Xbp1 (X-box binding protein 1) - Rat Genome Database

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Gene: Xbp1 (X-box binding protein 1) Rattus norvegicus
Analyze
Symbol: Xbp1
Name: X-box binding protein 1
RGD ID: 1303073
Description: Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in several processes, including endoplasmic reticulum unfolded protein response; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; and serotonin secretion, neurotransmission. Located in cytoplasm and nucleus. Biomarker of borna disease. Orthologous to human XBP1 (X-box binding protein 1); PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; forkhead class A signaling pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (R)-noradrenaline; (S)-nicotine; 2-amino-2-deoxy-D-glucopyranose.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: hepatocarcinogenesis-related transcription factor; HTF; X-box-binding protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21480,390,629 - 80,395,713 (+)NCBImRatBN7.2
Rnor_6.0 Ensembl1485,753,760 - 85,758,145 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01485,753,736 - 85,758,820 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01486,423,839 - 86,428,923 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41486,151,910 - 86,156,975 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11486,171,054 - 86,176,119 (+)NCBI
Celera1479,276,264 - 79,281,348 (+)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-alpha-tocopherol  (ISO)
(+)-catechin  (ISO)
(-)-anisomycin  (ISO)
(R)-noradrenaline  (EXP)
(S)-nicotine  (EXP)
1-[2-(3,4-dichlorophenyl)ethyl]-4-methylpiperazine  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dichlorophenol  (ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP,ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4-aminophenol  (EXP)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (ISO)
4-nitrophenol  (ISO)
4-phenylbutyric acid  (EXP,ISO)
5-fluorouracil  (ISO)
8-Br-cAMP  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (EXP,ISO)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (ISO)
Aloe emodin  (ISO)
alpha-pinene  (ISO)
AM-251  (ISO)
amiloride  (ISO)
amiodarone  (ISO)
ammonium chloride  (EXP)
amosite asbestos  (ISO)
antimycin A  (EXP)
antirheumatic drug  (ISO)
aristolochic acid  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP,ISO)
atrazine  (ISO)
benzalkonium chloride  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
benzoates  (ISO)
beta-D-glucosamine  (EXP,ISO)
beta-naphthoflavone  (EXP)
bexarotene  (ISO)
bilirubin IXalpha  (ISO)
bisphenol A  (EXP,ISO)
boric acid  (ISO)
bortezomib  (ISO)
brefeldin A  (ISO)
bromobenzene  (EXP)
bupropion  (ISO)
butan-1-ol  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
Calcimycin  (ISO)
cannabidiol  (ISO)
captan  (ISO)
carbamazepine  (ISO)
carbaryl  (ISO)
carbon nanotube  (ISO)
casticin  (ISO)
cerulenin  (ISO)
ceruletide  (EXP)
chloroacetaldehyde  (ISO)
chloroacetic acid  (ISO)
chloropicrin  (ISO)
chlorpromazine  (EXP)
chlorpyrifos  (ISO)
choline  (ISO)
chrysene  (ISO)
cidofovir anhydrous  (ISO)
cisplatin  (EXP,ISO)
clodronic acid  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP,ISO)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
curcumin  (ISO)
cyclosporin A  (EXP,ISO)
D-glucose  (EXP,ISO)
D-penicillamine  (ISO)
dantrolene  (ISO)
deoxynivalenol  (ISO)
desferrioxamine B  (ISO)
diarsenic trioxide  (EXP,ISO)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (EXP,ISO)
dichloromethane  (ISO)
diclofenac  (ISO)
dimethylarsinic acid  (ISO)
dioxygen  (EXP,ISO)
