Hs3st1 (heparan sulfate-glucosamine 3-sulfotransferase 1) - Rat Genome Database

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Gene: Hs3st1 (heparan sulfate-glucosamine 3-sulfotransferase 1) Rattus norvegicus
Analyze
Symbol: Hs3st1
Name: heparan sulfate-glucosamine 3-sulfotransferase 1
RGD ID: 71084
Description: Predicted to enable [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity. Predicted to be involved in glycosaminoglycan biosynthetic process and heparan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi lumen. Predicted to be active in Golgi apparatus. Orthologous to human HS3ST1 (heparan sulfate-glucosamine 3-sulfotransferase 1); PARTICIPATES IN heparan sulfate biosynthetic pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 3OST-I; heparan sulfate (glucosamine) 3-O-sulfotransferase 1; heparan sulfate 3-O-sulfotransferase 1; heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1; heparan sulfate glucosamine 3-O-sulfotransferase 1; heparan sulfate glucosamine 3-O-sulfotransferase I
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81475,398,101 - 75,429,628 (+)NCBIGRCr8
mRatBN7.21471,185,826 - 71,223,263 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1471,185,682 - 71,223,248 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1475,621,414 - 75,651,140 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01476,869,044 - 76,898,770 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01473,309,433 - 73,339,159 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01475,880,410 - 75,881,346 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1475,852,060 - 75,882,693 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01475,872,397 - 75,873,333 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41476,438,219 - 76,439,157 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11476,440,619 - 76,441,546 (+)NCBI
Celera1470,167,035 - 70,167,971 (+)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2,4-trimethylbenzene  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
clobetasol  (ISO)
corticosterone  (EXP)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cytarabine  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
furan  (EXP)
gentamycin  (EXP)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
mercury dibromide  (ISO)
naphthalene  (ISO)
naphthalenes  (EXP)
nickel atom  (ISO)
omega-6 fatty acid  (ISO)
ozone  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
phenylmercury acetate  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triptonide  (ISO)
valproic acid  (EXP,ISO)
vanadyl sulfate  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
Golgi apparatus  (IEA,ISO)
Golgi lumen  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Expression of N-deacetylase/sulfotransferase and 3-O-sulfotransferase in rat alveolar type II cells. Li ZY, etal., Am J Physiol Lung Cell Mol Physiol 2000 Aug;279(2):L292-301.
4. Gene Data Set MGD Curation, June 12, 2002
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:20500673  


Genomics

Comparative Map Data
Hs3st1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81475,398,101 - 75,429,628 (+)NCBIGRCr8
mRatBN7.21471,185,826 - 71,223,263 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1471,185,682 - 71,223,248 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1475,621,414 - 75,651,140 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01476,869,044 - 76,898,770 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01473,309,433 - 73,339,159 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01475,880,410 - 75,881,346 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1475,852,060 - 75,882,693 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01475,872,397 - 75,873,333 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41476,438,219 - 76,439,157 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11476,440,619 - 76,441,546 (+)NCBI
Celera1470,167,035 - 70,167,971 (+)NCBICelera
Cytogenetic Map14q21NCBI
HS3ST1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38411,393,150 - 11,434,327 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl411,393,150 - 11,429,564 (-)EnsemblGRCh38hg38GRCh38
GRCh37411,394,774 - 11,430,518 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36411,009,086 - 11,039,635 (-)NCBINCBI36Build 36hg18NCBI36
Build 34411,076,256 - 11,106,806NCBI
Celera411,864,401 - 11,894,954 (-)NCBICelera
Cytogenetic Map4p15.33NCBI
HuRef410,732,784 - 10,763,337 (-)NCBIHuRef
CHM1_1411,398,055 - 11,428,601 (-)NCBICHM1_1
T2T-CHM13v2.0411,369,209 - 11,410,393 (-)NCBIT2T-CHM13v2.0
