Alcrsp11 QTL Report (Rattus norvegicus) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: Alcrsp11 (Alcohol response QTL 11) Rattus norvegicus

Symbol: Alcrsp11
Name: Alcohol response QTL 11
RGD ID: 1641900
Previously known as: Blood ethanol concentration 1; BEC1
Trait: alcohol metabolism trait   (VT:0015089)    
Measurement Type: blood ethanol level   (CMO:0000535)    
LOD Score: Likelihood Ratio: 11.3
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81474,255,551 - 109,089,856RGD_MAPPER_PIPELINE
mRatBN7.21470,053,989 - 104,886,043RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01480,049,285 - 115,493,446RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01479,794,074 - 115,151,701RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41476,579,917 - 112,194,335RGD_MAPPER_PIPELINERGSC3.4
RGSC_v3.11476,599,062 - 112,220,682RGD
Cross Type: intercross
Strains Crossed: LAS1 HAS1 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alcrsp11Ratalcohol-induced mental disorder susceptibilityIDA 1334439 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alcrsp11Ratalcohol preference  IDA 1334439 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alcrsp11Ratblood ethanol level  IDA 1334439 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alcrsp11Ratcontrol condition  IDA 1334439 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alcrsp11Ratspectrophotometry  IDA 1334439 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alcrsp11RatHAS1  IEA 1334439 RGD 
Alcrsp11RatLAS1  IEA 1334439 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alcrsp11Ratalcohol metabolism trait  IDA 1334439 RGD 


#
Reference Title
Reference Citation
1. Quantitative trait Loci mapping for ethanol sensitivity and neurotensin receptor density in an F2 intercross derived from inbred high and low alcohol sensitivity selectively bred rat lines. Radcliffe RA, etal., Alcohol Clin Exp Res 2004 Dec;28(12):1796-804.
2. Confirmation of quantitative trait loci for ethanol sensitivity and neurotensin receptor density in crosses derived from the inbred high and low alcohol sensitive selectively bred rat lines. Radcliffe RA, etal., Psychopharmacology (Berl). 2006 Oct;188(3):343-54. Epub 2006 Sep 5.


1 to 20 of 476 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
41049027LOC120096798small nucleolar RNA SNORA48147072567770725820Rat
41375811LOC120096628uncharacterized LOC120096628147075478670773614Rat
41026202LOC120096742U6 spliceosomal RNA147110536771105473Rat
71084Hs3st1heparan sulfate-glucosamine 3-sulfotransferase 1147118582671223263Rat
40982593LOC120096805small nucleolar RNA SNORA17147128817071288300Rat
7582281LOC102547538uncharacterized LOC102547538147141470071436779Rat
41216753LOC120096629uncharacterized LOC120096629147141654271450253Rat
41037518LOC120096630uncharacterized LOC120096630147147693571491085Rat
7628136LOC102547760uncharacterized LOC102547760147153081571543942Rat
11468209LOC108352769uncharacterized LOC108352769147160525971619000Rat
41376686LOC120096631uncharacterized LOC120096631147189142671918318Rat
1562417Clnkcytokine-dependent hematopoietic cell linker147192389472101180Rat
41091094LOC120096873U6 spliceosomal RNA147198380671983907Rat
41114651LOC120096632uncharacterized LOC120096632147206246772124747Rat
41336455LOC120096758U6 spliceosomal RNA147210890772109011Rat
1564150Zfp518bzinc finger protein 518B147212108572140479Rat
1593174Nono-ps12non-POU domain containing, octamer-binding, pseudogene 12147214458972154945Rat
1598288Rrm1-ps1ribonucleotide reductase M1, pseudogene 1147217738672180323Rat
11478553LOC108352833serine/arginine-rich splicing factor 3 pseudogene147218261672183963Rat
1305789Wdr1WD repeat domain 1147225803272291768Rat

1 to 20 of 476 rows
1 to 20 of 637 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
43024D14Rat125346147020676770207113Ratregion
7206206Hs3st1205147121520671215411Ratregion
5065142AA963021219147121592471216143Ratregion
5036227D5Wsu110e224147121613671216360Ratregion
5081142RH141989195147121683771217032Ratregion
5089945AU049457225147122902571229250Ratregion
5088353AU048518174147145644071456614Ratregion
60072D14Got60284147192858171928866Ratregion
60072D14Got60284147192861371928866Ratregion
43025D14Rat126285147192890771929192Ratregion
5030309BF402166152147208207372082225Ratregion
5029661BF386746162147212151772121679Ratregion
5041874RH129109151147214025272140403Ratregion
5060112BI279462173147217980472179977Ratregion
5506624SFRS3_1875612147218383672184468Ratregion
5052987RH142389579147229092072291499Ratregion
5040262RH128182195147229149072291685Ratregion
5056137RH144204171147248822572488396Ratregion
62438D14Uia1100147248920472489304Ratregion
1627189D14Mco14196147248920572489400Ratregion
1 to 20 of 637 rows

Peak: (D14Rat38)
Rat AssemblyChrPosition (strand)Source
GRCr81496,755,448 - 96,755,654 (+)Marker Load Pipeline
mRatBN7.21492,553,886 - 92,554,092 (+)MAPPER
Rnor_6.014102,549,183 - 102,549,388NCBI
Rnor_5.014102,293,972 - 102,294,177UniSTS
RGSC_v3.41499,079,814 - 99,080,020RGD
RGSC_v3.41499,079,815 - 99,080,020UniSTS
RGSC_v3.11499,098,960 - 99,099,165RGD
Celera1491,586,511 - 91,586,716UniSTS
RH 3.4 Map14705.3RGD
RH 3.4 Map14705.3UniSTS
SHRSP x BN Map1463.96UniSTS
SHRSP x BN Map1463.96RGD


1 to 10 of 27 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143999825175582726Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)146875779683368335Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1456631369101631369Rat
4889951Bss92Bone structure and strength QTL 923.9tibia area (VT:1000281)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)148205747195876975Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat

1 to 10 of 27 rows


Note Type Note Reference
qtl_cross_type intercross  
qtl_general measurement method: spectrophotometric enzyme assay was done to determine the blood ethanol concentration 1334439
qtl_general number of animals used: 70 days old 363 F2 rats, inducing agent: intraperitoneal administration of alcohol 3.5 g/kg 1334439
qtl_general software package used: Map Manager QTX 1334439
qtl_statistics Likelihood Ratio: 11.3 1334439