disodium selenite  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ebselen  (EXP)
endosulfan  (EXP)
entinostat  (ISO)
erlotinib hydrochloride  (EXP)
ethanol  (ISO)
ethylbenzene  (ISO)
fenofibrate  (EXP,ISO)
ferric ammonium citrate  (ISO)
flutamide  (EXP)
folic acid  (ISO)
folpet  (ISO)
fructose  (ISO)
furan  (EXP)
gadolinium trichloride  (EXP)
gemcitabine  (ISO)
gentamycin  (EXP)
geraniol  (ISO)
glucose  (EXP,ISO)
glutathione  (ISO)
glycine  (ISO)
glycyrrhetinate  (ISO)
glycyrrhetinic acid  (ISO)
hexadecanoic acid  (EXP,ISO)
homocysteine  (ISO)
hydrogen peroxide  (ISO)
hydroxychloroquine  (ISO)
ibuprofen  (ISO)
ifosfamide  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
indometacin  (ISO)
indoxyl sulfate  (ISO)
L-methionine  (ISO)
lactacystin  (ISO)
lanthanum atom  (ISO)
leflunomide  (ISO)
letrozole  (EXP)
linuron  (ISO)
lipopolysaccharide  (ISO)
luteolin  (ISO)
manganese atom  (EXP)
manganese(0)  (EXP)
manganese(II) chloride  (EXP)
melatonin  (EXP)
menadione  (ISO)
metformin  (EXP,ISO)
methamphetamine  (EXP,ISO)
methotrexate  (ISO)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
mevastatin  (ISO)
minocycline  (EXP)
MK-2206  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (ISO)
nicotine  (EXP)
nilotinib  (ISO)
Nodularin  (ISO)
o-xylene  (ISO)
ochratoxin A  (ISO)
okadaic acid  (EXP)
oleic acid  (ISO)
orlistat  (ISO)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
patulin  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
picene  (ISO)
pirinixic acid  (ISO)
potassium iodide  (ISO)
prallethrin  (ISO)
progesterone  (ISO)
pyrazinecarboxamide  (ISO)
quercetin  (EXP,ISO)
reactive oxygen species  (ISO)
resveratrol  (EXP,ISO)
Riluzole  (ISO)
rimonabant  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
SCH 23390  (EXP)
serpentine asbestos  (ISO)
sertraline  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (EXP)
sincalide  (EXP)
sirolimus  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP,ISO)
sorafenib  (ISO)
SR 144528  (ISO)
streptozocin  (EXP)
sulfasalazine  (ISO)
sulforaphane  (ISO)
sulfur dioxide  (ISO)
sulindac  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
tacrolimus hydrate  (ISO)
tamibarotene  (ISO)
tamoxifen  (ISO)
tauroursodeoxycholic acid  (EXP,ISO)
temozolomide  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thapsigargin  (EXP,ISO)
titanium dioxide  (ISO)
toluene  (ISO)
tributylstannane  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
trierixin  (ISO)
troglitazone  (EXP)
trovafloxacin  (EXP)
tunicamycin  (EXP,ISO)
urethane  (ISO)
usnic acid  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
withaferin A  (ISO)
zearalenone  (ISO)
zinc oxide  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adipose tissue development  (ISO,ISS)
angiogenesis  (ISO,ISS)
cellular response to amino acid stimulus  (ISO,ISS)
cellular response to antibiotic  (IEP)
cellular response to fluid shear stress  (ISO,ISS)
cellular response to fructose stimulus  (ISO)
cellular response to glucose starvation  (ISO,ISS)
cellular response to glucose stimulus  (ISO)
cellular response to insulin stimulus  (ISO)
cellular response to interleukin-4  (ISO,ISS)
cellular response to laminar fluid shear stress  (ISO,ISS)
cellular response to leukemia inhibitory factor  (ISO)
cellular response to lipopolysaccharide  (IEA,ISO,ISS)
cellular response to nutrient  (ISO)
cellular response to oxidative stress  (ISO)
cellular response to peptide hormone stimulus  (ISO,ISS)
cellular response to vascular endothelial growth factor stimulus  (ISO)
cellular triglyceride homeostasis  (ISO,ISS)
