Cpz (carboxypeptidase Z) - Rat Genome Database

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Gene: Cpz (carboxypeptidase Z) Rattus norvegicus
Analyze
Symbol: Cpz
Name: carboxypeptidase Z
RGD ID: 620496
Description: Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in peptide metabolic process and protein processing. Predicted to be active in extracellular space. Orthologous to human CPZ (carboxypeptidase Z); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21475,223,692 - 75,246,946 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1475,223,605 - 75,246,945 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1479,677,279 - 79,700,523 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01480,918,147 - 80,941,395 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01477,363,131 - 77,386,387 (+)NCBIRnor_WKY
Rnor_6.01480,402,946 - 80,426,203 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1480,403,001 - 80,426,245 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01480,028,890 - 80,052,296 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41480,857,371 - 80,880,592 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11480,859,761 - 80,882,982 (+)NCBI
Celera1474,152,116 - 74,175,339 (+)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Dwarfism  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. Metallocarboxypeptidase Z is dynamically expressed in mouse development. Novikova E, etal., Mech Dev 2001 Apr;102(1-2):259-62.
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9570147   PMID:10671522   PMID:12419858   PMID:18847325   PMID:23376485  


Genomics

Comparative Map Data
Cpz
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21475,223,692 - 75,246,946 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1475,223,605 - 75,246,945 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1479,677,279 - 79,700,523 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01480,918,147 - 80,941,395 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01477,363,131 - 77,386,387 (+)NCBIRnor_WKY
Rnor_6.01480,402,946 - 80,426,203 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1480,403,001 - 80,426,245 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01480,028,890 - 80,052,296 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41480,857,371 - 80,880,592 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11480,859,761 - 80,882,982 (+)NCBI
Celera1474,152,116 - 74,175,339 (+)NCBICelera
Cytogenetic Map14q21NCBI
CPZ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3848,592,765 - 8,619,752 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl48,592,660 - 8,619,759 (+)EnsemblGRCh38hg38GRCh38
GRCh3748,594,492 - 8,621,479 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3648,645,335 - 8,672,388 (+)NCBINCBI36Build 36hg18NCBI36
Build 3448,712,592 - 8,739,547NCBI
Celera48,487,239 - 8,514,366 (+)NCBICelera
Cytogenetic Map4p16.1NCBI
HuRef48,513,792 - 8,540,980 (+)NCBIHuRef
CHM1_148,592,625 - 8,619,813 (+)NCBICHM1_1
T2T-CHM13v2.048,572,626 - 8,599,700 (+)NCBIT2T-CHM13v2.0
Cpz
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39535,659,562 - 35,682,970 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl535,659,562 - 35,683,042 (-)EnsemblGRCm39 Ensembl
GRCm38535,502,218 - 35,525,626 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl535,502,218 - 35,525,698 (-)EnsemblGRCm38mm10GRCm38
MGSCv37535,844,867 - 35,868,275 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36535,819,196 - 35,842,396 (-)NCBIMGSCv36mm8
Celera532,977,576 - 33,000,943 (-)NCBICelera
Cytogenetic Map5B3NCBI
Cpz
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555142,572,173 - 2,586,038 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555142,572,075 - 2,590,274 (-)NCBIChiLan1.0ChiLan1.0
CPZ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.148,623,879 - 8,684,722 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl48,656,029 - 8,684,722 (+)Ensemblpanpan1.1panPan2
CPZ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1360,291,704 - 60,312,551 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl360,297,752 - 60,312,598 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha362,942,106 - 62,964,158 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0360,767,264 - 60,789,341 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl360,772,327 - 60,789,341 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1360,261,876 - 60,283,927 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0360,466,687 - 60,488,752 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0360,822,705 - 60,844,819 (+)NCBIUU_Cfam_GSD_1.0
Cpz
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528566,100,353 - 66,123,380 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493647719,792,738 - 19,825,066 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CPZ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl82,620,768 - 2,642,524 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.182,620,765 - 2,642,524 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CPZ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12744,516,632 - 44,546,475 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2744,516,800 - 44,546,337 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666051842,345 - 872,472 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cpz
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475524,075,939 - 24,088,088 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475524,069,650 - 24,088,180 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
RH134174  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21475,246,738 - 75,246,930 (+)MAPPERmRatBN7.2
Rnor_6.01480,425,996 - 80,426,187NCBIRnor6.0
Rnor_5.01480,052,089 - 80,052,280UniSTSRnor5.0
RGSC_v3.41480,880,385 - 80,880,576UniSTSRGSC3.4
Celera1474,175,132 - 74,175,323UniSTS
RH 3.4 Map14454.08UniSTS
Cytogenetic Map14q21UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143766971982669719Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143766971982669719Rat
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143905723783368335Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143999825175582726Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)145002321195023211Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1455624247100624247Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1456631369101631369Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)146875779683368335Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1470053989104886043Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1470053989104886043Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147341532392554092Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147341532392554092Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532395876975Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:73
Count of miRNA genes:67
Interacting mature miRNAs:71
Transcripts:ENSRNOT00000012109
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 3 3 12 21 6 3
Low 3 40 57 41 17 41 3 6 50 23 20 5 3
Below cutoff 3 2 2 20 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000012109   ⟹   ENSRNOP00000012109
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1475,223,723 - 75,246,945 (+)Ensembl
Rnor_6.0 Ensembl1480,403,001 - 80,426,245 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000108856   ⟹   ENSRNOP00000079374
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1475,223,605 - 75,246,945 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000113023   ⟹   ENSRNOP00000085858
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1475,223,605 - 75,246,945 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000119993   ⟹   ENSRNOP00000094872
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1475,231,215 - 75,246,945 (+)Ensembl
RefSeq Acc Id: NM_031766   ⟹   NP_113954
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21475,223,723 - 75,246,946 (+)NCBI
Rnor_6.01480,402,982 - 80,426,203 (+)NCBI
Rnor_5.01480,028,890 - 80,052,296 (+)NCBI
RGSC_v3.41480,857,371 - 80,880,592 (+)RGD
Celera1474,152,116 - 74,175,339 (+)RGD
Sequence:
RefSeq Acc Id: XM_006251151   ⟹   XP_006251213
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21475,223,692 - 75,246,824 (+)NCBI
Rnor_6.01480,402,946 - 80,426,203 (+)NCBI
Rnor_5.01480,028,890 - 80,052,296 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039092502   ⟹   XP_038948430
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21475,223,741 - 75,246,946 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_113954   ⟸   NM_031766
- Peptide Label: precursor
- UniProtKB: O54859 (UniProtKB/Swiss-Prot),   O54858 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006251213   ⟸   XM_006251151
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000012109   ⟸   ENSRNOT00000012109
RefSeq Acc Id: XP_038948430   ⟸   XM_039092502
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000094872   ⟸   ENSRNOT00000119993
RefSeq Acc Id: ENSRNOP00000085858   ⟸   ENSRNOT00000113023
RefSeq Acc Id: ENSRNOP00000079374   ⟸   ENSRNOT00000108856
Protein Domains
FZ

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O54858-F1-model_v2 AlphaFold O54858 1-652 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699390
Promoter ID:EPDNEW_R9915
Type:initiation region
Name:Cpz_1
Description:carboxypeptidase Z
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01480,402,982 - 80,403,042EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620496 AgrOrtholog
BioCyc Gene G2FUF-15324 BioCyc
Ensembl Genes ENSRNOG00000008947 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000012109 ENTREZGENE
  ENSRNOP00000012109.3 UniProtKB/TrEMBL
  ENSRNOP00000079374 ENTREZGENE
  ENSRNOP00000079374.1 UniProtKB/TrEMBL
  ENSRNOP00000085858 ENTREZGENE
  ENSRNOP00000085858.1 UniProtKB/TrEMBL
  ENSRNOP00000094872.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012109 ENTREZGENE
  ENSRNOT00000012109.5 UniProtKB/TrEMBL
  ENSRNOT00000108856 ENTREZGENE
  ENSRNOT00000108856.1 UniProtKB/TrEMBL
  ENSRNOT00000113023 ENTREZGENE
  ENSRNOT00000113023.1 UniProtKB/TrEMBL
  ENSRNOT00000119993.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.2000.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CarboxyPept-like_regulatory UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Frizzled_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Frizzled_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  M14_CPZ_CPD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:83575 UniProtKB/Swiss-Prot
NCBI Gene 83575 ENTREZGENE
Pfam Peptidase_M14 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF01392 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cpz PhenoGen
PRINTS CRBOXYPTASEA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CARBOXYPEPT_ZN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50038 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART FRI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Zn_pept UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49464 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF63501 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JSJ7_RAT UniProtKB/TrEMBL
  A0A8I5ZMK9_RAT UniProtKB/TrEMBL
  A0A8I6A134_RAT UniProtKB/TrEMBL
  A0A8I6GLC7_RAT UniProtKB/TrEMBL
  CBPZ_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  O54859 ENTREZGENE
UniProt Secondary O54859 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-26 Cpz  carboxypeptidase Z      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Cpz  carboxypeptidase Z      Symbol and Name status set to provisional 70820 PROVISIONAL