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Gene: Xbp1 (X-box binding protein 1) Rattus norvegicus
Symbol: Xbp1
Name: X-box binding protein 1
Description: Exhibits DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in several processes, including endoplasmic reticulum unfolded protein response; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; and serotonin secretion, neurotransmission. Localizes to nucleus. Biomarker of borna disease. Orthologous to human XBP1 (X-box binding protein 1); PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; forkhead class A signaling pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (R)-noradrenaline; (S)-nicotine; 2-amino-2-deoxy-D-glucopyranose.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: hepatocarcinogenesis-related transcription factor; HTF; X-box-binding protein 1
Homo sapiens (human) : XBP1 (X-box binding protein 1)  HGNC  Alliance
Mus musculus (house mouse) : Xbp1 (X-box binding protein 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xbp1 (X-box binding protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : XBP1 (X-box binding protein 1)
Canis lupus familiaris (dog) : XBP1 (X-box binding protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xbp1 (X-box binding protein 1)
Sus scrofa (pig) : XBP1 (X-box binding protein 1)
Chlorocebus sabaeus (African green monkey) : XBP1 (X-box binding protein 1)
Heterocephalus glaber (naked mole-rat) : Xbp1 (X-box binding protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01485,753,736 - 85,758,820 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1485,753,760 - 85,758,145 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01486,423,839 - 86,428,923 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41486,151,910 - 86,156,975 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11486,171,054 - 86,176,119 (+)NCBI
Celera1479,276,264 - 79,281,348 (+)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Xbp1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1303073
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.