cholesterol homeostasis  (ISO,ISS)
endoplasmic reticulum unfolded protein response  (IDA,ISO)
endothelial cell proliferation  (ISO,ISS)
epithelial cell maturation  (ISO)
epithelial cell maturation involved in salivary gland development  (ISO)
exocrine pancreas development  (ISO)
fatty acid homeostasis  (ISO,ISS)
glucose homeostasis  (ISO)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress  (ISO)
liver development  (ISO,ISS)
muscle organ development  (IEA)
negative regulation of apoptotic process  (ISO,ISS)
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway  (IEA,IMP,ISO)
negative regulation of endoplasmic reticulum unfolded protein response  (ISO)
negative regulation of ERK1 and ERK2 cascade  (ISO)
negative regulation of myotube differentiation  (ISO)
negative regulation of pathway-restricted SMAD protein phosphorylation  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
negative regulation of transforming growth factor beta receptor signaling pathway  (ISO)
neuron development  (ISO)
phosphatidylinositol 3-kinase signaling  (ISO)
positive regulation of angiogenesis  (ISO)
positive regulation of autophagy  (ISO)
positive regulation of B cell differentiation  (ISO,ISS)
positive regulation of cell migration  (IEA,ISO)
positive regulation of cell population proliferation  (IEA,ISO)
positive regulation of endoplasmic reticulum unfolded protein response  (IEA,ISO)
positive regulation of endothelial cell apoptotic process  (ISO)
positive regulation of fat cell differentiation  (ISO,ISS)
positive regulation of hepatocyte proliferation  (ISO,ISS)
positive regulation of histone methylation  (ISO)
positive regulation of immunoglobulin production  (IEA,ISO,ISS)
positive regulation of interleukin-6 production  (ISO)
positive regulation of lactation  (ISO,ISS)
positive regulation of MHC class II biosynthetic process  (IEA,ISO,ISS)
positive regulation of plasma cell differentiation  (IEA,ISO,ISS)
positive regulation of proteasomal protein catabolic process  (ISO)
positive regulation of protein acetylation  (ISO)
positive regulation of protein import into nucleus  (ISO)
positive regulation of protein kinase B signaling  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of T cell differentiation  (IEA,ISO,ISS)
positive regulation of TOR signaling  (ISO)
positive regulation of transcription by RNA polymerase II  (IEA,ISO,ISS)
positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response  (IBA,ISO,ISS)
positive regulation of vascular associated smooth muscle cell migration  (ISO)
positive regulation of vascular associated smooth muscle cell proliferation  (ISO)
positive regulation of vascular wound healing  (IEA,ISO)
protein destabilization  (ISO,ISS)
regulation of autophagy  (ISO,ISS)
regulation of cell growth  (ISO)
regulation of protein stability  (ISO)
regulation of transcription by RNA polymerase II  (ISO)
regulation of transcription, DNA-templated  (TAS)
response to electrical stimulus  (IDA)
response to endoplasmic reticulum stress  (ISO)
response to insulin-like growth factor stimulus  (ISO,ISS)
response to xenobiotic stimulus  (IDA)
serotonin secretion, neurotransmission  (IDA)
sterol homeostasis  (ISO,ISS)
transcription by RNA polymerase II  (IDA,ISO)
ubiquitin-dependent protein catabolic process  (ISO,ISS)
vascular endothelial growth factor receptor signaling pathway  (ISO)

Cellular Component

References

References - curated
1. Baryshev M, etal., J Mol Endocrinol 2004 Jun;32(3):903-20.
2. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. GOA data from the GO Consortium
4. Gupta S, etal., PLoS Biol. 2010 Jul 6;8(7):e1000410. doi: 10.1371/journal.pbio.1000410.
5. Liu A, etal., Sci Rep. 2019 Dec 13;9(1):19043. doi: 10.1038/s41598-019-55557-1.
6. MGD data from the GO Consortium
7. Nakamura S, etal., J Biol Chem. 2009 May 29;284(22):14809-18. doi: 10.1074/jbc.M901488200. Epub 2009 Mar 30.
8. OMIM Disease Annotation Pipeline
9. Ozcan U, etal., Science. 2004 Oct 15;306(5695):457-61.
10. Pfaffenbach KT, etal., J Nutr. 2010 May;140(5):879-84. Epub 2010 Mar 17.
11. Pipeline to import KEGG annotations from KEGG into RGD
12. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
13. Ren F, etal., J Viral Hepat. 2016 Jan;23(1):23-31. doi: 10.1111/jvh.12438. Epub 2015 Jul 31.
14. RGD automated data pipeline
15. RGD automated import pipeline for gene-chemical interactions
16. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
17. Tan Z, etal., J Neuroinflammation. 2018 Sep 21;15(1):275. doi: 10.1186/s12974-018-1311-5.
18. Toda H, etal., Brain Res. 2006 Sep 27;1112(1):26-32. Epub 2006 Aug 2.
19. Wang S and Kaufman RJ, J Cell Biol. 2012 Jun 25;197(7):857-67. doi: 10.1083/jcb.201110131.
20. Williams BL and Lipkin WI, J Virol. 2006 Sep;80(17):8613-26. doi: 10.1128/JVI.00836-06.
Additional References at PubMed
PMID:1903538   PMID:2196176   PMID:8657566   PMID:10652269   PMID:10675042   PMID:11460154   PMID:11779464   PMID:12612580   PMID:12805554   PMID:14559994   PMID:15489334   PMID:16332684  
PMID:16362047   PMID:16461360   PMID:16645094   PMID:17612490   PMID:17715997   PMID:18556558   PMID:18946015   PMID:19135031   PMID:19328063   PMID:20102225   PMID:20170659   PMID:20348923  
PMID:20348926   PMID:20349222   PMID:20408817   PMID:20439489   PMID:20955178   PMID:21317886   PMID:21337367   PMID:21436843   PMID:21784843   PMID:22529213   PMID:22580202   PMID:22715395  
PMID:22970712   PMID:23152784   PMID:23184933   PMID:23457509   PMID:23508570   PMID:23529610   PMID:23623498   PMID:24333444   PMID:24753614   PMID:25007519   PMID:25190803   PMID:25239945  
PMID:25280941   PMID:25656649   PMID:26315405   PMID:26319553   PMID:26883836   PMID:27133203   PMID:27929749   PMID:27957794   PMID:29414031   PMID:29956773   PMID:30317635   PMID:32199617  
PMID:33055426   PMID:33395585  


Genomics

Comparative Map Data
Xbp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21480,390,629 - 80,395,713 (+)NCBImRatBN7.2
Rnor_6.0 Ensembl1485,753,760 - 85,758,145 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01485,753,736 - 85,758,820 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01486,423,839 - 86,428,923 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41486,151,910 - 86,156,975 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11486,171,054 - 86,176,119 (+)NCBI
Celera1479,276,264 - 79,281,348 (+)NCBICelera
Cytogenetic Map14q21NCBI
XBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2228,794,555 - 28,800,597 (-)EnsemblGRCh38hg38GRCh38
GRCh382228,794,560 - 28,800,569 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372229,190,548 - 29,196,557 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362227,520,548 - 27,526,560 (-)NCBINCBI36hg18NCBI36
Build 342227,515,102 - 27,521,114NCBI
Celera2212,990,518 - 12,996,530 (-)NCBI
Cytogenetic Map22q12.1NCBI
HuRef2212,155,463 - 12,161,487 (-)NCBIHuRef
CHM1_12229,149,582 - 29,155,594 (-)NCBICHM1_1
Xbp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,470,641 - 5,475,993 (+)NCBIGRCm39mm39
GRCm39 Ensembl115,470,659 - 5,475,893 (+)Ensembl
GRCm38115,520,641 - 5,525,993 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,520,659 - 5,525,893 (+)EnsemblGRCm38mm10GRCm38
MGSCv37115,420,970 - 5,425,875 (+)NCBIGRCm37mm9NCBIm37
MGSCv36115,420,970 - 5,425,875 (+)NCBImm8
Celera116,013,954 - 6,018,865 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map113.61NCBI
Xbp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554553,037,885 - 3,041,827 (-)NCBIChiLan1.0ChiLan1.0
XBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12227,566,423 - 27,572,627 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2227,567,041 - 27,571,943 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0229,863,479 - 9,869,491 (-)NCBIMhudiblu_PPA_v0panPan3
XBP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12622,162,675 - 22,168,149 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2622,163,222 - 22,168,105 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2622,034,265 - 22,039,738 (-)NCBI
ROS_Cfam_1.02622,536,044 - 22,541,803 (-)NCBI
UMICH_Zoey_3.12622,246,365 - 22,251,835 (-)NCBI
UNSW_CanFamBas_1.02622,509,837 - 22,515,563 (-)NCBI
UU_Cfam_GSD_1.02622,572,658 - 22,578,379 (-)NCBI
Xbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118112,975,309 - 112,979,534 (+)NCBI
SpeTri2.0NW_0049366572,891,171 - 2,895,409 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
XBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1446,008,377 - 46,017,036 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11446,011,239 - 46,016,526 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21449,015,849 - 49,016,650 (-)NCBISscrofa10.2Sscrofa10.2susScr3
XBP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11911,670,605 - 11,677,168 (-)NCBI
