in increased expression of and results in increased splicing of XBP1 mRNA CTD PMID:26864693 , PMID:27345029 rotenone increases expression ISO RGD:1352787 6480464 Rotenone results in increased expression of XBP1 protein CTD PMID:26864693 SB 431542 multiple interactions ISO RGD:1352787 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of XBP1 mRNA CTD PMID:27188386 SCH 23390 multiple interactions EXP 6480464 SCH 23390 inhibits the reaction [Methamphetamine results in increased splicing of XBP1 mRNA] CTD PMID:19564919 serpentine asbestos increases splicing ISO RGD:1352787 6480464 Asbestos, Serpentine results in increased splicing of XBP1 mRNA CTD PMID:25324550 serpentine asbestos increases splicing ISO RGD:1332312 6480464 Asbestos, Serpentine results in increased splicing of XBP1 mRNA CTD PMID:25324550 sertraline increases splicing ISO RGD:1352787 6480464 Sertraline results in increased splicing of XBP1 mRNA CTD PMID:24865413 silicon dioxide decreases expression ISO RGD:1352787 6480464 Silicon Dioxide analog results in decreased expression of XBP1 mRNA CTD PMID:25895662 silicon dioxide multiple interactions ISO RGD:1352787 6480464 [Silicon Dioxide analog co-treated with Silver] results in increased splicing of XBP1 mRNA CTD PMID:22245057 silicon dioxide increases splicing ISO RGD:1352787 6480464 Silicon Dioxide analog results in increased splicing of XBP1 mRNA CTD PMID:22245057 silver atom multiple interactions ISO RGD:1352787 6480464 [Silicon Dioxide analog co-treated with Silver] results in increased splicing of XBP1 mRNA CTD PMID:22245057 silver(0) multiple interactions ISO RGD:1352787 6480464 [Silicon Dioxide analog co-treated with Silver] results in increased splicing of XBP1 mRNA CTD PMID:22245057 simvastatin decreases expression EXP 6480464 Simvastatin results in decreased expression of XBP1 protein CTD PMID:18807172 sincalide multiple interactions EXP 6480464 [Palmitic Acid co-treated with Sincalide] results in increased expression of XBP1 mRNA alternative form more ... CTD PMID:26873426 sirolimus multiple interactions ISO RGD:1352787 6480464 Sirolimus inhibits the reaction [arsenite results in increased splicing of XBP1 mRNA] CTD PMID:22215663 sodium arsenate increases expression ISO RGD:1332312 6480464 sodium arsenate analog results in increased expression of XBP1 mRNA, sodium arsenate analog results in increased expression of XBP1 mRNA alternative form CTD PMID:23221991 sodium arsenite multiple interactions ISO RGD:1352787 6480464 sodium arsenite promotes the reaction [[XBP1 protein binds to HIF1A protein] which binds to ACE enhancer] more ... CTD PMID:28973481 sodium arsenite decreases expression ISO RGD:1352787 6480464 sodium arsenite results in decreased expression of XBP1 mRNA CTD PMID:28595984 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of XBP1 protein CTD PMID:17645694 , PMID:17681577 sodium arsenite multiple interactions EXP 6480464 Melatonin inhibits the reaction [sodium arsenite results in increased expression of XBP1 protein] CTD PMID:17645694 sodium arsenite increases expression ISO RGD:1332312 6480464 sodium arsenite results in increased expression of XBP1 mRNA more ... CTD PMID:21911445 , PMID:23221991 sodium arsenite decreases expression ISO RGD:1332312 6480464 sodium arsenite results in decreased expression of XBP1 mRNA CTD PMID:19822182 sodium arsenite affects splicing ISO RGD:1332312 6480464 sodium arsenite affects the splicing of XBP1 mRNA CTD PMID:21911445 sodium arsenite affects localization ISO RGD:1332312 6480464 sodium arsenite affects the localization of XBP1 protein CTD PMID:21911445 sodium arsenite multiple interactions ISO