Pgam2 (phosphoglycerate mutase 2) - Rat Genome Database

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Gene: Pgam2 (phosphoglycerate mutase 2) Rattus norvegicus
Analyze
Symbol: Pgam2
Name: phosphoglycerate mutase 2
RGD ID: 3313
Description: Enables 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity. Involved in gluconeogenesis; response to mercury ion; and spermatogenesis. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in myoglobinuria. Orthologous to human PGAM2 (phosphoglycerate mutase 2); PARTICIPATES IN gluconeogenesis pathway; Fanconi syndrome pathway; fructose-1,6-bisphosphatase deficiency pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: BPG-dependent PGAM 2; D14Mgh1; muscle-specific phosphoglycerate mutase; PGAM-M; Pgmut; phosphoglycerate mutase 2 (muscle); phosphoglycerate mutase isozyme M
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81484,895,763 - 84,897,874 (-)NCBIGRCr8
mRatBN7.21480,681,796 - 80,683,907 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1480,681,776 - 80,683,940 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1485,084,326 - 85,086,436 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,324,429 - 86,326,539 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,773,751 - 82,775,861 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,045,005 - 86,047,116 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,044,969 - 86,047,162 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01486,736,814 - 86,738,925 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41486,466,055 - 86,468,166 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11486,485,199 - 86,487,311 (-)NCBI
Celera1479,566,749 - 79,568,860 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-hydroxypropanoic acid  (ISO)
3-chloropropane-1,2-diol  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
acrylamide  (EXP)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
aristolochic acids  (EXP)
atrazine  (EXP)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
C60 fullerene  (EXP)
cantharidin  (ISO)
carbon nanotube  (ISO)
ciguatoxin CTX1B  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
Cuprizon  (EXP)
dexamethasone  (ISO)
dextran sulfate  (ISO)
dioxygen  (ISO)
doxorubicin  (EXP,ISO)
fenvalerate  (EXP)
genistein  (EXP,ISO)
glyphosate  (ISO)
graphite  (ISO)
hydralazine  (ISO)
hydrogen sulfide  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
indometacin  (EXP)
iron dichloride  (ISO)
Monobutylphthalate  (ISO)
N(4)-hydroxycytidine  (ISO)
ochratoxin A  (EXP)
ozone  (EXP)
paracetamol  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
picrotoxin  (EXP)
pioglitazone  (ISO)
pirinixic acid  (ISO)
rac-lactic acid  (ISO)
rotenone  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sulfasalazine  (ISO)
sunitinib  (ISO)
titanium dioxide  (ISO)
Tributyltin oxide  (ISO)
triclosan  (ISO)
Triptolide  (EXP)
triptonide  (ISO)
triticonazole  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (ISO)

References

References - curated
# Reference Title Reference Citation
1. The muscle-specific phosphoglycerate mutase gene is specifically expressed in testis during spermatogenesis. Broceno C, etal., Eur J Biochem. 1995 Feb 1;227(3):629-35.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Inactivation of type MM phosphoglycerate mutase by sulfhydryl group reagents during facial embryogenesis. Granstrom G and Mangs H, Acta Odontol Scand. 1988 Oct;46(5):273-9.
4. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
12. The histidine phosphatase superfamily: structure and function. Rigden DJ Biochem J. 2008 Jan 15;409(2):333-48.
13. The gene encoding rat phosphoglycerate mutase subunit M: cloning and promoter analysis in skeletal muscle cells. Ruiz-Lozano P, etal., Gene 1994 Sep 30;147(2):243-8.
14. Monochloroacetic acid inhibits liver gluconeogenesis by inactivating glyceraldehyde-3-phosphate dehydrogenase. Sakai A, etal., Chem Res Toxicol. 2005 Feb;18(2):277-82.
15. Gene-based anchoring of the rat genetic linkage and cytogenetic maps: new regional localizations, orientation of the linkage groups, and insights into mammalian chromosome evolution. Szpirer C, etal., Mamm Genome 1998 Sep;9(9):721-34
16. The molecular genetic basis of muscle phosphoglycerate mutase (PGAM) deficiency. Tsujino S, etal., Am J Hum Genet. 1993 Mar;52(3):472-7.
17. Location of phosphoglycerate mutase in rat skeletal muscle. An immunocytochemical and biochemical study. Urena JM, etal., Eur J Cell Biol. 1990 Feb;51(1):151-6.
Additional References at PubMed
PMID:2558656   PMID:2824255   PMID:4827367   PMID:6262916   PMID:11250083   PMID:15665293   PMID:21630459   PMID:23117660   PMID:23533145   PMID:29476059  