Vero_WHO_p1.0NW_023666045114,476,586 - 114,483,163 (+)NCBI
Xbp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247475,123,085 - 5,128,465 (-)NCBI

Position Markers
D14Wox29  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21480,391,337 - 80,391,552 (+)MAPPERmRatBN7.2
Rnor_6.01485,754,445 - 85,754,659NCBIRnor6.0
Rnor_5.01486,424,548 - 86,424,762UniSTSRnor5.0
RGSC_v3.41486,152,600 - 86,152,814UniSTSRGSC3.4
Celera1479,276,973 - 79,277,187UniSTS
Cytogenetic Map14q21UniSTS
RH130248  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21480,395,444 - 80,395,624 (+)MAPPERmRatBN7.2
Rnor_6.01485,758,552 - 85,758,731NCBIRnor6.0
Rnor_5.01486,428,655 - 86,428,834UniSTSRnor5.0
RGSC_v3.41486,156,707 - 86,156,886UniSTSRGSC3.4
Celera1479,281,080 - 79,281,259UniSTS
RH 3.4 Map14571.5UniSTS
Cytogenetic Map14q21UniSTS
Xbp1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21480,394,057 - 80,394,147 (+)MAPPERmRatBN7.2
Rnor_6.01485,757,165 - 85,757,254NCBIRnor6.0
Rnor_5.01486,427,268 - 86,427,357UniSTSRnor5.0
Celera1479,279,693 - 79,279,782UniSTS
Cytogenetic Map14q21UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1412680424106641756Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143259392686191589Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1442442731108833671Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1443910761105074364Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1451818462105074364Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1460980905105980905Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1460980905105980905Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)146187332388870994Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1461993178106993178Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1463548095108548095Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)147339146788870994Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1478172765102549388Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)1478172765102549388Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1478172765102549388Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1478172765102549388Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1478172765106641756Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1478446303110402569Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1480049285115493446Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1480049285115493446Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)1485307663106641756Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:166
Count of miRNA genes:127
Interacting mature miRNAs:136
Transcripts:ENSRNOT00000014044
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 40 11 8
Low 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000014044   ⟹   ENSRNOP00000014044
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1485,753,760 - 85,758,145 (+)Ensembl
RefSeq Acc Id: NM_001004210   ⟹   NP_001004210
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21480,390,629 - 80,395,713 (+)NCBI
Rnor_6.01485,753,736 - 85,758,820 (+)NCBI
Rnor_5.01486,423,839 - 86,428,923 (+)NCBI
RGSC_v3.41486,151,910 - 86,156,975 (+)RGD
Celera1479,276,264 - 79,281,348 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001271731   ⟹   NP_001258660
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21480,390,629 - 80,395,713 (+)NCBI
Rnor_6.01485,753,736 - 85,758,820 (+)NCBI
Rnor_5.01486,423,839 - 86,428,923 (+)NCBI
Celera1479,276,264 - 79,281,348 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001004210   ⟸   NM_001004210
- Peptide Label: isoform XBP1(U)
- UniProtKB: Q9R1S4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001258660   ⟸   NM_001271731
- Peptide Label: isoform XBP1(S)
- UniProtKB: Q9R1S4 (UniProtKB/Swiss-Prot),   A0A140TAA7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000014044   ⟸   ENSRNOT00000014044
Protein Domains
bZIP

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699456
Promoter ID:EPDNEW_R9980
Type:multiple initiation site
Name:Xbp1_1
Description:X-box binding protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01485,753,745 - 85,753,805EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303073 AgrOrtholog
Ensembl Genes ENSRNOG00000010298 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000014044 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014044 ENTREZGENE, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7115933 IMAGE-MGC_LOAD
InterPro bZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:289754 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94999 IMAGE-MGC_LOAD
NCBI Gene 289754 ENTREZGENE
Pfam bZIP_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Xbp1 PhenoGen
PROSITE BZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BZIP_BASIC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BRLZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A140TAA7 ENTREZGENE, UniProtKB/TrEMBL
  Q9R1S4 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Xbp1  X-box binding protein 1      Symbol and Name status set to approved 1299863 APPROVED
2005-02-14 Xbp1  X-box binding protein 1      Symbol and Name status set to provisional 70820 PROVISIONAL