RGD:1332312 6480464 Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of XBP1 protein alternative form] CTD PMID:21911445 sodium fluoride affects expression EXP 6480464 Sodium Fluoride affects the expression of XBP1 mRNA CTD PMID:25132241 sodium fluoride increases splicing EXP 6480464 Sodium Fluoride results in increased splicing of XBP1 mRNA CTD PMID:30633982 sodium fluoride multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased splicing of XBP1 mRNA] CTD PMID:30633982 sodium fluoride increases splicing ISO RGD:1352787 6480464 Sodium Fluoride results in increased splicing of XBP1 mRNA CTD PMID:24231001 sodium fluoride multiple interactions ISO RGD:1352787 6480464 Potassium Iodide inhibits the reaction [Sodium Fluoride results in increased splicing of XBP1 mRNA] CTD PMID:24231001 sodium fluoride increases expression ISO RGD:1332312 6480464 Sodium Fluoride results in increased expression of XBP1 mRNA, Sodium Fluoride results in increased expression of XBP1 protein CTD PMID:21626649 sodium fluoride decreases expression EXP 6480464 Sodium Fluoride results in decreased expression of XBP1 protein modified form CTD PMID:18696052 sorafenib increases splicing ISO RGD:1352787 6480464 sorafenib results in increased splicing of XBP1 mRNA CTD PMID:17548474 SR 144528 multiple interactions ISO RGD:1352787 6480464 [Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of XBP1 mRNA alternative form] CTD PMID:31054322 sulfasalazine multiple interactions ISO RGD:1352787 6480464 [Hydroxychloroquine co-treated with Methotrexate co-treated with Sulfasalazine] results in decreased expression of XBP1 mRNA CTD PMID:28863153 sulforaphane multiple interactions ISO RGD:1352787 6480464 sulforafan promotes the reaction [arsenic trioxide results in increased splicing of XBP1 mRNA] CTD PMID:22922937 sulindac increases expression ISO RGD:1352787 6480464 Sulindac results in increased expression of XBP1 mRNA CTD PMID:11906190 sunitinib increases expression ISO RGD:1352787 6480464 Sunitinib results in increased expression of XBP1 mRNA CTD PMID:31533062 T-2 Toxin increases expression ISO RGD:1332312 6480464 T-2 Toxin results in increased expression of XBP1 protein alternative form CTD PMID:31170431 T-2 Toxin decreases expression ISO RGD:1352787 6480464 T-2 Toxin results in decreased expression of XBP1 mRNA CTD PMID:31863870 T-2 Toxin increases expression ISO RGD:1352787 6480464 T-2 Toxin results in increased expression of XBP1 protein alternative form CTD PMID:31170431 tacrolimus hydrate increases expression ISO RGD:1332312 6480464 Tacrolimus results in increased expression of XBP1 mRNA CTD PMID:25270620 tacrolimus hydrate multiple interactions ISO RGD:1332312 6480464 Tacrolimus results in increased expression of and affects the localization of XBP1 protein modified form CTD PMID:23958496 tamibarotene increases expression ISO RGD:1352787 6480464 tamibarotene results in increased expression of XBP1 mRNA CTD PMID:17229644 tamoxifen affects expression ISO RGD:1332312 6480464 Tamoxifen affects the expression of XBP1 mRNA CTD PMID:17555576 tauroursodeoxycholic acid multiple interactions ISO RGD:1352787 6480464 tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA], tauroursodeoxycholic acid inhibits the reaction [Quercetin results in increased splicing of XBP1 mRNA] CTD PMID:20165829 , PMID:25611565 tauroursodeoxycholic acid multiple interactions EXP 6480464 tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA] CTD PMID:20165829 tetrachloromethane multiple interactions ISO RGD:1332312 6480464 1-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea inhibits the reaction [Carbon Tetrachloride results