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Gene: Rbpj (recombination signal binding protein for immunoglobulin kappa J region) Rattus norvegicus
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Symbol: Rbpj
Name: recombination signal binding protein for immunoglobulin kappa J region
Description: Predicted to have several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II repressing transcription factor binding activity; and protein N-terminus binding activity. Involved in several processes, including negative regulation of smooth muscle cell apoptotic process; negative regulation of smooth muscle cell migration; and positive regulation of smooth muscle cell proliferation. Localizes to the nucleus and protein-DNA complex. Human ortholog(s) of this gene implicated in Adams-Oliver syndrome and dilated cardiomyopathy. Orthologous to human RBPJ (recombination signal binding protein for immunoglobulin kappa J region); PARTICIPATES IN Notch signaling pathway; Notch signaling pathway; INTERACTS WITH acrylamide; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: INFERRED
Also known as: LOC679028; recombining binding protein suppressor of hairless; similar to Recombining binding protein suppressor of hairless (J kappa-recombination signal binding protein) (RBP-J kappa)
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01459,657,738 - 59,865,427 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1459,658,935 - 59,735,450 (-)Ensembl
Rnor_5.01459,785,053 - 59,859,229 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1456,447,546 - 56,510,235 (-)NCBICelera
Cytogenetic Map14q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Rbpj
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1593096
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.