Genomics

Comparative Map Data
Pgam2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81484,895,763 - 84,897,874 (-)NCBIGRCr8
mRatBN7.21480,681,796 - 80,683,907 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1480,681,776 - 80,683,940 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1485,084,326 - 85,086,436 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,324,429 - 86,326,539 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,773,751 - 82,775,861 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,045,005 - 86,047,116 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,044,969 - 86,047,162 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01486,736,814 - 86,738,925 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41486,466,055 - 86,468,166 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11486,485,199 - 86,487,311 (-)NCBI
Celera1479,566,749 - 79,568,860 (-)NCBICelera
Cytogenetic Map14q21NCBI
PGAM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38744,062,727 - 44,065,567 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl744,062,727 - 44,065,567 (-)EnsemblGRCh38hg38GRCh38
GRCh37744,102,326 - 44,105,166 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36744,068,851 - 44,071,688 (-)NCBINCBI36Build 36hg18NCBI36
Build 34743,875,566 - 43,878,403NCBI
Celera744,200,271 - 44,203,131 (-)NCBICelera
Cytogenetic Map7p13NCBI
HuRef743,987,609 - 43,990,469 (-)NCBIHuRef
CHM1_1744,106,200 - 44,109,060 (-)NCBICHM1_1
T2T-CHM13v2.0744,221,224 - 44,224,064 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2744,141,816 - 44,144,674 (-)NCBI
Pgam2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,751,637 - 5,753,796 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl115,751,640 - 5,753,733 (-)EnsemblGRCm39 Ensembl
GRCm38115,801,637 - 5,803,796 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,801,640 - 5,803,733 (-)EnsemblGRCm38mm10GRCm38
MGSCv37115,701,640 - 5,703,799 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36115,701,647 - 5,703,736 (-)NCBIMGSCv36mm8
Celera116,291,798 - 6,293,956 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map113.87NCBI
Pgam2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554567,909,891 - 7,912,116 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554567,909,891 - 7,912,116 (+)NCBIChiLan1.0ChiLan1.0
PGAM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2648,973,896 - 48,983,253 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1797,297,291 - 97,301,591 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0744,776,722 - 44,780,248 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1744,843,067 - 44,846,274 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl744,843,067 - 44,845,984 (-)Ensemblpanpan1.1panPan2
PGAM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha162,007,972 - 2,010,428 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01614,851,571 - 14,854,027 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1614,851,574 - 14,854,031 (+)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.01614,482,753 - 14,485,209 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01614,463,237 - 14,465,693 (+)NCBIUU_Cfam_GSD_1.0
Pgam2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511899,810,197 - 99,812,642 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647819,020,048 - 19,024,394 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647819,021,928 - 19,026,110 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PGAM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1848,710,347 - 48,713,862 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11848,693,832 - 48,712,787 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21853,423,580 - 53,425,838 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PGAM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12114,604,127 - 14,609,196 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2114,606,401 - 14,609,158 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660627,905,467 - 7,908,316 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pgam2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247407,947,742 - 7,950,956 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247407,947,738 - 7,949,900 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pgam2
7 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:43
Count of miRNA genes:42
Interacting mature miRNAs:43
Transcripts:ENSRNOT00000018227
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)147995092195876975Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)146875779683368335Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1470053989104886043Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147341532392554092Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532395876975Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1456631369101631369Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1470053989104886043Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147341532392554092Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1455624247100624247Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143766971982669719Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)145002321195023211Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143905723783368335Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143766971982669719Rat