in increased expression of XBP1 mRNA] more ... CTD PMID:25827057 , PMID:30538632 tetrachloromethane increases splicing ISO RGD:1332312 6480464 Carbon Tetrachloride results in increased splicing of XBP1 mRNA CTD PMID:30538632 tetrachloromethane increases expression ISO RGD:1332312 6480464 Carbon Tetrachloride results in increased expression of XBP1 mRNA, Carbon Tetrachloride results in increased expression of XBP1 protein CTD PMID:25827057 tetraphene multiple interactions ISO RGD:1332312 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of XBP1 mRNA CTD PMID:27858113 thapsigargin multiple interactions ISO RGD:1352787 6480464 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased expression of XBP1 protein] more ... CTD PMID:17917237 more ... thapsigargin increases cleavage ISO RGD:1352787 6480464 Thapsigargin results in increased cleavage of XBP1 mRNA CTD PMID:19946333 thapsigargin increases splicing EXP 6480464 Thapsigargin results in increased splicing of XBP1 mRNA CTD PMID:18477628 , PMID:24638036 thapsigargin increases splicing ISO RGD:1332312 6480464 Thapsigargin results in increased splicing of XBP1 mRNA CTD PMID:25324550 thapsigargin increases expression ISO RGD:1352787 6480464 Thapsigargin results in increased expression of XBP1 mRNA more ... CTD PMID:17917237 more ... thapsigargin increases activity ISO RGD:1352787 6480464 Thapsigargin results in increased activity of XBP1 protein CTD PMID:20816668 , PMID:23383089 thapsigargin decreases response to substance ISO RGD:1352787 6480464 XBP1 protein results in decreased susceptibility to Thapsigargin CTD PMID:19135031 thapsigargin increases expression ISO RGD:1332312 6480464 Thapsigargin results in increased expression of XBP1 mRNA, Thapsigargin results in increased expression of XBP1 protein CTD PMID:20589738 more ... thapsigargin multiple interactions ISO RGD:1332312 6480464 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased expression of XBP1 protein] more ... CTD PMID:22509299 more ... thapsigargin affects splicing ISO RGD:1352787 6480464 Thapsigargin affects the splicing of XBP1 mRNA CTD PMID:23885834 thapsigargin affects localization EXP 6480464 Thapsigargin affects the localization of XBP1 protein CTD PMID:16338971 thapsigargin increases splicing ISO RGD:1352787 6480464 Thapsigargin results in increased splicing of XBP1 mRNA CTD PMID:17353921 more ... titanium dioxide increases expression ISO RGD:1332312 6480464 titanium dioxide results in increased expression of XBP1 mRNA, titanium dioxide results in increased expression of XBP1 protein alternative form CTD PMID:23409001 more ... titanium dioxide multiple interactions ISO RGD:1332312 6480464 4-phenylbutyric acid inhibits the reaction [titanium dioxide results in increased expression of XBP1 protein alternative form], 4-phenylbutyric acid inhibits the reaction [titanium dioxide results in increased splicing of XBP1 mRNA] CTD PMID:31298478 titanium dioxide increases splicing ISO RGD:1332312 6480464 titanium dioxide results in increased splicing of XBP1 mRNA CTD PMID:31298478 , PMID:31769605 toluene increases expression ISO RGD:1352787 6480464 Toluene results in increased expression of XBP1 mRNA CTD PMID:20359517 tributylstannane increases splicing ISO RGD:1352787 6480464 tributyltin results in increased splicing of XBP1 mRNA CTD PMID:23743301 Tributyltin oxide increases expression ISO RGD:1352787 6480464 bis(tri-n-butyltin)oxide results in increased expression of XBP1 mRNA CTD PMID:21601586 Tributyltin oxide increases expression ISO RGD:1332312 6480464 bis(tri-n-butyltin)oxide results in increased expression of XBP1 mRNA CTD PMID:22434021 trichloroethene