Erlec1 (endoplasmic reticulum lectin 1)

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Gene: Erlec1 (endoplasmic reticulum lectin 1) Rattus norvegicus

Analyze

Symbol:

Erlec1

Name:

endoplasmic reticulum lectin 1

RGD ID:

1306508

Description:

Predicted to enable unfolded protein binding activity. Predicted to be involved in negative regulation of retrograde protein transport, ER to cytosol; retrograde protein transport, ER to cytosol; and ubiquitin-dependent ERAD pathway. Predicted to be active in endoplasmic reticulum lumen. Orthologous to human ERLEC1 (endoplasmic reticulum lectin 1); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; acrylamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC289874; RGD1306508; similar to hypothetical protein CL25084

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ERLEC1 (endoplasmic reticulum lectin 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Erlec1 (endoplasmic reticulum lectin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Erlec1 (endoplasmic reticulum lectin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ERLEC1 (endoplasmic reticulum lectin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ERLEC1 (endoplasmic reticulum lectin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Erlec1 (endoplasmic reticulum lectin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ERLEC1 (endoplasmic reticulum lectin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ERLEC1 (endoplasmic reticulum lectin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Erlec1 (endoplasmic reticulum lectin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	MPZ (myelin protein zero)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	ERLEC1 (endoplasmic reticulum lectin 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Erlec1 (endoplasmic reticulum lectin 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	erlec1 (endoplasmic reticulum lectin 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	YOS9	Alliance	DIOPT (OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	Y105E8A.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG6766	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	cadm1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	erlec1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	14	104,655,745 - 104,693,508 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	104,655,673 - 104,693,480 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	108,967,766 - 109,005,451 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	110,194,745 - 110,232,411 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	106,667,186 - 106,704,842 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	115,314,890 - 115,352,871 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	115,314,890 - 115,352,562 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	114,972,393 - 115,009,275 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	112,046,496 - 112,086,271 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	112,072,200 - 112,112,551 (-)	NCBI
Celera	14	103,493,416 - 103,531,051 (-)	NCBI		Celera
Cytogenetic Map	14	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Chemical and Drug Induced Liver Injury (ISO)

cholestasis (ISO)

genetic disease (ISO)

Malocclusion, Angle Class III (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-hydroxypropanoic acid (ISO)

3-chloropropane-1,2-diol (EXP)

acrolein (ISO)

acrylamide (EXP)

alpha-pinene (ISO)

aristolochic acid A (ISO)

benzo[a]pyrene diol epoxide I (ISO)

Benzo[ghi]perylene (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (EXP)

carbon nanotube (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

endosulfan (EXP)

fenthion (ISO)

folic acid (ISO)

hydralazine (ISO)

ivermectin (ISO)

methidathion (ISO)

ozone (ISO)

phenobarbital (ISO)

potassium chromate (ISO)

rac-lactic acid (ISO)

sodium arsenate (ISO)

thioacetamide (EXP)

troglitazone (ISO)

tunicamycin (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

endoplasmic reticulum unfolded protein response (IEA)

negative regulation of retrograde protein transport, ER to cytosol (ISO)

retrograde protein transport, ER to cytosol (IBA)

ubiquitin-dependent ERAD pathway (IBA,ISO)

Cellular Component

endoplasmic reticulum lumen (IBA,ISO)

Molecular Function

carbohydrate binding (IEA)

protein binding (ISO)

unfolded protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

Endoplasmic Reticulum-associated degradation pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:16531414	PMID:18264092	PMID:18502753	PMID:21062743	PMID:25660456

Genomics

Comparative Map Data

Erlec1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	14	104,655,745 - 104,693,508 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	104,655,673 - 104,693,480 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	108,967,766 - 109,005,451 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	110,194,745 - 110,232,411 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	106,667,186 - 106,704,842 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	115,314,890 - 115,352,871 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	115,314,890 - 115,352,562 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	114,972,393 - 115,009,275 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	112,046,496 - 112,086,271 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	112,072,200 - 112,112,551 (-)	NCBI
Celera	14	103,493,416 - 103,531,051 (-)	NCBI		Celera
Cytogenetic Map	14	q22	NCBI

ERLEC1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	53,787,044 - 53,818,796 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	53,787,009 - 53,833,038 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	54,014,181 - 54,045,933 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	53,867,721 - 53,899,437 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	53,925,867 - 53,957,584	NCBI
Celera	2	53,854,922 - 53,887,349 (+)	NCBI		Celera
Cytogenetic Map	2	p16.2	NCBI
HuRef	2	53,748,407 - 53,780,295 (+)	NCBI		HuRef
CHM1_1	2	53,945,053 - 53,976,959 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	53,783,247 - 53,814,984 (+)	NCBI		T2T-CHM13v2.0

Erlec1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	30,812,794 - 30,904,385 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	30,880,774 - 30,904,335 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	30,862,794 - 30,954,386 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	30,930,774 - 30,954,335 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	30,829,784 - 30,854,131 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	30,831,419 - 30,854,123 (-)	NCBI		MGSCv36	mm8
Celera	11	33,335,160 - 33,359,441 (-)	NCBI		Celera
Cytogenetic Map	11	A4	NCBI
cM Map	11	18.18	NCBI

Erlec1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955441	19,535,425 - 19,557,458 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955441	19,535,425 - 19,557,960 (+)	NCBI	ChiLan1.0	ChiLan1.0

ERLEC1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	2A	72,543,487 - 72,575,091 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	53,930,280 - 53,962,178 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	54,842,228 - 54,874,068 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	54,842,228 - 54,874,068 (+)	Ensembl	panpan1.1		panPan2

ERLEC1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	54,815,592 - 54,845,776 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	54,815,638 - 54,845,080 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	54,767,465 - 54,797,664 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	55,814,249 - 55,845,028 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	55,814,274 - 55,845,027 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	55,507,493 - 55,537,678 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	55,793,731 - 55,824,185 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	56,080,596 - 56,110,787 (+)	NCBI		UU_Cfam_GSD_1.0

Erlec1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	28,193,321 - 28,219,474 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936491	351,420 - 378,441 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936491	351,813 - 377,978 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ERLEC1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	87,355,904 - 87,389,814 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	87,362,166 - 87,389,814 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	92,521,490 - 92,549,096 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ERLEC1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	53,150,627 - 53,188,821 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	53,154,556 - 53,188,538 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666045	58,516,256 - 58,554,383 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Erlec1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624833	7,964,810 - 7,992,582 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624833	7,964,815 - 7,992,277 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Erlec1
202 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	303
Count of miRNA genes:	186
Interacting mature miRNAs:	208
Transcripts:	ENSRNOT00000050321
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1582259	Gluco23	Glucose level QTL 23	3.1	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	70053989	104886043	Rat
1641900	Alcrsp11	Alcohol response QTL 11			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	14	70053989	104886043	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	19	41	8	11	74	35	41	11	8
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106023	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006251615	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091779	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005492923	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC166988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473996	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ228963	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232613	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000254	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000050321 ⟹ ENSRNOP00000043115

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	104,655,673 - 104,693,480 (-)	Ensembl
Rnor_6.0 Ensembl	14	115,314,890 - 115,352,562 (-)	Ensembl

RefSeq Acc Id:

NM_001106023 ⟹ NP_001099493

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	104,655,745 - 104,693,383 (-)	NCBI
Rnor_6.0	14	115,314,890 - 115,352,562 (-)	NCBI
Rnor_5.0	14	114,972,393 - 115,009,275 (-)	NCBI
RGSC_v3.4	14	112,046,496 - 112,086,271 (-)	RGD
Celera	14	103,493,416 - 103,531,051 (-)	RGD

Sequence:

show sequence

TCCTCCTCCTCCTCCACCTGTTCTCCTCGGGTAGAGGAGGTTGTGACGGCGGCTGGAGGACGCG
GCGATGGAGGAAGGAGGCGGCGGCTTGCGGAGCCTGGTCCCCGGAGGGCCGCTGTTGCTGGTTC
TGTACGGTCTCCTGGAGGCGGCCGCCGGCGGCCGAGCGCTGCCCCAGCTCAGCGACGACATCCC
CTTCCGAGTCAACTGGCCCGGCACCGAGTTCTCTCTGCCTACAACTGGAGTTTTGTATAAAGAA
GATAATTACATCATCATGACAACTGCACATAAAGAAAAATACAAATGTATACTTCCGCTTGTGA
CAAGTGGGGATGAGGAAGAAGAAAAGGATTACAAAGGCCCCAATCCAAGAGAGCTTTTGGAACC
ACTATTTAAACAGAGCAGTTGTTCCTACAGAATTGAGTCTTACTGGACTTATGAAGTATGTCAT
GGGAAACATATTCGACAGTACCATGAAGAAAAAGAAACTGGCCAAAAAGTAAATATTCACGAAT
ACTACCTTGGGAATATGTTGGCTAAGAGTCTTCTGTATGAAAAAGAACAAGCAAAAGAAAAAGA
GAAGTCAAATGAGATTCCCACTAAAAACATTGAAGGTCAGATGACACCCTACTATCCTGTGGGA
ATGGGAAATGGTACACCTTGTAGTCTGAAACAAAATCGACCCAGATCAAGTACTGTGATGTACA
TATGCCATCCTGAGTCTAAGCATGAAATCCTTTCAGTAGCTGAAGTTACAACTTGTGAATATGA
AGTTGTCATTTTGACACCACTCTTGTGCAGCCATCCTAAGTACAAGTTCAGAGCCTCTCCTGTG
AATGACATATTCTGTCAATCACTGCCGGGATCTCCATTTAAACCCCTCACTCTAAGACAGTTGG
AGCAACAGGAAGAGATACTGAGGGTGCCATTTAGGAGAAATAAAGAGGAAGATTTGTCATCTGC
TAAAGAAGAGAGATTTCCAGCCATTCACAAACCTATTGCTGTTGGCTCTCAGCCAGTGCTCACT
GTTGGAACAACCCACATTTCCAAGCTGACAGATGACCAGCTCATAAAGGAGTTCCTAAGTGGTT
CTTACTGCTTTCATGGGGGTGTTGGTTGGTGGAAATATGAATTCTGCTATGGCAAGCATGTACA
TCAGTATCATGAGGACAAAGATAATGGGAAAACTTCTGTAGTTGTGGGGACATGGAACCAAGAA
GAGCATGTTGAGTGGGCTAAGAAAAACACTGCTAGAGCTTATCATCTTCAAGACGATGGCACCC
AGACAGTCAGGATGGTGTCACATTTTTATGGAAATGGGGATATTTGTGATATAACTGACAAACC
CAGACAGGTGACTGTAAAACTAAAGTGTAAAGAATCAGATTCTCCTCATGCTGTTACTGTATAT
ATGCTTGAGCCTCACTCCTGCCAGTATATTCTTGGGGTTGAATCTCCAGTAATCTGTAAAATTC
TAGATACAGCTGATGAAAATGGACTTCTTTCTCTCCCCAATTAAAGGATATTAAACTTGAAGGA
AAGAAAGATGATTGAAAATCATCACTTCCTCCTGACCACATCTCATTGTAGAGTCTCACCATTG
GACCTTGTCTATAGCATTCACAAAAAAGGACTGGCAACCACACTGTGAAATTCATGTGTATATA
AGAGATTATGGATAAACTTATAAGGCAGATCCTTGTCTCACTTCATTCATTTTGGTCTTGTATG
AACTGATTGTGTTTGGCTTTGCTTGGGTAATGTAATTTCAAAACAAATCTGGTCTAAGCACTTT
AGTTCAGCCTATCAAATGTCATAATTCTTGTAGTTTTAAGTATTTTAAATAATATACTTACTGA
ATAAATTATAGCATATAT

hide sequence

RefSeq Acc Id:

XM_039091779 ⟹ XP_038947707

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	104,655,926 - 104,693,490 (-)	NCBI

RefSeq Acc Id:

XR_005492923

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	104,655,926 - 104,693,508 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001099493	(Get FASTA)	NCBI Sequence Viewer
	XP_038947707	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI66988	(Get FASTA)	NCBI Sequence Viewer
	EDL98050	(Get FASTA)	NCBI Sequence Viewer
	EDL98051	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000043115
	ENSRNOP00000043115.4

RefSeq Acc Id:	NP_001099493 ⟸ NM_001106023
- Peptide Label:	precursor
- UniProtKB:	D3ZF97 (UniProtKB/TrEMBL), A6JQD3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEEGGGGLRSLVPGGPLLLVLYGLLEAAAGGRALPQLSDDIPFRVNWPGTEFSLPTTGVLYKED NYIIMTTAHKEKYKCILPLVTSGDEEEEKDYKGPNPRELLEPLFKQSSCSYRIESYWTYEVCHG KHIRQYHEEKETGQKVNIHEYYLGNMLAKSLLYEKEQAKEKEKSNEIPTKNIEGQMTPYYPVGM GNGTPCSLKQNRPRSSTVMYICHPESKHEILSVAEVTTCEYEVVILTPLLCSHPKYKFRASPVN DIFCQSLPGSPFKPLTLRQLEQQEEILRVPFRRNKEEDLSSAKEERFPAIHKPIAVGSQPVLTV GTTHISKLTDDQLIKEFLSGSYCFHGGVGWWKYEFCYGKHVHQYHEDKDNGKTSVVVGTWNQEE HVEWAKKNTARAYHLQDDGTQTVRMVSHFYGNGDICDITDKPRQVTVKLKCKESDSPHAVTVYM LEPHSCQYILGVESPVICKILDTADENGLLSLPN hide sequence

RefSeq Acc Id:

ENSRNOP00000043115 ⟸ ENSRNOT00000050321

RefSeq Acc Id:	XP_038947707 ⟸ XM_039091779
- Peptide Label:	isoform X1

Protein Domains

MRH

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZF97-F1-model_v2	AlphaFold	D3ZF97	1-482	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699541

Promoter ID:

EPDNEW_R10065

Type:

multiple initiation site

Name:

Erlec1_1

Description:

endoplasmic reticulum lectin 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	14	115,352,645 - 115,352,705	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306508	AgrOrtholog
BioCyc Gene	G2FUF-14626	BioCyc
Ensembl Genes	ENSRNOG00000007283	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000050321	ENTREZGENE
	ENSRNOT00000050321.5	UniProtKB/TrEMBL
Gene3D-CATH	2.70.130.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7303938	IMAGE-MGC_LOAD
InterPro	Man6P_isomerase_rcpt-bd_dom	UniProtKB/TrEMBL
	MRH_dom	UniProtKB/TrEMBL
	OS-9-like	UniProtKB/TrEMBL
	PRKCSH	UniProtKB/TrEMBL
KEGG Report	rno:289874	UniProtKB/TrEMBL
MGC_CLONE	MGC:189119	IMAGE-MGC_LOAD
NCBI Gene	289874	ENTREZGENE
PANTHER	ENDOPLASMIC RETICULUM LECTIN 1	UniProtKB/TrEMBL
	PTHR15414	UniProtKB/TrEMBL
Pfam	PRKCSH	UniProtKB/TrEMBL
PhenoGen	Erlec1	PhenoGen
PROSITE	MRH	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000007283	RatGTEx
Superfamily-SCOP	SSF50911	UniProtKB/TrEMBL
UniProt	A6JQD3	ENTREZGENE, UniProtKB/TrEMBL
	D3ZF97	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2010-02-12	Erlec1	endoplasmic reticulum lectin 1	RGD1306508	similar to hypothetical protein CL25084	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1306508	similar to hypothetical protein CL25084	RGD1306508_predicted	similar to hypothetical protein CL25084 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-20	RGD1306508_predicted	similar to hypothetical protein CL25084 (predicted)	LOC289874_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC289874_predicted	similar to hypothetical protein CL25084 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)