Markers in Region
D14Mgh1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21480,684,833 - 80,684,938 (+)MAPPERmRatBN7.2
Rnor_6.01486,048,043 - 86,048,147NCBIRnor6.0
Rnor_5.01486,739,852 - 86,739,956UniSTSRnor5.0
RGSC_v3.41486,469,093 - 86,469,197UniSTSRGSC3.4
Celera1479,569,638 - 79,569,742UniSTS
RH 3.4 Map14571.5UniSTS
RH 3.4 Map14571.5RGD
RH 2.0 Map14702.9RGD
SHRSP x BN Map1444.8999RGD
Cytogenetic Map14q21UniSTS
Cytogenetic Map14q21-q22UniSTS
D14Rat19  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21480,684,320 - 80,684,482 (+)MAPPERmRatBN7.2
Rnor_6.01486,047,530 - 86,047,691NCBIRnor6.0
Rnor_5.01486,739,339 - 86,739,500UniSTSRnor5.0
RGSC_v3.41486,468,542 - 86,468,937RGDRGSC3.4
RGSC_v3.41486,468,580 - 86,468,741UniSTSRGSC3.4
RGSC_v3.11486,487,725 - 86,487,886RGD
RH 3.4 Map14571.5RGD
RH 3.4 Map14571.5UniSTS
RH 2.0 Map14702.7RGD
SHRSP x BN Map1445.38RGD
Cytogenetic Map14q21-q22UniSTS
Cytogenetic Map14q21UniSTS
AW527377  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21480,682,949 - 80,683,113 (+)MAPPERmRatBN7.2
Rnor_6.01486,046,159 - 86,046,322NCBIRnor6.0
Rnor_5.01486,737,968 - 86,738,131UniSTSRnor5.0
RGSC_v3.41486,467,209 - 86,467,372UniSTSRGSC3.4
Celera1479,567,903 - 79,568,066UniSTS
RH 3.4 Map14571.5UniSTS
Cytogenetic Map14q21UniSTS
Cytogenetic Map14q21-q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 60 66 65 34 25 34 6 193 97 40 45 55 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_017328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC128636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HH770049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HH770393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M31835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z17319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000018227   ⟹   ENSRNOP00000018227
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1480,681,776 - 80,683,940 (-)Ensembl
Rnor_6.0 Ensembl1486,044,969 - 86,047,162 (-)Ensembl
RefSeq Acc Id: NM_017328   ⟹   NP_059024
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,895,763 - 84,897,874 (-)NCBI
mRatBN7.21480,681,796 - 80,683,907 (-)NCBI
Rnor_6.01486,045,005 - 86,047,116 (-)NCBI
Rnor_5.01486,736,814 - 86,738,925 (-)NCBI
RGSC_v3.41486,466,055 - 86,468,166 (-)RGD
Celera1479,566,749 - 79,568,860 (-)RGD
Sequence:
RefSeq Acc Id: NP_059024   ⟸   NM_017328
- UniProtKB: P16290 (UniProtKB/Swiss-Prot),   A6IKP7 (UniProtKB/TrEMBL),   A6IKP6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018227   ⟸   ENSRNOT00000018227

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P16290-F1-model_v2 AlphaFold P16290 1-253 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699462
Promoter ID:EPDNEW_R9986
Type:initiation region
Name:Pgam2_1
Description:phosphoglycerate mutase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01486,047,132 - 86,047,192EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3313 AgrOrtholog
BioCyc Gene G2FUF-15126 BioCyc
BioCyc Pathway ANAGLYCOLYSIS-PWY [glycolysis III (from glucose)] BioCyc
  PWY-6405 [Rapoport-Luebering glycolytic shunt] BioCyc
  PWY66-399 [gluconeogenesis III] BioCyc
BioCyc Pathway Image ANAGLYCOLYSIS-PWY BioCyc
  PWY-6405 BioCyc
  PWY66-399 BioCyc
Ensembl Genes ENSRNOG00000013532 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00055029113 UniProtKB/Swiss-Prot
  ENSRNOG00060031689 UniProtKB/Swiss-Prot
  ENSRNOG00065020304 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000018227.8 UniProtKB/Swiss-Prot
  ENSRNOT00055050416 UniProtKB/Swiss-Prot
  ENSRNOT00060054903 UniProtKB/Swiss-Prot
  ENSRNOT00065034300 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.1240 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro His_Pase_superF_clade-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  His_PPase_superfam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PG/BPGM_mutase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Phosphogly_mut1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24959 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 24959 ENTREZGENE
PANTHER PHOSPHOGLYCERATE MUTASE UniProtKB/TrEMBL
  PHOSPHOGLYCERATE MUTASE 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11931 UniProtKB/Swiss-Prot
Pfam His_Phos_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pgam2 PhenoGen
PIRSF 6PFK_2-Ptase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PG_MUTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013532 RatGTEx
  ENSRNOG00055029113 RatGTEx
  ENSRNOG00060031689 RatGTEx
  ENSRNOG00065020304 RatGTEx
SMART PGAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Phosphoglycerate mutase-like UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt A6IKP6 ENTREZGENE, UniProtKB/TrEMBL
  A6IKP7 ENTREZGENE, UniProtKB/TrEMBL
  A6IKP8_RAT UniProtKB/TrEMBL
  P16290 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-02 Pgam2  phosphoglycerate mutase 2  Pgam2  phosphoglycerate mutase 2 (muscle)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-17 Pgam2  phosphoglycerate mutase 2 (muscle)  Pgam2  phosphoglycerate mutase 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Pgam2  phosphoglycerate mutase 2      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_function interconverts 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction