Kcnip4 (potassium voltage-gated channel interacting protein 4) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Kcnip4 (potassium voltage-gated channel interacting protein 4) Rattus norvegicus
Analyze
Symbol: Kcnip4
Name: potassium voltage-gated channel interacting protein 4
RGD ID: 708539
Description: Enables potassium channel regulator activity. Involved in protein localization to plasma membrane and regulation of potassium ion transmembrane transport. Located in several cellular components, including cytosol; dendrite; and neuronal cell body. Part of voltage-gated potassium channel complex. Orthologous to human KCNIP4 (potassium voltage-gated channel interacting protein 4); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; alpha-Zearalanol; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: A-type potassium channel modulatory protein 4; Kchip4; Kv channel interacting protein 4; Kv channel-interacting protein 4; potassium channel interacting protein 4; potassium channel-interacting protein 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Kcnip4Tn(sb-T2/Bart3)2.225Mcwi  
Genetic Models: F344-Kcnip4Tn(sb-T2/Bart3)2.225Mcwi
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81465,593,297 - 66,743,994 (+)NCBIGRCr8
mRatBN7.21461,380,699 - 62,531,399 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1461,381,076 - 62,530,144 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1465,770,378 - 66,930,014 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01467,084,054 - 68,243,654 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01463,480,767 - 64,640,412 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01465,549,362 - 66,749,181 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1466,598,259 - 66,749,178 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01465,635,533 - 66,780,362 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41466,284,290 - 67,452,628 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11466,286,680 - 67,455,019 (+)NCBI
Celera1460,438,842 - 61,579,354 (+)NCBICelera
Cytogenetic Map14q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA,ISO)
cytosol  (IDA)
dendrite  (IDA)
neuronal cell body  (IDA)
peroxisome  (IEA,ISO,ISS)
plasma membrane  (IDA,IEA,ISO)
voltage-gated potassium channel complex  (IBA,IDA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Elimination of fast inactivation in Kv4 A-type potassium channels by an auxiliary subunit domain. Holmqvist MH, etal., Proc Natl Acad Sci U S A 2002 Jan 22;99(2):1035-40.
3. The stoichiometry and biophysical properties of the Kv4 potassium channel complex with K+ channel-interacting protein (KChIP) subunits are variable, depending on the relative expression level. Kitazawa M, etal., J Biol Chem. 2014 Jun 20;289(25):17597-609. doi: 10.1074/jbc.M114.563452. Epub 2014 May 8.
4. The diversity of calcium sensor proteins in the regulation of neuronal function. McCue HV, etal., Cold Spring Harb Perspect Biol. 2010 Aug;2(8):a004085. doi: 10.1101/cshperspect.a004085. Epub 2010 Jul 28.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. KChIPs and Kv4 alpha subunits as integral components of A-type potassium channels in mammalian brain. Rhodes KJ, etal., J Neurosci. 2004 Sep 8;24(36):7903-15.
10. A fundamental role for KChIPs in determining the molecular properties and trafficking of Kv4.2 potassium channels. Shibata R, etal., J Biol Chem 2003 Sep 19;278(38):36445-54. Epub 2003 Jun 26.
Additional References at PubMed
PMID:11351020   PMID:11847232   PMID:19109250   PMID:19713751   PMID:20943905   PMID:24037673   PMID:31792968  


Genomics

Comparative Map Data
Kcnip4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81465,593,297 - 66,743,994 (+)NCBIGRCr8
mRatBN7.21461,380,699 - 62,531,399 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1461,381,076 - 62,530,144 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1465,770,378 - 66,930,014 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01467,084,054 - 68,243,654 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01463,480,767 - 64,640,412 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01465,549,362 - 66,749,181 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1466,598,259 - 66,749,178 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01465,635,533 - 66,780,362 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41466,284,290 - 67,452,628 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11466,286,680 - 67,455,019 (+)NCBI
Celera1460,438,842 - 61,579,354 (+)NCBICelera
Cytogenetic Map14q11NCBI
KCNIP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38420,728,606 - 21,948,772 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl420,728,606 - 21,948,772 (-)EnsemblGRCh38hg38GRCh38
GRCh37420,730,229 - 21,950,395 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36420,339,337 - 21,559,472 (-)NCBINCBI36Build 36hg18NCBI36
Build 34420,407,313 - 21,626,643NCBI
Celera421,186,744 - 22,401,039 (-)NCBICelera
Cytogenetic Map4p15.31-p15.2NCBI
HuRef420,078,999 - 21,295,123 (-)NCBIHuRef
CHM1_1420,728,167 - 21,948,303 (-)NCBICHM1_1
T2T-CHM13v2.0420,710,285 - 21,930,631 (-)NCBIT2T-CHM13v2.0
Kcnip4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39548,546,845 - 49,682,464 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl548,546,844 - 49,682,249 (-)EnsemblGRCm39 Ensembl
GRCm38548,389,503 - 49,525,122 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl548,389,502 - 49,524,907 (-)EnsemblGRCm38mm10GRCm38
MGSCv37548,780,742 - 49,280,796 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36548,677,750 - 48,798,008 (-)NCBIMGSCv36mm8
Celera545,791,893 - 46,283,161 (-)NCBICelera
Cytogenetic Map5B3NCBI
cM Map526.26NCBI
Kcnip4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554802,803,482 - 3,909,709 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554802,803,374 - 3,911,081 (+)NCBIChiLan1.0ChiLan1.0
KCNIP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2320,977,756 - 22,200,949 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1421,174,236 - 21,742,974 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0415,131,693 - 16,354,827 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1420,422,728 - 21,645,890 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl420,422,728 - 21,645,866 (-)Ensemblpanpan1.1panPan2
KCNIP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1388,013,222 - 88,896,093 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl387,771,875 - 88,894,884 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha390,295,878 - 91,355,349 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0388,754,615 - 89,880,267 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl388,754,739 - 89,880,266 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1387,905,396 - 89,026,151 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0387,989,327 - 89,110,352 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0388,367,711 - 89,493,958 (+)NCBIUU_Cfam_GSD_1.0
Kcnip4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528553,266,229 - 54,323,681 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364776,968,085 - 8,028,852 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364776,967,927 - 8,024,539 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNIP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl815,211,917 - 16,346,786 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1815,211,916 - 16,346,358 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2815,470,139 - 16,695,141 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KCNIP4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12728,350,918 - 29,539,229 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2729,420,010 - 29,541,783 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604774,924,974 - 76,156,301 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnip4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475510,271,283 - 11,391,984 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475510,271,131 - 11,392,421 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Kcnip4