Hs3st1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39539,771,278 - 39,802,791 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl539,771,278 - 39,912,818 (-)EnsemblGRCm39 Ensembl
GRCm38539,613,935 - 39,645,592 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl539,613,935 - 39,755,475 (-)EnsemblGRCm38mm10GRCm38
MGSCv37540,005,174 - 40,035,870 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36539,902,184 - 40,043,724 (-)NCBIMGSCv36mm8
Celera537,077,022 - 37,107,666 (-)NCBICelera
Cytogenetic Map5B3NCBI
cM Map521.14NCBI
Hs3st1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555491,591,605 - 1,623,681 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555491,591,605 - 1,623,681 (+)NCBIChiLan1.0ChiLan1.0
HS3ST1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2311,630,308 - 11,666,199 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1411,838,797 - 11,874,689 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v045,797,803 - 5,829,976 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1411,108,089 - 11,139,043 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl411,108,374 - 11,109,297 (-)Ensemblpanpan1.1panPan2
HS3ST1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1368,306,512 - 68,336,879 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha370,831,990 - 70,862,330 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0368,922,300 - 68,952,641 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl368,950,937 - 68,951,854 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1368,330,085 - 68,360,403 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0368,492,806 - 68,523,133 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0368,864,624 - 68,894,997 (+)NCBIUU_Cfam_GSD_1.0
Hs3st1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528561,974,067 - 62,004,935 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647715,676,178 - 15,706,067 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647715,676,151 - 15,706,067 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HS3ST1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl87,389,780 - 7,423,869 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.187,389,774 - 7,424,558 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
HS3ST1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12738,683,032 - 38,716,222 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2738,714,570 - 38,715,493 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604785,456,975 - 85,489,159 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hs3st1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475520,035,055 - 20,039,967 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475520,010,126 - 20,039,988 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hs3st1
212 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:25
Count of miRNA genes:24
Interacting mature miRNAs:25
Transcripts:ENSRNOT00000014078
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143766971982669719Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143766971982669719Rat
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143905723783368335Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143999825175582726Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)145002321195023211Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1455624247100624247Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1456631369101631369Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)146875779683368335Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1470053989104886043Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1470053989104886043Rat

Markers in Region
D5Wsu110e  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21471,216,136 - 71,216,360 (+)MAPPERmRatBN7.2
Rnor_6.01475,881,538 - 75,881,761NCBIRnor6.0
Rnor_5.01475,873,525 - 75,873,748UniSTSRnor5.0
RGSC_v3.41476,439,347 - 76,439,570UniSTSRGSC3.4
Celera1470,168,163 - 70,168,386UniSTS
Cytogenetic Map14q21UniSTS
AA963021  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21471,215,924 - 71,216,143 (+)MAPPERmRatBN7.2
Rnor_6.01475,881,326 - 75,881,544NCBIRnor6.0
Rnor_5.01475,873,313 - 75,873,531UniSTSRnor5.0
RGSC_v3.41476,439,135 - 76,439,353UniSTSRGSC3.4
Celera1470,167,951 - 70,168,169UniSTS
Cytogenetic Map14q21UniSTS
Hs3st1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21471,215,206 - 71,215,411 (+)MAPPERmRatBN7.2
Rnor_6.01475,880,608 - 75,880,812NCBIRnor6.0
Rnor_5.01475,872,595 - 75,872,799UniSTSRnor5.0
Celera1470,167,233 - 70,167,437UniSTS
Cytogenetic Map14q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 11 54 7 8 1
