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Gene: Htra3 (HtrA serine peptidase 3) Rattus norvegicus
Symbol: Htra3
Name: HtrA serine peptidase 3
Description: Predicted to have endopeptidase activity and serine-type peptidase activity. Predicted to be involved in negative regulation of BMP signaling pathway; negative regulation of transforming growth factor beta receptor signaling pathway; and proteolysis. Predicted to localize to the extracellular region. Orthologous to human HTRA3 (HtrA serine peptidase 3); INTERACTS WITH 3,7-dihydropurine-6-thione; 3-chloropropane-1,2-diol; C60 fullerene.
Type: protein-coding
RefSeq Status: INFERRED
Also known as: high-temperature requirement factor A3; LOC360959; pregnancy-related serine protease; probable serine protease HTRA3; RGD1308120; serine protease HTRA3; similar to toll-associated serine protease
Homo sapiens (human) : HTRA3 (HtrA serine peptidase 3)  HGNC  Alliance
Mus musculus (house mouse) : Htra3 (HtrA serine peptidase 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Htra3 (HtrA serine peptidase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : HTRA3 (HtrA serine peptidase 3)
Canis lupus familiaris (dog) : HTRA3 (HtrA serine peptidase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Htra3 (HtrA serine peptidase 3)
Sus scrofa (pig) : HTRA3 (HtrA serine peptidase 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01480,248,140 - 80,276,534 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01479,875,405 - 79,903,558 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41480,702,016 - 80,730,742 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11480,704,572 - 80,732,620 (+)NCBI
Celera1473,999,661 - 74,027,836 (+)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Htra3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308120
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.