6640 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:106
Count of miRNA genes:87
Interacting mature miRNAs:92
Transcripts:ENSRNOT00000049743
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141854133263541332Rat
10755459Coatc15Coat color QTL 150.01681coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)141983694464836944Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
1300154Bp189Blood pressure QTL 1893.04arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)143088377768757901Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143766971982669719Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143766971982669719Rat
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143905723783368335Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143999825175582726Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)145002321195023211Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1455624247100624247Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1456631369101631369Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat

Markers in Region
D14Rat87  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21462,352,815 - 62,353,037 (+)MAPPERmRatBN7.2
Rnor_6.01466,574,929 - 66,575,150NCBIRnor6.0
Rnor_5.01466,605,954 - 66,606,175UniSTSRnor5.0
RGSC_v3.41467,261,866 - 67,262,088RGDRGSC3.4
RGSC_v3.41467,261,867 - 67,262,088UniSTSRGSC3.4
RGSC_v3.11467,264,257 - 67,264,479RGD
Celera1461,407,771 - 61,407,992UniSTS
SHRSP x BN Map1430.5RGD
SHRSP x BN Map1430.5UniSTS
Cytogenetic Map14q11UniSTS
D14Rat88  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01465,964,437 - 65,964,586UniSTSRnor5.0
Rnor_5.01465,509,916 - 65,510,065UniSTSRnor5.0
RGSC_v3.41466,611,911 - 66,612,061RGDRGSC3.4
RGSC_v3.41466,611,912 - 66,612,061UniSTSRGSC3.4
RGSC_v3.11466,614,302 - 66,614,452RGD
Celera1460,765,356 - 60,765,505UniSTS
SHRSP x BN Map1430.5UniSTS
SHRSP x BN Map1430.5RGD
Cytogenetic Map14q11UniSTS
D14Got108  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21461,512,901 - 61,513,087 (+)MAPPERmRatBN7.2
Rnor_6.01465,681,578 - 65,681,761NCBIRnor6.0
Rnor_5.01465,767,745 - 65,767,928UniSTSRnor5.0
RGSC_v3.41466,417,132 - 66,417,315UniSTSRGSC3.4
Celera1460,571,074 - 60,571,263UniSTS
Cytogenetic Map14q11UniSTS
D14Got137  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21461,686,564 - 61,686,856 (+)MAPPERmRatBN7.2
Rnor_6.01465,856,874 - 65,857,165NCBIRnor6.0
Rnor_6.01465,403,962 - 65,404,253NCBIRnor6.0
Rnor_5.01465,488,798 - 65,489,089UniSTSRnor5.0
Rnor_5.01465,943,053 - 65,943,344UniSTSRnor5.0
RGSC_v3.41466,590,794 - 66,591,085UniSTSRGSC3.4
Celera1460,744,373 - 60,744,660UniSTS
Cytogenetic Map14q11UniSTS
D14Got104  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21462,145,316 - 62,145,449 (+)MAPPERmRatBN7.2
Rnor_6.01466,367,581 - 66,367,713NCBIRnor6.0
Rnor_5.01466,399,806 - 66,399,938UniSTSRnor5.0
RGSC_v3.41467,051,447 - 67,051,579UniSTSRGSC3.4
Celera1461,201,010 - 61,201,142UniSTS
Cytogenetic Map14q11UniSTS
RH131556  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21461,402,119 - 61,402,300 (+)MAPPERmRatBN7.2
Rnor_6.01465,570,787 - 65,570,967NCBIRnor6.0
Rnor_5.01465,656,954 - 65,657,134UniSTSRnor5.0
RGSC_v3.41466,306,333 - 66,306,513UniSTSRGSC3.4
Celera1460,460,257 - 60,460,437UniSTS
RH 3.4 Map14480.58UniSTS
Cytogenetic Map14q11UniSTS
RH144553  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21461,675,285 - 61,675,437 (+)MAPPERmRatBN7.2
Rnor_6.01465,845,595 - 65,845,746NCBIRnor6.0
Rnor_6.01465,392,681 - 65,392,832NCBIRnor6.0
Rnor_5.01465,931,774 - 65,931,925UniSTSRnor5.0
Rnor_5.01465,477,517 - 65,477,668UniSTSRnor5.0
RGSC_v3.41466,579,513 - 66,579,664UniSTSRGSC3.4
Celera1460,733,095 - 60,733,246UniSTS
RH 3.4 Map14458.87UniSTS
Cytogenetic Map14q11UniSTS
BE113856  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21461,417,571 - 61,417,770 (+)MAPPERmRatBN7.2
Rnor_6.01465,586,235 - 65,586,433NCBIRnor6.0
Rnor_5.01465,672,402 - 65,672,600UniSTSRnor5.0
RGSC_v3.41466,321,781 - 66,321,979UniSTSRGSC3.4
Celera1460,475,725 - 60,475,923UniSTS
RH 3.4 Map14479.58UniSTS
Cytogenetic Map14q11UniSTS