increases expression ISO RGD:1352787 6480464 Trichloroethylene results in increased expression of XBP1 mRNA CTD PMID:20359517 trichostatin A increases expression ISO RGD:1352787 6480464 trichostatin A results in increased expression of XBP1 mRNA CTD PMID:24935251 trichostatin A affects expression ISO RGD:1352787 6480464 trichostatin A affects the expression of XBP1 mRNA CTD PMID:28542535 trierixin multiple interactions ISO RGD:1352787 6480464 trierixin inhibits the reaction [Thapsigargin results in increased expression of XBP1 mRNA], trierixin inhibits the reaction [Thapsigargin results in increased splicing of XBP1 mRNA] CTD PMID:17917237 troglitazone decreases expression EXP 6480464 troglitazone results in decreased expression of XBP1 mRNA CTD PMID:25596134 trovafloxacin increases expression EXP 6480464 trovafloxacin results in increased expression of XBP1 mRNA CTD PMID:24136188 tunicamycin multiple interactions ISO RGD:1332312 6480464 [ATG5 protein mutant form results in increased susceptibility to Tunicamycin] which results in increased expression of XBP1 mRNA more ... CTD PMID:16330322 more ... tunicamycin increases splicing ISO RGD:1332312 6480464 Tunicamycin results in increased splicing of XBP1 mRNA CTD PMID:16330322 more ... tunicamycin increases splicing EXP 6480464 Tunicamycin results in increased splicing of XBP1 mRNA CTD PMID:18477628 , PMID:24291486 tunicamycin increases splicing ISO RGD:1352787 6480464 Tunicamycin results in increased splicing of XBP1 mRNA CTD PMID:19135031 more ... tunicamycin multiple interactions ISO RGD:1352787 6480464 SIRT7 protein inhibits the reaction [Tunicamycin results in increased splicing of XBP1 mRNA] more ... CTD PMID:17917237 more ... tunicamycin increases expression ISO RGD:1352787 6480464 Tunicamycin results in increased expression of XBP1 mRNA, Tunicamycin results in increased expression of XBP1 protein CTD PMID:22378314 more ... tunicamycin increases expression ISO RGD:1332312 6480464 Tunicamycin results in increased expression of XBP1 mRNA, Tunicamycin results in increased expression of XBP1 mRNA alternative form CTD PMID:21321189 more ... tunicamycin multiple interactions EXP 6480464 Nicotine inhibits the reaction [Tunicamycin results in increased splicing of XBP1 mRNA] CTD PMID:18477628 urethane decreases expression ISO RGD:1352787 6480464 Urethane results in decreased expression of XBP1 mRNA CTD PMID:28818685 usnic acid increases splicing ISO RGD:1352787 6480464 usnic acid results in increased splicing of XBP1 mRNA CTD PMID:25870318 valproic acid affects expression ISO RGD:1332312 6480464 Valproic Acid affects the expression of XBP1 mRNA CTD PMID:17292431 valproic acid affects expression ISO RGD:1352787 6480464 Valproic Acid affects the expression of XBP1 mRNA CTD PMID:25979313 valproic acid decreases expression ISO RGD:1352787 6480464 Valproic Acid results in decreased expression of XBP1 mRNA CTD PMID:29154799 vitamin E increases expression ISO RGD:1352787 6480464 alpha-Tocopherol analog results in increased expression of XBP1 mRNA CTD PMID:20686688 withaferin A increases expression ISO RGD:1352787 6480464 withaferin A results in increased expression of XBP1 protein CTD PMID:21266191 withaferin A increases splicing ISO RGD:1352787 6480464 withaferin A results in increased splicing of XBP1 mRNA CTD PMID:21266191 zearalenone increases expression ISO RGD:1352787 6480464 Zearalenone results in increased expression of XBP1 mRNA CTD PMID:28965971 zinc oxide increases expression ISO RGD:1332312 6480464 Zinc Oxide analog results in increased expression of XBP1 mRNA CTD PMID:25680694
Gene-Chemical Interaction Annotations