Low 3 43 48 32 8 32 8 11 20 28 31 10 8
Below cutoff 9 9 9 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000014078   ⟹   ENSRNOP00000014077
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1475,880,410 - 75,881,348 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000075975   ⟹   ENSRNOP00000068250
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1471,214,565 - 71,216,419 (+)Ensembl
Rnor_6.0 Ensembl1475,852,060 - 75,882,693 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000098441   ⟹   ENSRNOP00000091056
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1471,186,469 - 71,223,248 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000105004   ⟹   ENSRNOP00000094638
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1471,185,682 - 71,223,248 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000109235   ⟹   ENSRNOP00000081036
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1471,207,136 - 71,223,248 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000114048   ⟹   ENSRNOP00000082460
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1471,201,465 - 71,223,128 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000114492   ⟹   ENSRNOP00000078209
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1471,208,130 - 71,223,248 (+)Ensembl
RefSeq Acc Id: NM_053391   ⟹   NP_445843
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81475,398,973 - 75,428,701 (+)NCBI
mRatBN7.21471,186,637 - 71,216,365 (+)NCBI
Rnor_6.01475,880,410 - 75,881,346 (+)NCBI
Rnor_5.01475,872,397 - 75,873,333 (+)NCBI
RGSC_v3.41476,438,219 - 76,439,157 (+)RGD
Celera1470,167,035 - 70,167,971 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039092506   ⟹   XP_038948434
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81475,398,101 - 75,429,628 (+)NCBI
mRatBN7.21471,185,826 - 71,223,263 (+)NCBI
RefSeq Acc Id: XM_063273682   ⟹   XP_063129752
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81475,398,153 - 75,429,628 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_445843   ⟸   NM_053391
- Peptide Label: precursor
- UniProtKB: G3V7E2 (UniProtKB/TrEMBL),   A6IJR8 (UniProtKB/TrEMBL),   A0A221CBA4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000068250   ⟸   ENSRNOT00000075975
RefSeq Acc Id: ENSRNOP00000014077   ⟸   ENSRNOT00000014078
RefSeq Acc Id: XP_038948434   ⟸   XM_039092506
- Peptide Label: isoform X1
- UniProtKB: G3V7E2 (UniProtKB/TrEMBL),   A6IJR8 (UniProtKB/TrEMBL),   A0A221CBA4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000094638   ⟸   ENSRNOT00000105004
RefSeq Acc Id: ENSRNOP00000091056   ⟸   ENSRNOT00000098441
RefSeq Acc Id: ENSRNOP00000081036   ⟸   ENSRNOT00000109235
RefSeq Acc Id: ENSRNOP00000078209   ⟸   ENSRNOT00000114492
RefSeq Acc Id: ENSRNOP00000082460   ⟸   ENSRNOT00000114048
RefSeq Acc Id: XP_063129752   ⟸   XM_063273682
- Peptide Label: isoform X1
- UniProtKB: A6IJR8 (UniProtKB/TrEMBL),   G3V7E2 (UniProtKB/TrEMBL)
Protein Domains
Sulfotransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9ESG5-F1-model_v2 AlphaFold Q9ESG5 1-311 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:71084 AgrOrtholog
BioCyc Gene G2FUF-15451 BioCyc
Ensembl Genes ENSRNOG00000010598 Ensembl
  ENSRNOG00000068537 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000075975.2 UniProtKB/TrEMBL
  ENSRNOT00000098441 ENTREZGENE
  ENSRNOT00000098441.1 UniProtKB/TrEMBL
  ENSRNOT00000105004.1 UniProtKB/TrEMBL
  ENSRNOT00000109235.1 UniProtKB/TrEMBL
  ENSRNOT00000114048.1 UniProtKB/TrEMBL
  ENSRNOT00000114492.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro NST/OST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sulfotransferase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:84406 UniProtKB/Swiss-Prot
NCBI Gene 84406 ENTREZGENE
PANTHER HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10605 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Sulfotransfer_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hs3st1 PhenoGen
RatGTEx ENSRNOG00000010598 RatGTEx
  ENSRNOG00000068537 RatGTEx
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A221CBA4 ENTREZGENE, UniProtKB/TrEMBL
  A6IJR8 ENTREZGENE, UniProtKB/TrEMBL
  G3V7E2 ENTREZGENE, UniProtKB/TrEMBL
  HS3S1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-09 Hs3st1  heparan sulfate-glucosamine 3-sulfotransferase 1  Hs3st1  heparan sulfate (glucosamine) 3-O-sulfotransferase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-07-09 Hs3st1  heparan sulfate (glucosamine) 3-O-sulfotransferase 1      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in alveolar type II cells 70765