BE114195  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21461,810,376 - 61,810,526 (+)MAPPERmRatBN7.2
Rnor_6.01466,032,768 - 66,032,917NCBIRnor6.0
Rnor_5.01466,065,578 - 66,065,727UniSTSRnor5.0
RGSC_v3.41466,714,514 - 66,714,663UniSTSRGSC3.4
Celera1460,867,776 - 60,867,925UniSTS
RH 3.4 Map14455.07UniSTS
Cytogenetic Map14q11UniSTS
RH137736  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21461,949,228 - 61,949,385 (+)MAPPERmRatBN7.2
Rnor_6.01466,171,622 - 66,171,778NCBIRnor6.0
Rnor_5.01466,204,382 - 66,204,538UniSTSRnor5.0
RGSC_v3.41466,854,594 - 66,854,750UniSTSRGSC3.4
Celera1461,006,353 - 61,006,509UniSTS
RH 3.4 Map14455.27UniSTS
Cytogenetic Map14q11UniSTS
RH138036  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21462,001,081 - 62,001,306 (+)MAPPERmRatBN7.2
Rnor_6.01466,222,692 - 66,222,916NCBIRnor6.0
Rnor_5.01466,255,437 - 66,255,661UniSTSRnor5.0
RGSC_v3.41466,907,398 - 66,907,622UniSTSRGSC3.4
Celera1461,058,082 - 61,058,306UniSTS
RH 3.4 Map14456.97UniSTS
Cytogenetic Map14q11UniSTS
RH138347  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21461,400,768 - 61,401,015 (+)MAPPERmRatBN7.2
mRatBN7.2124,600,956 - 24,601,203 (+)MAPPERmRatBN7.2
Rnor_6.0185,612,206 - 85,612,452NCBIRnor6.0
Rnor_6.01465,569,436 - 65,569,682NCBIRnor6.0
Rnor_5.01465,655,603 - 65,655,849UniSTSRnor5.0
Rnor_5.0186,822,307 - 86,822,553UniSTSRnor5.0
RGSC_v3.4125,174,427 - 25,174,673UniSTSRGSC3.4
RGSC_v3.41466,304,982 - 66,305,228UniSTSRGSC3.4
Celera1460,458,906 - 60,459,152UniSTS
Celera123,297,501 - 23,297,747UniSTS
Cytogenetic Map14q11UniSTS
BE115263  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21461,668,599 - 61,668,759 (+)MAPPERmRatBN7.2
Rnor_6.01465,838,914 - 65,839,073NCBIRnor6.0
Rnor_6.01465,385,997 - 65,386,156NCBIRnor6.0
Rnor_5.01465,925,093 - 65,925,252UniSTSRnor5.0
Rnor_5.01465,470,833 - 65,470,992UniSTSRnor5.0
RGSC_v3.41466,572,829 - 66,572,988UniSTSRGSC3.4
Celera1460,726,412 - 60,726,571UniSTS
RH 3.4 Map14475.3UniSTS
Cytogenetic Map14q11UniSTS


Genetic Models
This gene Kcnip4 is modified in the following models/strains:


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 42 12 4
Low 2 20 7 4 2 4 6 6 32 23 28 10 6
Below cutoff 1 22 38 25 13 25 2 3 7 1 2

Sequence


RefSeq Acc Id: ENSRNOT00000049743   ⟹   ENSRNOP00000042016
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1461,381,076 - 62,530,144 (+)Ensembl
Rnor_6.0 Ensembl1466,598,259 - 66,747,764 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000079658   ⟹   ENSRNOP00000075583
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1461,381,076 - 62,530,144 (+)Ensembl
Rnor_6.0 Ensembl1466,631,690 - 66,749,178 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000114580   ⟹   ENSRNOP00000089378
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1462,001,932 - 62,530,144 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000115304   ⟹   ENSRNOP00000086123
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1462,376,019 - 62,530,144 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000115977   ⟹   ENSRNOP00000079125
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1461,622,729 - 62,530,144 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000118278   ⟹   ENSRNOP00000081482
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1462,291,120 - 62,530,144 (+)Ensembl
RefSeq Acc Id: NM_181365   ⟹   NP_852030
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81465,593,297 - 66,742,739 (+)NCBI
mRatBN7.21461,380,699 - 62,530,144 (+)NCBI
Rnor_6.01465,549,366 - 66,747,926 (+)NCBI
Rnor_5.01465,635,533 - 66,780,362 (+)NCBI
RGSC_v3.41466,284,290 - 67,452,628 (+)RGD
Celera1460,438,842 - 61,579,354 (+)RGD
Sequence:
RefSeq Acc Id: XM_017599086   ⟹   XP_017454575
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81466,486,590 - 66,743,994 (+)NCBI
mRatBN7.21462,291,156 - 62,531,399 (+)NCBI
Rnor_6.01466,512,739 - 66,749,181 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017599087   ⟹   XP_017454576
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81466,184,943 - 66,743,994 (+)NCBI
mRatBN7.21462,001,895 - 62,531,399 (+)NCBI
Rnor_6.01466,224,703 - 66,749,181 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017599088   ⟹   XP_017454577
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81465,778,977 - 66,743,994 (+)NCBI
mRatBN7.21461,617,718 - 62,531,399 (+)NCBI
