Gene: Ppia (peptidylprolyl isomerase A) Rattus norvegicus
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Symbol: Ppia
Name: peptidylprolyl isomerase A
Description: Exhibits cyclosporin A binding activity. Involved in negative regulation of phosphoprotein phosphatase activity. Predicted to localize to the cytosol; nucleus; and protein-containing complex. Used to study epilepsy. Orthologous to human PPIA (peptidylprolyl isomerase A); INTERACTS WITH (+)-alpha-tocopherol; 2,4-dibromophenyl 2,4,5-tribromophenyl ether; 2-amino-2-deoxy-D-galactopyranose.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CYCA; cyclophilin A; cyclosporin A-binding protein; CyP-A; MGC72881; p1B15; p31; peptidyl-prolyl cis-trans isomerase A; peptidylprolyl isomerase A (cyclophilin A); PPIase A; rotamase A
Orthologs:
Homo sapiens (human) : PPIA (peptidylprolyl isomerase A)  HGNC  Alliance
Mus musculus (house mouse) : Ppia (peptidylprolyl isomerase A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppia (peptidylprolyl isomerase A)
Pan paniscus (bonobo/pygmy chimpanzee) : PPIA (peptidylprolyl isomerase A)
Canis lupus familiaris (dog) : LOC403581 (peptidylprolyl isomerase A (cyclophilin A) pseudogene)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppia (peptidylprolyl isomerase A)
Sus scrofa (pig) : PPIA (peptidylprolyl isomerase A)
more info ...
Related Pseudogenes: LOC100911593  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01486,673,775 - 86,677,443 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01480,306,923 - 80,310,652 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41487,165,998 - 87,169,995 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11487,185,142 - 87,189,140 (+)NCBI
Celera1480,161,152 - 80,164,810 (+)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ppia
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3372
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.