Rnor_6.01465,789,433 - 66,749,181 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017599089   ⟹   XP_017454578
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81465,593,343 - 66,743,994 (+)NCBI
mRatBN7.21461,380,758 - 62,531,399 (+)NCBI
Rnor_6.01465,549,362 - 66,749,181 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063272886   ⟹   XP_063128956
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81465,593,302 - 66,743,994 (+)NCBI
RefSeq Acc Id: XM_063272887   ⟹   XP_063128957
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81466,486,600 - 66,743,994 (+)NCBI
RefSeq Acc Id: NP_852030   ⟸   NM_181365
- UniProtKB: Q99MG8 (UniProtKB/Swiss-Prot),   Q99MG9 (UniProtKB/Swiss-Prot),   G3V9C1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454578   ⟸   XM_017599089
- Peptide Label: isoform X5
- UniProtKB: G3V9C1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454577   ⟸   XM_017599088
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZMG1 (UniProtKB/TrEMBL),   G3V9C1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454576   ⟸   XM_017599087
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A8J8 (UniProtKB/TrEMBL),   G3V9C1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454575   ⟸   XM_017599086
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZSB5 (UniProtKB/TrEMBL),   G3V9C1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000075583   ⟸   ENSRNOT00000079658
RefSeq Acc Id: ENSRNOP00000042016   ⟸   ENSRNOT00000049743
RefSeq Acc Id: ENSRNOP00000089378   ⟸   ENSRNOT00000114580
RefSeq Acc Id: ENSRNOP00000081482   ⟸   ENSRNOT00000118278
RefSeq Acc Id: ENSRNOP00000086123   ⟸   ENSRNOT00000115304
RefSeq Acc Id: ENSRNOP00000079125   ⟸   ENSRNOT00000115977
RefSeq Acc Id: XP_063128956   ⟸   XM_063272886
- Peptide Label: isoform X1
- UniProtKB: G3V9C1 (UniProtKB/TrEMBL),   A6IJJ6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128957   ⟸   XM_063272887
- Peptide Label: isoform X6
- UniProtKB: G3V9C1 (UniProtKB/TrEMBL),   A0A0G2KAZ2 (UniProtKB/TrEMBL),   A6IJJ8 (UniProtKB/TrEMBL)
Protein Domains
EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99MG9-F1-model_v2 AlphaFold Q99MG9 1-250 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708539 AgrOrtholog
BioCyc Gene G2FUF-15572 BioCyc
Ensembl Genes ENSRNOG00000032350 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055011370 UniProtKB/Swiss-Prot
  ENSRNOG00060016461 UniProtKB/Swiss-Prot
  ENSRNOG00065005509 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000049743 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000049743.5 UniProtKB/Swiss-Prot
  ENSRNOT00000079658 UniProtKB/TrEMBL
  ENSRNOT00000079658.2 UniProtKB/Swiss-Prot
  ENSRNOT00000114580.1 UniProtKB/TrEMBL
  ENSRNOT00000115304.1 UniProtKB/TrEMBL
  ENSRNOT00000115977.1 UniProtKB/TrEMBL
  ENSRNOT00000118278.1 UniProtKB/TrEMBL
  ENSRNOT00055019329 UniProtKB/Swiss-Prot
  ENSRNOT00060028331 UniProtKB/Swiss-Prot
  ENSRNOT00065008188 UniProtKB/Swiss-Prot
Gene3D-CATH EF-hand UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Recoverin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:259243 UniProtKB/Swiss-Prot
NCBI Gene 259243 ENTREZGENE
PANTHER KV CHANNEL-INTERACTING PROTEIN 4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR23055 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam EF-hand_7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Kcnip4 PhenoGen
PRINTS RECOVERIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000032350 RatGTEx
  ENSRNOG00055011370 RatGTEx
  ENSRNOG00060016461 RatGTEx
  ENSRNOG00065005509 RatGTEx
SMART EFh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2KAZ2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZMG1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZSB5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A325_RAT UniProtKB/TrEMBL
  A0A8I6A8J8 ENTREZGENE, UniProtKB/TrEMBL
  A6IJJ6 ENTREZGENE, UniProtKB/TrEMBL
  A6IJJ8 ENTREZGENE, UniProtKB/TrEMBL
  G3V9C1 ENTREZGENE, UniProtKB/TrEMBL
  KCIP4_RAT UniProtKB/Swiss-Prot
  Q99MG8 ENTREZGENE
  Q99MG9 ENTREZGENE
UniProt Secondary Q99MG8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Kcnip4  Kv channel interacting protein 4    potassium channel interacting protein 4  Name updated 1299863 APPROVED
2004-09-10 Kcnip4  potassium channel interacting protein 4  Kchip4    Symbol and Name updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference